Normal serum indices of bone collagen biosynthesis and degradation in small for gestational age infants.

Abstract:

:Serum carboxyterminal propeptide of type I procollagen (PICP) and cross-linked carboxyterminal telopeptide of type I collagen (ICTP), new markers of bone collagen type I biosynthesis and degradation, have not been studied in small for gestational age (SGA) infants. In an earlier study, we found a lower bone mineral content (BMC) and decreased serum osteocalcin in SGA than in appropriate for gestational age (AGA) infants, supporting the thesis that decreased fetal bone formation is a cause of lower BMC in SGA. In view of the role of insulin-like growth factor-I (IGF-I) in the regulation of collagen type I synthesis and degradation, and low serum IGF-I concentrations in SGA infants, we hypothesized that serum PICP would be lower and serum ICTP would be higher in SGA than in AGA infants, reflecting decreased bone collagen type I biosynthesis or enhancement of bone collagen type I degradation in SGA. We studied 19 term SGA and 38 term AGA infants that were matched specifically 1:2 by gestation and birth month. There were no differences between SGA and AGA infants in serum PICP nor ICTP concentrations. Serum ICTP was correlated with osteocalcin and with PICP in SGA infants but not in AGA infants. Thus, serum biochemical indices of bone collagen type I biosynthesis and degradation in term SGA infants are similar to those in term AGA infants. These findings are not consistent with the thesis of altered fetal bone collagen type I biosynthesis or degradation in SGA. We suggest that the reduced bone mineral content in SGA infants is predominantly related to a lower supply of minerals rather than defective regulation of bone collagen type I metabolism.

authors

Namgung R,Tsang RC,Sierra RI,Ho ML

doi

10.1097/00005176-199610000-00004

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

224-8

issue

3

eissn

0277-2116

issn

1536-4801

journal_volume

23

pub_type

杂志文章
  • Role of small bowel follow-through in diagnosing inflammation of the terminal ileum in pediatric patients.

    abstract:BACKGROUND:The small bowel follow-through (SBFT) is a noninvasive imaging modality for evaluating terminal ileum (TI) inflammation. The accuracy of this modality in pediatric patients is not well established. PATIENTS AND METHODS:We retrospectively determined the sensitivity and specificity of SBFT for detecting TI in...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3181d67ea7

    authors: Stenerson M,Vittinghoff E,Heyman MB,Kim GE,Gupta N

    更新日期:2010-10-01 00:00:00

  • Management of Juvenile Polyposis Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group.

    abstract::The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Polyposis Working Group developed recommendations to assist clinicians and health care providers with appropriate management of patients with juvenile polyposis. This is the first juvenile polyposis Position Paper published by ESP...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,评审

    doi:10.1097/MPG.0000000000002246

    authors: Cohen S,Hyer W,Mas E,Auth M,Attard TM,Spalinger J,Latchford A,Durno C

    更新日期:2019-03-01 00:00:00

  • Evaluation of oral rehydration solution by whole-gut perfusion in rats: effect of osmolarity, sodium concentration and resistant starch.

    abstract:BACKGROUND:Reduced osmolarity oral rehydration solution (ORS) improved small bowel absorption of fluid and electrolytes in segmental perfusion in experimental animals; this was borne out in clinical practice. Adding amylase-resistant starch (RS) to ORS is expected to increase colonic fluid absorption. This study used c...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/01.mpg.0000239998.43141.b2

    authors: Subramanya S,Ramakrishna BS,Binder HJ,Farthing MJ,Young GP

    更新日期:2006-11-01 00:00:00

  • Lactobacillus plantarum inhibits the intestinal epithelial migration of neutrophils induced by enteropathogenic Escherichia coli.

    abstract:BACKGROUND:Lactobacillus plantarum is a Gram-positive bacillus known for its effect as a probiotic agent. The goal of the study was to determine whether L. plantarum is capable of inhibiting the transepithelial neutrophil migration induced by enteropathogenic Escherichia coli (EPEC). METHODS:Cultured intestinal epithe...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-200303000-00017

    authors: Michail S,Abernathy F

    更新日期:2003-03-01 00:00:00

  • Rotavirus A Infections in Community Childhood Diarrhea in the Brazilian Semiarid Region During Postvaccination Era.

    abstract:BACKGROUND:Rotavirus A (RVA) is one of the leading causes of acute gastroenteritis worldwide; however, few studies assessed RVA genetics with community surveillance. OBJECTIVES:This study aimed to investigate clinical data, genetic diversity, and coinfection patterns of RVA infections in children from 2 to 36 months o...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000002416

    authors: Pankov RC,Gondim RNDG,Prata MMG,Medeiros PHQS,Veras HN,Santos AKS,Havt A,da Silva MFM,Fumian TM,Miagostovich MP,Leite JPG,Lima AAM

