Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin.

abstract：:A multidisciplinary, collaborative project was conducted to determine the prevalence and distribution of soil-borne zoonotic pathogens in Lahore district of Pakistan and ascertain its Public Health Significance. Using a grid-based sampling strategy, soil samples (n = 145) were collected from villages (n = 29, 5 sample...

journal_title：Frontiers in microbiology

authors： Shabbir MZ,Jamil T,Ali AA,Ahmad A,Naeem M,Chaudhary MH,Bilal M,Ali MA,Muhammad K,Yaqub T,Bano A,Mirza AI,Shabbir MA,McVey WR,Patel K,Francesconi S,Jayarao BM,Rabbani M

更新日期：2015-09-10 00:00:00

abstract：:The betaproteobacterial genus Burkholderia is known for its versatile interactions with its hosts that can range from beneficial to pathogenic. A plant-beneficial-environmental (PBE) Burkholderia cluster was recently separated from the pathogen cluster, yet still little is known about burkholderial diversity, distribu...

journal_title：Frontiers in microbiology

authors： Bragina A,Cardinale M,Berg C,Berg G

更新日期：2013-12-18 00:00:00

abstract：:Photorhabdus luminescens TTO1 and Xenorhabdus nematophila HGB081 are insect pathogenic bacteria and producers of various structurally diverse bioactive natural products. In these entomopathogenic bacteria we investigated the role of the global regulators Lrp, LeuO, and HexA in the production of natural products. Lrp i...

journal_title：Frontiers in microbiology

authors： Engel Y,Windhorst C,Lu X,Goodrich-Blair H,Bode HB

更新日期：2017-02-17 00:00:00

abstract：:Marseilleviruses comprise a family of large double-stranded DNA viruses belonging to the proposed order "Megavirales." These viruses have a circular genome of ∼370 kbp, coding hundreds of genes. Over a half of their genes are associated with AT-rich putative promoter motifs, which have been demonstrated to be importan...

journal_title：Frontiers in microbiology

authors： Rodrigues RAL,Louazani AC,Picorelli A,Oliveira GP,Lobo FP,Colson P,La Scola B,Abrahão JS

更新日期：2020-04-14 00:00:00

abstract：:Background: BCG protection is suboptimal and there is significant interest to develop new tuberculosis (TB) vaccines. However, there are significant limitations of the current vaccine evaluation systems in the mouse model. Here, we developed a BCG-challenge rabbit skin model as a new way to evaluate the protective eff...

journal_title：Frontiers in microbiology

authors： Chen H,Liu X,Ma X,Wang Q,Yang G,Niu H,Li S,He B,He S,Dannenberg AM Jr,Zhu B,Zhang Y

更新日期：2017-05-17 00:00:00

abstract：:[This corrects the article on p. 37 in vol. 6, PMID: 25699029.]. ...

journal_title：Frontiers in microbiology

authors： Ungerfeld EM

更新日期：2015-06-02 00:00:00

abstract：:The present study aimed to understand the biofilm formation mechanism of Propionibacterium acnes by analyzing the components and structure of the biofilms. P. acnes strains were isolated from the surface of explanted cardiac pacemaker devices that exhibited no clinical signs of infection. Culture tests using a simple ...

journal_title：Frontiers in microbiology

authors： Okuda KI,Nagahori R,Yamada S,Sugimoto S,Sato C,Sato M,Iwase T,Hashimoto K,Mizunoe Y

更新日期：2018-02-14 00:00:00

abstract：:Capsaicin (CAP) reduces body weight mainly through activation of transient receptor potential vanilloid 1 (TRPV1) cation channel. However, recent evidence indicates that the gut microbiota influences many physiological processes in host and might provoke obesity. This study determined whether the anti-obesity effect o...

journal_title：Frontiers in microbiology

authors： Shen W,Shen M,Zhao X,Zhu H,Yang Y,Lu S,Tan Y,Li G,Li M,Wang J,Hu F,Le S

更新日期：2017-02-23 00:00:00

abstract：:Microbiota research often assumes that differences in abundance and identity of microorganisms have unique influences on host physiology. To test this concept mechanistically, germ-free mice are colonized with microbial communities to assess causation. Due to the cost, infrastructure challenges, and time-consuming nat...

journal_title：Frontiers in microbiology

authors： Trinder M,Daisley BA,Dube JS,Reid G

更新日期：2017-04-28 00:00:00

abstract：:Three chemical epigenetic modifiers [5-azacytidine, nicotinamide, and suberoylanilide hydroxamic acid (SAHA)] were applied to induce the metabolites of Penicillium mallochii CCH01, a fungus isolated from the gut of Ectropis oblique. Metabolite profiles of P. mallochii CCH01 were obviously changed by SAHA treatment. Fo...

