Abstract：
BACKGROUND:High sucrose intakes are hypothesized to increase colorectal cancer (CRC) risk by several mechanisms, and sucrose intakes have been consistently positively associated with CRC risk in case-control studies. However, all but one prospective study reported a null sucrose-CRC association. The only prospective study to report a positive association was the Iowa Women's Health Study (IWHS) of 35,221 cancer-free Iowa women, aged 55 - 69 years old at baseline in 1986, after four years of follow up. MATERIALS AND METHODS:To address the discrepant findings in the literature, after 26 years of follow up in the IWHS, we updated and expanded on our earlier reported analyses. During follow up through 2012, 1,731 women were diagnosed with CRC. Baseline dietary intakes were assessed with a Willett semiquantitative food frequency questionnaire. We used multivariable Cox proportional hazards regression models to estimate adjusted hazards ratios (HRs) and their 95% confidence intervals (CI). RESULTS:For those in the highest relative to the lowest intake quintiles, the adjusted HRs (95% CI) for CRC were 1.04 (0.87-1.23; Ptrend = 0.59) for sucrose, 1.00 (0.82-1.21; Ptrend = 0.67) for sucrose-containing foods, and 1.01, (0.83-1.22; Ptrend = 0.56) for nondairy sucrose-containing foods, respectively. These findings did not differ substantially by colorectal site or according to categories of selected participant characteristics. CONCLUSIONS:Our findings do not support that intakes of sucrose or sucrose-containing foods are substantially associated with CRC risk among older women.
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Kiran N,Prizment AE,Lazovich D,Mao Z,Bostick RMdoi
10.1080/07315724.2020.1848661subject
Has Abstractpub_date
2020-12-14 00:00:00pages
1-7eissn
0731-5724issn
1541-1087pub_type
杂志文章abstract：:To assess whether antioxidants may reduce the risk of cancer, we reviewed the epidemiologic literature from 1985 through 1993. We assessed the separate relationships of three antioxidants (carotenoids, vitamin C, and vitamin E) with six sites of cancer (lung, upper aerodigestive tract, uterine cervix, colon, breast, p...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1995.10718532
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:Nutritional status-related biological indexes were measured in fit, health-conscious elderly subjects in order to establish reference values for people over 70 years. SUBJECTS:103 men and 90 women aged 70-89 years living freely in the Paris area volunteered to participate. METHODS:Nutritional status was ass...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1994.10718461
更新日期：1994-12-01 00:00:00
abstract：:No single study or avenue of investigation can resolve the scientific controversies that entangle efforts to determine the effects of specific nutrients on medical conditions. To reach consensus in this area requires a substantial body of plausible, reproducible and consistent data from various investigative approache...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1999.10718904
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of an egg breakfast on lunchtime energy intake in children (age 4-6 years) and adolescents (age 14-17 years). METHODS:In 2 randomized crossover trials, participants received either an egg breakfast or an isocaloric bagel breakfast. In both trials, subsequent lunchtime energy intake wa...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2014.942471
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:Fatty acid profiles and desaturase (SCD-16, SCD018, D5D, D6D) and elongase (ELOVL6) enzyme activity have been associated with adiposity and metabolic disease. While this has been studied in adults, few studies have included children. The objective of this study was to evaluate these markers in children and i...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2017.1347908
更新日期：2018-01-01 00:00:00
abstract：:Approximately 3-4 million Americans experience food allergic reactions at some time in their lives. In the pediatric population, eggs and milk are most frequently implicated in food allergic reactions. The most well-understood adverse reactions to foods are secondary to the development of IgE antibodies to specific fo...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1990.10720399
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To compare the effect of an experimental viscous fiber (VF) crispy bar on the postprandial glucose, insulin, and C-peptide response in adult subjects with type 2 diabetes to two commercially available control crispy bars. DESIGN:The study was a randomized, double-blinded, three period, crossover study. SETT...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1080/07315724.2006.10719553
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:The present study evaluated the effects of repeated-sprint training in normobaric hypoxia and β-alanine supplementation (BA) on aerobic and anaerobic performance in recreationally active men. METHODS:Participants were randomly assigned to one of the following groups: normoxia/β-alanine (NB, n = 11), normoxia...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2018.1475269
更新日期：2019-02-01 00:00:00
abstract：:The impact of feeding a hypercaloric parenteral solution on N balance, energy metabolism, and muscle strength has been investigated in cachectic patients with gastrointestinal cancer and in malnourished patients without evidence of cancer (controls). Patients were examined during 5% dextrose administration (D5W) for 2...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.1989.10720323
更新日期：1989-12-01 00:00:00
abstract：:Resistance exercise is fundamentally anabolic and as such stimulates the process of skeletal muscle protein synthesis (MPS) in an absolute sense and relative to skeletal muscle protein breakdown (MPB). However, the net effect of resistance exercise is to shift net protein balance (NPB = MPS - MPB) to a more positive v...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2005.10719454
更新日期：2005-04-01 00:00:00
abstract：OBJECTIVE:Pelvic radiotherapy induces acute small bowel injury but its effects on nutritional status are unknown. The objective of this study was to prospectively evaluate nutritional, functional and morphologic intestinal changes, after radiotherapy. METHODS:Fifteen patients were studied before and after pelvic irrad...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2001.10719161
更新日期：2001-12-01 00:00:00
abstract：:Objective: To evaluate whether the Fat-to-Lean Mass (FyM) ratio is associated to hyperinsulinemia in healthy adolescents.Methods: Apparently healthy adolescents aged 10 to 15 years that according to sex, age, and percentiles of body fat percent, were included and allocated into the groups with elevated (body fat perce...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1752845
更新日期：2020-10-12 00:00:00
abstract：:America is experiencing a major obesity epidemic. The ramifications of this epidemic are immense since obesity is associated with chronic metabolic abnormalities such as insulin resistance, dyslipidemia, and heart disease. Reduced physical activity and/or increased energy intakes are important factors in this epidemic...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2005.10719460
