Proximal Sessile Serrated Adenomas Are More Prevalent in Caucasians, and Gastroenterologists Are Better Than Nongastroenterologists at Their Detection.

Abstract:

Background and Aim:Proximal sessile serrated adenomas (PSSA) leading to colorectal cancer (CRC) represent an alternate pathway for CRC development. In this study, we aim to determine the prevalence of PSSAs and the impact of patient, colonoscopy, and endoscopist-related factors on PSSA detection. Methods:Patients ≥ 50 years of age undergoing a screening colonoscopy between 2012 and 2014 were included. Detection rates based on patient gender, race, colonoscopy timing, fellow participation, bowel preparation quality, and specialty of the endoscopist were calculated. t-tests were used to compare detection rates and a multivariate-adjusted analysis was performed. Results:140 PSSAs were detected from 4151 colonoscopies, with a prevalence of 3.4%. Detection rate was higher in Caucasians compared to African-Americans (AA) (3.7 ± 4.1 versus 0.96 ± 3.5; p < 0.001). Gastroenterologists detected more PSSAs compared to nongastroenterologists (3.9 ± 3.5 versus 2.2 ± 3.0; p = 0.028). These findings were still significant after adjusted multivariate analysis. The rest of the factors did not make significant difference in PSSA detection rate. Conclusions:PSSAs are more prevalent in Caucasians compared to AAs. Racial difference in prevalence of PSSAs is intriguing and warrants further investigation. Gastroenterologists have a significantly higher PSSADR compared to nongastroenterologists. Educational measures should be implemented in nongastroenterologists to improve their PSSA detection rates.

authors

Parikh MP,Muthukuru S,Jobanputra Y,Naha K,Gupta NM,Wadhwa V,Lopez R,Thota PN,Sanaka MR

doi

10.1155/2017/6710931

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

6710931

eissn

1687-6121

issn

1687-630X

journal_volume

2017

pub_type

杂志文章
  • Duodenal Rare Neuroendocrine Tumor: Clinicopathological Characteristics of Patients with Gangliocytic Paraganglioma.

    abstract::Gangliocytic paraganglioma (GP) has been regarded as a rare benign tumor that commonly arises from the second part of the duodenum. As GP does not exhibit either prominent mitotic activity or Ki-67 immunoreactivity, it is often misdiagnosed as neuroendocrine tumor (NET) G1. However, the prognosis might be better in pa...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2016/5257312

    authors: Okubo Y,Yokose T,Motohashi O,Miyagi Y,Yoshioka E,Suzuki M,Washimi K,Kawachi K,Nito M,Nemoto T,Shibuya K,Kameda Y

    更新日期:2016-01-01 00:00:00

  • Does Extending the Waiting Time of Low-Rectal Cancer Surgery after Neoadjuvant Chemoradiation Increase the Perioperative Complications?

    abstract::Background. Traditionally, rectal cancer surgery is recommended 6 to 8 weeks after completing neoadjuvant chemoradiation. Extending the waiting time may increase the tumor response rate. However, the perioperative complication rate may increase. The purpose of this study was to determine the association between extend...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/7870815

    authors: Timudom K,Phothong N,Akaraviputh T,Chinswangwatanakul V,Pongpaibul A,Petsuksiri J,Ithimakin S,Trakarnsanga A

    更新日期:2016-01-01 00:00:00

  • Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study.

    abstract::Aims. The association between Helicobacter pylori (H. pylori) infection and diarrhea-predominant irritable bowel syndrome (IBS-D) is still controversial. Here we performed a retrospective study to explore this issue. Methods. A total of 502 inpatients with Rome III confirmed IBS-D and known H. pylori status from 8 hos...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/3059201

    authors: Xiong F,Xiong M,Ma Z,Huang S,Li A,Liu S

    更新日期:2016-01-01 00:00:00

  • Perioperative Therapy of Oesophagogastric Adenocarcinoma: Mainstay and Future Directions.

    abstract::Perioperative chemotherapy improves overall survival in patients with oesophagogastric adenocarcinoma (OAC) and locoregional disease. The mainstay of perioperative chemotherapy in these patients is a platinum/fluoropyrimidine combination. The phase III FLOT4 trial has shown that the FLOT triplet regimen (oxaliplatin, ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2017/5651903

    authors: Bose K,Franck C,Müller MN,Canbay A,Link A,Venerito M

    更新日期:2017-01-01 00:00:00

  • Endosonographic features of histologically proven gastric ectopic pancreas.

    abstract::Gastric ectopic pancreas is an uncommon developmental anomaly and its histological diagnosis is usually difficult by using a conventional biopsy forceps. In the literature, most cases of gastric ectopic pancreas were usually diagnosed by gross pattern during endoscopic examination or features of endoscopic ultrasound....

