Recent Developments of the Synthetic Biology Toolkit for Clostridium.

abstract：:Plasmodium vivax is increasingly the dominant species of malaria in the Greater Mekong Subregion (GMS), which is pursuing regional malaria elimination. P. vivax lineages in the GMS are poorly characterized. Currently, P. vivax reference genomes are scarce due to difficulties in culturing the parasite and lack of high-...

journal_title：Frontiers in microbiology

authors： Brashear AM,Huckaby AC,Fan Q,Dillard LJ,Hu Y,Li Y,Zhao Y,Wang Z,Cao Y,Miao J,Guler JL,Cui L

更新日期：2020-08-11 00:00:00

abstract：:Flavobacterium psychrophilum is a devastating bacterial pathogen of salmonids reared in freshwater worldwide. So far, serological diversity between isolates has been described but the underlying molecular factors remain unknown. By combining complete genome sequence analysis and the serotyping method proposed by Loren...

journal_title：Frontiers in microbiology

authors： Rochat T,Fujiwara-Nagata E,Calvez S,Dalsgaard I,Madsen L,Calteau A,Lunazzi A,Nicolas P,Wiklund T,Bernardet JF,Duchaud E

更新日期：2017-09-12 00:00:00

abstract：:Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable. Novel anti-virulence strategies will undoubtedly provide a path forward in combating these resistant bacterial infections. Sortase A (SrtA), an enzyme responsi...

journal_title：Frontiers in microbiology

authors： Zhang B,Teng Z,Li X,Lu G,Deng X,Niu X,Wang J

更新日期：2017-09-06 00:00:00

abstract：:This review describes target-enrichment approaches followed by next generation sequencing and their recent application to the research and diagnostic field of modern and past infectious human diseases caused by viruses, bacteria, parasites and fungi. ...

journal_title：Frontiers in microbiology

authors： Gaudin M,Desnues C

更新日期：2018-11-27 00:00:00

abstract：:Organic farming system and sustainable management of soil pathogens aim at reducing the use of agricultural chemicals in order to improve ecosystem health. Despite the essential role of microbial communities in agro-ecosystems, we still have limited understanding of the complex response of microbial diversity and comp...

journal_title：Frontiers in microbiology

authors： Lupatini M,Korthals GW,de Hollander M,Janssens TK,Kuramae EE

更新日期：2017-01-04 00:00:00

abstract：:Particle-associated bacteria (PAB) and free-living bacteria (FLB) from aquatic environments during phytoplankton blooms differ in their physical distance from algae. Both the interactions within PAB and FLB community fractions and their relationship with the surrounding environmental properties are largely unknown. He...

journal_title：Frontiers in microbiology

authors： Yang C,Wang Q,Simon PN,Liu J,Liu L,Dai X,Zhang X,Kuang J,Igarashi Y,Pan X,Luo F

更新日期：2017-06-30 00:00:00

abstract：:The meals from many oilseed crops have potential for biofumigation due to their release of biocidal compounds such as isothiocyanates (ITCs). Various ITCs are known to inhibit numerous pathogens; however, much less is known about how the soil microbial community responds to the different types of ITCs released from oi...

journal_title：Frontiers in microbiology

authors： Hu P,Hollister EB,Somenahally AC,Hons FM,Gentry TJ

更新日期：2015-01-07 00:00:00

abstract：:Metagenomic sequencing with the Oxford Nanopore MinION sequencer offers potential for point-of-care testing of infectious diseases in clinical settings. To improve cost-effectiveness, multiplexing of several, barcoded samples upon a single flow cell will be required during sequencing. We generated a unique sequencing ...

journal_title：Frontiers in microbiology

authors： Xu Y,Lewandowski K,Lumley S,Pullan S,Vipond R,Carroll M,Foster D,Matthews PC,Peto T,Crook D

更新日期：2018-09-19 00:00:00

abstract：:Pseudomonas aeruginosa uses quorum sensing (QS) to regulate the production of public goods such as the secreted protease elastase. P. aeruginosa requires the LasI-LasR QS circuit to induce elastase and enable growth on casein as the sole carbon and energy source. The LasI-LasR system also induces a second QS circuit, ...

journal_title：Frontiers in microbiology

authors： Yan H,Wang M,Sun F,Dandekar AA,Shen D,Li N

更新日期：2018-02-27 00:00:00

abstract：:Adaptation to changes in osmolarity is fundamental for the survival of living cells, and has implications in food and industrial biotechnology. It has been extensively studied in the yeast Saccharomyces cerevisiae, where the Hog1 stress activated protein kinase was discovered about 20 years ago. Hog1 is the core of th...

journal_title：Frontiers in microbiology

authors： Gonzalez R,Morales P,Tronchoni J,Cordero-Bueso G,Vaudano E,Quirós M,Novo M,Torres-Pérez R,Valero E

