Increase in visceral adipose tissue in a woman living with HIV after introduction of integrase strand transfer inhibitor.

Abstract:

:Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral drugs with high virologic efficacy and excellent tolerability. Recent evidence showed a possible link of dolutegravir-based regimens with weight gain, and a relationship between raltegravir use and changes in adipose tissue density and metabolic abnormalities, with an increased cardiovascular risk, has been suggested. We describe a case where dolutegravir monotherapy led to a decrease in adipose tissue density.

journal_name

Int J STD AIDS

authors

Piacentini D,Lanzafame M,Rizzardo S,Chiesi S,Lattuada E,Mehrabi S,Zamboni G,Mazzi R,Tacconelli E,Vento S

doi

10.1177/0956462420955075

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

1407-1410

issue

14

eissn

0956-4624

issn

1758-1052

journal_volume

31

pub_type

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