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2014/160601

    authors: Chou JW,Cheng KS,Ting CF,Feng CL,Lin YT,Huang WH

    更新日期:2014-01-01 00:00:00

  • Antichronic Gastric Ulcer Effect of Zinc-Baicalin Complex on the Acetic Acid-Induced Chronic Gastric Ulcer Rat Model.

    abstract:Background:Baicalin (BA) has been shown to have anti-inflammatory and antioxidant activity. Zinc is a nutrient element. Objective:This study is aimed at investigating the antichronic gastric ulcer activity of Zn-Baicalin complex (BA-Zn) and its related mechanisms in an acetic acid-induced gastric ulcer rat model. Res...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2018/1275486

    authors: Yang H,Lu Y,Zeng XF,Li L,Zhang RP,Ren ZK,Liu X

    更新日期:2018-10-28 00:00:00

  • Circulating Oxidized Low-Density Lipoproteins and Antibodies against Oxidized Low-Density Lipoproteins as Potential Biomarkers of Colorectal Cancer.

    abstract::Introduction. The aim of the study was evaluation of the diagnostic utility of serum oxidized low-density lipoproteins (oxLDL), antibodies against oxLDLs (o-LAB), and CEA as risk markers of colorectal cancer (CRC). Material and Methods. The serum levels of study factors were measured in 73 patients with CRC and in 35 ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2015/146819

    authors: Diakowska D,Grabowski K,Nienartowicz M,Zarębski P,Fudalej K,Markocka-Mączka K

    更新日期:2015-01-01 00:00:00

  • Extrapolating Prognostic Factors of Primary Curative Resection to Postresection Recurrences Hepatocellular Carcinoma Treatable by Radiofrequency Ablation.

    abstract:Objective:Recurrence after curative resection for hepatocellular carcinoma (HCC) is a major cause of death from this disease. Factors of primary curative resection are available and potential in the prognosis of follow-up treatment. Our aim was to assess the prognostic significance of primary curative resection factors...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2021/8878417

    authors: Ma H,Li Z,Yuan J,Zhang L,Xie X,Yin X,Chen R,Ren Z

    更新日期:2021-01-02 00:00:00

  • Nutrient availability alters the effect of autophagy on sulindac sulfide-induced colon cancer cell apoptosis.

    abstract::Autophagy is a catabolic process by which a cell degrades its intracellular materials to replenish itself. Induction of autophagy under various cellular stress stimuli can lead to either cell survival or cell death via apoptotic and/or autophagic (nonapoptotic) pathways. The NSAID sulindac sulfide induces apoptosis in...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/897678

    authors: Chiou SK,Hoa N,Ge L,Jadus MR

    更新日期:2012-01-01 00:00:00

  • Influence of gastrectomy on cortical and cancellous bones in rats.

    abstract::The aim of the present study was to examine the influence of gastrectomy (GX) on cortical and cancellous bones in rats. Twenty male Sprague-Dawley rats were randomized into the two groups of 10 animals each: a sham operation (control) group and a GX group. Seven weeks after surgery, the bone mineral content and densit...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,收录出版

    doi:10.1155/2013/381616

    authors: Iwamoto J,Sato Y,Matsumoto H

    更新日期:2013-01-01 00:00:00

  • Corrigendum to "Incidence and Paris Classification of Pediatric Inflammatory Bowel Disease".

    abstract::[This corrects the article DOI: 10.1155/2014/904307.]. ...

    journal_title:Gastroenterology research and practice

    pub_type: 已发布勘误

    doi:10.1155/2015/804318

    authors: Müller KE,Lakatos PL,Papp M,Veres G

    更新日期:2015-01-01 00:00:00

  • T and N Staging of Gastric Cancer Using Dual-Source Computed Tomography.

    abstract:Aim:This study is aimed at comparing gastric cancer T and N staging between virtual monochromatic energy images and fusion images generated by dual-source computed tomography (DSCT) dual-energy mode data acquisition prospectively while measuring the iodine concentration of gastric cancer and lymph nodes at different T ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2018/5015202

    authors: Xie ZY,Chai RM,Ding GC,Liu Y,Ren K

    更新日期:2018-12-04 00:00:00

  • Results of Medium Seventeen Years' Follow-Up after Laparoscopic Choledochotomy for Ductal Stones.

    abstract::Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this st...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/9506406

    authors: Quaresima S,Balla A,Guerrieri M,Lezoche G,Campagnacci R,D'Ambrosio G,Lezoche E,Paganini AM

    更新日期:2016-01-01 00:00:00

  • Nutrition care for patients with weight regain after bariatric surgery.