    更新日期:2019-10-01 00:00:00

  • Comparison of oral sodium phosphate to polyethylene glycol-based solution for bowel preparation for colonoscopy in children.

    abstract::Thirty-four patients, aged 3 to 17 years, were randomized to receive oral sodium phosphate solution or a polyethylene glycol-based solution in preparation for elective colonoscopy. Nineteen patients received two doses of oral sodium phosphate solution (45 mL/1.7 m2/ dose) and 15 received polyethylene glycol-based solu...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00005176-199612000-00013

    authors: Gremse DA,Sacks AI,Raines S

    更新日期:1996-12-01 00:00:00

  • Use of a real-time viewer for endoscopic deployment of capsule endoscope in the pediatric population.

    abstract:OBJECTIVES:Wireless capsule endoscopy (WCE) is an increasingly used procedure for visualization of the small intestine. One challenge in pediatric WCE is the placement of the capsule in a population unable to swallow it for a variety of reasons. Here we present a novel use of the real-time (RT) viewer in the endoscopic...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e318261879d

    authors: Bass LM,Misiewicz L

    更新日期:2012-11-01 00:00:00

  • Obesity Does Not Affect Early Outcomes in Children With Newly Diagnosed Crohn Disease.

    abstract::The impact of obesity on pediatric Crohn disease (CD) remains poorly characterized. We aimed to evaluate disease-related outcomes in overweight and obese children with CD, compared to normal-weight children. We conducted a retrospective cohort study of children with newly diagnosed CD enrolled in the ImproveCareNow Ne...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000002066

    authors: Jain A,Bricker J,Kappelman MD,Dotson JL

    更新日期:2018-11-01 00:00:00

  • The complexity of feeding problems in 700 infants and young children presenting to a tertiary care institution.

    abstract:BACKGROUND:Feeding problems are common in infants and young children. A multidisciplinary team approach contributes to better patient care. However, few quantitative data on multidisciplinary feeding assessment of children have been published. OBJECTIVES The first aim of this study was to characterize the etiology of f...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-200307000-00014

    authors: Rommel N,De Meyer AM,Feenstra L,Veereman-Wauters G

    更新日期:2003-07-01 00:00:00

  • Serum IgA and IgG gliadin antibodies and small intestinal mucosal damage in children.

    abstract::Serum immunoglobulin (Ig) A and IgG gliadin antibodies were determined with a simple, rapid, and inexpensive method--diffusion-in-gel enzyme-linked immunosorbent assay (DIG-ELISA)--and the results were related to small intestinal mucosal morphology in 234 children suspected of having malabsorption. Fifty-six of 58 chi...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198512000-00011

    authors: Lindberg T,Nilsson LA,Borulf S,Cavell B,Fällström SP,Jansson U,Stenhammar L,Stintzing G

    更新日期:1985-12-01 00:00:00

  • Alkaline phosphatase activity in fresh intestinal mucosa and cultured mucosal explants.

    abstract::Alkaline phosphatase (AP) activity is an accepted marker of epithelial cell differentiation and integrity in intestinal mucosal explant systems. In experiments involving AP it is usually expressed as activity per unit protein in tissue culture. It has been previously demonstrated that during organ culture a considerab...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198403000-00007

    authors: Ashkenazi A,Idar D,Maimon M,Hegesh E,Frank E,Hahn T,Wolman Y,Levin S

    更新日期:1984-03-01 00:00:00

  • Reasoning Beyond the Potential Use of Exclusive Enteral Nutrition and Other Specified Diets in Children With Ulcerative Colitis.

    abstract::The incidence of inflammatory bowel disease (IBD) is steadily on the rise in Western and in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. Furthermore, nutrition is involved in several aspects ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,评审

    doi:10.1097/MPG.0000000000001785

    authors: Shaoul R,Brown S,Day AS

    更新日期:2018-03-01 00:00:00

  • Effects of oral administration of bifidobacterium breve on fecal lactic acid and short-chain fatty acids in low birth weight infants.

    abstract:OBJECTIVES:Short-chain fatty acids (SCFAs) are known to provide energy to colonocytes, whereas overproduction of SCFAs can cause mucosal injury in premature infants. Our objective was to investigate the effects of the oral administration of Bifidobacterium breve M-16V (B breve) on fecal lactic acid and SCFAs in low bir...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/01.mpg.0000252184.89922.5f

    authors: Wang C,Shoji H,Sato H,Nagata S,Ohtsuka Y,Shimizu T,Yamashiro Y

    更新日期:2007-02-01 00:00:00

  • Enhancements in Confidence, Acceptance, and Friendship at a Summer Camp for Children With Inflammatory Bowel Disease.

