Biochemical antioxidant levels respond to supplementation with an enriched drink in frail elderly people.

Abstract:

OBJECTIVE:To investigate whether a drink enriched with essential vitamins and minerals can improve biochemical status of enzymatic and non-enzymatic antioxidants in frail elderly people. METHODS:A six-month randomized, double blind, placebo controlled intervention study. Frail elderly people 65 years of age or older, with a body mass index (BMI) below 25 kg/m(2) and residing in a home for the elderly or in sheltered housing. Enriched (with essential vitamins and minerals in 30% to 150% of RDA and higher levels of antioxidants) drink (n = 28) or placebo (n = 27) to be taken twice a day in addition to the normal food consumed. Plasma levels of vitamin C, vitamin E, antioxidant capacity (TEAC), cysteine, uric acid and whole blood levels of total thiol and glutathione peroxidase (GSH-Px), dietary intake. RESULTS:Changes in vitamin E (16 +/- 2 vs. 2 +/- 1 mmol/L), vitamin C (37 +/- 5 vs. 1 +/- 5 mmol/L), TEAC (38 +/- 15 vs. -10 +/- 11 mmol/L Trolox eq) and cysteine (17 +/- 10 vs. 0.4 +/- 6 mmol/L) were significantly different between groups (p < 0.05). There was a trend towards significant changes in erythrocyte glutathione peroxidase (-0.2 +/- 3 vs. -10 +/- 7 U/mg Hb, p = 0.097). Baseline dietary intake of antioxidant vitamins was below 2/3 RDA for a substantial proportion (43% to 76%) of subjects. CONCLUSIONS:Supplementation with an enriched drink can raise plasma levels of enzymatic and non-enzymatic antioxidants in frail elderly people.

journal_name

J Am Coll Nutr

authors

Wouters-Wesseling W,Wagenaar LW,de Groot LC,Bindels JG,van Staveren WA

doi

10.1080/07315724.2003.10719298

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

232-8

issue

3

eissn

0731-5724

issn

1541-1087

journal_volume

22

pub_type

临床试验,杂志文章,随机对照试验
  • Control of polyunsaturated acids in tissue lipids.

    abstract::Since the discovery in 1929 that certain polyunsaturated fatty acids (PUFA) are essential for life and health, intense investigation has revealed the multiplicity of members in each of several families of PUFA, no two of which are equivalent. The quantified nutrient requirements for the essential dietary precursors of...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/07315724.1986.10720125

    authors: Holman RT

    更新日期:1986-01-01 00:00:00

  • Aging in humans: a continuous 20-year study of physiologic and dietary parameters.

    abstract::The old adage, "You are what you eat," is not always reliable, as demonstrated in this mixed-longitudinal study of men that began in 1969. Mean values of percent body fat, total body potassium (TBK), and total serum cholesterol (SCHOL) did not show changes that correlated with any studied nutrient from repeated 4-day ...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.1992.10718265

    authors: Flynn MA,Nolph GB,Baker AS,Krause G

    更新日期:1992-12-01 00:00:00

  • A brief history of the surgery for obesity to the present, with an overview of nutritional implications.

    abstract::Massive obesity results in serious diseases, which are a major public health problem. Surgery is frequently the only means to achieve and sustain significant weight loss. This historical overview is aimed at providing knowledge and appreciation of this surgery to scientists in other complex areas of nutrition. The dev...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/07315724.2013.797854

    authors: Deitel M

    更新日期:2013-01-01 00:00:00

  • Functional and metabolic changes during feeding in gastrointestinal cancer.

    abstract::The impact of feeding a hypercaloric parenteral solution on N balance, energy metabolism, and muscle strength has been investigated in cachectic patients with gastrointestinal cancer and in malnourished patients without evidence of cancer (controls). Patients were examined during 5% dextrose administration (D5W) for 2...

    journal_title:Journal of the American College of Nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/07315724.1989.10720323

    authors: Goldstein SA,Elwyn DH,Askanazi J

    更新日期:1989-12-01 00:00:00

  • Optimal administration dosage of magnesium sulfate for torsades de pointes in children with long QT syndrome.

    abstract:BACKGROUND:Intravenous administration of magnesium sulphate (MgSO(4)) is a very effective and safe treatment for torsades de pointes (TdP) associated with acquired long QT syndrome (LQTS) in adults. Discussed here is the efficacy of MgSO(4) for TdP in children with congenital and acquired LQTS. METHODS:The optimal MgS...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2004.10719388

    authors: Hoshino K,Ogawa K,Hishitani T,Isobe T,Eto Y

    更新日期:2004-10-01 00:00:00

  • Effects of flavonoid-containing beverages and EGCG on endothelial function.