更新日期：2016-09-28 00:00:00

abstract：:Aspergillus exists commonly in many crops and any process of crop growth, harvest, storage, and processing can be polluted by this fungus. Once it forms a biofilm, Aspergillus can produce many toxins, such as aflatoxin B1 (AFB1), ochratoxin, zearalenone, fumonisin, and patulin. Among these toxins, AFB1 possesses the h...

journal_title：Frontiers in microbiology

authors： Wang Q,Yang Q,Wu W

更新日期：2020-03-27 00:00:00

abstract：:Litter decomposition is the key link between material circulation and energy flow in ecosystems, resulting from the activity of resident microbes and various enzymes. This study investigated enzyme activity in litter and associated microbial community characteristics to help clarify the internal mechanisms associated ...

journal_title：Frontiers in microbiology

authors： Jia T,Wang Y,Chai B

更新日期：2020-12-21 00:00:00

abstract：:Antibiotic treatment of sick dairy cattle is critical for the sustainability of this production system which is vital for food security and societal prosperity in many low and middle-income countries. Given the increasingly high levels of antibiotic resistance worldwide and the challenge this presents for the treatmen...

journal_title：Frontiers in microbiology

authors： Mainda G,Lupolova N,Sikakwa L,Richardson E,Bessell PR,Malama SK,Kwenda G,Stevens MP,Bronsvoort BMD,Muma JB,Gally DL

更新日期：2019-05-31 00:00:00

abstract：:The LhrC family of small regulatory RNAs (sRNAs) is known to be induced when the foodborne pathogen Listeria monocytogenes is exposed to infection-relevant conditions, such as human blood. Here we demonstrate that excess heme, the core component of hemoglobin in blood, leads to a strong induction of the LhrC family me...

journal_title：Frontiers in microbiology

authors： Dos Santos PT,Menendez-Gil P,Sabharwal D,Christensen JH,Brunhede MZ,Lillebæk EMS,Kallipolitis BH

更新日期：2018-03-27 00:00:00

abstract：:The use of excess conventional Phosphorus (P) fertilizers to improve agricultural productivity, in order to meet constantly increasing global food demand, potentially causes surface and ground water pollution, waterway eutrophication, soil fertility depletion, and accumulation of toxic elements such as high concentrat...

journal_title：Frontiers in microbiology

authors： Alori ET,Glick BR,Babalola OO

更新日期：2017-06-02 00:00:00

abstract：:Actinobacteria are important producers of bioactive compounds. Extreme ecosystems cause evolution of novel secondary metabolic pathways of Actinobacteria and increase the possible discovery of new biological functions of bioactive compounds. Here, we isolated 65 Actinobacteria from rhizosphere soil samples of Opuntia ...

journal_title：Frontiers in microbiology

authors： Qi D,Zou L,Zhou D,Chen Y,Gao Z,Feng R,Zhang M,Li K,Xie J,Wang W

更新日期：2019-06-28 00:00:00

abstract：:Crop protection anilinopyrimidine (AP) fungicides were introduced more than 20 years ago for the control of a range of diseases caused by ascomycete plant pathogens, and in particular for the control of gray mold caused by Botrytis cinerea. Although early mode of action studies suggested an inhibition of methionine bi...

journal_title：Frontiers in microbiology

authors： Mosbach A,Edel D,Farmer AD,Widdison S,Barchietto T,Dietrich RA,Corran A,Scalliet G

更新日期：2017-11-30 00:00:00

abstract：:We explore the potential of bacterial secretion systems as tools for genomic modification of human cells. We previously showed that foreign DNA can be introduced into human cells through the Type IV A secretion system of the human pathogen Bartonella henselae. Moreover, the DNA is delivered covalently attached to the ...

journal_title：Frontiers in microbiology

authors： Guzmán-Herrador DL,Steiner S,Alperi A,González-Prieto C,Roy CR,Llosa M

更新日期：2017-08-22 00:00:00

abstract：:Chagas disease (Cd) or American human trypanosomiasis is caused by Trypanosoma cruzi and affects ~7 million people, mostly in Latin America. The infective trypomastigote forms of the parasite can invade several human blood cell populations, including monocytes and dendritic cells (DC). Although these cells display a w...

journal_title：Frontiers in microbiology

authors： Lonien SCH,Malvezi AD,Suzukawa HT,Yamauchi LM,Yamada-Ogatta SF,Rizzo LV,Bordignon J,Pinge-Filho P

更新日期：2017-10-25 00:00:00

abstract：:Members of the genus Burkholderia (β-proteobacteria) have only recently been shown to be able to establish a nitrogen-fixing symbiosis with several legumes, which is why they are also referred to as β-rhizobia. Therefore, very little is known about the competitiveness of these species to nodulate different legume host...

