Abstract:
:The internal carotid artery (ICA) has been proposed as an alternative site to the middle cerebral artery (MCA) to measure dynamic cerebral autoregulation (dCA) using transcranial Doppler ultrasound (TCD). Our aim was to test the inter-operator reproducibility of dCA assessment in the ICA and the effect of interaction amongst different variables (artery source × operator × intra-subject variability). Two operators measured blood flow velocity using TCD at the ICA and MCA simultaneously on each side in 12 healthy volunteers. The autoregulation index (ARI) was estimated by transfer function analysis. A two-way repeated measurements ANOVA with post-hoc Tukey tested the difference between ARI by different operators and interaction effects were analysed based on the generalized linear model. In this healthy population, no significant differences between operator and no interaction effects were identified amongst the different variables. This study reinforced the validity of using the ICA as an alternative site for the assessment of dCA. Further work is needed to confirm and extend our findings, particularly to disease populations.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Nogueira RC,Saeed NP,Bor-Seng-Shu E,Teixeira MJ,Robinson TG,Panerai RBdoi
10.1016/j.medengphy.2016.03.007subject
Has Abstractpub_date
2016-07-01 00:00:00pages
690-694issue
7eissn
1350-4533issn
1873-4030pii
S1350-4533(16)30040-6journal_volume
38pub_type
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