Abstract:
INTRODUCTION:This multi-center, hospital-based observational study determined the seroprevalence of pertussis antibodies amongst healthcare professionals from three different hospitals in Spain to ascertain the health status of professionals attending to susceptible groups who are at risk of contracting and transmitting pertussis. METHODS:Medical professionals from three hospitals in Spain were recruited for this study (NCT01706224). Serum samples from subjects were assessed for anti-pertussis antibodies by ELISA. The percentage of subjects positive for anti-pertussis antibodies were determined by age-strata, gender, vaccination status, professional level (physicians, nurses, ancillary nurses and midwives), hospital department, number of working years, numbers of hours spent with the patient as well as number of children in the household. RESULTS:Overall, 31.2% of subjects were seropositive; 3.3% of these healthcare professionals had ELISA values indicative of current or recent infection. There were no significant differences in terms of pertussis prevalence with respect to age, gender, hospital department, profession, number of working years and number of hours spent with patients. These levels of seronegativity amongst healthcare workers further strengthen the rationale for vaccination amongst this specific population against pertussis.
journal_name
Vaccinejournal_title
Vaccineauthors
Rodríguez de la Pinta ML,Castro Lareo MI,Ramon Torrell JM,García de Lomas J,Devadiga R,Reyes J,McCoig C,Tafalla M,García-Corbeira Pdoi
10.1016/j.vaccine.2015.12.036subject
Has Abstractpub_date
2016-02-17 00:00:00pages
1109-14issue
8eissn
0264-410Xissn
1873-2518pii
S0264-410X(15)01833-2journal_volume
34pub_type
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