Response to Comment on "Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography".

abstract：:The use of conventional fluorescence microscopy for characterizing tissue pathological states is limited by overlapping spectra and the dependence on excitation power and fluorophore concentration. Fluorescence lifetime imaging microscopy (FLIM) can overcome these limitations due to its insensitivity to fluorophore co...

journal_title：Journal of biophotonics

authors： Gu J,Fu CY,Ng BK,Gulam Razul Ss,Lim SK

更新日期：2014-07-01 00:00:00

abstract：:Laser therapy, also known as Photobiomodulation (PBM) is indicated to reduce pain associated with different pathologies and applied using protocols that vary in wavelength, irradiance and fluence. Its mechanisms of action are still unclear and possibly able to directly impact on pain transmission, reducing nociceptor ...

journal_title：Journal of biophotonics

authors： Zupin L,Ottaviani G,Rupel K,Biasotto M,Zacchigna S,Crovella S,Celsi F

更新日期：2019-10-01 00:00:00

abstract：:The purpose of this study was to evaluate early vascular and tomographic changes in the retina of diabetic patients using artificial intelligence (AI). The study included 74 age-matched normal eyes, 171 diabetic eyes without retinopathy (DWR) eyes and 69 mild non-proliferative diabetic retinopathy (NPDR) eyes. All pat...

journal_title：Journal of biophotonics

authors： Govindaswamy N,Ratra D,Dalan D,Doralli S,Tirumalai AA,Nagarajan R,Mochi T,Shetty N,Sinha Roy A

更新日期：2020-09-01 00:00:00

abstract：:Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A...

journal_title：Journal of biophotonics

authors： Carrasco-Zevallos O,Shelton RL,Kim W,Pearson J,Applegate BE

更新日期：2015-01-01 00:00:00

abstract：:Compared to conventional techniques, Laser surgery procedures provide a number of advantages, but may be associated with an increased risk of iatrogenic damage to important anatomical structures. The type of tissue ablated in the focus spot is unknown. Laser-Induced Breakdown-Spectroscopy (LIBS) has the potential to g...

journal_title：Journal of biophotonics

authors： Rohde M,Mehari F,Klämpfl F,Adler W,Neukam FW,Schmidt M,Stelzle F

更新日期：2017-10-01 00:00:00

abstract：:Noninvasive body shaping is becoming a growing demand. The aim of this study was to investigate the efficacy and safety of the combined treatments of 1064 nm Nd:YAG and 2940 nm Er:YAG in noninvasive lipolysis and skin tightening. Ten females were enrolled, and all women's side of the waist or the lower part of the abd...

journal_title：Journal of biophotonics

authors： Vas K,Besenyi Z,Urbán S,Badawi A,Pávics L,Erős G,Kemény L

更新日期：2019-09-01 00:00:00

abstract：:A plastic optical fibre biosensor based on surface plasmon resonance for the detection of C-reactive protein (CRP) in serum is proposed. The biosensor was integrated into a home-made thermo-stabilized microfluidic system that allows avoiding any thermal and/or mechanical fluctuation and maintaining the best stable con...

journal_title：Journal of biophotonics

authors： Aray A,Chiavaioli F,Arjmand M,Trono C,Tombelli S,Giannetti A,Cennamo N,Soltanolkotabi M,Zeni L,Baldini F

更新日期：2016-10-01 00:00:00

abstract：:Ionizing radiation (IR) induces DNA damage and low-level laser therapy (LLLT) has been investigated to prevent or repair detrimental outcomes resulting from IR exposure. Few in vitro studies, however, explore the biological mechanisms underlying those LLLT benefits. Thus, in this work, fibroblasts and tumor cells are ...

journal_title：Journal of biophotonics

authors： Ramos Silva C,Cabral FV,de Camargo CF,Núñez SC,Mateus Yoshimura T,de Lima Luna AC,Maria DA,Ribeiro MS

更新日期：2016-12-01 00:00:00

abstract：:A conceptually new type of corneal inlays for a customized treatment of presbyopia is presented. The diffractive inlay consists on a small aperture disc having an array of micro-holes distributed inside the open zones of a Fresnel zone plate. In this way, the central hole of the disc lets pass the zero order diffracti...

journal_title：Journal of biophotonics

authors： Furlan WD,García-Delpech S,Udaondo P,Remón L,Ferrando V,Monsoriu JA

更新日期：2017-09-01 00:00:00

abstract：:Clinicians need a way to rapidly and reliably test the correct functioning of near-infrared spectroscopy (NIRS)-based oximeters. Therefore, optical phantoms for quality assessment of NIRS oximeters are needed. The fabrication of such phantoms that mimic the optical properties of biological tissue in the NIR range repr...