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:The goal of this work is to assess the effect of L-carnitine on glucose disposal, particularly on insulin sensitivity, in healthy volunteers. METHODS:Fourteen healthy human volunteers were subjected to the intravenous glucose tolerance test (analyzed by means of the minimal model technique), together with in...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1999.10718866
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVE AND METHODS:We reviewed records of 41 children with treated phenylketonuria (PKU) in order to evaluate hematopoiesis and the effect of iron and protein sufficiency. RESULTS:Six children (15%) were found to have anemia. Combined depletion of iron and protein stores was most likely to result in anemia, and two...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2001.10719016
更新日期：2001-02-01 00:00:00
abstract：:Anorexia nervosa (AN) can result in extreme malnutrition, and these patients frequently require inordinately large amounts of calories to gain weight during refeeding therapy. Insulin-like growth factor-I (IGF-I) is a polypeptide that mediates many of the anabolic effects of growth hormone. Low levels of IGF-I have be...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1993.10718338
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:Aging health is associated with nutritional changes which are not well understood and were therefore evaluated in this study by comparing the nutritional status of centenarians and elderly (in their 70s) relative to young subjects. SUBJECTS:The participants were 27 young subjects (10 males, 17 females), 40 h...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1999.10718876
更新日期：1999-08-01 00:00:00
abstract：:Lutein and zeaxanthin are xanthophyll carotenoids found particularly in dark-green leafy vegetables and in egg yolks. They are widely distributed in tissues and are the principal carotenoids in the eye lens and macular region of the retina. Epidemiologic studies indicating an inverse relationship between xanthophyll i...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2004.10719427
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:Although some earlier studies have indicated an association between dietary/urinary sodium and bone mass density (BMD), bone mass content (BMC), and the risk of osteoporosis (OS), findings are still conflicting. The aim of this study was to summarize the relation of dietary/urinary sodium with BMD, BMC, and t...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,meta分析
doi：10.1080/07315724.2018.1431161
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:This study was designed to compare the metabolizable energy of two starch sources, standard cornstarch and high amylose cornstarch. METHODS:Diets containing 70% amylose (AM) or 70% amylopectin (AP) cornstarches were fed to 10 control and 14 hyperinsulinemic men for 14 weeks. During the last 4 weeks of each p...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1996.10718595
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To determine if a relationship exists between blood glucose control and variability in nutrient intake from day-to-day in subjects with type 1 diabetes. METHODS:Two three-day diet records and one measurement of glycated hemoglobin (HbA1c) were obtained from 272 subjects with type 1 diabetes treated with a mi...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1080/07315724.1999.10718858
更新日期：1999-06-01 00:00:00
abstract：:Dietary guidelines have broad implications for the health of individuals and populations. Increasingly, government agencies and medical organization that issue guidelines have pursued evidence-based approaches. These approaches emphasize a comprehensive, critical, and explicit examination of the scientific evidence th...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2006.10719578
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:This study was designed with two aims: 1) to determine if the coronary artery bypass graft (CABG) procedure alters plasma vitamin E and C concentrations of adult patients through repeated determinations of vitamin levels at time points before, during and following CABG, and 2) to assess whether plasma vitamin...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1998.10718742
更新日期：1998-04-01 00:00:00
abstract：:Respiratory function in mechanically ventilated patients (VP) is adversely affected by starvation and hypermetabolic stress. These patients are more successfully managed and extubated if proper nutritional support is provided. The features of metabolism and respiratory function in VP require moderation in glucose, fat...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1983.10719906
更新日期：1983-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine if the consumption of certain foods during the year prior to diagnosis of type 1 diabetes mellitus (T1D) was associated with the risk of developing T1D in children and youth residing in Prince Edward Island, Canada. METHODS:Cases (n = 57) consisted of newly diagno...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2008.10719719
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVES:Rheumatoid arthritis (RA) is an autoimmune disease characterized by an increase in some autoantibodies and proteolytic enzymes, leading to joint destruction. Although recent investigations have considered vitamin K as an anti-inflammatory nutrient with an important role in bone metabolism, there is currently...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2015.1026004
更新日期：2016-07-01 00:00:00
abstract：:Since there is evidence that fat distribution is a better predictor of cardiovascular disease than the degree of obesity, some risk factors for atherosclerosis have been evaluated in middle age Type II male diabetics and in obese subjects with and without glucose intolerance. In non-insulin-dependent diabetics (NIDD),...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1989.10720320
更新日期：1989-12-01 00:00:00
abstract：OBJECTIVE:Baseline characteristics of subjects might be related to the effect of plant stanols on the serum lipoprotein profile. The aim of the study was to examine effects of subjects' baseline characteristics (baseline serum concentrations of lipids and lipoproteins at the start of the study, lathosterol, campesterol...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2008.10719683
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:β-alanine (BA) is a nonproteogenic amino acid that combines with histidine to form carnosine. The amount taken orally in individual doses, however, is limited due to symptoms of paresthesia that are associated with higher doses. The use of a sustained-release formulation has been reported to reduce the sympto...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2017.1335250
更新日期：2017-11-01 00:00:00
abstract：:The glycemic index (GI) is a physiological assessment of a food's carbohydrate content through its effect on postprandial blood glucose concentrations. Evidence from trials and observational studies suggests that this physiological classification may have relevance to those chronic Western diseases associated with ove...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2009.10718109
更新日期：2009-08-01 00:00:00
