Detection of Viral Pathogens With Multiplex Nanopore MinION Sequencing: Be Careful With Cross-Talk.

abstract：:Retroviruses create permanently integrated proviruses that exist in the host genome. Retroviral genomes encode for functionally conserved gag, pro, pol, and env regions, as well as integrase (IN), which is required for retroviral integration. IN mediates viral genome insertion through 3' end processing of the viral DN...

journal_title：Frontiers in microbiology

authors： Bray S,Turnbull M,Hebert S,Douville RN

更新日期：2016-12-01 00:00:00

abstract：:Long-term monoculture cropping is usually accompanied by soil acidification and microbial community shifts. Soil aluminum ions are dissolved under acidic condition (pH < 5.0), and the resulting aluminum bioavailability can cause toxic effects in plants. In this study, we investigated the bacterial community compositio...

journal_title：Frontiers in microbiology

authors： Zhang S,Jiang Q,Liu X,Liu L,Ding W

更新日期：2020-11-30 00:00:00

abstract：:Microbiota research often assumes that differences in abundance and identity of microorganisms have unique influences on host physiology. To test this concept mechanistically, germ-free mice are colonized with microbial communities to assess causation. Due to the cost, infrastructure challenges, and time-consuming nat...

journal_title：Frontiers in microbiology

authors： Trinder M,Daisley BA,Dube JS,Reid G

更新日期：2017-04-28 00:00:00

abstract：:Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide epidemic. Among the different environmental factors, the gut microbiota is now considered as a key player interfering with energy metabolism and host susceptibility to several non-communicable diseases. Among the next-generation be...

journal_title：Frontiers in microbiology

authors： Cani PD,de Vos WM

更新日期：2017-09-22 00:00:00

abstract：:Iron is an essential but, in excess, toxic nutrient. Therefore, fungi evolved fine-tuned mechanisms for uptake and storage of iron, such as the production of siderophores (low-molecular mass iron-specific chelators). In Aspergillus fumigatus, iron starvation causes extensive transcriptional remodeling involving two ce...

journal_title：Frontiers in microbiology

authors： Haas H

更新日期：2012-02-06 00:00:00

abstract：:Emergence of multidrug-resistant Salmonella typhimurium strains, especially the ACSSuT and nalidixic acid R types, has significantly compromised the effectiveness of current strategies to control Salmonella infections, resulting in increased morbidity and mortality. Clinical S. typhimurium isolates recovered in Hong K...

journal_title：Frontiers in microbiology

authors： Wong MH,Chan EW,Liu LZ,Chen S

更新日期：2014-10-02 00:00:00

abstract：:The emergence of carbapenem-resistant Enterobacteriaceae (CRE) has become a major public health concern worldwide and a new challenge in the treatment of infectious diseases. The molecular characteristics of Enterobacter cloacae in Ningxia China are unknown. In this study, we reported 10 carbapenem-resistant E. cloaca...

journal_title：Frontiers in microbiology

authors： Shi Z,Zhao H,Li G,Jia W

更新日期：2017-01-31 00:00:00

abstract：:Candida species can cause severe infections associated with high morbidity and mortality. Therefore, it is essential to gain more insight into the anti-fungal host defense response. The advent of omics technology and development of advanced systems biology tools has permitted to approach this in an unbiased and quanti...

journal_title：Frontiers in microbiology

authors： Smeekens SP,van de Veerdonk FL,Netea MG

更新日期：2016-02-16 00:00:00

abstract：:Microbes play crucial roles in various biogeochemical processes in the ocean, including carbon (C), nitrogen (N), and phosphorus (P) cycling. Functional gene diversity and the structure of the microbial community determines its metabolic potential and therefore its ecological function in the marine ecosystem. However,...

journal_title：Frontiers in microbiology

authors： Wang Y,Zhang R,He Z,Van Nostrand JD,Zheng Q,Zhou J,Jiao N

更新日期：2017-06-21 00:00:00

abstract：:Sequencing and annotation was performed for two large double stranded DNA bacteriophages, φGrn1 and φSt2 of the Myoviridae family, considered to be of great interest for phage therapy against Vibrios in aquaculture live feeds. In addition, phage-host metabolic interactions and exploitation was studied by transcript pr...

journal_title：Frontiers in microbiology

authors： Skliros D,Kalatzis PG,Katharios P,Flemetakis E

更新日期：2016-11-14 00:00:00

abstract：:Helminth-derived molecules have the ability to modulate the host immune system. Our previous study identified a tetradecapeptide derived from Trichinella spiralis paramyosin (Ts-pmy) that could bind to human complement component C9 to inhibit its polymerization, making the peptide a candidate therapeutic agent for com...