    abstract::Achieving optimal weight outcomes for patients with obesity is important to the management of their chronic disease. All interventions present risks for weight regain. Bariatric surgery is the most efficacious treatment, producing greater weight losses that are sustained over more time compared to lifestyle interventi...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2013/256145

    authors: Johnson Stoklossa C,Atwal S

    更新日期:2013-01-01 00:00:00

  • The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss.

    abstract::The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endos...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2018/7823182

    authors: Ruban A,Ashrafian H,Teare JP

    更新日期:2018-07-26 00:00:00

  • Interobserver Agreement in the Diagnosis of Inflammatory Bowel Disease-Associated Neoplasia in China in Comparison to Subspecialized American Gastrointestinal Pathologists.

    abstract:Background:The aim of this study was to evaluate the interobserver variability in diagnosing inflammatory bowel disease (IBD)-associated neoplasia among practicing pathologists from China using telepathology, a practice of remote diagnostic consultation increasingly used nationally and internationally, and its comparis...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2018/8715263

    authors: Wu XR,Liu HS,Shi XY,Zhou WX,Jiang ZN,Huang Y,Karamchandani DM,Goldblum JR,Xiao SY,Zhu HF,Feely MM,Collinsworth AL,Esnakula A,Xie H,Shen B,Lan P,Liu XL

    更新日期:2018-04-23 00:00:00

  • 2017 Update on Ovarian Cancer Peritoneal Carcinomatosis Multimodal-Treatment Considerations.

    abstract::Ovarian cancer peritoneal carcinomatosis requires a multimodal-treatment approach. Current treatment considerations are analyzed in this update and include the management of recurrent malignant ascites and the understanding of its pathophysiology, the role of peritoneal washing cytology in detecting peritoneal metasta...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2018/5284814

    authors: Halkia E,Chrelias G,Chrelias C,Esquivel J

    更新日期:2018-04-05 00:00:00

  • The Differential Role of Human Cationic Trypsinogen (PRSS1) p.R122H Mutation in Hereditary and Nonhereditary Chronic Pancreatitis: A Systematic Review and Meta-Analysis.

    abstract:Background:Environmental factors and genetic mutations have been increasingly recognized as risk factors for chronic pancreatitis (CP). The PRSS1 p.R122H mutation was the first discovered to affect hereditary CP, with 80% penetrance. We performed here a systematic review and meta-analysis to evaluate the associations o...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2017/9505460

    authors: Hu C,Wen L,Deng L,Zhang C,Lugea A,Su HY,Waldron RT,Pandol SJ,Xia Q

    更新日期:2017-01-01 00:00:00

  • Changes in the Management of Patients with Crohn's Disease Based on Magnetic Resonance Enterography Patterns.

    abstract:Background and Aims:Magnetic resonance enterography (MRE) has become an important modality of radiological imaging in the evaluation of Crohn's disease (CD). The aim of this study was to investigate the impact of MRE in the assessment of disease activity and abdominal complications and in the making of therapeutic deci...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2019/3467316

    authors: Chinem ESS,Esberard BC,Moreira ADL,Barbassa TG,da Cunha GM,Carneiro AJV,de Souza HS,Carvalho ATP

    更新日期:2019-12-17 00:00:00

  • The Methylation Status and Expression of Epstein-Barr Virus Early Genes BARF1 and BHRF1 in Epstein-Barr Virus-Associated Gastric Carcinomas.

    abstract::Epstein-Barr virus (EBV) is an important DNA virus which establishes latent infection in human malignancies. Expression of EBV-encoded genes in the associated tumors is strongly modulated by promoter CpG methylation of EBV genome. This study aimed to explore the methylation status of the promoters of EBV BamHI-A right...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2017/3804146

    authors: Li J,Liu W,Che K,Zhang Y,Zhao Z,Luo B

    更新日期:2017-01-01 00:00:00

  • Pentraxin 3 Is a Predictor for Fibrosis and Arterial Stiffness in Patients with Nonalcoholic Fatty Liver Disease.

    abstract::Objective. The aim of the present study was to investigate whether pentraxin 3 (PTX3) can be a new noninvasive marker for prediction of liver fibrosis in patients with NAFLD. We also aimed to evaluate the relationship between PTX3 and atherosclerosis in patients with NAFLD. Method. Fifty-four male patients with biopsy...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/1417962

    authors: Ozturk K,Kurt O,Dogan T,Ozen A,Demirci H,Yesildal F,Kantarcioglu M,Turker T,Guler AK,Karslioglu Y,Altun B,Uygun A,Bagci S

    更新日期:2016-01-01 00:00:00

  • Tumor Regression Grade Predicts Survival in Locally Advanced Gastric Adenocarcinoma Patients with Lymph Node Metastasis.

