Abstract：
:Diet is a component in the etiology of the two major causes of death in the United States, namely, cardiovascular disease and cancer. During the last decade, various organizations have suggested that we alter the "typical" American diet in order to decrease the incidence of these diseases even though both diseases are indisputably of multiple etiology. An implication behind these recommendations is that individuals will increase their longevity by changing their diets. The burden of proof falls on those proposing changes to the diet that such alterations will be safe and effective. In spite of our often indicted diet, mortality from heart disease and stroke continue to fall and deaths from diet-related cancers are static or dropping. Longevity in the U.S. is exceeded by only five countries, whose populations consume a diet similar to ours in four, and that in the fifth is approaching ours. While low-fat high-fiber diets probably have some beneficial effect vis-a-vis chronic diseases, it is likely that other risk factors contribute more to the total risk of disease. Therefore, it is illogical to expect dietary manipulation to offset significantly other concurrent risks such as heredity, tobacco use, hypertension, and obesity. Individuals who are at high risk for specific diseases should modify their diets to minimize this particular risk factor. Most Americans can safely reduce their intake of total calories, fat, sugar, and salt. Although this can be achieved most readily on a population basis by following a form of "prudent" diet, it is premature to promise medical benefits to individuals.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Klurfeld DM,Kritchevsky Ddoi
10.1080/07315724.1986.10720151subject
Has Abstractpub_date
1986-01-01 00:00:00pages
477-85issue
5eissn
0731-5724issn
1541-1087journal_volume
5pub_type
杂志文章abstract：OBJECTIVE AND METHODOLOGY:We determined the kinds and amounts of vitamin A compounds (retinol and various retinyl esters) circulating in serum and stored in liver and other selected tissues of ferrets, using high-performance liquid chromatography. RESULTS:The concentration of total retinyl esters in serum (43 +/- 1 mu...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1994.10718376
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:While most studies have shown an inverse relation between tea consumption and cardiovascular risk, other studies have shown opposite results. Aortic stiffness and wave reflections are markers of cardiovascular disease and prognosticators of cardiovascular risk. METHODS:The acute effect of black and green tea...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2006.10719535
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to investigate whether probiotics had an effect on proinflammatory markers and cytokines in overweight and obese individuals and whether they could have synergistic effects with weight-loss diets. METHODS:A total of 75 healthy overweight and obese individuals completed this ran...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2013.874937
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Epidemiological studies demonstrate an inverse relation between dietary flavonoid intake and cardiovascular risk. Recent studies with flavonoid-containing beverages suggest that the benefits of these nutrients may relate, in part, to improved endothelial function. OBJECTIVE:We hypothesized that dietary supp...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2007.10719590
更新日期：2007-04-01 00:00:00
abstract：:The relations of serum zinc (Zn) and copper (Cu) to serum total cholesterol (TC), low-density-lipoprotein and high-density-lipoprotein cholesterol (LDL-C and HDL-C) and triglycerides were investigated in a population-based sample of 399 men in Southern China. Serum Cu was inversely related to HDL-C (r = -0.21), while ...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1992.10718199
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to assess the effect of dietary restriction on tissue distribution of vitamin B-6 vitamers and activities of vitamin B-6 metabolizing enzymes in rats. METHODS:Male rats were subjected to a 40% dietary restriction for 10, 20 or 40 weeks. The tissue vitamin B-6 vitamer concentrati...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1999.10718842
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:Overfeeding with a high-fat and/or high-carbohydrate (CHO) diet is known to increase plasma concentrations of endotoxin (lipopolysaccharide [LPS]) that may lead to metabolic disturbances like insulin resistance. The impact of CHO quality (i.e., the glycemic index [GI]) independent of fat intake on metabolic e...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2016.1156036
更新日期：2017-01-01 00:00:00
abstract：:The tenth anniversary for the determination of magnesium in MBC shows progress, but fundamental questions are still unanswered. Uniformity of the methodology for the assay and the units for reporting the result is a key factor for the validity and comparability of results. There is relatively good agreement among inve...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1987.10720166
更新日期：1987-04-01 00:00:00
abstract：:Despite extensive studies in cancer prevention, the incidence of cancer is increasing. We review studies that have identified several biochemical and genetic defects as well as potential carcinogens in the diet, environmental factors, and lifestyle-related habits. Two of the biochemical abnormalities increased oxidati...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2014.1003419
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:The primary aim of this study was to assess the effects of dietary protein intake on energy restriction (ER)-induced changes in body mass and body composition. Clinical markers of metabolic and cardiovascular diseases were also measured. DESIGN:54 postmenopausal women, age 58 +/- 2 y, body mass index 29.6 +/...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2007.10719600
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:Vegetarians may be at risk of certain nutrient deficiencies, particularly vitamin B-12. Vitamin B-12 deficiency may increase plasma homocysteine concentration and thus may potentially increase the risk of cardiovascular disease in vegetarians. The purpose of this study was to assess and compare plasma homocys...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2010.10719811
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:We tested the hypothesis that pectin, a source of dietary fiber that delays gastric emptying, increases satiety. METHODS:Male (n = 49) and female (n = 25) US Army employees within normal weight limits were fasted overnight then fed 448 mL of orange juice on 2 separate days followed 4 hours later by 0.473 L o...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1997.10718708
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:The consequences of chronic, low grade lead (Pb) burden from earlier exposure on development of hypertension (HT) and cardiovascular disease is, at best, controversial, even though many epidemiological studies suggest the possibility. Accordingly, we examined ability of a short-term Pb challenge to cause late...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1994.10718451