    abstract::Inflammatory bowel disease (IBD) affects many children and adolescents in terms of their confidence, acceptance, and ability to build friendships. New Zealand held its first summer camp for children with IBD in January 2015. We obtained feedback from the campers (ages 10-18 years) in terms of their confidence, accepta...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000001526

    authors: McCombie A,Gearry RB,Lopez RN,Lönnfors S,Day AS

    更新日期:2017-09-01 00:00:00

  • Prevention of rotavirus-induced diarrhea by preferential secretion of IgA in breast milk via maternal administration of Lactobacillus gasseri SBT2055.

    abstract:OBJECTIVES:Rotavirus (RV)-induced diarrhea poses a major health problem, particularly to infants. An effective measure to prevent RV infection is to consume breast milk with higher levels of protective IgA. We therefore examined whether Lactobacillus gasseri SBT2055 (LG2055) could augment immunoglobulin (Ig) A levels a...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3182533a2b

    authors: Kadooka Y,Tominari K,Sakai F,Yasui H

    更新日期:2012-07-01 00:00:00

  • Vitamin A concentration in the liver decreases with age in patients with cystic fibrosis.

    abstract:BACKGROUND:Vitamin A deficiency is a common manifestation in cystic fibrosis (CF), but high levels of vitamin A in the liver have also been described. High levels of vitamin A in the liver are toxic, while normal levels might be protective against liver damage. In order to investigate whether liver damage in patients w...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-199703000-00006

    authors: Lindblad A,Diczfalusy U,Hultcrantz R,Thorell A,Strandvik B

    更新日期:1997-03-01 00:00:00

  • Contamination of gastrostomy feeding systems in children in a home-based enteral nutrition program.

    abstract:BACKGROUND:There are few data concerning the risk of contamination of enteral feeding systems via gastrostomy in children, and none for conditions that pertain to home-based care. METHODS:To investigate the risk of contamination of enteral feeding systems during the home-based care of 20 children receiving gastrostomy...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-200109000-00007

    authors: Bott L,Husson MO,Guimber D,Michaud L,Arnaud-Battandier F,Turck D,Gottrand F

    更新日期:2001-09-01 00:00:00

  • Reduced bile output with chronic enteral and parenteral infusion of amino acids, glucose, and fat emulsion in rabbits.

    abstract::To assess the effect of chronic administration of amino acids, glucose, and fat on hepatic excretory function, bile flow and bile salt secretion were directly measured in adult rabbits alimented either intravenously or intragastrically. Five groups of animals were studied after 9-11 days on different nutritional regim...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198510000-00023

    authors: Zahavi I,Shaffer EA,Kelly J,Gall DG

    更新日期:1985-10-01 00:00:00

  • Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis.

    abstract:BACKGROUND:An increased incidence of necrotizing enterocolitis (NEC) has been noted in infants who are born to mothers with chorioamnionitis. HYPOTHESIS:Our objective was to test the hypothesis that newborn rat pups born to mothers exposed to prenatal lipopolysaccharide during pregnancy would be more susceptible to in...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/mpg.0b013e31818936b8

    authors: Giannone PJ,Nankervis CA,Richter JM,Schanbacher BL,Reber KM

    更新日期:2009-03-01 00:00:00

  • Baclofen for the treatment of pediatric GERD.

    abstract:BACKGROUND AND AIM:Baclofen, a γ-aminobutyric acid receptor agonist, has been shown to reduce the episodes of gastroesophageal reflux (GER) by reducing the incidence of transient lower esophageal sphincter relaxations. Although baclofen has been shown to reduce reflux symptoms in adults, data in pediatric patients are ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3182a2747b

    authors: Vadlamudi NB,Hitch MC,Dimmitt RA,Thame KA

    更新日期:2013-12-01 00:00:00

  • Clear Liquid Versus Low-fibre Diet in Bowel Cleansing for Colonoscopy in Children: A Randomized Trial.

    abstract:OBJECTIVES:In light of a paucity of data on the role of diet in colonoscopy preparation in paediatric population, the present study was designed to compare the effectiveness of clear liquid and low-fibre diets for breakfast and lunch on the day preceding colonoscopy in children. METHODS:This prospective, randomised tr...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MPG.0000000000001832

    authors: Mytyk A,Lazowska-Przeorek I,Karolewska-Bochenek K,Kakol D,Banasiuk M,Walkowiak J,Albrecht P,Banaszkiewicz A

    更新日期:2018-05-01 00:00:00

  • Fibrin glue application in the management of refractory chylous ascites in children.