    abstract::Abnormalities of the vascular endothelium contribute to all stages of atherosclerosis from lesion development to clinical cardiovascular disease events. Recognized risk factors, including diabetes mellitus, hypertension, dyslipidemia, cigarette smoking, and sedentary lifestyle are associated with endothelial dysfuncti...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/07315724.2007.10719625

    authors: Shenouda SM,Vita JA

    更新日期:2007-08-01 00:00:00

  • Serum Homocysteine, Folate, and Vitamin B12 Levels in Patients with Systemic Lupus Erythematosus: A Meta-Analysis and Meta-Regression.

    abstract:BACKGROUND:Patients with systemic lupus erythematosus (SLE) have elevated cardiovascular risk. Hyperhomocysteinemia may be one of the contributing factors to this phenomenon. This study therefore aimed to compare the serum homocysteine levels and the levels of folate and vitamin B12, cofactors for homocysteine metaboli...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2020.1788472

    authors: Tsai TY,Lee TH,Wang HH,Yang TH,Chang IJ,Huang YC

    更新日期:2020-07-23 00:00:00

  • Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled trial.

    abstract:OBJECTIVE:The objective of this study was to evaluate the effects of daily dietary supplementation with 1.25 g or 2.5 g of docosahexaenoic (DHA), in the absence of eicosapentaenoic acid (EPA), on serum lipids and lipoproteins in persons with combined hyperlipidemia (CHL) [serum low-density lipoprotein cholesterol (LDL-...

    journal_title:Journal of the American College of Nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/07315724.1997.10718680

    authors: Davidson MH,Maki KC,Kalkowski J,Schaefer EJ,Torri SA,Drennan KB

    更新日期:1997-06-01 00:00:00

  • Low dietary vitamin D in mid-life predicts total mortality in men with hypertension: the Honolulu heart program.

    abstract:BACKGROUND:Vitamin D deficiency was associated with total mortality in previous epidemiological studies. Little is known about the effects of dietary vitamin D intake on mortality. We examined the association between mid-life dietary vitamin D intake and 45-year total mortality. METHODS:The Honolulu Heart Program is a...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2013.875363

    authors: Kojima G,Bell CL,Chen R,Ross GW,Abbott RD,Launer L,Lui F,Masaki K

    更新日期:2014-01-01 00:00:00

  • Food safety evaluation of crops produced through biotechnology.

    abstract::Agricultural biotechnology has been widely adopted in agriculture but is also the focus of controversy. Questions have arisen regarding food and environmental safety. In the US, responsibility for ensuring agricultural and environmental safety is delegated to the USDA and EPA, respectively. The FDA has primary respons...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/07315724.2002.10719261

    authors: Chassy BM

    更新日期:2002-06-01 00:00:00

  • Simultaneous Activation of Nrf2 and Elevation of Dietary and Endogenous Antioxidant Chemicals for Cancer Prevention in Humans.

    abstract::Despite extensive studies in cancer prevention, the incidence of cancer is increasing. We review studies that have identified several biochemical and genetic defects as well as potential carcinogens in the diet, environmental factors, and lifestyle-related habits. Two of the biochemical abnormalities increased oxidati...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/07315724.2014.1003419

    authors: Prasad KN

    更新日期:2016-01-01 00:00:00

  • Absorbability and cost effectiveness in calcium supplementation.

    abstract:BACKGROUND:Cost-effectiveness of calcium supplementation depends not only on the cost of the product but on the efficiency of its absorption. Published cost-benefit analyses assume equal bioavailability for all calcium sources. Some published studies have suggested that there are differences in both the bioavailability...

    journal_title:Journal of the American College of Nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/07315724.2001.10719038

    authors: Heaney RP,Dowell MS,Bierman J,Hale CA,Bendich A

    更新日期:2001-06-01 00:00:00

  • Influence of Energy Balance and Glycemic Index on Metabolic Endotoxemia in Healthy Men.

    abstract:OBJECTIVE:Overfeeding with a high-fat and/or high-carbohydrate (CHO) diet is known to increase plasma concentrations of endotoxin (lipopolysaccharide [LPS]) that may lead to metabolic disturbances like insulin resistance. The impact of CHO quality (i.e., the glycemic index [GI]) independent of fat intake on metabolic e...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2016.1156036

    authors: Breusing N,Lagerpusch M,Engstler AJ,Bergheim I,Mueller MJ,Bosy-Westphal A

    更新日期:2017-01-01 00:00:00

  • The Effect of Added Peanut Butter on the Glycemic Response to a High-Glycemic Index Meal: A Pilot Study.

    abstract:OBJECTIVE:The purpose of this pilot study was to determine whether supplementation of a high-glycemic index breakfast meal with peanut butter attenuates the glycemic response. METHODS:Sixteen healthy adults, aged 24.1 ± 3.5 years, reported in the morning to a nutrition assessment laboratory for two days of data collec...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2018.1519404

    authors: Lilly LN,Heiss CJ,Maragoudakis SF,Braden KL,Smith SE

    更新日期:2019-05-01 00:00:00

  • The Fat-to-Lean Mass Ratio Is Associated with Hyperinsulinemia in Healthy Mexican Adolescents.

