When medical cure is not an unmitigated good.

Abstract:

:The impact of chronic illness on patients has been discussed extensively, but little attention has been paid to the reverse situation: the need for patients who have been chronically ill since childhood to adjust to health and normality in adulthood. Drawing upon the narratives of two adults with childhood onset diseases, this paper provides a new perspective about the transition from chronic illness to health after a successful transplantation. We analyze from the patients' perspective the unusual disruptive impact of overcoming illness in such situations. The process of becoming cured affects their identity, leaving them unable to restructure their self within health and normality, in the same way as others are unable to adjust to chronic illness. Health care providers and families must pay more attention to the losses and life changes these patients undergo after being cured, and to their specific needs in the post-transplantation situation. We hope to offer insight into ways to prevent and address the difficulties and suffering in such situations, which may become more frequent as more therapeutic options become available for adults with childhood onset diseases.

journal_name

Perspect Biol Med

authors

Orfali K,Anderson-Shaw L

doi

10.1353/pbm.2005.0061

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

282-92

issue

2

eissn

0031-5982

issn

1529-8795

pii

S152987950520282X

journal_volume

48

pub_type

杂志文章
  • Putting concerns about nature in context: the case of agricultural biotechnology.

    abstract::Concerns about nature are playing increasingly prominent roles in a variety of social debates, including medical biotechnology, environmental protection, and agricultural biotechnology. These concerns are often simply rejected as incoherent: critics argue that there is no good account for how natural states of affairs...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2007.0049

    authors: Kaebnick GE

    更新日期:2007-10-01 00:00:00

  • The Need for Beneficence and Prudence in Clinical Innovation with Autologous Stem Cells.

    abstract::The term innovation is frequently used as a justification for allowing clinicians to offer unproven autologous stem cell-based interventions (SCBIs) to their patients. Proponents of this kind of innovation (which we refer to as "clinical innovation") argue that physicians should be free to administer whatever interven...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2018.0029

    authors: Lipworth W,Stewart C,Kerridge I

    更新日期:2018-01-01 00:00:00

  • A natural history of "agonist".

    abstract::This paper constructs a brief history of the biochemical term agonist by exploring the multiple meanings of the root agôn in ancient Greek literature and describing how agonist first appeared in the scientific literature of the 20th century in the context of neurophysiologists' debates about the existence and properti...

    journal_title:Perspectives in biology and medicine

    pub_type: 历史文章,杂志文章

    doi:10.1353/pbm.2002.0056

    authors: Russo R

    更新日期:2002-07-01 00:00:00

  • Torture in Abu Ghraib.

    abstract::Iraqi detainees subjected to torture and mistreatment at Abu Ghraib prison may continue to suffer from significant physical and psychological consequences of their abuse. This article reports two cases of Iraqi individuals allegedly tortured at Abu Ghraib. Detailed forensic evaluations were conducted approximately one...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2006.0059

    authors: Keller AS

    更新日期:2006-10-01 00:00:00

  • Let the shoemaker stick to his last: a defense of the "old" public health.

    abstract::The traditional forms of public health law were directed largely toward communicable diseases and other externalities, such as pollution, with negative health impacts. The more modern view treats any health issue that affects large numbers of individuals as one of public health, which would include such problems as ob...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Epstein RA

    更新日期:2003-07-01 00:00:00

  • A new curriculum to link the basic science of aging with geriatric practice.

    abstract::There is a growing national awareness that the extraordinary extension of life expectancy in our society poses an impending crisis for our health-care system. This is due in large part to the scarcity of primary-care providers, especially geriatricians. To address these concerns, the Obama administration has considere...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.0.0092

    authors: Hamerman D

    更新日期:2009-07-01 00:00:00

  • Expectations and obligations: professionalism and medicine's social contract with society.

    abstract::As health care has become of great importance to both individual citizens and to society, it has become more important to understand medicine's relationship to the society it serves in order to have a basis for meaningful dialogue. During the past decade, individuals in the medical, legal, social sciences, and health ...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章,评审

    doi:10.1353/pbm.0.0045

    authors: Cruess RL,Cruess SR

    更新日期:2008-10-01 00:00:00

  • Perspectives on brain tumor formation involving macrophages, glia, and neural stem cells.

    abstract::The incidence of brain tumors is rising in children and the elderly, but little is known about the mechanisms underlying brain tumor initiation and progression. In the 1940s, Zimmerman and coworkers exploited the tumor-promoting potential of polycyclic hydrocarbons to produce brain tumor models in adult mice that simu...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2001.0035

    authors: Seyfried TN

    更新日期:2001-04-01 00:00:00

  • The hitchhiker's guide to global health blogging.

