Understanding radionuclide production in gas target systems: the effect of adsorption on the target body.

Abstract:

:Gas target systems have been used for decades on cyclotrons to produce radionuclides for medical imaging. However, the activity recovered from such targets is often lower than its theoretically predicted value. Past research has suggested that nuclide interactions with the walls of the target body may play a key role in the loss of recoverable radionuclide activity. Here, we consider gas targets and modify the standard radionuclide production equation by adding a loss term representing radionuclides depositing on the walls of the target. We derive the form of the deposition term based on a simple adsorption model which is then linearized by solving for leading order terms. The resulting production equation uses one fitting parameter to give an estimate of the recoverable activity produced in a target system, taking adsorption into account. The model is then fit to six data series, taken in-house and reported in the literature and a parity plot compares model predictions to experimental data. The model is able to better track the data than any previous models, and points towards a phenomenological understanding of adsorption in target systems.

journal_name

Phys Med Biol

authors

Zacchia NA,Buckley KR,Martinez GM,Ruth TJ,Martinez DM,Hoehr C

doi

10.1088/1361-6560/aadf7b

subject

Has Abstract

pub_date

2018-09-28 00:00:00

pages

195009

issue

19

eissn

0031-9155

issn

1361-6560

journal_volume

63

pub_type

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