Abstract:
OBJECTIVE:Intracranial EEG (iEEG) or micro-electrocorticography (µECoG) microelectrodes offer high spatial resolution in recordings of neuronal activity from the exposed brain surface. Reliability of dielectric substrates and conductive materials of these devices are under intensive research in terms of functional stability in biological environments. APPROACH:The aim of our study is to investigate the stability of electroplated platinum recording sites on 16-channel, 8 micron thick, polyimide based, flexible µECoG arrays implanted underneath the skull of rats. Scanning electron microscopy and electrochemical impedance spectroscopy was used to reveal changes in either surface morphology or interfacial characteristics. The effect of improved surface area (roughness factor = 23 ± 0.12) on in vivo recording capability was characterized in both acute and chronic experiments. MAIN RESULTS:Besides the expected reduction in thermal noise and enhancement in signal-to-noise ratio (up to 39.8), a slight increase in the electrical impedance of individual sites was observed, as a result of changes in the measured interfacial capacitance. In this paper, we also present technology processes and protocols in detail to use such implants without crack formation of the porous platinum surfaces. SIGNIFICANCE:Our findings imply that black-platinum coating deposited on the recording sites of flexible microelectrodes (20 microns in diameter) provides a stable interface between tissue and device.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Zátonyi A,Fedor F,Borhegyi Z,Fekete Zdoi
10.1088/1741-2552/aacf71subject
Has Abstractpub_date
2018-10-01 00:00:00pages
054003issue
5eissn
1741-2560issn
1741-2552journal_volume
15pub_type
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abae8a
更新日期:2020-09-18 00:00:00
abstract:OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
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journal_title:Journal of neural engineering
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/2/025014
更新日期:2011-04-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066008
更新日期:2015-12-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/1/016008
更新日期:2014-02-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab7c19
更新日期:2020-03-03 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/1/016005
更新日期:2013-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
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journal_title:Journal of neural engineering
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab208c
更新日期:2019-07-30 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2552/aa6cbb
更新日期:2017-08-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aaa8a4
更新日期:2018-04-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 临床试验,杂志文章
doi:10.1088/1741-2552/aabc9b
更新日期:2018-08-01 00:00:00
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更新日期:2020-08-25 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aac313
更新日期:2018-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1088/1741-2552/aac3f7
更新日期:2018-08-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066019
更新日期:2015-12-01 00:00:00
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更新日期:2020-06-12 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/046002
更新日期:2013-08-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aacdbb
更新日期:2018-10-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章,随机对照试验
doi:10.1088/1741-2560/11/6/066004
更新日期:2014-12-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab8e8f
更新日期:2020-04-29 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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更新日期:2018-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-12-03 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/3/035001
更新日期:2011-06-01 00:00:00