Futility: Definition and Goals.

abstract：:The term innovation is frequently used as a justification for allowing clinicians to offer unproven autologous stem cell-based interventions (SCBIs) to their patients. Proponents of this kind of innovation (which we refer to as "clinical innovation") argue that physicians should be free to administer whatever interven...

journal_title：Perspectives in biology and medicine

authors： Lipworth W,Stewart C,Kerridge I

更新日期：2018-01-01 00:00:00

abstract：:Metaphysics is an essential part of philosophy of medicine, providing the background for further methodological work. Current accounts of the ontology of particular diseases may be classified as realist or anti-realist. Because strong arguments can be marshaled by both of these positions, an approach to medical ontolo...

journal_title：Perspectives in biology and medicine

authors： Simon JR

更新日期：2008-07-01 00:00:00

abstract：:The impact of chronic illness on patients has been discussed extensively, but little attention has been paid to the reverse situation: the need for patients who have been chronically ill since childhood to adjust to health and normality in adulthood. Drawing upon the narratives of two adults with childhood onset disea...

journal_title：Perspectives in biology and medicine

authors： Orfali K,Anderson-Shaw L

更新日期：2005-04-01 00:00:00

abstract：:Since the beginning of the 21st century, the living conditions of undocumented migrant workers in Belgium have deteriorated drastically. In Brussels, after various social actions, undocumented people began squatting and occupying public buildings to make their struggle visible to society. Desperate, some seized the po...

journal_title：Perspectives in biology and medicine

authors： Vanobberghen R,Louckx F,Depoorter AM,Devroey D,Vandevoorde J

更新日期：2019-01-01 00:00:00

abstract：:The health aspects and benefits of conception control as a justification for U.S. government support of family planning are reviewed. The Family Planning Services Act of 1970 set a goal of serving 5 million indigent women by 1975. It is predicted that the program will far surpass that goal. 340 million dollars were...

journal_title：Perspectives in biology and medicine

authors： Hellman LM

更新日期：1973-04-01 00:00:00

abstract：:How we discovered that sea birds on the Great Barrier Reef are riddled with influenza viruses, and how one of these led to a new drug now being used in the battle against the flu. ...

journal_title：Perspectives in biology and medicine

authors： Laver WG

更新日期：2004-10-01 00:00:00

abstract：:During the 1970s, something deeply consequential happened in the cultural, economic, and social relationships between science and technology. Paul Forman has proposed that the abrupt reversal of the culturally ascribed primacy in the science-technology relationship circa 1980 be taken as a demarcation of postmodernity...

journal_title：Perspectives in biology and medicine

authors： Schweber SS

更新日期：2009-01-01 00:00:00

abstract：:How will developments in genetic knowledge affect the classification of disease? Leaders in genetics have suggested that knowledge of the role of genes in disease can determine nosology. Diseases might be defined by genotype, thus avoiding the limitations of more empirical approaches to categorization. Other commentat...

journal_title：Perspectives in biology and medicine

authors： Miller FA,Begbie ME,Giacomini M,Ahern C,Harvey EA

更新日期：2006-01-01 00:00:00

abstract：:Milton Winternitz led Yale Medical School as its Dean from 1920 to 1935. An innovative, even maverick leader, he not only kept the school from going under, but turned it into a first-class research institution. Dedicated to the new scientific medicine established in Germany, he was equally fervent about "social medici...

journal_title：Perspectives in biology and medicine

authors： Spiro H,Norton PW

更新日期：2003-07-01 00:00:00

abstract：:How can we provide the best care for growing numbers of very frail, very sick, or very old people? The disciplines of geriatrics, palliative care, and clinical ethics each have a good deal to offer to improve care for elders, yet each field is saddled with heavy historical baggage. Using a case as a springboard, we ad...

journal_title：Perspectives in biology and medicine

authors： Smith AK,Micco G

更新日期：2017-01-01 00:00:00

abstract：:The clinical trial of the AbioCor artificial heart, initiated in July 2001 and still in process, has taken place within a matrix of social and cultural patterns that are both "old" and new. The old patterns--those that have accompanied previous clinical trials of other vital artificial organs and transplantation in th...

journal_title：Perspectives in biology and medicine

authors： Fox RC,Swazey JP

更新日期：2004-01-01 00:00:00

abstract：:This is a daunting time, not only in terms of our public health and our economic health but also in terms of the health of the republic. It is an old theme that any form of popular government needs virtuous citizens if it is to survive. It also needs citizens to agree on what counts as a virtue. I fear that the pandem...

journal_title：Perspectives in biology and medicine

authors： Brudney D

更新日期：2020-01-01 00:00:00

abstract：:This paper reexamines the recent case of the conjoined twins from Malta. Survival was said to be possible only through separation, which would actually leave only one twin alive. The parents refused to allow the killing of one to save the other, but the court ruled that this would amount to the neglect of innocent lif...

journal_title：Perspectives in biology and medicine

authors： Barilan YM

更新日期：2002-10-01 00:00:00

abstract：:Social media use in modern medicine is fraught with ethical dilemmas and risks of unprofessional behavior. This essay surveys the existing literature on the possibilities and pitfalls of social media use by health-care professionals and concludes that non-engagement with social media is not an option. A mindful approa...

journal_title：Perspectives in biology and medicine

authors： Frischtak H,Sinha P

更新日期：2013-10-01 00:00:00

abstract：:As health care has become of great importance to both individual citizens and to society, it has become more important to understand medicine's relationship to the society it serves in order to have a basis for meaningful dialogue. During the past decade, individuals in the medical, legal, social sciences, and health ...