    abstract:Background:Tumor regression grade (TRG) is widely used in gastrointestinal carcinoma to evaluate pathological responses to neoadjuvant chemotherapy (NCT), but whether it is an independent prognostic factor is still controversial. The aim of this study is to investigate the value of TRG in locally advanced gastric adeno...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2020/3435673

    authors: Tong Y,Zhu Y,Zhao Y,Shan Z,Zhang J,Liu D

    更新日期:2020-07-18 00:00:00

  • Establishment of a standardized liver fibrosis model with different pathological stages in rats.

    abstract::Objective. To establish a standardized animal model for liver fibrosis with the same assessment criteria for liver fibrosis studies that have been established on a unified platform. Methods. The standardized liver fibrosis model was established using Sprague-Dawley (SD) rats that either received an intraperitoneal inj...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/560345

    authors: Li L,Hu Z,Li W,Hu M,Ran J,Chen P,Sun Q

    更新日期:2012-01-01 00:00:00

  • Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis.

    abstract:Background:We conducted this meta-analysis to compare the efficacy and safety of simultaneous hepatectomy and splenectomy (HS) with hepatectomy alone (HA) in patients with hepatocellular carcinoma (HCC) and hypersplenism. Materials and Methods:A systematic search was conducted in PubMed, Embase, Cochrane Library, and ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2019/9065845

    authors: Liu X,Chen Z,Yu M,Zhou W,Zhi X,Li T

    更新日期:2019-08-14 00:00:00

  • Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages.

    abstract::Aims. To understand the feasibility and efficacy of treatment with SAMe in patients with hepatitis B-related HCC with different Barcelona Clinic Liver Cancer (BCLC) stages. Methods. We retrospectively enrolled 697 patients with BCLC early-stage (stages 0-A) and advanced-stage (stages B-C) HCC who underwent SAMe therap...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/4134053

    authors: Guo T,He Y,Ma W,Liu Z,Liu Q

    更新日期:2016-01-01 00:00:00

  • Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity.

    abstract:OBJECTIVE:To investigate the differences in the results of esophageal function tests for functional heartburn (FH) and reflux hypersensitivity (RH). METHODS:Patients with FH and RH and healthy volunteers (HVs) from the Department of Gastroenterology, Beijing Anzhen Hospital and Beijing Chao-Yang hospital, who underwen...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2017/3596148

    authors: Gao F,Gao Y,Chen X,Qian J,Zhang J

    更新日期:2017-01-01 00:00:00

  • Erythromycin for Promoting the Postpyloric Placement of Feeding Tubes: A Systematic Review and Meta-Analysis.

    abstract:Background:Critically ill patients can benefit from enteral nutrition with postpyloric feeding tubes, but the low success rate limits its wide use. Erythromycin could elevate the success rate of tube insertion, but its clinical efficiency still remains controversial. Methods:Included studies must be RCTs which assesse...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2018/1671483

    authors: Jiang QJ,Jiang CF,Chen QT,Shi J,Shi B

    更新日期:2018-04-03 00:00:00

  • Clinical Significance of Peripheral Blood T Lymphocyte Subsets in Helicobacter pylori-Infected Patients.

    abstract::Background. Helicobacter pylori chronically colonizes gastric/duodenal mucosa and induces gastroduodenal disease and vigorous humoral and cellular immune responses. Methods. In order to clarify the immunological changes induced by this infection, we determined the percentage and, as indicated, ratios of the following ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/819842

    authors: Satoh Y,Ogawara H,Kawamura O,Kusano M,Murakami H

    更新日期:2012-01-01 00:00:00

  • Intraluminal Administration of Resiniferatoxin Protects against Clostridium difficile Toxin A-Induced Colitis.

    abstract::Clostridium difficile toxin A is a colonic inflammatory agent that acts partially by activation of TRPV1 (transient receptor potential vanilloid type 1). Resiniferatoxin (RTX) is an excitotoxin that activates TRPV1 at low concentrations and defunctionalizes TRPV1 at high concentrations. RTX at various doses was inject...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2017/8438172

    authors: Vigna SR

    更新日期:2017-01-01 00:00:00

  • A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality.

    abstract::Corrosive injury results from the intake of corrosive-acid-based chemicals. However, this phenomenon is limited to a small number of cases and cannot be extrapolated to the epidemiology of corrosive injuries in actual situations. This study focuses on the annual incidence of corrosive injury and its connection to gend...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/7905425

    authors: Chen CM,Chung YC,Tsai LH,Tung YC,Lee HM,Lin ML,Liu HL,Tang WR

    更新日期:2016-01-01 00:00:00