    abstract::Social media use in modern medicine is fraught with ethical dilemmas and risks of unprofessional behavior. This essay surveys the existing literature on the possibilities and pitfalls of social media use by health-care professionals and concludes that non-engagement with social media is not an option. A mindful approa...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2013.0039

    authors: Frischtak H,Sinha P

    更新日期:2013-10-01 00:00:00

  • Charles Dickens and the movement for sanitary reform.

    abstract::Charles Dickens's adult life parallels the period when the movement for sanitary reform took root in England. Although he was not one of its leaders, he became in time one of its most outspoken advocates. This essay describes Dickens's growing involvement in the sanitary movement and looks at one of the most important...

    journal_title:Perspectives in biology and medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1353/pbm.2003.0025

    authors: Litsios S

    更新日期:2003-04-01 00:00:00

  • Heuristics and Explanation in Translational Medicine.

    abstract::The reigning paradigm of rational drug discovery in translational medicine attempts to exploit biological theories and pathophysiological explanations to identify novel drug targets and therapeutic strategies. Yet because many theories in medicine are either incomplete (at best) or false (at worst), relying on theoret...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2019.0039

    authors: Hey SP

    更新日期:2019-01-01 00:00:00

  • Reflections on basic science.

    abstract::After almost 50 years in science, I believe that there is an acceptable, often advantageous chasm between open-ended basic research-free exploration without a practical destination and in which the original ideas may fade into new concepts-and translational research or clinical research. My basic research on crystalli...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2010.0000

    authors: Piatigorsky J

    更新日期:2010-10-01 00:00:00

  • Regarding Bioethics: A Sociology of Morality.

    abstract::C. Wright Mills said that when done well, sociology illuminates the intersection of biography and history. This essay examines how the author's vocational choices and career path were shaped by historical circumstance, leading him to a degree in sociology and to participation in the odd and interesting interdiscipline...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2017.0020

    authors: De Vries R

    更新日期:2017-01-01 00:00:00

  • A consumer's guide to superorganisms.

    abstract::The organism, like the molecule, the cell, and the species, is one of the fundamental levels in our hierarchical classification of life and its components. The units ranked at these levels, being concrete, particular things, are individuals in the broadest philosophical sense. But in a much narrower and more familiar ...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2011.0022

    authors: Ghiselin MT

    更新日期:2011-04-01 00:00:00

  • Give me a break: Gerhard Küntscher and his nail.

    abstract::The treatment of broken bones has long adhered to principles of tight juxtaposition of fracture ends and of strict rest. Splinting and casting with plaster of Paris helped considerably. Attempts at internal splinting with pegs, bolts, or stabilizing contraptions usually failed. Foreign materials were either not biocom...

    journal_title:Perspectives in biology and medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1353/pbm.2014.0021

    authors: Pierach CA

    更新日期:2014-07-01 00:00:00

  • High-tech brains: a history of technology-based analogies and models of nerve and brain function.

    abstract::This article reviews some of the technological devices and ideas which have been used over the years to answer the question, how does the brain work? It describes some of the early technology-based analogies and models of nerve fibers, and then discusses other analogies and models of the brain based on mechanical and ...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章,评审

    doi:10.1353/pbm.2002.0033

    authors: Kirkland KL

    更新日期:2002-04-01 00:00:00

  • A Less Perfect Union.

    abstract::This is a daunting time, not only in terms of our public health and our economic health but also in terms of the health of the republic. It is an old theme that any form of popular government needs virtuous citizens if it is to survive. It also needs citizens to agree on what counts as a virtue. I fear that the pandem...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2020.0050

    authors: Brudney D

    更新日期:2020-01-01 00:00:00

  • Serving the Very Sick, Very Frail, and Very Old: Geriatrics, Palliative Care, and Clinical Ethics.

    abstract::How can we provide the best care for growing numbers of very frail, very sick, or very old people? The disciplines of geriatrics, palliative care, and clinical ethics each have a good deal to offer to improve care for elders, yet each field is saddled with heavy historical baggage. Using a case as a springboard, we ad...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2017.0039

    authors: Smith AK,Micco G

    更新日期:2017-01-01 00:00:00

  • Darwinism and the cultural evolution of sports.

    abstract::This article outlines a Darwinian approach to sports that takes into account its profoundly cultural character and thereby overcomes the traditional nature-culture dichotomies in the sociology of sport. We argue that there are good reasons to view sports as culturally evolved signaling systems that serve a function si...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.0.0063

    authors: De Block A,Dewitte S

    更新日期:2009-01-01 00:00:00

  • The Etiological Stance: Explaining Illness Occurrence.

    abstract::Kelly, Kelly, and Russo (2014) recently proposed to integrate biological, behavioral, and social mechanisms into "mixed mechanisms" situated in the individual's "lifeworld" when considering illness causation. This article suggests considering terminological discrepancies, replacing the pathogenetic with an etiological...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2017.0025

    authors: Dammann O

    更新日期:2017-01-01 00:00:00

  • Dean Milton C. Winternitz at Yale.