journal_title：Perspectives in biology and medicine

authors： Cruess RL,Cruess SR

更新日期：2008-10-01 00:00:00

abstract：:The concept of placebo has evolved over time. Generally believed to be the basis of the premodern pharmacopoeia, the placebo has been adopted in practice as a harmless but unscientific approach towards alleviating symptoms. Currently, many medical scientists view placebos pejoratively as confounding elements in the an...

journal_title：Perspectives in biology and medicine

authors： Kradin RL

更新日期：2004-07-01 00:00:00

abstract：:An intersex condition is one in which an individual is born with atypical male or female external genitalia, gonads, hormones, or chromosomes. Older terms, such as pseudohermaphroditism and hermaphroditism, are controversial, leading the Lawson Wilkins Pediatric Endocrine Society (LWPES) and the European Society for P...

journal_title：Perspectives in biology and medicine

authors： Reis E,McCarthy MW

更新日期：2016-01-01 00:00:00

abstract：:We argue that medical decisions on behalf of children should be made with the welfare of the child as the primary interest, that parents should generally be allowed to determine which options optimize the interests of their child, and that those decisions should be formally challenged only when the parental decision p...

journal_title：Perspectives in biology and medicine

authors： Diekema DS,Wilfond BS

更新日期：2016-01-01 00:00:00

abstract：:The advent of electronic health records (EHRs) to improve access and enable research in the everyday clinical world has simultaneously made medical information much more vulnerable to illicit, non-beneficent uses. This wealth of identified, aggregated data has and will attract attacks by domestic governments for surve...

journal_title：Perspectives in biology and medicine

authors： Graves S

更新日期：2013-01-01 00:00:00

abstract：:Ensuring experimental outcomes are of the highest clinical caliber is crucial prior to the introduction of germline genome editing. However, if we are to police scientific progress using probability or the potential to go wrong, then we must account for the specious standards of human reproduction. With 15% of clinica...

journal_title：Perspectives in biology and medicine

authors： O'Neill HC

更新日期：2020-01-01 00:00:00

abstract：:Both leading scientific journals and the popular press now regularly report the convincing evidence of massive environmental degradation and decline. Yet despite the seriousness of the problems, despite their anthropogenic nature, and despite their profound implications for present and future population health, such t...

journal_title：Perspectives in biology and medicine

authors： Levine BR

更新日期：2007-01-01 00:00:00

abstract：:The reigning paradigm of rational drug discovery in translational medicine attempts to exploit biological theories and pathophysiological explanations to identify novel drug targets and therapeutic strategies. Yet because many theories in medicine are either incomplete (at best) or false (at worst), relying on theoret...

journal_title：Perspectives in biology and medicine

authors： Hey SP

更新日期：2019-01-01 00:00:00

abstract：:While the necessity of normalizing surgery on intersexed individuals is a topic of ongoing debate in the 21st century, the origins of surgery as a therapeutic practice for ambiguous or unusual genitalia lie in the 19th century. The first report of corrective surgery published in the United States appeared in the Ameri...

journal_title：Perspectives in biology and medicine

authors： Matta C

更新日期：2005-01-01 00:00:00

abstract：:Over recent years there has been a gratifying decrease in the incidence of recorded deaths from coronary artery disease in the Western world. The common view is that coronary artery disease is a recent phenomenon, that we have been subject to an epidemic in the mid-20th century that is now tailing off, and that with a...

journal_title：Perspectives in biology and medicine

authors： John LC

更新日期：2012-01-01 00:00:00

abstract：:The emerging field of synthetic biology is a novel biological discipline at the interface between traditional biology, chemistry, and engineering sciences. Synthetic biology aims at the rational design of complex synthetic biological devices and systems with desired properties by combining compatible, modular biologic...

journal_title：Perspectives in biology and medicine

authors： Hörner M,Reischmann N,Weber W

更新日期：2012-01-01 00:00:00

abstract：:Biologists use models in two distinct ways that have not been clearly articulated. A model may be used either as an exemplar of a larger group, or as a surrogate for a specific target. Zebrafish serve as an exemplary model of vertebrates in developmental biology; rodents are both exemplary vertebrates and specific sur...

journal_title：Perspectives in biology and medicine

authors： Bolker JA

更新日期：2009-10-01 00:00:00

abstract：:This commentary considers two informing influences on Pope Francis's support of perinatal hospice care for families facing diagnoses of serious fetal anomalies. Reflecting on the morally formative scriptural narrative of Mary's pregnancy and Jesus's birth and drawing upon an often-repeated idea of Pope Francis's papac...

journal_title：Perspectives in biology and medicine

authors： Hardt J

更新日期：2020-01-01 00:00:00

abstract：:This article is concerned with the practice of bioethics outside of the Euro-American and Anglophone settings in which it was first formulated. In theoretical terms, the article considers the frictions that arise when global-scale projects such as bioethics are introduced into diverse social and cultural settings. Met...

journal_title：Perspectives in biology and medicine

authors： Simpson B

更新日期：2018-01-01 00:00:00

abstract：:Popular fiction responds to, and may exacerbate, public anxieties in ways that more highbrow literary texts may not. Robin Cook's 1977 novel Coma exemplifies the ways in which medical thrillers participate in the public discourse about health care. Written shortly after the medical establishment promoted "irreversible...

journal_title：Perspectives in biology and medicine

authors： Belling C

更新日期：2010-07-01 00:00:00

abstract：:The linguistic metaphor in biology adheres to a representational theory that seeks similarities between pre-given domains. The point of departure of this paper is the generative and nonrepresentational conception of metaphor. This paper argues that by adopting the nonrepresentational conception of metaphor, meaning-ma...

journal_title：Perspectives in biology and medicine

authors： Neuman Y

更新日期：2005-07-01 00:00:00