Abstract:
OBJECTIVE:To investigate whether a drink enriched with essential vitamins and minerals can improve biochemical status of enzymatic and non-enzymatic antioxidants in frail elderly people. METHODS:A six-month randomized, double blind, placebo controlled intervention study. Frail elderly people 65 years of age or older, with a body mass index (BMI) below 25 kg/m(2) and residing in a home for the elderly or in sheltered housing. Enriched (with essential vitamins and minerals in 30% to 150% of RDA and higher levels of antioxidants) drink (n = 28) or placebo (n = 27) to be taken twice a day in addition to the normal food consumed. Plasma levels of vitamin C, vitamin E, antioxidant capacity (TEAC), cysteine, uric acid and whole blood levels of total thiol and glutathione peroxidase (GSH-Px), dietary intake. RESULTS:Changes in vitamin E (16 +/- 2 vs. 2 +/- 1 mmol/L), vitamin C (37 +/- 5 vs. 1 +/- 5 mmol/L), TEAC (38 +/- 15 vs. -10 +/- 11 mmol/L Trolox eq) and cysteine (17 +/- 10 vs. 0.4 +/- 6 mmol/L) were significantly different between groups (p < 0.05). There was a trend towards significant changes in erythrocyte glutathione peroxidase (-0.2 +/- 3 vs. -10 +/- 7 U/mg Hb, p = 0.097). Baseline dietary intake of antioxidant vitamins was below 2/3 RDA for a substantial proportion (43% to 76%) of subjects. CONCLUSIONS:Supplementation with an enriched drink can raise plasma levels of enzymatic and non-enzymatic antioxidants in frail elderly people.
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Wouters-Wesseling W,Wagenaar LW,de Groot LC,Bindels JG,van Staveren WAdoi
10.1080/07315724.2003.10719298subject
Has Abstractpub_date
2003-06-01 00:00:00pages
232-8issue
3eissn
0731-5724issn
1541-1087journal_volume
22pub_type
临床试验,杂志文章,随机对照试验abstract::Endogenous sulfite is generated as a consequence of the body's normal processing of sulfur-containing amino acids. Sulfites occur as a consequence of fermentation and also occur naturally in a number of foods and beverages. As food additives, sulfiting agents were first used in 1664 and approved in the United States a...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1995.10718500
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVE:To estimate the association of anembryonic pregnancy with 55 elements, homocysteine, folate and S-adenosylhomocysteine in pregnant women. METHODS:Thirty cases of anembryonic pregnancy were diagnosed using ultrasound scanning that showed an empty gestation sac with no embryo pole in the uterus. Additionally, ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2009.10719761
更新日期:2009-02-01 00:00:00
abstract::Prevention of vascular disease and acute pancreatitis is the goal of hyperlipidemia treatment. The risk of coronary heart disease (CHD) increases with increasing plasma cholesterol levels because low-density lipoprotein (LDL), the major carrier of cholesterol in the plasma, is atherogenic. High-density lipoprotein (HD...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1989.10737968
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:C-reactive protein is an acute-phase protein that has been found in association with adiposity and cardiovascular disease risk. In this paper, the objective was to assess the relationship of C-reactive protein to four anthropometric measurements: body mass index, waist-to-height ratio, C index, and waist cir...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2017.1338631
更新日期:2017-11-01 00:00:00
abstract::This paper describes relationships between reported alcohol consumption and selected sociodemographic and health variables. Two hundred and four men and 367 women aged 60-95 years were examined as part of a nutritional status survey of elderly. Fifty-three percent of men and 44% of women reported drinking at least 2 g...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1990.10720388
更新日期:1990-08-01 00:00:00
abstract::The glycemic index (GI) is a physiological assessment of a food's carbohydrate content through its effect on postprandial blood glucose concentrations. Evidence from trials and observational studies suggests that this physiological classification may have relevance to those chronic Western diseases associated with ove...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.2009.10718109
更新日期:2009-08-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1997.10718670
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:Our objective was to evaluate the effect of regular use of nutritional supplements on serum vitamin C levels in a multivariable regression model, taking into account other dietary and demographic variables which may affect nutritional status. METHODS:We analyzed NHANES II data for subjects age 3 to 74. Analy...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1994.10718367
更新日期:1994-02-01 00:00:00
abstract::Ingestion of fruit juices in which there is an imbalance between glucose and fructose (apple, pear nectar) and the presence of sorbitol is one of the major causes of the syndrome of chronic, nonspecific diarrhea of infancy and childhood. Stools in the condition at time of symptoms are acidic with a pH < 5.5, Clinitest...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1996.10720472
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:Magnesium deficiency and oxidative stress have both been identified as pathogenic factors in aging and in several age-related diseases. The link between these two factors is unclear in humans although, in experimental animals, severe Mg deficiency has been shown to lead to increased oxidative stress. METHODS...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2000.10718934
更新日期:2000-06-01 00:00:00
abstract::To study the role of diet as a risk factor for coronary heart disease (CHD), 463 adults (25-65 years, 419 males) at risk of or with CHD were assigned to group A (n = 231) receiving a cardiovasoprotective diet or group B (n = 232) receiving a normal diet in a randomized, single-blind fashion. Age, sex, risk factors and...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/07315724.1992.10718242
更新日期:1992-08-01 00:00:00
abstract::The vegetarian diet has been associated with lower blood pressure (BP) in elderly white Americans. This study was undertaken to determine whether or not long-term adherence (at least 5 years) to a plant-based diet is similarly related to lower BP in older black Americans, a group exhibiting significant risk for hypert...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1993.10718308