journal_title：Frontiers in microbiology

authors： Chen Y,Shao S,Huang J,Gu Y,Cheng Y,Zhu X

更新日期：2020-12-23 00:00:00

abstract：:Previous studies had suggested the presence of ammonium oxidizing Thaumarchaeota as well as nitrite oxidizing Bacteria in the subsurface spring called Franz Josef Quelle (FJQ), a slightly radioactive thermal mineral spring with a temperature of 43.6-47°C near the alpine village of Bad Gastein, Austria. The microbiolog...

journal_title：Frontiers in microbiology

authors： Gerbl FW,Weidler GW,Wanek W,Erhardt A,Stan-Lotter H

更新日期：2014-05-16 00:00:00

abstract：:Copper membrane monooxygenases (CuMMOs) oxidize ammonia, methane and some short-chain alkanes and alkenes. They are encoded by three genes, usually in an operon of xmoCAB. We aligned xmo operons from 66 microbial genomes, including members of the Alpha-, Beta-, and Gamma-proteobacteria, Verrucomicrobia, Actinobacteria...

journal_title：Frontiers in microbiology

authors： Khadka R,Clothier L,Wang L,Lim CK,Klotz MG,Dunfield PF

更新日期：2018-10-29 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2019.01752.]. ...

journal_title：Frontiers in microbiology

authors： Frontiers Production Office.

更新日期：2019-09-24 00:00:00

abstract：:Human life expectancy is rapidly increasing with an associated increasing burden of chronic diseases, such as neurodegenerative diseases and cancer. However, there is limited progress in finding effective treatment for these conditions. For this reason, members of the genus Streptomyces have been explored extensively ...

journal_title：Frontiers in microbiology

authors： Ser HL,Tan LT,Law JW,Chan KG,Duangjai A,Saokaew S,Pusparajah P,Ab Mutalib NS,Khan TM,Goh BH,Lee LH

更新日期：2017-11-01 00:00:00

abstract：:Here, we review sexually transmitted diseases (STDs) caused by pathogenic bacteria and vaginal infections which result from an overgrowth of opportunistic bacterial microflora. First, we describe the STDs, the corresponding pathogens and the antimicrobials used for their treatment. In addition to the well-known diseas...

journal_title：Frontiers in microbiology

authors： Shaskolskiy B,Dementieva E,Leinsoo A,Runina A,Vorobyev D,Plakhova X,Kubanov A,Deryabin D,Gryadunov D

更新日期：2016-05-18 00:00:00

abstract：:Dendritic cells (DCs) and NK cells play a crucial role in the first phase of host defense against infections. Group B Streptococcus (GBS) and Streptococcus suis are encapsulated streptococci causing severe systemic inflammation, leading to septicemia and meningitis. Yet, the involvement of NK cells in the innate immun...

journal_title：Frontiers in microbiology

authors： Lemire P,Galbas T,Thibodeau J,Segura M

更新日期：2017-06-29 00:00:00

abstract：:Capsular polysaccharides (CPS), a major virulence factor in Streptococcus pneumoniae, become thicker during blood invasion while not during asymptomatic nasopharyngeal colonization. However, the underlying mechanism controlling this differential pneumococcal CPS regulation remain unclear. Here, we show how VncR, the r...

journal_title：Frontiers in microbiology

authors： Ghosh P,Shah M,Ravichandran S,Park SS,Iqbal H,Choi S,Kim KK,Rhee DK

更新日期：2019-10-01 00:00:00

abstract：:Synechococcus elongatus PCC 7942 is a paradigmatic model organism for nitrogen regulation in cyanobacteria. Expression of genes involved in nitrogen assimilation is positively regulated by the 2-oxoglutarate receptor and global transcriptional regulator NtcA. Maximal activation requires the subsequent binding of the c...

journal_title：Frontiers in microbiology

authors： Labella JI,Cantos R,Espinosa J,Forcada-Nadal A,Rubio V,Contreras A

更新日期：2017-07-11 00:00:00

abstract：:The bacterial catabolism of aromatic compounds has considerable promise to convert lignin depolymerization products to commercial chemicals. Alkylphenols are a key class of depolymerization products whose catabolism is not well-elucidated. We isolated Rhodococcus rhodochrous EP4 on 4-ethylphenol and applied genomic an...

journal_title：Frontiers in microbiology

authors： Levy-Booth DJ,Fetherolf MM,Stewart GR,Liu J,Eltis LD,Mohn WW

更新日期：2019-08-20 00:00:00

abstract：:The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that share structural and functional similarities and possess potent superantigenic activity causing disruptions in adaptive immunity. The enterotoxins can be separated into two groups; the classical (SEA-SEE) and the newer (SEG-SEl...

