Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency.

abstract：OBJECTIVE:The coexistence of celiac disease (CeD) and eosinophilic esophagitis (EoE) in pediatric patients has been increasingly recognized. In the current study, we have aimed to assess the outcomes of therapeutic dietary interventions in a cohort of pediatric patients with CeD and EoE. METHODS:Pediatric patient reco...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Patton T,Chugh A,Padhye L,DeGeeter C,Guandalini S

更新日期：2019-08-01 00:00:00

abstract：:The clinical efficacy of twice-daily cimetidine (20 mg/kg/day) was retrospectively studied in 19 children with gastric ulcer (GU) and 23 with duodenal ulcer (DU) in the active stage. Endoscopically confirmed cumulative healing rates at 2, 4, and 8 weeks of treatment were 53.5, 73.7, and 94.7% in the GU group and 15.4,...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kato S,Ozawa A,Shibuya H,Ohtake M,Nakagawa H

更新日期：1994-04-01 00:00:00

abstract：:Human breast milk contains many enzymes, some of which may assist in digestion; other enzymes may have other diverse functions. The loci and regulation of milk enzyme synthesis remain to be elucidated, but multiple loci and complex hormonal regulation seem to be likely. In a similar fashion, multiple mechanisms of pro...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Heitlinger LA

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVES:We aimed to identify early noninvasive predictors of clinical and endoscopic remission in children with Crohn disease (CD) under infliximab (IFX). METHODS:Prospective observational study conducted in children with moderate-to-severe CD starting IFX. All patients underwent weighted pediatric CD activity inde...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： D'Arcangelo G,Oliva S,Dilillo A,Viola F,Civitelli F,Isoldi S,Cucchiara S,Aloi M

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To determine the natural history of treated and untreated eosinophilic esophagitis (EE) and examine the presenting symptoms of EE. PATIENTS AND METHODS:Retrospective and prospective chart review of all patients diagnosed with EE at The Children's Hospital of Philadelphia. EE was defined as greater than 20 eo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Spergel JM,Brown-Whitehorn TF,Beausoleil JL,Franciosi J,Shuker M,Verma R,Liacouras CA

更新日期：2009-01-01 00:00:00

abstract：:The underlying causes of chronic diarrhea beginning early in life are increasingly well defined. Infectious and post-infectious enteropathies and food sensitive/allergic enteropathy account for the majority of cases. Recent attention has focused on characterizing defined entities, which cause protracted diarrhea in in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sherman PM,Mitchell DJ,Cutz E

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:The present study aims to identify the genotype-phenotype correlation in children with Peutz-Jeghers Syndrome (PJS) through the analysis of STK11 gene mutations in the context of clinical and pathological characteristics. METHOD:In this observational cohort study, the clinical characteristics of 18 families...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zhao HM,Yang YJ,Duan JQ,Ouyang HJ,Liu L,Yi LC,Xiao ZH,Zheng Y,Peng L,Attard TM,Li DY,You JY

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Starch is an important source of energy for children with cystic fibrosis, but little is known about their capacity to digest it. METHODS:A 13C breath test was used to measure starch digestion and oxidation in 16 children with cystic fibrosis (median [range] age, 7.9 [4-15] years; 7 girls, 9 boys) and 5 nor...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Amarri S,Harding M,Coward WA,Evans TJ,Weaver LT

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:We prospectively evaluated incidence of prolonged (>28 days) parenteral nutrition (PN), associated complications, and significance of parenteral plant sterols (PS) in neonatal intestinal failure-associated liver disease (IFALD) compared with children. METHODS:We recruited 28 neonates (mean age 50 days, rang...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kurvinen A,Nissinen MJ,Andersson S,Korhonen P,Ruuska T,Taimisto M,Kalliomäki M,Lehtonen L,Sankilampi U,Arikoski P,Saarela T,Miettinen TA,Gylling H,Pakarinen MP