journal_title：Frontiers in microbiology

authors： Lardi M,de Campos SB,Purtschert G,Eberl L,Pessi G

更新日期：2017-08-15 00:00:00

abstract：:Hepatitis E virus (HEV) is associated with acute hepatitis disease, which may lead to chronic disease in immunocompromised individuals. The disease is particularly severe among pregnant women (20-30% mortality). The only licensed vaccine against HEV, which is available in China, is the Escherichia coli purified recomb...

journal_title：Frontiers in microbiology

authors： Gupta J,Kaul S,Srivastava A,Kaushik N,Ghosh S,Sharma C,Batra G,Banerjee M,Shalimar,Nayak B,Ranjith-Kumar CT,Surjit M

更新日期：2020-02-06 00:00:00

abstract：:Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is an adaptive immune system that resists foreign genes through nuclease targeting in bacteria and archaea. In this study, we analyzed 68 strains of Lactobacillus casei group from the NCBI GenBank database, and bioinformatic tools were used to investig...

journal_title：Frontiers in microbiology

authors： Yang L,Li W,Ujiroghene OJ,Yang Y,Lu J,Zhang S,Pang X,Lv J

更新日期：2020-04-08 00:00:00

abstract：:Arid regions show relatively fewer species in comparison to better-watered biomes, but the competition for the few nutrients is very distinct. Here, in total 373 bacterial strains were isolated from rhizospheric soils obtained from three different sampling sites in Tunisia. Their potential for the production of antimi...

journal_title：Frontiers in microbiology

authors： Nasfi Z,Busch H,Kehraus S,Linares-Otoya L,König GM,Schäberle TF,Bachoual R

更新日期：2018-11-13 00:00:00

abstract：:Vachellia karroo (formerly Acacia karroo) is a wide-spread legume species indigenous to southern Africa. Little is known regarding the identity or diversity of rhizobia that associate with this plant in its native range in South Africa. The aims of this study were therefore: (i) to gather a collection of rhizobia asso...

journal_title：Frontiers in microbiology

authors： Beukes CW,Boshoff FS,Phalane FL,Hassen AI,le Roux MM,Stȩpkowski T,Venter SN,Steenkamp ET

更新日期：2019-06-04 00:00:00

abstract：:Human life expectancy is rapidly increasing with an associated increasing burden of chronic diseases, such as neurodegenerative diseases and cancer. However, there is limited progress in finding effective treatment for these conditions. For this reason, members of the genus Streptomyces have been explored extensively ...

journal_title：Frontiers in microbiology

authors： Ser HL,Tan LT,Law JW,Chan KG,Duangjai A,Saokaew S,Pusparajah P,Ab Mutalib NS,Khan TM,Goh BH,Lee LH

更新日期：2017-11-01 00:00:00

abstract：:The granular sludge process is an effective, low-footprint alternative to conventional activated sludge wastewater treatment. The architecture of the microbial granules allows the co-existence of different functional groups, e.g., nitrifying and denitrifying communities, which permits compact reactor design. However, ...

journal_title：Frontiers in microbiology

authors： Szabó E,Liébana R,Hermansson M,Modin O,Persson F,Wilén BM

更新日期：2017-05-01 00:00:00

abstract：:Our laboratory has previously developed a qRT-PCR assay to assess drug efficacy on the growth of Cryptosporidium parvum in vitro by detecting the levels of parasite 18S rRNA. This approach displayed up to four orders of magnitude of linear dynamic range and was much less labor-intensive than the traditional microscopi...

journal_title：Frontiers in microbiology

authors： Zhang H,Zhu G

更新日期：2015-09-22 00:00:00

abstract：:Historically, vaccines have been designed to mimic the immunity induced by natural exposure to the target pathogen, but this approach has not been effective for any parasitic pathogen of humans or complex pathogens that cause chronic disease in humans, such as Plasmodium. Despite intense efforts by many laboratories a...

journal_title：Frontiers in microbiology

authors： Proietti C,Doolan DL

更新日期：2015-01-22 00:00:00

abstract：:Pathogenic bacterial persisters are responsible for the recalcitrance of chronic and persistent infections to antimicrobial therapy. Although the mechanisms of persister formation and survival have been widely studied in Escherichia coli, persistence mechanisms in Staphylococcus aureus remain largely unknown. Here, we...

journal_title：Frontiers in microbiology

authors： Wang W,Chen J,Chen G,Du X,Cui P,Wu J,Zhao J,Wu N,Zhang W,Li M,Zhang Y

更新日期：2015-12-23 00:00:00

abstract：:Microbial communities in the endosphere of Salicaceae plants, poplar (Populus trichocarpa) and willow (Salix sitchensis), have been demonstrated to be important for plant growth promotion, protection from biotic and abiotic stresses, and degradation of toxic compounds. Our study aimed to investigate bio-control activi...

journal_title：Frontiers in microbiology

authors： Kandel SL,Firrincieli A,Joubert PM,Okubara PA,Leston ND,McGeorge KM,Mugnozza GS,Harfouche A,Kim SH,Doty SL

更新日期：2017-03-13 00:00:00