    abstract::The purpose of this retrospective review of the charts of 6 children who underwent surgical treatment of chylous ascites refractory to conservative measures between 1993 and 2006 was to evaluate the efficiency of fibrin glue application for control of lymph leakage. Five children had postoperative chylous ascites (neu...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e31815ce5be

    authors: Zeidan S,Delarue A,Rome A,Roquelaure B

    更新日期:2008-04-01 00:00:00

  • Sensory Processing Difficulties in Toddlers With Nonorganic Failure-to-Thrive and Feeding Problems.

    abstract:OBJECTIVES:Failure-to-thrive is defined as an abnormally low weight and/or height for age. The term "nonorganic failure-to-thrive" (NOFT) has been used to describe "failure-to-thrive" without an obvious cause underlying the growth failure. The purpose of the present study was to compare sensory processing abilities bet...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000000707

    authors: Yi SH,Joung YS,Choe YH,Kim EH,Kwon JY

    更新日期:2015-06-01 00:00:00

  • Early Obesity: Risk Factor for Fatty Liver Disease.

    abstract::Nonalcoholic fatty liver disease (NAFLD), defined as fat accumulation greater than 5% in hepatocytes, may progress to fibrosis or cirrhosis later in life. NAFLD prevalence in adolescents has increased significantly in direct relation with obesity prevalence. Fatty liver has become the most frequent indication for live...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000002523

    authors: Cuzmar V,Alberti G,Uauy R,Pereira A,García C,De Barbieri F,Corvalán C,Santos JL,Mericq V,Villarroel L,Gana JC

    更新日期:2020-01-01 00:00:00

  • Cow's-milk allergy is a risk factor for the development of FGIDs in children.

    abstract:OBJECTIVES:Functional gastrointestinal disorders (FGIDs) are common in children. Their pathogenesis remains unknown and is most likely multifactorial. We hypothesized that noninfectious causes of inflammation affecting the gastrointestinal (GI) tract early in life, such as cow's-milk allergy (CMA), can predispose to th...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3181e85b55

    authors: Saps M,Lu P,Bonilla S

    更新日期:2011-02-01 00:00:00

  • Crying does not exacerbate gastroesophageal reflux in infants.

    abstract::The behavior and intraluminal esophageal pH of 48 infants (5-26 weeks old) were continuously recorded during the 120-min period following their ingestion of a standard volume of apple juice (pH approximately 4). To evaluate the effect of three basic behavior states on the frequency of infant gastroesophageal reflux, t...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-199201000-00007

    authors: Orenstein SR

    更新日期:1992-01-01 00:00:00

  • A metabolic bed for collecting excreta in premature infants.

    abstract::A mattress and plastic bed for collection of urine and feces in premature infants housed in isolettes is described. The dimensions of the bed are 65.5 x 34.4 x 13.5 cm. A drainage hole is located 18 cm from the foot of the bed and midway (16.5 cm) from either side. The angle of the depression in the bed for the draina...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-199005000-00011

    authors: Kien CL

    更新日期:1990-05-01 00:00:00

  • Ferric Carboxymaltose Across all Ages in Paediatric Gastroenterology Shows Efficacy Without Increased Safety Concerns.

    abstract:OBJECTIVES:To assess the efficacy, safety and side-effect profile of ferric carboxymaltose (FCM) for correcting IDA in children and adolescents in paediatric gastroenterology, hepatology and nutrition. METHOD:This was a retrospective study of all gastroenterology patients <18years who had FCM (October 2015 to October ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000003003

    authors: Sasankan N,Duncan H,Curtis L,McGuckin C,Shannon C,Barclay A,Fraser S,Nair M,Russell RK,Hansen R

    更新日期:2020-11-20 00:00:00

  • Prolonged enteral feeding is often required to avoid long-term nutritional and metabolic complications after esophagogastric dissociation.

    abstract:BACKGROUND:Total esophagogastric dissociation (TED) was first described in 1997 by Bianchi as a new surgical procedure to treat severe gastroesophageal reflux disease (GERD) in children with neurological impairment. Recently, TED has been proposed in other conditions, such as esophageal atresia, esotracheal cleft, or c...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3181a159fa

    authors: Madre C,Serhal L,Michaud L,Bonnevalle M,de Lagausie P,Gottrand F,Bonnard A,Hugot JP

    更新日期:2010-03-01 00:00:00

  • Epithelial functions of the residual bowel after surgery for necrotising enterocolitis in human infants.

    abstract:OBJECTIVES:Information on epithelial functions of the residual small or colonic bowel after resection for necrotising enterocolitis (NEC) in human infants is scarce. Our aim is to evaluate epithelial functions in the intestinal resection margins of tissue obtained at bowel resection for acute NEC and consecutive stoma ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e318186d341

    authors: Schaart MW,de Bruijn AC,Bouwman DM,de Krijger RR,van Goudoever JB,Tibboel D,Renes IB

    更新日期:2009-07-01 00:00:00