journal_title：Frontiers in microbiology

authors： Zhang S,Fang H,Yin C,Wei C,Hu J,Zhang Y

更新日期：2019-10-02 00:00:00

abstract：:Climate change is accelerating the spread of plants and their associated species to new ranges. The differences in range shift capacity of the various types of species may disrupt long-term co-evolved relationships especially those belowground, however, this may be less so for seed-borne endophytic microbes. We collec...

journal_title：Frontiers in microbiology

authors： Geisen S,Kostenko O,Cnossen MC,Ten Hooven FC,Vreš B,van der Putten WH

更新日期：2017-08-29 00:00:00

abstract：:In this study, we have explored the impact of ascorbic acid on the transcriptome of Streptococcus pneumoniae D39. The expression of several genes and operons, including the ula operon (which has been previously shown to be involved in ascorbic acid utilization), the AdcR regulon (which has been previously shown to be ...

journal_title：Frontiers in microbiology

authors： Afzal M,Shafeeq S,Kuipers OP

更新日期：2015-02-11 00:00:00

abstract：:Tuberculosis (TB) is a health threat to the global population. Anti-TB drugs and vaccines are key approaches for TB prevention and control. TB animal models are basic tools for developing biomarkers of diagnosis, drugs for therapy, vaccines for prevention and researching pathogenic mechanisms for identification of tar...

journal_title：Frontiers in microbiology

authors： Zhan L,Tang J,Sun M,Qin C

更新日期：2017-05-04 00:00:00

abstract：OBJECTIVES:We investigated the management of staphylococcal abscesses (boils) by general practitioners (GPs) in the context of rising antibiotic resistance in community strains of Staphylococcus aureus. DESIGN, SETTING, PARTICIPANTS:We analyzed patient-reported management of 66 cases of uncomplicated skin abscesses fr...

journal_title：Frontiers in microbiology

authors： Parrott C,Wood G,Bogatyreva E,Coombs GW,Johnson PD,Bennett CM

更新日期：2016-06-06 00:00:00

abstract：:To date, nuclear localization signals (NLSs) that target proteins to nuclei in oomycetes have not been defined, but have been assumed to be the same as in higher eukaryotes. Here, we use the soybean pathogen Phytophthora sojae as a model to investigate these sequences in oomycetes. By establishing a reliable in vivo N...

journal_title：Frontiers in microbiology

authors： Fang Y,Jang HS,Watson GW,Wellappili DP,Tyler BM

更新日期：2017-02-02 00:00:00

abstract：:The gene pair hgcAB is essential for microbial mercury methylation. Our understanding of its abundance and diversity in nature is rapidly evolving. In this study we developed a new broad-range primer set for hgcAB, plus an expanded hgcAB reference library, and used these to characterize Hg-methylating communities from...

journal_title：Frontiers in microbiology

authors： Gionfriddo CM,Wymore AM,Jones DS,Wilpiszeski RL,Lynes MM,Christensen GA,Soren A,Gilmour CC,Podar M,Elias DA

更新日期：2020-10-06 00:00:00

abstract：:Although canine adenovirus (CAdV) is highly prevalent in dogs, there is currently a lack of a quick diagnostic method. In this study, we developed a rapid immunochromatographic strip (ICS) assay using colloidal gold coupled to CAdV-2-specific monoclonal antibodies (mAbs). BALB/c mice were immunized with a purified CAd...

journal_title：Frontiers in microbiology

authors： Wang S,Wen Y,An T,Duan G,Sun M,Ge J,Li X,Yang K,Cai X

更新日期：2019-12-11 00:00:00

abstract：:Staphylococcus aureus is one of the most important contagious mastitis pathogens in dairy cattle. Due to its zoonotic potential, control of S. aureus is not only of great economic importance in the dairy industry but also a significant public health concern. The aim of this study was to decipher the potential of bovin...

journal_title：Frontiers in microbiology

authors： Kümmel J,Stessl B,Gonano M,Walcher G,Bereuter O,Fricker M,Grunert T,Wagner M,Ehling-Schulz M

更新日期：2016-10-13 00:00:00

abstract：:The crosstalk between the gut microbiota and immune state of the host is an essential focus in academia and clinics. To explore the dynamic role of the microbiota in response to immune deficiency, we comprehensively assessed the microbiome of 90 mouse fecal samples, across three time points including two immunodeficie...

journal_title：Frontiers in microbiology

authors： Zheng S,Zhao T,Yuan S,Yang L,Ding J,Cui L,Xu M

更新日期：2019-11-01 00:00:00

abstract：:Salinity and pH have direct and indirect impacts on the growth and metabolic activities of microorganisms. In this study, the effects of salt and alkaline stresses on the kinetic balance between nitrous oxide (N2O) production and consumption in the denitrification pathway of Dechloromonas aromatica strain RCB were exa...

journal_title：Frontiers in microbiology

authors： Han H,Song B,Song MJ,Yoon S

更新日期：2019-06-05 00:00:00

abstract：:With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the huma...