更新日期：2012-06-01 00:00:00

abstract：:Proton pump inhibitors such as lansoprazole are used in the treatment of gastroesophageal reflux disease (GERD), but dosing guidelines for infants have not been determined. The objective of this study was to assess the clinical efficacy of 2 dosing regimens of lansoprazole in infants with GERD using the revised infant...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Dhume P

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:Lutein and zeaxanthin are dietary carotenoids that may influence visual and cognitive development. The objective of this study was to provide the first data on distribution of carotenoids in the infant brain and compare concentrations in preterm and term infants. METHODS:Voluntarily donated brain tissues fr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vishwanathan R,Kuchan MJ,Sen S,Johnson EJ

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Gastroesophageal reflux is common but remains a controversial disease to diagnose and treat and little is known about the role of reflux testing in predicting clinical outcomes, particularly in children at risk for extraesophageal reflux complications. The aim of this study was to determine if rates of hospi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Duncan DR,Amirault J,Johnston N,Mitchell P,Larson K,Rosen RL

更新日期：2016-08-01 00:00:00

abstract：:The incidence of inflammatory bowel disease (IBD) is steadily on the rise in Western and in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. Furthermore, nutrition is involved in several aspects ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shaoul R,Brown S,Day AS

更新日期：2018-03-01 00:00:00

abstract：:Serum carboxyterminal propeptide of type I procollagen (PICP) and cross-linked carboxyterminal telopeptide of type I collagen (ICTP), new markers of bone collagen type I biosynthesis and degradation, have not been studied in small for gestational age (SGA) infants. In an earlier study, we found a lower bone mineral co...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Namgung R,Tsang RC,Sierra RI,Ho ML

更新日期：1996-10-01 00:00:00

abstract：:R-1 anti-reticulin antibodies (ARA) were present in sera of 10 of the 12 children who subsequently fulfilled the ESPGAN diagnostic criteria for celiac disease (CD), but was not found in any children in the age-matched control groups, viz., severely malnourished (n = 20), acute gastroenteritis (n = 23), normally nouris...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Bhan MK,Unsworth DJ,Kumar R,Walker Smith JA

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Premature infants receiving alimentation with cow milk-based formulas run a considerably high risk of incipient late metabolic acidosis, an early stage developing of manifest late metabolic acidosis. Is bone metabolism involved in pathophysiologic mechanisms characterizing this early stage of retention acido...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kalhoff H,Diekmann L,Rudloff S,Manz F

更新日期：2001-11-01 00:00:00

abstract：:A report on a case of rickets in a very low birth weight infant (VLBWI) is presented. The infant had no high-risk factors for rickets and was fed a specialized preterm formula with vitamin D supplementation (200 IU daily) by 10 days of age. Feeds were advanced so that an enteral intake of 120 cal/kg/day was achieved b...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cooke RJ

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVES:Eosinophilic esophagitis (EoE) can present as food selectivity or feeding disorders in children. Children with autism spectrum disorders (ASDs) commonly demonstrate behavioral food selectivity in type and texture, which often leads to the diagnosis of feeding disorder. We sought to evaluate the association o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Heifert TA,Susi A,Hisle-Gorman E,Erdie-Lalena CR,Gorman G,Min SB,Nylund CM

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Inflammatory bowel disease (IBD) is a chronic lifelong condition and is related to poor quality of life (QoL). The aim of this study was to evaluate the QoL of Asian pediatric patients with IBD and to determine the clinical factors that can influence QoL. METHODS:Children and adolescents aged 9 to 18 years ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kim S,Park S,Kang Y,Kim JE,Kang B,Choe BH,Lee YJ,Park JH,Yang HR,Lee SH,Kim KM,Ryoo E,Tchah H,Shim JO,Koh H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the in vitro effects of sera from children with acute liver failure (ALF) who had received N-acetylcysteine (NAC) on the metabolic and synthetic activity of cryopreserved human hepatocytes. MATERIALS AND METHODS:Cryopreserved human hepatocytes were plated on collagen-c...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mitry RR,Bansal S,Hughes RD,Mieli-Vergani G,Dhawan A