    abstract::Objective: To evaluate whether the Fat-to-Lean Mass (FyM) ratio is associated to hyperinsulinemia in healthy adolescents.Methods: Apparently healthy adolescents aged 10 to 15 years that according to sex, age, and percentiles of body fat percent, were included and allocated into the groups with elevated (body fat perce...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2020.1752845

    authors: Gamboa-Gómez CI,Guerrero-Romero F,Aradillas-García C,Rodríguez-Morán M,Simental-Mendía LE

    更新日期:2020-10-12 00:00:00

  • Total nutritional support through the peritoneal cavity.

    abstract::We prepared ten dogs with intraperitoneal catheters to allow total nutritional support for 30 days by constant infusion of a solution containing 1.5% amino acid, 10% glucose, and 1% lipids at a rate of 4 ml/kg/hr. Seven dogs survived in apparent good health but with a 13.9 +/- 1.3% weight loss. There was no correlatio...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.1985.10720088

    authors: Gilsdorf RB,Selby RR,Schon DA,Potter JD

    更新日期:1985-01-01 00:00:00

  • Associations of adequate intake of calcium with diet, beverage consumption, and demographic characteristics among children and adolescents.

    abstract:OBJECTIVE:The objective of this study is to examine various factors associated with total calcium intake and percent adequate intake (% AI) of calcium by children and adolescents, with respect to age, gender, race/ethnicity, and diet and beverage choices. DESIGN:Data from the U.S. Department of Agriculture's Continuin...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2004.10719339

    authors: Storey ML,Forshee RA,Anderson PA

    更新日期:2004-02-01 00:00:00

  • Absorption and effect of the magnesium content of a mineral water in the human body.

    abstract:OBJECTIVE:The kinetics of magnesium (Mg) absorption, after drinking Magnesia mineral water (204 mg Mg/L), was investigated in healthy humans aged (23-60 yrs). METHODS:Serum Mg, calcium (Ca), potassium (K) and sodium (Na) content, blood hemoglobin, erythrocyte and white blood cell counts as well as urinary volume and u...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2004.10719424

    authors: Kiss SA,Forster T,Dongó A

    更新日期:2004-12-01 00:00:00

  • General and Central Adiposity in Older Adults in Palmas (TO): Prevalence and Associated Factors.

    abstract::Objectives: To evaluate the prevalence and associated factors with general and central adiposity in older adults in Palmas (TO).Methods: Cross-sectional study with older adults (≥60 years) of both sexes enrolled in the Family Health Strategy program in Palmas (TO). Sociodemographic aspects, health conditions, and func...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2020.1734989

    authors: Guimarães MSA,Santos KP,Castro JDS,Juvanhol LL,Rezende FAC,Ribeiro AQ

    更新日期:2020-11-01 00:00:00

  • Associations Among Fatty Acids, Desaturase and Elongase, and Insulin Resistance in Children.

    abstract:OBJECTIVES:Fatty acid profiles and desaturase (SCD-16, SCD018, D5D, D6D) and elongase (ELOVL6) enzyme activity have been associated with adiposity and metabolic disease. While this has been studied in adults, few studies have included children. The objective of this study was to evaluate these markers in children and i...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2017.1347908

    authors: Beccarelli LM,Scherr RE,Newman JW,Borkowska AG,Gray IJ,Linnell JD,Keen CL,Young HM

    更新日期:2018-01-01 00:00:00

  • Use of zinc tolerance test and 24-hour urinary zinc content to assess oral zinc absorption.

    abstract:OBJECTIVES:The sensitivity of one plasma and two urinary methods to assess zinc absorption after oral dosing were compared over the dose range of 10 to 100 mg. METHODS:Eleven healthy subjects participated in this four-way crossover design study. After an overnight fast, the subjects received a single oral dose of zinc...

    journal_title:Journal of the American College of Nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/07315724.1996.10718568

    authors: Henderson LM,Brewer GJ,Dressman JB,Swidan SZ,DuRoss DJ,Adair CH,Barnett JL,Berardi RR

    更新日期:1996-02-01 00:00:00

  • Efficacy of L-leucine Supplementation Coupled With Resistance Training in Untrained Midlife Women.

    abstract::Objective: This study investigated the effects of leucine supplementation with resistance training (RT) in untrained peri- and postmenopausal women on fat free mass, strength, and select anabolic-related hormones.Method: This was a randomized, double-blind, placebo-controlled trial, in which 36 untrained women were ra...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2019.1650675

    authors: Funderburk LK,Beretich KN,Chen MD,Willoughby DS

    更新日期:2020-05-01 00:00:00

  • The Nutrition Health Alliance (NutriHeAl) Study: A Randomized, Controlled, Nutritional Intervention Based on Mediterranean Diet in Greek Municipalities.

