Relation of serum zinc and copper to lipids and lipoproteins: the Yi People Study.

Abstract:

:The relations of serum zinc (Zn) and copper (Cu) to serum total cholesterol (TC), low-density-lipoprotein and high-density-lipoprotein cholesterol (LDL-C and HDL-C) and triglycerides were investigated in a population-based sample of 399 men in Southern China. Serum Cu was inversely related to HDL-C (r = -0.21), while Zn/Cu ratio showed a positive association (r = 0.19). These relationships remained significant after adjusting for age, body mass index (kg/m2), physical activity, tobacco smoking and dietary cholesterol, fat, and fiber. While no significant association was observed between serum Cu and serum TC in univariate analysis, a significant negative association was observed in multivariate analysis, after adjustment for the above mentioned independent variables. No significant association between serum Cu and LDL-C was found. These observations, as well as those reported in other studies reviewed herein, suggest that Cu is implicated in the metabolism of HDL-C, although the mechanism involved is not fully understood. No significant associations were found between serum Zn and the lipid variables.

journal_name

J Am Coll Nutr

authors

He JA,Tell GS,Tang YC,Mo PS,He GQ

doi

10.1080/07315724.1992.10718199

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

74-8

issue

1

eissn

0731-5724

issn

1541-1087

journal_volume

11

pub_type

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