更新日期：2009-05-01 00:00:00

abstract：:Ventriculoperitoneal shunts are currently a standard therapy for obstructive hydrocephalus. These shunts are associated with a variety of abdominal complications, one of which is the development of ascites. We report an 11-year-old girl with a ventriculoperitoneal shunt in whom a low-grade peritoneal infection present...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Goodman GM,Gourley GR

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the incidence of peptic ulcer bleeding (PUB) in pediatric patients. METHODS:A hospital inpatient database, Premier Perspective, and an insurance claims database, MarketScan, were analyzed to estimate upper and lower limits for the annual incidence of PUB in the ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Brown K,Lundborg P,Levinson J,Yang H

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not bee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ariff S,Krebs NF,Westcott JE,Hambidge M,Miller LV,Rizvi A,Soofi SB,Bhutta ZA

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:A previously unrecognized high prevalence of celiac disease (CD) has been found by screening among European and North American patients with type 1 diabetes mellitus (DM 1). The prevalence of CD among Brazilian children with DM1 is not known. This study was conducted to determine the prevalence of CD in Brazi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Baptista ML,Koda YK,Mitsunori R,Nisihara,Ioshii SO

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to evaluate whether polymorphisms of the mannose-binding lectin (MBL-2) gene and MBL serum levels on admission to neonatal intensive care unit are associated with necrotizing enterocolitis (NEC) in preterm infants and to verify MBL expression in NEC bowels. METHODS:In this r...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Prencipe G,Azzari C,Moriondo M,Devito R,Inglese R,Pezzullo M,Piersigilli F,Trucchi A,De Benedetti F,Auriti C

更新日期：2012-08-01 00:00:00

abstract：:The effect of a lipid emulsion containing long-chain triglycerides (LCT) and supplemented with L-carnitine on plasma lipids and bilirubin in premature neonates on total parenteral nutrition was compared to that of lipid emulsions containing either LCT or a mixture of LCT and medium-chain triglycerides (MCT). In a doub...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rubin M,Naor N,Sirota L,Moser A,Pakula R,Harell D,Sulkes J,Davidson S,Lichtenberg D

更新日期：1995-07-01 00:00:00

abstract：:Twenty children with active ulcerative colitis were assessed before and after 8 weeks of medical therapy with 5-aminosalicylic acid (5-ASA) derivatives and corticosteroids. Local therapy was given for distal disease (seven cases); other disease was treated with oral prednisolone (1-2 mg/kg/day, maximum 40 mg). Eightee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Beattie RM,Nicholls SW,Domizio P,Williams CB,Walker-Smith JA

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the safety of lansoprazole in children between 1 and 11 years of age. METHODS:In a phase I/II, open-label, multicenter (11 sites) study, children with symptomatic gastroesophageal reflux disease (GERD), erosive esophagitis (> or = grade 2), and/or esophageal pH < 4 for > 4.2% of the 24-hour peri...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tolia V,Fitzgerald J,Hassall E,Huang B,Pilmer B,Kane R 3rd

更新日期：2002-01-01 00:00:00

abstract：:The nutritional management of intractable diarrhea and short bowel syndrome remains a challenging problem. The advantage of continuous nasogastric infusion is undisputed, but what to feed remains in question, and no studies, to these authors' knowledge, have yet compared two widely used specially designed protein hydr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Galeano NF,Lepage G,Leroy C,Belli D,Levy E,Roy CC

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:Liver nodularity occurs across the spectrum of cystic fibrosis liver disease (CFLD), from regenerative nodules to cirrhosis, and can occur without liver enzyme abnormalities. Our aims were to determine if incorporating abdominal ultrasound (US) with annual laboratory testing improves the detection of CFLD an...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sellers ZM,Lee LW,Barth RA,Milla C

更新日期：2019-10-01 00:00:00