Abstract：
PURPOSE:This work describes the performance characterization of a cone-beam CT-guided radiosurgery device, the Gamma Knife® Icon™. METHODS:The performance tests have been categorized into: (a) image quality and mechanical integrity; (b) image coregistration fidelity; (c) adaptive treatment delivery quality; (d) high definition motion management performance characterization; (e) software communication performance testing of the integrated cone-beam CT (CBCT) system. RESULTS:All image quality performance characterization satisfied or exceeded manufacturer specifications. The image quality and mechanical stability of the CBCT system over a 3-month period was within tolerance with negligible (<0.1°) detector tilt angle. The CBCT definition of the stereotactic space had a measured average discrepancy of 0.15-0.16 mm in x, y, and z directions. On average, the high definition motion management system performance was within 0.05 mm with a residual offset of 0.15 mm when large displacements in a given direction were taken. The adaptive treatment delivery component as measured with CBCT coregistration of daily setups against reference setup images was accurate to within 0.2°. Comprehensive end-to-end testing showed a total uncertainty of better than 0.2 mm in positioning and 0.4% in dosimetry for treatment of centrally located lesions. CONCLUSIONS:A set of system performance characterization tests spanning all aspects of the Gamma Knife Icon are presented. Overall, the system performance was in line with manufacturer specifications.
journal_name
Med Physjournal_title
Medical physicsauthors
Sarfehnia A,Ruschin M,Chugh B,Yeboah C,Becker N,Cho YB,Lee Ydoi
10.1002/mp.13073subject
Has Abstractpub_date
2018-06-29 00:00:00eissn
0094-2405issn
2473-4209pub_type
杂志文章相关文献
MEDICAL PHYSICS文献大全abstract：PURPOSE:The ionizing radiation imparted to patients during computed tomography exams is raising concerns. This paper studies the performance of a scheme called dose reduction using prior image constrained compressed sensing (DR-PICCS). The purpose of this study is to characterize the effects of a statistical model of x...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4773866
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To describe Acuros® CTS, a new software tool for rapidly and accurately estimating scatter in x-ray projection images by deterministically solving the linear Boltzmann transport equation (LBTE). METHODS:The LBTE describes the behavior of particles as they interact with an object across spatial, energy, and dir...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.12850
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To quantify the needle tip detection errors in ultrasound images due to bevel-tip orientation in relation to the location on template grid. METHODS:Transrectal ultrasound (TRUS) system (BK Medical) with physical template grid and 18-gauge bevel-tip (20-deg beveled angle) brachytherapy needle (Bard Medical, Cov...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4734916
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Alpha-emitting radionuclides exhibit a potential advantage for cancer treatments because they release large amounts of ionizing energy over a few cell diameters (50-80 μm), causing localized, irreparable double-strand DNA breaks that lead to cell death. Radioimmunotherapy (RIT) approaches using monoclonal antib...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4921997
更新日期：2015-07-01 00:00:00
abstract：:New x-ray radiographic systems based on large-area flat-panel technology have revolutionized our capability to produce digital x-ray images. However, these imagers are extraordinarily expensive compared to the systems they are replacing. Hence, there is a need for a low-cost digital imaging system for general applicat...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2837288
更新日期：2008-03-01 00:00:00
abstract：PURPOSE:To present EBT2 film verification of treatment planning with the eXtend System, a relocatable frame system for multiple-fraction or serial multiple-session radiosurgery. METHODS:A human head shaped phantom simulated the verification process for fractionated Gamma Knife (GK) treatment. Phantom preparation for e...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4735487
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:We have investigated the dosimetric errors caused by the interplay between the motions of the LINAC and the tumor during the delivery of a volume modulated arc therapy treatment. This includes the development of an IMRT QA technique, applied here to evaluate RapidArc plans of varying complexity. METHODS:An IMR...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.3263614
更新日期：2010-01-01 00:00:00
abstract：:For obliquely incident photon beams, the buildup of dose with depth is markedly different from normally incident beams. However, relatively little data on this topic exists for high-energy photon beams of energy greater than 6 MV. Measurements of dose in the buildup region were made using a plane-parallel ionization c...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.596055
更新日期：1987-05-01 00:00:00
abstract：OBJECTIVE:Carbon ion particle therapy delivers sharp Bragg's peaks, and hence can produce dose delivery of very high precision and conformality. To complement this characteristic, particle therapy centers implement a number of technologies unique to these centers, and are not commonly known to the medical physics commu...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4735351
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Episcleral eye plaque brachytherapy has been utilized in the treatment of intra-ocular malignancies, delivering large prescription doses to the apex of the tumor. Advances in dose calculation and image guidance, via calibrated fundus images, enable localization of the tumor and determination of dose to the macu...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4735518
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:A dosimetric system formed by Gafchromic EBT2 radiochromic film and Epson Expression 10000XL flatbed scanner was commissioned for dosimetry. In this paper, several open questions concerning the commissioning of radiochromic films for dosimetry were addressed: (a) is it possible to employ this dosimetric system ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4772075
更新日期：2013-01-01 00:00:00
abstract：:Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three-dimensional dose deposited. A method for delivery verification that utilizes a measure...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1352579
更新日期：2001-04-01 00:00:00
abstract：PURPOSE:Magnetic resonance imaging (MRI)-guided percutaneous cryotherapy of abdominal lesions, an established procedure, uses MRI to guide and monitor the cryoablation of lesions. Methods to precisely guide cryotherapy probes with a minimum amount of trial-and-error are yet to be established. To aid physicians in attai...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.14116
更新日期：2020-06-01 00:00:00
abstract：:This paper compares the characteristics of three types of commercial p-type electron diodes specially designed for in vivo dosimetry (Scanditronix EDD2, Sun Nuclear QED 111200-0 and PTW T60010E diodes coupled with a Therados DPD510 dosimeter) in electron fields with energies from 4.5 to 21 MeV, and in conditions simil...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1630492
更新日期：2004-01-01 00:00:00
abstract：:With intensity-modulated radiotherapy (IMRT), a variety of user-defined dose distribution can be produced using inverse planning. The generalized equivalent uniform dose (gEUD) has been used in IMRT optimization as an alternative objective function to the conventional dose-volume-based criteria. The purpose of this st...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1897464
更新日期：2005-05-01 00:00:00
abstract：PURPOSE:To develop a method of using two-dimensional (2D) magnetic resonance thermometry, and three-dimensional (3D) Gaussian modeling to predict the volume, shape, and location of 1 day postoperative T1w high-intensity focused ultrasound lesions in medication refractory tremor patients; thereby facilitating a better c...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.13868
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:Onboard imaging-currently performed primarily by x-ray transmission modalities-is essential in modern radiation therapy. As radiation therapy moves toward personalized medicine, molecular imaging, which views individual gene expression, may also be important onboard. Nuclear medicine methods, such as single pho...