journal_title：Frontiers in microbiology

authors： Rivière A,Selak M,Lantin D,Leroy F,De Vuyst L

更新日期：2016-06-28 00:00:00

abstract：:Losses in crop yields due to disease need to be reduced in order to meet increasing global food demands associated with growth in the human population. There is a well-recognized need to develop new environmentally friendly control strategies to combat bacterial crop disease. Current control measures involving the use...

journal_title：Frontiers in microbiology

authors： Buttimer C,McAuliffe O,Ross RP,Hill C,O'Mahony J,Coffey A

更新日期：2017-01-20 00:00:00

abstract：:The human T-lymphotropic virus (HTLV) is part of the group of retroviruses that share similar routes of transmission to the human immunodeficiency virus (HIV). Coinfection of these viruses can affect the clinical course of both infections, and reports have shown a quicker progression to AIDS and the development of HIV...

journal_title：Frontiers in microbiology

authors： Alencar SP,Souza MC,Fonseca RRS,Menezes CR,Azevedo VN,Ribeiro ALR,Lima SS,Laurentino RV,Barbosa MDAAP,Freitas FB,Oliveira-Filho AB,Machado LFA

更新日期：2020-10-22 00:00:00

abstract：:Nicotinamide adenine dinucleotides (NAD(H)) play a vital role in various biological processes, including keeping the cellular redox balance. In this study, we investigate the regulatory responses of Streptococcus pneumoniae D39 to NADH and characterize the role of the Rex protein as a transcriptional repressor of the ...

journal_title：Frontiers in microbiology

authors： Afzal M,Shafeeq S,Kuipers OP

更新日期：2018-06-19 00:00:00

abstract：:Marine microorganisms, particularly those residing in coastal areas, may come in contact with any number of chemicals of environmental or xenobiotic origin. The sensitivity and response of marine cyanobacteria to such chemicals is, at present, poorly understood. We have looked at the transcriptional response of well c...

journal_title：Frontiers in microbiology

authors： Tetu SG,Johnson DA,Varkey D,Phillippy K,Stuart RK,Dupont CL,Hassan KA,Palenik B,Paulsen IT

更新日期：2013-08-16 00:00:00

abstract：:Alternaria brassicicola is a necrotrophic fungus causing black spot disease and is an economically important seed-borne pathogen of cultivated brassicas. Seed transmission is a crucial component of its parasitic cycle as it promotes long-term survival and dispersal. Recent studies, conducted with the Arabidopsis thali...

journal_title：Frontiers in microbiology

authors： N'Guyen GQ,Raulo R,Marchi M,Agustí-Brisach C,Iacomi B,Pelletier S,Renou JP,Bataillé-Simoneau N,Campion C,Bastide F,Hamon B,Mouchès C,Porcheron B,Lemoine R,Kwasiborski A,Simoneau P,Guillemette T

更新日期：2019-08-30 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2018.03018.]. ...

journal_title：Frontiers in microbiology

authors： Liu YC,Hussain F,Negm O,Paiva AC,Halliday N,Dubern JF,Singh S,Muntaka S,Wheldon L,Luckett J,Tighe P,Bosquillon C,Williams P,Cámara M,Martínez-Pomares L

更新日期：2019-02-21 00:00:00

abstract：:Zoonotic hepatitis E, mainly caused by hepatitis E virus (HEV) genotype (gt) 3, is a foodborne disease that has emerged in Europe in recent decades. The main animal reservoir for genotype 3 is domestic pigs. Pig liver and liver derivates are considered the major risk products, and studies focused on the presence of HE...

journal_title：Frontiers in microbiology

authors： García N,Hernández M,Gutierrez-Boada M,Valero A,Navarro A,Muñoz-Chimeno M,Fernández-Manzano A,Escobar FM,Martínez I,Bárcena C,González S,Avellón A,Eiros JM,Fongaro G,Domínguez L,Goyache J,Rodríguez-Lázaro D

更新日期：2020-01-28 00:00:00

abstract：:The objective of this study was to evaluate the effects of wilting and Lactobacillus plantarum (LP) addition on the silage fermentation quality and microbial community of Moringa oleifera Lam. leaf silage. Unwilted (direct-cut) or wilted M. oleifera leaves were prepared either with or without LP (1.0 × 106 cfu/g) foll...

journal_title：Frontiers in microbiology

authors： Wang Y,Wang C,Zhou W,Yang FY,Chen XY,Zhang Q

更新日期：2018-08-06 00:00:00

abstract：:Microorganisms that utilize various D-amino acids (DAAs) were successfully isolated from deep-sea sediments. The isolates were phylogenetically assigned to Alphaproteobacteria, Gammmaproteobacteria, and Bacilli. Some of the isolates exhibited high enantioselective degradation activities to various DAAs. In particular,...

journal_title：Frontiers in microbiology

authors： Kubota T,Kobayashi T,Nunoura T,Maruyama F,Deguchi S

更新日期：2016-04-19 00:00:00