    abstract::Objective: The aim of this study was to evaluate the effects of Mediterranean diet on weight loss in a large population in a municipality setting.Methods: A 6-month nutritional intervention was implemented in 50 randomly selected municipalities in Greece. In each municipality, approximately 180 overweight or obese pat...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2019.1660928

    authors: Hassapidou M,Tziomalos K,Lazaridou S,Pagkalos I,Papadimitriou K,Kokkinopoulou A,Tzotzas T

    更新日期:2020-05-01 00:00:00

  • Magnesium retention in 12 to 48 month-old children.

    abstract:OBJECTIVES:In adults, adaptation to changes in magnesium intake is largely due to changes in fractional magnesium absorption and urinary magnesium excretion. We sought to examine whether these homeostatic mechanism also occurred in young children. METHODS:Children, 12-48 m old were studied (n=30). They were adapted to...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2008.10719711

    authors: Griffin IJ,Lynch MF,Hawthorne KM,Chen Z,Hamzo M,Abrams SA

    更新日期:2008-04-01 00:00:00

  • Cholesterol intake and plasma cholesterol: an update.

    abstract::The misperception that dietary cholesterol determines blood cholesterol is held by many consumers in spite of evidence to the contrary. Many studies reported over the past 2 years have shown that dietary cholesterol is not a significant factor in an individual's plasma cholesterol level or cardiovascular disease (CVD)...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,评审

    doi:

    authors: P2Namara DJ

    更新日期:1997-12-01 00:00:00

  • Bean amylase inhibitor and other carbohydrate absorption blockers: effects on diabesity and general health.

    abstract::Many believe that excessive intake of refined carbohydrates (CHO) plays a major role in the development of obesity/overweight, type 2 diabetes mellitus and insulin resistance, a collection of events commonly referred to as "diabesity," and have sought natural means to overcome these linked perturbations. As a first ap...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2009.10719781

    authors: Preuss HG

    更新日期:2009-06-01 00:00:00

  • Cookies enriched with psyllium or oat bran lower plasma LDL cholesterol in normal and hypercholesterolemic men from Northern Mexico.

    abstract:BACKGROUND:Psyllium and oat bran have been shown to lower plasma LDL cholesterol levels in different populations. Hypercholesterolemia is prevalent in the Northern part of Mexico and might be associated to dietary habits and sedentary lifestyle. METHODS:Sedentary normal (cholesterol<200 mg/dL) (n=36) and hypercholeste...

    journal_title:Journal of the American College of Nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/07315724.1998.10718809

    authors: Romero AL,Romero JE,Galaviz S,Fernandez ML

    更新日期:1998-12-01 00:00:00

  • Riboflavin status and its association with serum hs-CRP levels among clinical nurses with depression.

    abstract:OBJECTIVE:The objective of present study was to assess the relationship between the dietary intake and blood status of riboflavin and the prevalence of systemic inflammation among both depressed and nondepressed nurses. METHODS:This was a cross-sectional study on 98 female clinical nurses (45 depressed and 53 nondepre...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.2011.10719977

    authors: Naghashpour M,Amani R,Nutr R,Nematpour S,Haghighizadeh MH

    更新日期:2011-10-01 00:00:00

  • Renal excretion of ascorbic acid: effect of age and sex.

    abstract::To determine if the lower plasma ascorbic acid concentrations observed in males compared to females, and in the elderly in general, might be due to differences in renal clearances of ascorbic acid, tubular maximum reabsorptions (TmAA) and renal thresholds for ascorbic acid were determined on older (10 male, 10 female,...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章

    doi:10.1080/07315724.1993.10718349

    authors: Oreopoulos DG,Lindeman RD,VanderJagt DJ,Tzamaloukas AH,Bhagavan HN,Garry PJ

    更新日期:1993-10-01 00:00:00

  • A pilot, randomized, placebo-controlled, double-blind phase 0/biomarker study on effect of artepillin C-rich extract of Brazilian propolis in frequent colorectal adenoma polyp patients.

    abstract:OBJECTIVE:Brazilian propolis, a folk medicine, is used worldwide as an alternative medicine to prevent colon cancer. The objective of the study was to test in a small pilot biomarker study in a high-risk group the safety and efficacy of propolis for colon cancer prevention, which has not been evaluated in humans. METH...

    journal_title:Journal of the American College of Nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/07315724.2012.10720434

    authors: Ishikawa H,Goto M,Matsuura N,Murakami Y,Goto C,Sakai T,Kanazawa K

    更新日期:2012-10-01 00:00:00