Abstract:
:A rapid and effective RP-UHPLC-DAD method for enantioseparation of three flavanones, i.e., flavanone, naringenin, and hesperetin, was developed and validated. Chromatographic separation of the analytes was performed using a Chiralpak AD-3R analytical column under reverse phase conditions with methanol as the mobile phase. The method was validated in the concentration range of 0.2 to 50 µg/mL for enantiomers of flavanone and 0.5 to 50 µg/mL for enantiomers of naringenin and hesperetin. The limits of quantification were between 0.03 to 0.5 µg/mL. Intraday and interday precision were below 14% and accuracy varied from 0.04 to 8.17%.
journal_name
Chiralityjournal_title
Chiralityauthors
Baranowska I,Hejniak J,Magiera Sdoi
10.1002/chir.22559subject
Has Abstractpub_date
2016-02-01 00:00:00pages
147-52issue
2eissn
0899-0042issn
1520-636Xjournal_volume
28pub_type
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