journal_title：Journal of biophotonics

authors： Tomm N,Ahnen L,Isler H,Kleiser S,Karen T,Ostojic D,Wolf M,Scholkmann F

更新日期：2019-04-01 00:00:00

abstract：:Articular cartilage posesses unique material properties due to a complex depth-dependent composition of sub-components. Raman spectroscopy has proven valuable in quantifying this composition through cartilage cross-sections. However, cross-sectioning requires tissue destruction and is not practical in situ. In this wo...

journal_title：Journal of biophotonics

authors： Mason D,Murugkar S,Speirs AD

更新日期：2021-01-01 00:00:00

abstract：:The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...

journal_title：Journal of biophotonics

authors： Ranjit S,Malacrida L,Stakic M,Gratton E

更新日期：2019-11-01 00:00:00

abstract：:FTIR spectroscopy is a powerful diagnostic tool that can also derive biochemical signatures of a wide range of cellular materials, such as cytology, histology, live cells, and biofluids. However, while classification is a well-established subject, biomarker identification lacks standards and validation of its methods....

journal_title：Journal of biophotonics

authors： Trevisan J,Park J,Angelov PP,Ahmadzai AA,Gajjar K,Scott AD,Carmichael PL,Martin FL

更新日期：2014-04-01 00:00:00

abstract：:Endoscopy has been widely used in biomedical imaging and integrated with various optical and acoustic imaging modalities. Photoacoustic imaging (PAI), one of the fastest growing biomedical imaging modalities, is a noninvasive and nonionizing method that owns rich optical contrast, deep acoustic penetration depth, mult...

journal_title：Journal of biophotonics

authors： Guo H,Li Y,Qi W,Xi L

更新日期：2020-12-01 00:00:00

abstract：:The processes associated with pollen germination were studied in vitro for two tree species, Salix caprea and Fraxinus excelsior under different nutrient conditions. The results provide evidence of changes in chemical composition of the pollen grains during germination. From the comparison of spectra of the pollen gra...

journal_title：Journal of biophotonics

authors： Schulte F,Panne U,Kneipp J

更新日期：2010-08-01 00:00:00

abstract：:We report a compact, cost-effective tuned amplifier for frequency-selective amplification of the modulated signal in heterodyne detected nonlinear optical microscopy. Our method improved the signal to noise ratio by an order of magnitude compared to conventional lock-in detection, as demonstrated through stimulated Ra...

journal_title：Journal of biophotonics

authors： Slipchenko MN,Oglesbee RA,Zhang D,Wu W,Cheng JX

更新日期：2012-10-01 00:00:00

abstract：:Pancreatic islet isolation from donor pancreases is an essential step for the transplantation of insulin-secreting β-cells as a therapy to treat type 1 diabetes mellitus. This process however damages islet basement membranes, which can lead to islet dysfunction or death. Posttransplantation, islets are further stresse...

journal_title：Journal of biophotonics

authors： Zbinden A,Carvajal Berrio DA,Urbanczyk M,Layland SL,Bosch M,Fliri S,Lu CE,Jeyagaran A,Loskill P,Duffy GP,Schenke-Layland K

更新日期：2020-12-01 00:00:00

abstract：:We present a noninvasive and noncontacting biosensor using Wavelength Modulated Differential Photothermal Radiometry (WM-DPTR) to monitor blood glucose concentration (BGC) through interstitial fluid (ISF) probing in human middle fingers. WM-DPTR works in the interference-free mid-infrared range with differential wavel...

journal_title：Journal of biophotonics

authors： Guo X,Zhang D,Shojaei-Asanjan K,Sivagurunathan K,Melnikov A,Song P,Mandelis A

更新日期：2019-07-01 00:00:00

abstract：:The aim of this study is to identify changes in scattering with optical coherence tomography (OCT) and relate these measurements with mitochondrial changes during the initiation of apoptosis. Human retinal pigment epithelial cells were cultured and apoptosis was induced using 10% alcohol. Using the attenuation coeffic...

journal_title：Journal of biophotonics

authors： de Bruin DM,Broekgaarden M,van Gemert MJ,Heger M,de la Rosette JJ,Van Leeuwen TG,Faber DJ

更新日期：2016-09-01 00:00:00

abstract：:Monitoring living cells in real-time is important in order to unravel complex dynamic processes in life sciences. In particular the dynamics of initiation and progression of degenerative diseases is intensely studied. In atherosclerosis the thickening of arterial walls is related to high lipid levels in the blood stre...

