Gastroesophageal Reflux Burden, Even in Children That Aspirate, Does Not Increase Pediatric Hospitalization.

abstract：OBJECTIVES:Assessment of intra- and interobserver agreement in multiple intraluminal impedance (MII) measurement between investigators from different institutions. METHODS:Twenty-four 18- to 24-hour MII tracings were randomly chosen from 4 different institutions (6 per center). Software-aided automatic analysis was pe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pilic D,Höfs C,Weitmann S,Nöh F,Fröhlich T,Skopnik H,Köhler H,Wenzl TG,Schmidt-Choudhury A

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:Data on the outcomes of children with perianal Crohn disease (pCD) are limited, although its presence is often used for justifying early use of biologics. We aimed to assess whether pCD in children is associated with more severe outcomes as found in adults. METHODS:Data were extracted from the ImageKids dat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Assa A,Amitai M,Greer ML,Castro DA,Kuint RC,Martínez-León M,Herman-Sucharska I,Coppenrath E,Anupindi S,Towbin A,Moote D,Konen O,Pratt LT,Griffiths A,Turner D,ImageKids Study Group.

更新日期：2017-09-01 00:00:00

abstract：:In this prospective study, neonates with clinical congenital syphilis were investigated to determine if penicillin therapy caused a deterioration in liver function. The relationship between circulating immune complexes and liver involvement was monitored, and the efficacy of steroid therapy as an adjunct in the treatm...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Venter A,Pettifor JM,Duursma J,Pudifin DJ,Smyth A,Becker PJ

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Vedolizumab (VDZ) is effective for treating both adult and pediatric onset inflammatory bowel disease (IBD). Clinical outcomes, however, have been reported to be superior in patients naïve to anti-tumor necrosis factor (TNF). With the growing interest in endoscopic endpoints, we aimed to describe rates of mu...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jossen J,Kiernan BD,Pittman N,Dubinsky MC

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Differentiation of Crohn disease (CD) from ulcerative colitis (UC) is challenging when inflammation is predominantly colonic. The paediatric inflammatory bowel disease (PIBD) classes algorithm was developed to bring consistency to labelling, but used physician-assigned diagnosis as the criterion standard. We...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dhaliwal J,Siddiqui I,Muir J,Rinawi F,Church PC,Walters TD,Griffiths AM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Tissue transglutaminase (tTG) autoantibodies are serologic markers for celiac disease (CD). The aim was to determine the diagnostic sensitivity and specificity of different immunoglobulin isotypes against tTG. METHODS:Immunoglobulin A (IgA)-tTG, IgG-tTG, and IgG1-tTG were measured in radioligand binding ass...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Agardh D,Borulf S,Lernmark A,Ivarsson SA

更新日期：2003-01-01 00:00:00

abstract：:Serum immunoglobulin (Ig) A and IgG gliadin antibodies were determined with a simple, rapid, and inexpensive method--diffusion-in-gel enzyme-linked immunosorbent assay (DIG-ELISA)--and the results were related to small intestinal mucosal morphology in 234 children suspected of having malabsorption. Fifty-six of 58 chi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lindberg T,Nilsson LA,Borulf S,Cavell B,Fällström SP,Jansson U,Stenhammar L,Stintzing G

更新日期：1985-12-01 00:00:00

abstract：:We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patien...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Schoepfer AM,Vavricka S,Safroneeva E,Fournier N,Manser C,Frei P,Deltenre P,Rogler G,Straumann A,Ezri J,Nydegger A,Braegger C

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the effect of autoimmune hepatitis (AIH) on the quality of life of children and adolescents and to identify which variables effect health-related quality of life (HRQoL). METHODS:The Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) was used to evaluate HRQoL. In add...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Trevizoli IC,Pinedo CS,Teles VO,Seixas RBPM,de Carvalho E

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:We prospectively studied children with portal hypertension (PHT) for portal hypertensive duodenopathy (PHTD) and small bowel intestinal permeability (SIP) with the objectives of defining histopathological parameters for PHTD and to find out whether any association existed among structural changes, SIP, and nu...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Borkar VV,Poddar U,Kumari N,Singh S,Roy R,Yachha SK

