Abstract:
:Gas target systems have been used for decades on cyclotrons to produce radionuclides for medical imaging. However, the activity recovered from such targets is often lower than its theoretically predicted value. Past research has suggested that nuclide interactions with the walls of the target body may play a key role in the loss of recoverable radionuclide activity. Here, we consider gas targets and modify the standard radionuclide production equation by adding a loss term representing radionuclides depositing on the walls of the target. We derive the form of the deposition term based on a simple adsorption model which is then linearized by solving for leading order terms. The resulting production equation uses one fitting parameter to give an estimate of the recoverable activity produced in a target system, taking adsorption into account. The model is then fit to six data series, taken in-house and reported in the literature and a parity plot compares model predictions to experimental data. The model is able to better track the data than any previous models, and points towards a phenomenological understanding of adsorption in target systems.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Zacchia NA,Buckley KR,Martinez GM,Ruth TJ,Martinez DM,Hoehr Cdoi
10.1088/1361-6560/aadf7bsubject
Has Abstractpub_date
2018-09-28 00:00:00pages
195009issue
19eissn
0031-9155issn
1361-6560journal_volume
63pub_type
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