journal_title：Journal of biophotonics

authors： Stiebing C,Meyer T,Rimke I,Matthäus C,Schmitt M,Lorkowski S,Popp J

更新日期：2017-09-01 00:00:00

abstract：:Near-infrared light allows measuring tissue oxygenation. These measurements relay on oxygenation-dependent absorption spectral changes. However, the tissue scattering, which is also spectral dependent, introduces an intrinsic error. Most methods focus on the volume reflectance from a semi-infinite sample. We have prop...

journal_title：Journal of biophotonics

authors： Duadi H,Feder I,Fixler D

更新日期：2018-04-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) is highly sensitive and label-free analytical technique based on Raman spectroscopy aided by field-multiplying plasmonic nanostructures. We report the use of SERS measurements of patient urine in conjunction with biostatistical algorithms to assess the treatment response of pro...

journal_title：Journal of biophotonics

authors： Ma Y,Chi J,Zheng Z,Attygalle A,Kim IY,Du H

更新日期：2021-01-01 00:00:00

abstract：:Dynamic follow-up of exogenous molecules permeation through the skin is one among many competing applications for confocal Raman microspectroscopy. Previous studies showed the feasibility of tracking actives through the skin; the next step should be recording in vivo kinetics. Thus, we conducted a study to evaluate th...

journal_title：Journal of biophotonics

authors： Tfaili S,Josse G,Angiboust JF,Manfait M,Piot O

更新日期：2014-09-01 00:00:00

abstract：:Acridine orange (AO) staining is used to diagnose DNA fragmentation status in sperm cells. Interferometric phase microscopy (IPM) is an optical imaging method based on digital holographic microscopy that provides quantitative morphological and refractive index imaging of cells in vitro without the need for staining. W...

journal_title：Journal of biophotonics

authors： Barnea I,Karako L,Mirsky SK,Levi M,Balberg M,Shaked NT

更新日期：2018-11-01 00:00:00

abstract：:This contribution covers recent original research papers in the biophotonics field. The content is organized into main techniques such as multiphoton microscopy, Raman spectroscopy, infrared spectroscopy, optical coherence tomography and photoacoustic tomography, and their applications in the context of fluid, cell, t...

journal_title：Journal of biophotonics

authors： Krafft C

更新日期：2016-12-01 00:00:00

abstract：:We present a pseudo-real-time retinal layer segmentation for high-resolution Sensorless Adaptive Optics-Optical Coherence Tomography (SAO-OCT). Our pseudo-real-time segmentation method is based on Dijkstra's algorithm that uses the intensity of pixels and the vertical gradient of the image to find the minimum cost in ...

journal_title：Journal of biophotonics

authors： Janpongsri W,Huang J,Ng R,Wahl DJ,Sarunic MV,Jian Y

更新日期：2020-08-01 00:00:00

abstract：:Semen analysis is performed for evaluation of fertility disorders, however it is susceptible to subjectivity of investigators, and lacking of objective criterion for sperm cell quality remains a problem. There is an ongoing debate on which criteria should be employed to define normal spermatozoa. Here, the aim of our ...

journal_title：Journal of biophotonics

authors： Huang Z,Chen G,Chen X,Wang J,Chen J,Lu P,Chen R

更新日期：2014-09-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a wide range of survival times. We aimed to explore prognostic factors related to short survival based on clinical features and plasma metabolic signatures using surface-enhanced Raman spectroscopy (SERS). One hundred and thirty-eight sporad...

journal_title：Journal of biophotonics

authors： Zhang QJ,Chen Y,Zou XH,Hu W,Lin XL,Feng SY,Chen F,Xu LQ,Chen WJ,Wang N

更新日期：2019-08-01 00:00:00

abstract：:The structural organization of cellular membranes has an essential influence on their functionality. The membrane surfaces currently are considered to consist of various distinct patches, which play an important role in many processes, however, not all parameters such as size and distribution are fully determined. In ...

journal_title：Journal of biophotonics

authors： Deckert-Gaudig T,Böhme R,Freier E,Sebesta A,Merkendorf T,Popp J,Gerwert K,Deckert V

更新日期：2012-07-01 00:00:00

abstract：:Photodynamic therapy (PDT) uses photosensitizers and visible light in combination with molecular oxygen to produce reactive oxygen species (ROS) that kill malignant cells by apoptosis and/or necrosis, shut down the tumor microvasculature and stimulate the host immune system. The excited singlet state of oxygen (1 O2 )...

journal_title：Journal of biophotonics

authors： Li B,Lin L,Lin H,Wilson BC

更新日期：2016-12-01 00:00:00