journal_title：Medical physics
pub_type： 信件
doi：10.1118/1.4845195
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:Melanoma is the most lethal of the three primary skin cancers, including also basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which are less lethal. The accepted diagnosis process involves manually observing a suspicious lesion through a Dermascope (i.e., a magnifying glass), followed by a biopsy....
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.14471
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:The aim of this work was to provide a novel description of how the radiotherapy community configures treatment planning system (TPS) radiation beam models for clinically used treatment machines. Here we describe the results of a survey of self-reported TPS beam modeling parameter values across different C-arm l...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.13892
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The management of thoracic malignancies with radiation therapy is complicated by continuous target motion. In this study, a real time motion analysis approach is proposed to improve the accuracy of patient setup. METHODS:For 11 lung cancer patients a long training fluoroscopy was acquired before the first trea...
journal_title：Medical physics
pub_type： 临床试验,杂志文章
doi：10.1118/1.4794489
更新日期：2013-04-01 00:00:00
abstract：:An easy-to-use phantom has been constructed for checking the accuracy of a stereotactic computed tomography localization system. This phantom has been used on a commercially available stereotactic radiosurgery system. With this system, the phantom reference point, whose location is established by means of a precision ...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.597034
更新日期：1993-03-01 00:00:00
abstract：PURPOSE:In radiotherapy (RT) based on magnetic resonance imaging (MRI) as the only modality, the information on electron density must be derived from the MRI scan by creating a so-called pseudo computed tomography (pCT). This is a nontrivial task, since the voxel-intensities in an MRI scan are not uniquely related to e...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4914158
更新日期：2015-04-01 00:00:00
abstract：:In nuclear magnetic resonance (NMR) imaging by the zeugmatographic methods, there is a common and unified theoretical description. All forms of two-dimensional and three-dimensional imaging involve NMR data which trace various geometric representations, in reciprocal transform space, of the subject's spatially blurred...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.595470
更新日期：1984-01-01 00:00:00
abstract：PURPOSE:To compare how the inclusion of the uncertainties in dose and optical density affects the results of the calibration of Gafchromic(®) EBT3 radiochromic films. METHODS:Five methods of least square minimization were compared for calibration of radiochromic films. These differed in the way in which the uncertaint...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4811238
更新日期：2013-07-01 00:00:00
abstract：:The purpose of the present study is to characterize electron contamination in photon beams in different clinical situations. Variations with field size, beam modifier (tray, shaping block) and source-surface distance (SSD) were studied. Percentage depth dose measurements with and without a purging magnet and replacing...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.1895793
更新日期：2005-05-01 00:00:00
abstract：:During the past decade the use of undersampled acquisition and constrained reconstruction have led to significant increases in data acquisition speed, SNR, spatial resolution and temporal resolution in MR imaging. When a separately acquired constraining image is combined with an angiographic time series the traditiona...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.4735797
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess, using an anthropomorphic digital phantom, the accuracy of algorithms in registering precontrast and contrast-enhanced computed tomography (CT) chest images for generation of iodine maps of the pulmonary parenchyma via temporal subtraction. MATERIALS AND METHODS:The XCAT...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.13496
更新日期：2019-05-01 00:00:00
abstract：:Neutron and photon energy spectra were measured in different depths and lateral positions in tissue-equivalent phantoms exposed to a therapeutical 14.1 MeV neutron beam. Intensity weighted mass energy absorption coefficients were derived for application in ionization chamber dosimetry in mixed neutron-gamma fields. Th...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.594744
更新日期：1980-09-01 00:00:00
abstract：PURPOSE:Given its sensitivity to anatomical variations, proton therapy is expected to benefit greatly from integration with magnetic resonance imaging for online anatomy monitoring during irradiation. Such an integration raises several challenges, as both systems mutually interact. The proton beam will experience quasi...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1002/mp.12961
更新日期：2018-07-01 00:00:00
abstract：:Various radionuclides have been proposed for systemic tumor therapy. However, in most dosimetric analysis of proposed radionuclides the charged particles are taken into consideration while the potential photons are ignored. The photons will cause undesirable irradiation of normal tissue, and increase the probability o...
journal_title：Medical physics
pub_type： 杂志文章
doi：10.1118/1.2229428
更新日期：2006-09-01 00:00:00