更新日期:1993-06-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/07315724.2005.10719438
更新日期:2005-02-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2012.10720434
更新日期:2012-10-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2004.10719339
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Neural tube defects (NTDs) are some of the most common congenital anomalies. Proper folic acid supplementation is a dominant risk factor, which has been shown to decrease the incidence of NTDs. In Canada, the incidence of neuroblastoma has presented a considerable decrease of 60% as a result of enrichment ce...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2008.10719731
更新日期:2008-08-01 00:00:00
abstract::Malnutrition has been often suggested as contributing to both the high incidence of hip fracture in elderly people and its complications. In a recent prospective controlled randomized study, the clinical outcome of elderly patients with osteoporotic fracture of the proximal femur (hip fracture) improved by giving a si...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/07315724.1992.10718256
更新日期:1992-10-01 00:00:00
abstract::A simple procedure has been developed for preparation of animal tissues and diet mixtures for Mg and Ca analysis by atomic absorption spectroscopy. This procedure involves wet ashing in warm 30% hydrogen peroxide and extraction of metals, from the dried ash, into cold, dilute nitric acid. Less than 200 mg of tissue or...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1983.10719920
更新日期:1983-01-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2010.10719852
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:NutriBee was the first clinical nutrition intervention designed to bring the Institute of Medicine recommendations for 20 hours of experiential nutrition-themed learning to grades 4-7 into club and camp settings. We piloted NutriBee to assess acceptability and impact among early adolescents in diverse and dis...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2015.1110507
更新日期:2016-07-01 00:00:00
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journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1991.10718161
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:To compare the effect of an experimental viscous fiber (VF) crispy bar on the postprandial glucose, insulin, and C-peptide response in adult subjects with type 2 diabetes to two commercially available control crispy bars. DESIGN:The study was a randomized, double-blinded, three period, crossover study. SETT...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1080/07315724.2006.10719553
更新日期:2006-10-01 00:00:00
abstract::To examine the relationship between zinc (Zn) status and bone demineralization, a body Zn kinetics study was performed with 74 (37 male, 37 female) disabled persons ranging in age from 16 to 45 years. Three groups were classified according to degree of limited mobility: group 1 (n = 23), capable of walking; group 2 (n...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1993.10718284
更新日期:1993-02-01 00:00:00
abstract::Coronary heart disease (CHD) is the leading cause of death in most developed nations and is rapidly increasing in prevalence in developing countries. Death rates from cardiovascular disease exceed 1 million annually in the United States and account for the largest disease-related cost to health with total costs estima...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,meta分析
doi:10.1080/07315724.2000.10718963
更新日期:2000-06-01 00:00:00
abstract::There is growing recognition of the value of changing tissue fatty acid patterns in their own right as coronary risk factors. To examine the effects of a conventional nutritional program on plasma triglyceride (TG), cholesterol ester, and phospholipid fatty acid patterns, a group of 20 hyperlipidemic men and a control...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1990.10720358
更新日期:1990-04-01 00:00:00
abstract::Human milk contains two lipases, bile salt-stimulated lipase (BSSL) and lipoprotein lipase (LPL). In the mammary gland, LPL provides long-chain fatty acid for milk fat synthesis. LPL has no known function in milk, but has been implicated in milk fat hydrolysis during cold storage. BSSL may have an important role in in...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1989.10720289
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:While not life threatening, muscle cramps severely affect the quality of life of patients with cirrhosis. AIM:To determine whether oral zinc sulfate therapy decreases the frequency and severity of muscle cramps in cirrhotic patients. METHODS:12 patients with cirrhosis (5 Child's A, 3 Child's B, and 4 Child...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章
doi:10.1080/07315724.2000.10718908
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:We studied the relationship between maternal and cord plasma concentrations of carotenoids, retinol, and tocopherols in normal mother-baby pairs. METHODS:Healthy pregnant women (n = 10) were recruited at a Montréal hospital. Venous blood samples were collected from the mothers at delivery and cord blood was ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1998.10718791
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:The salt (NaCl) content of bread, obtained from Belgium and 25 other regions or countries worldwide, was analyzed to evaluate the importance of bread as a source of dietary salt in a population. METHODS:A total of 1166 dried bread samples were analyzed using a hot HCl extraction technique followed by flame p...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1994.10718392
更新日期:1994-04-01 00:00:00
abstract:OBJECTIVE:This study evaluated the effect of cinnamon on disease activity, serum levels of some inflammatory markers, and cardiovascular risk factors in women with rheumatoid arthritis (RA). METHODS:In this randomized double-blind clinical trial, 36 women with RA were randomly divided to 2 groups, receiving 4 capsules...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2018.1460733
更新日期:2018-05-03 00:00:00