journal_title：Frontiers in microbiology

authors： Fisher EL,Otto M,Cheung GYC

更新日期：2018-03-13 00:00:00

abstract：:Cactaceae represents one of the most species-rich families of succulent plants native to arid and semi-arid ecosystems, yet the associations Cacti establish with microorganisms and the rules governing microbial community assembly remain poorly understood. We analyzed the composition, diversity, and factors influencing...

journal_title：Frontiers in microbiology

authors： Fonseca-García C,Coleman-Derr D,Garrido E,Visel A,Tringe SG,Partida-Martínez LP

更新日期：2016-02-12 00:00:00

abstract：:Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir. Omeprazole did not affect the antiviral effects of ribavirin in non-toxic concentrations up to 80 μg/mL but increased the acyc...

journal_title：Frontiers in microbiology

authors： Michaelis M,Kleinschmidt MC,Bojkova D,Rabenau HF,Wass MN,Cinatl J Jr

更新日期：2019-12-03 00:00:00

abstract：:Human gut bacteria contribute significantly to human health and several studies have evaluated the effects of dietary fibers on human gut bacterial ecology. However, the relationship between different degrees of fiber polymerization and human gut bacteria is unknown. Here, we analyzed three fiber substrates with diffe...

journal_title：Frontiers in microbiology

authors： Chen M,Fan B,Liu S,Imam KMSU,Xie Y,Wen B,Xin F

更新日期：2020-05-15 00:00:00

abstract：:Endophytic actinomycetes from medicinal plants produce a wide diversity of secondary metabolites (SM). However, to date, the knowledge about endophytes from Brazil remains scarce. Thus, we analyzed the antimicrobial potential of 10 actinomycetes isolated from the medicinal plant Vochysia divergens located in the Panta...

journal_title：Frontiers in microbiology

authors： Gos FMWR,Savi DC,Shaaban KA,Thorson JS,Aluizio R,Possiede YM,Rohr J,Glienke C

更新日期：2017-09-06 00:00:00

abstract：:The intestinal microbiota is a complex microbial community, with diverse and stable populations hosted by the gastrointestinal tract since birth. This ecosystem holds multiple anti-infectious, anti-inflammatory, and immune modulating roles decisive for intestinal homeostasis. Among these, colonization resistance refer...

journal_title：Frontiers in microbiology

authors： Iacob S,Iacob DG,Luminos LM

更新日期：2019-01-23 00:00:00

abstract：:Alternaria brassicicola is a necrotrophic fungus causing black spot disease and is an economically important seed-borne pathogen of cultivated brassicas. Seed transmission is a crucial component of its parasitic cycle as it promotes long-term survival and dispersal. Recent studies, conducted with the Arabidopsis thali...

journal_title：Frontiers in microbiology

authors： N'Guyen GQ,Raulo R,Marchi M,Agustí-Brisach C,Iacomi B,Pelletier S,Renou JP,Bataillé-Simoneau N,Campion C,Bastide F,Hamon B,Mouchès C,Porcheron B,Lemoine R,Kwasiborski A,Simoneau P,Guillemette T

更新日期：2019-08-30 00:00:00

abstract：:CRISPR-Cas systems adapt "memories" via spacers from viruses and plasmids to develop adaptive immunity against mobile genetic elements. Mature CRISPR RNAs guide CRISPR-associated nucleases to site-specifically cleave target DNA or RNA, providing an efficient genome engineering tool for organisms of all three kingdoms....

journal_title：Frontiers in microbiology

authors： Li Y,Peng N

更新日期：2019-10-25 00:00:00

abstract：:A novel Podoviridae lytic phage AJO2, specifically infecting Acinetobacter johnsonii, was isolated from bulking activated sludge. The one-step growth experiment showed that the latent period and burst size of AJO2 were estimated to be 30 min and 78.1 phages per infected cell, respectively. The viability test indicated...

journal_title：Frontiers in microbiology

authors： Fan N,Yang M,Jin R,Qi R

更新日期：2019-02-20 00:00:00

abstract：:In the last decades, pollution of the environment by large scale use of antibiotics in agriculture and human medicine have led to increased antimicrobial resistance in both the environment and the host animal microbiome. Disturbances in the host microbiome can result in impaired immunity and reduced resilience of aqua...

journal_title：Frontiers in microbiology

authors： López Nadal A,Peggs D,Wiegertjes GF,Brugman S

更新日期：2018-10-29 00:00:00