    abstract::Milton Winternitz led Yale Medical School as its Dean from 1920 to 1935. An innovative, even maverick leader, he not only kept the school from going under, but turned it into a first-class research institution. Dedicated to the new scientific medicine established in Germany, he was equally fervent about "social medici...

    journal_title:Perspectives in biology and medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1353/pbm.2003.0046

    authors: Spiro H,Norton PW

    更新日期:2003-07-01 00:00:00

  • "He knows that machine is his mortality": old and new social and cultural patterns in the clinical trial of the AbioCor artificial heart.

    abstract::The clinical trial of the AbioCor artificial heart, initiated in July 2001 and still in process, has taken place within a matrix of social and cultural patterns that are both "old" and new. The old patterns--those that have accompanied previous clinical trials of other vital artificial organs and transplantation in th...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2004.0006

    authors: Fox RC,Swazey JP

    更新日期:2004-01-01 00:00:00

  • "Meaning-making" in language and biology.

    abstract::The linguistic metaphor in biology adheres to a representational theory that seeks similarities between pre-given domains. The point of departure of this paper is the generative and nonrepresentational conception of metaphor. This paper argues that by adopting the nonrepresentational conception of metaphor, meaning-ma...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章,评审

    doi:10.1353/pbm.2005.0076

    authors: Neuman Y

    更新日期:2005-07-01 00:00:00

  • Telling stories about illness and disability: the limits and lessons of narrative.

    abstract::Autobiographical narratives of illness and disability are influential in popular and medical discourses of illness and disability, in part because these narratives represent illness and disability within a sociocultural context, intersecting with other categories of difference. Clinicians can benefit patients through ...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.0.0135

    authors: Garden R

    更新日期:2010-01-01 00:00:00

  • Global Bioethics: A Story of Dreams and Doubts from Bengal.

    abstract::This article is concerned with the practice of bioethics outside of the Euro-American and Anglophone settings in which it was first formulated. In theoretical terms, the article considers the frictions that arise when global-scale projects such as bioethics are introduced into diverse social and cultural settings. Met...

    journal_title:Perspectives in biology and medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1353/pbm.2018.0038

    authors: Simpson B

    更新日期:2018-01-01 00:00:00

  • "The visible skeleton series": the art of Laura Ferguson.

    abstract::Laura Ferguson's The Visible Skeleton Series constitutes an artistic self-representation of scoliosis. Ferguson employs high-tech medical imaging and innovative graphical techniques to suggest a novel view of her skeletal "deformity." This section presents introductions to the series by a historian of medicine and by ...

    journal_title:Perspectives in biology and medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1353/pbm.2004.0023

    authors: Dreger AD,Ferguson L,Aspinall C,Polly DW Jr,Beckwith JB

    更新日期:2004-04-01 00:00:00

  • Conceiving wholeness: women, motherhood, and ovarian transplantation, 1902 and 2004.

    abstract::Scholars have shown that organ transplantation may transform ideas about one's body, with recipients feeling that they are receiving not just a body part but also a part of the donor's identity. This article focuses on a different way in which organ transplantation shapes recipient identity: the idea of becoming whole...

    journal_title:Perspectives in biology and medicine

    pub_type: 历史文章,杂志文章

    doi:10.1353/pbm.2011.0036

    authors: Rodriguez SB,Campo-Engelstein L

    更新日期:2011-07-01 00:00:00

  • Science without laws.

    abstract::During the 1970s, something deeply consequential happened in the cultural, economic, and social relationships between science and technology. Paul Forman has proposed that the abrupt reversal of the culturally ascribed primacy in the science-technology relationship circa 1980 be taken as a demarcation of postmodernity...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.0.0074

    authors: Schweber SS

    更新日期:2009-01-01 00:00:00

  • The body, its emotions, the self, and consciousness.

    abstract::This article proposes a means for better understanding the self and consciousness. Data indicate that the basic "emotional brain" continually computes potential survival risk against reward to rank consequent "emotion scores" for all sensory inputs. These scores compete to yield winner-takes-all outcomes that determin...

    journal_title:Perspectives in biology and medicine

    pub_type: 杂志文章

    doi:10.1353/pbm.2012.0031

    authors: Boyd GW

    更新日期:2012-07-01 00:00:00

  • Contested boundaries: psychiatry, disease, and diagnosis.

    abstract::Since the 19th century, we have come to think of disease in terms of specific entities--entities defined and legitimated in terms of characteristic somatic mechanisms. Since the last third of that century, we have expanded would-be disease categories to include an ever-broader variety of emotional pain, idiosyncrasy, ...

    journal_title:Perspectives in biology and medicine

    pub_type: 历史文章,杂志文章

    doi:10.1353/pbm.2006.0046

    authors: Rosenberg CE

    更新日期:2006-07-01 00:00:00