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:This position paper written by the Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition aimed to systematically evaluate clinical practice guidelines (CPGs), medical consensus, and position papers on the use of direct-acting antivirals (DA...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Indolfi G,Fischler B,Gonzalez-Peralta RP,Ciocca M,Porta G,Neelam M,El-Guindi M,Kelly D,Ni YH,Sibal A,Leung DH,Chang MH,Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology,

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:On the basis of studies with hepatorenal syndrome, it is widely regarded that renal function is impacted in chronic liver disease (CLD). Therefore, we investigated renal function in children with CLD. METHODS:In a retrospective study of 277 children with CLD, renal function was investigated as glomerular fi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Berg UB,Németh A

更新日期：2018-04-01 00:00:00

abstract：:Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated wit...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hall CHT,Nguyen N,Furuta GT,Prager J,Deboer E,Deterding R,Menard-Katcher C,Capocelli KE,Kramer RE,Friedlander JA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to design a theory-based educational program for adolescents with inflammatory bowel disease (IBD) using an interactive multimedia CD-ROM and to test its effectiveness in improving knowledge in IBD. MATERIALS AND METHODS:Curriculum-based instruction using educational theory and prin...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Boamah LM,Bohren JR,Pentiuk S,Baker R,Yi M,Moyer MS

更新日期：2010-05-01 00:00:00

abstract：:Enteral nutrition support (ENS) involves both the delivery of nutrients via feeding tubes and the provision of specialised oral nutritional supplements. ENS is indicated in a patient with at least a partially functioning digestive tract when oral intake is inadequate or intake of normal food is inappropriate to meet t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Braegger C,Decsi T,Dias JA,Hartman C,Kolacek S,Koletzko B,Koletzko S,Mihatsch W,Moreno L,Puntis J,Shamir R,Szajewska H,Turck D,van Goudoever J,ESPGHAN Committee on Nutrition:.

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Shwachman's syndrome is the second most common cause of inherited/congenital pancreatic insufficiency after cystic fibrosis. The main associated features are usually cyclic neutropenia, metaphyseal dysostosis, and growth retardation. Other organs or functions may be involved in this syndrome, showing a wide ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cipolli M,D'Orazio C,Delmarco A,Marchesini C,Miano A,Mastella G

更新日期：1999-09-01 00:00:00

abstract：:The general goals of treatment of cyclic vomiting syndrome (CVS) are: interruption of established episodes, amelioration of symptoms in patients whose episodes cannot be interrupted, aborting episodes during prodromal symptoms, prophylaxis to abolish or lessen the frequency of episodes, and recovery. Complications of ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fleisher DR

更新日期：1995-01-01 00:00:00

abstract：:BE is a disorder that occurs in children likely as a consequence of prolonged GE reflux of gastroduodenal contents. It usually presents with complications of GE reflux, but it also may be relatively silent in childhood and then present with adenocarcinoma in childhood or present in adulthood. Although seldom recognize...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hassall E

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Although perianal complications of Crohn disease (CD) are commonly encountered in clinical practice, the epidemiology of perianal CD among populations of children is poorly understood. We sought to characterize the prevalence of perianal disease in a large and diverse population of pediatric patients with CD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Adler J,Dong S,Eder SJ,Dombkowski KJ,ImproveCareNow Pediatric IBD Learning Health System.