更新日期：1994-12-01 00:00:00
abstract：UNLABELLED:Many publications indicate the beneficial effect of n-6 polyunsaturated fatty acids (n-6 PUFAs) in the control of coronary heart disease and diabetes, although the mechanism is not clear. Some of our previous results suggest that, in contrast to other lipids, n-6 PUFAs could have a permissive effect on carbo...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1987.10720202
更新日期：1987-10-01 00:00:00
abstract：OBJECTIVE:In Sprague-Dawley rats (SD), we compared two categories of natural dietary supplements that influence carbohydrate (CHO) metabolism via different basic mechanisms to ameliorate insulin resistance (IR) and elevated blood pressure (BP) associated with heavy sugar/starch consumption. Two dietary supplements (bea...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2013.770335
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:C-reactive protein (CRP) may directly affect the progression of atherosclerosis, and therefore, may be a target for reducing disease risk. The objective was to determine whether antioxidant supplementation reduces plasma CRP in active and passive smokers. DESIGN:Randomized, double-blind, placebo-controlled, ...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.2004.10719354
更新日期：2004-04-01 00:00:00
abstract：:Carbohydrate intolerance is positively correlated with saturated fat consumption. In contrast, individuals consuming diets comprised of polyunsaturated fatty acids (PUFA) have a lower incidence of diabetes mellitus (DM). To test the hypothesis that dietary fats may influence insulin sensitivity, insulin-stimulated glu...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1991.10718161
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVE:Matrix metalloproteinase (MMP)-9, also known as gelatinase B, is implicated in the development of hypertension and atherosclerotic plaque vulnerability to rupture, an important step in the etiology of cardiovascular diseases. Studies have suggested that flavonoid consumption may be cardioprotective, and its f...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章
doi：10.1080/07315724.2009.10719803
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:The salt (NaCl) content of bread, obtained from Belgium and 25 other regions or countries worldwide, was analyzed to evaluate the importance of bread as a source of dietary salt in a population. METHODS:A total of 1166 dried bread samples were analyzed using a hot HCl extraction technique followed by flame p...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1994.10718392
更新日期：1994-04-01 00:00:00
abstract：:Objective: To assess whether the nutritional risk classified by StrongKids is associated with anemia and inflammation (total leukocytes and C-reactive protein (CRP)), as well as to compare the ability of StrongKids with anthropometry in identifying these changes in hospitalized pediatric patients.Methods: Cross-sectio...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1750072
更新日期：2020-04-13 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess the effects of 3-day Islamic intermittent fasting (3d-IF) on cognitive performance and serum levels of neurotrophic factors (brain-derived neurotrophic factor [BDNF] and vascular endothelial growth factor [VEGF]) before and after repeated sprints. METHODS:Twenty-one physic...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2016.1256795
更新日期：2017-03-01 00:00:00
abstract：:The 12-hr profiles of plasma glucose and insulin concentrations in 26 normal subjects ingesting a diet high in carbohydrate, protein, or fat have been determined. The diets were isocaloric and were given as three identical meals 4 hrs apart. In males the high carbohydrate diet resulted in glucose profiles similar to t...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1985.10720086
更新日期：1985-01-01 00:00:00
abstract：:Exogenous, microbial beta-D-galactosidases are capable of effecting hydrolysis of lactose in situ in the gastrointestinal tract of lactase-deficient subjects when given as replacement therapy at mealtime. As its digestion products-glucose and galactose-are known to inhibit lactose hydrolysis in vitro, the effect of ad...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1986.10720131
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:We examined relationships of individual and environmental factors with obesity and trying to lose weight in rural residents. METHODS:The joint contributions of individual and environmental factors on obesity status (obese vs. morbidly obese) and trying to lose weight (yes vs. no) were evaluated using general...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2007.10719632
更新日期：2007-10-01 00:00:00
abstract：:To study the role of diet as a risk factor for coronary heart disease (CHD), 463 adults (25-65 years, 419 males) at risk of or with CHD were assigned to group A (n = 231) receiving a cardiovasoprotective diet or group B (n = 232) receiving a normal diet in a randomized, single-blind fashion. Age, sex, risk factors and...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.1992.10718242
更新日期：1992-08-01 00:00:00
abstract：OBJECTIVE:The study tested the hypothesis that inclusion of palm olein (45% of fat) in the fat blend of a milk-based infant formula decreases the absorption of fat and calcium. METHODS:Formula PO contained palm olein (45%) in addition to soy, coconut and high-oleic sunflower oils (20%, 20%, and 15%, respectively); For...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.1998.10718770
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:Magnesium (Mg) deficiency has been shown to increase substance P release and induce a pro-inflammatory response that can be attenuated with the administration of a substance P-antagonist. Neurogenic inflammation has also been implicated in traumatic brain injury (TBI), a condition where brain intracellular fr...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2004.10719398
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVE:There is indirect evidence suggesting that strawberries, containing several key nutrients, may be associated with the risk of cardiovascular disease (CVD). In the Women's Health Study, we examined strawberry intake for both its prospective association with CVD risk in 38,176 women and its cross-sectional asso...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2007.10719615
更新日期：2007-08-01 00:00:00
abstract：:Diabetes, the most common metabolic disease, is responsible for the deaths of over 300,000 Americans annually. The incidence of the disease increases with age and since the U.S. population is graying, prevalence is also increasing. Obesity and family history are strong predictors of diabetes. The etiology of Type II d...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1987.10720203
更新日期：1987-10-01 00:00:00
abstract：BACKGROUND:Iron and zinc deficiency remain substantial problems in small children in both developed and developing nations. Optimizing mineral absorption is an important strategy in minimizing this problem. OBJECTIVES:To assess the effects of beef and soy proteins on the bioavailability of non-heme iron and zinc in ch...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2006.10719512
更新日期：2006-02-01 00:00:00