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide hormone released from enteroendocrine L-cells following nutrient ingestion. It has been shown to exert trophic effects on the gut. We set out to measure GLP-2 concentrations in blood in children with diarrhoea and malnutrition. METHODS:GLP-2 levels ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Besa EC,Chandwe K,Banda R,Munalula L,Kalomo L,Amadi B,Kelly P

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Polyethylene glycol (PEG) is a frequently used laxative agent. It is unknown, however, whether PEG affects the absorptive capacity of the intestine. Reduced lipid (dietary fat and cholesterol) absorption induced by long-term PEG treatment could negatively affect growth in children. We tested whether PEG acce...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van der Wulp MY,Cuperus FJ,Stellaard F,van Dijk TH,Dekker J,Rings EH,Groen AK,Verkade HJ

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:It is presently recommended that oral feeding be started in premature infants as soon as possible, often at an age at which nasal continuous positive airway pressure (nCPAP) is still required for ventilatory support. Our previous data showed that application of nCPAP up to 10 cmH2O in full-term lambs had no ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Djeddi D,Cantin D,Samson N,Tian H,Praud JP

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the in vitro effects of sera from children with acute liver failure (ALF) who had received N-acetylcysteine (NAC) on the metabolic and synthetic activity of cryopreserved human hepatocytes. MATERIALS AND METHODS:Cryopreserved human hepatocytes were plated on collagen-c...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mitry RR,Bansal S,Hughes RD,Mieli-Vergani G,Dhawan A

更新日期：2009-05-01 00:00:00

abstract：:To explore the relationship between vitamin A deficiency and persistent diarrhea among young children, we studied the vitamin A status of 23 children greater than 5 years of age with persistent diarrhea by performing conjunctival impression cytology (CIC) and the relative dose-response test (RDR) as a measure of liver...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Usha N,Sankaranarayanan A,Walia BN,Ganguly NK

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:Loss of the complement inhibitor CD55 leads to a syndrome of early-onset protein-losing enteropathy (PLE), associated with intestinal lymphangiectasia and susceptibility to large-vein thrombosis. The in vitro and short-term treatment benefits of eculizumab (C5-inhibitor) therapy for CD55-deficiency have been...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kurolap A,Eshach Adiv O,Hershkovitz T,Tabib A,Karbian N,Paperna T,Mory A,Vachyan A,Slijper N,Steinberg R,Zohar Y,Mevorach D,Baris Feldman H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Intestinal failure (IF) is a common consequence of neonatal small bowel pathology. In our experience, bowel dilatation is often responsible for the IF state in patients who fail to adapt despite adequate residual bowel length. The aim of the present study was to investigate the role of surgery to reduce bowe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Almond SL,Haveliwala Z,Khalil B,Morabito A

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:In the present study, we studied a cohort of patients with very early onset inflammatory bowel disease (IBD) to determine the frequency of mutations in the interleukin 10 (IL10) receptor genes as a cause of early-onset IBD. METHODS:Sanger sequencing was performed to determine the presence of IL10 and/or IL1...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Beser OF,Conde CD,Serwas NK,Cokugras FC,Kutlu T,Boztug K,Erkan T

更新日期：2015-03-01 00:00:00

abstract：:Acarboxy prothrombin was detected in the plasma of 48 of 128 umbilical cord plasma samples and in all of 65 patients receiving coumadin. None was found in 20 normal adults. Although the prevalence was the same in blacks, whites, and neonates of mixed origin, levels were significantly higher in blacks. There was a nega...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Atkinson PM,Bradlow BA,Moulineaux JD,Walker NP

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of oropharyngeal colostrum administration in the incidence of late-onset clinical and proven sepsis and in concentrations of immunoglobulin A (IgA) in very-low-birth-weight (VLBW) infants. METHODS:We conducted a double-blinded, randomized, placebo-control...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ferreira DMLM,Oliveira AMM,de Leves DV,de Bem ÉB,Fatureto GG,Navarro NF,Afonso NG,Santiago FM,Mineo JR,Sopelete MC,Martinez FE,Bernardino Neto M,Abdallah VOS

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Ursodeoxycholic acid (UDCA) has been shown to improve pruritus, alanine aminotransferase (ALT), and cholesterol levels in children with intrahepatic cholestatic liver disease. However, the effect of UDCA on quantitative tests of hepatic function in children is uncertain. METHODS:A 2.5-year, open label, cros...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Narkewicz MR,Smith D,Gregory C,Lear JL,Osberg I,Sokol RJ

更新日期：1998-01-01 00:00:00