Modification of immunological potential by ultraviolet radiation. II. Generation of suppressor cells in short-term UV-irradiated mice.

abstract：BACKGROUND:Socioeconomic variables including low income and noncompliance impact negatively upon long-term renal allograft survival, especially in African Americans. We sought to determine whether other socioeconomic variables contributed to noncompliance and allograft survival. METHODS:A detailed history of socioecon...

journal_title：Transplantation

authors： Butkus DE,Dottes AL,Meydrech EF,Barber WH

更新日期：2001-07-27 00:00:00

abstract：:Lamivudine combined with hepatitis B immune globulin (HBIg) is the standard of care for preventing the recurrence hepatitis B virus after liver transplant. To determine the risk of hepatitis B virus (HBV) recurrence after early withdrawal of HBIg in patients receiving lamivudine maintenance therapy, 20 patients receiv...

journal_title：Transplantation

authors： Buti M,Mas A,Prieto M,Casafont F,González A,Miras M,Herrero JI,Jardi R,Esteban R

更新日期：2007-09-15 00:00:00

abstract：:Eradicating transplant tourism depends on complex solutions that include efforts to progress towards self-sufficiency in transplantation. Meanwhile, professionals and authorities are faced with medical, legal, and ethical problems raised by patients who return home after receiving an organ transplant abroad, particula...

journal_title：Transplantation

authors： Domínguez-Gil B,Danovitch G,Martin DE,López-Fraga M,Van Assche K,Morris ML,Lavee J,Erlich G,Fadhil R,Busic M,Rankin G,Al-Rukhaimi M,OʼConnell P,Chin J,Norman T,Massari P,Kamel R,Delmonico FL,Declaration of Istanbul Cu

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The terminal Gal alpha1,3Galactose (alphaGal) determinant is present on all porcine glycoproteins and glycolipids, but is not expressed by human cells. Consequently human sera contain anti-alphaGal natural antibodies. The human blood group B antigen [Gal alpha1,3(Fuc1,2)Galactose] is differentiated from the ...

journal_title：Transplantation

authors： McMorrow IM,Comrack CA,Nazarey PP,Sachs DH,DerSimonian H

更新日期：1997-08-15 00:00:00

abstract：:In light of the transplant community's efforts to increase living donation, preserving donor autonomy is essential. Understanding how often and the reasons why potential living kidney donors opt out of the donor evaluation process for nonmedical reasons is important for assessing donor voluntariness. The experiences o...

journal_title：Transplantation

authors： Thiessen C,Kulkarni S,Reese PP,Gordon EJ

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Several technical modifications in portal vein (PV) reconstruction have shown excellent outcomes in pediatric liver transplantation (LT); however, which procedure is the best for PV reconstruction of the hypoplastic PV in pediatric LT remains unclear. METHODS:One hundred sixteen pediatric patients aged 1 or...

journal_title：Transplantation

authors： Sakamoto S,Uchida H,Kitajima T,Shimizu S,Yoshimura S,Takeda M,Hirata Y,Fukuda A,Kasahara M

更新日期：2020-01-01 00:00:00

abstract：:Rejection crises after kidney transplantation could be associated with individual variability of pharmacokinetic parameters of steroids. We therefore investigated the individual pharmacokinetics of methylprednisolone on day 2 (60 mg intravenously) and day 4 (60 mg per os) in 40 patients after kidney transplantation. M...

journal_title：Transplantation

authors： Keller F,Hemmen T,Schöneshöfer M,Schwarz A,Offermann G

更新日期：1995-08-27 00:00:00

abstract：BACKGROUND:After pancreas transplantation, endocrine function is determined by the insulin secretory capacity of the transplanted pancreas. The authors evaluated the predictive value of postoperative oral glucose tolerance test (OGTT) and stimulated insulin secretion on long-term endocrine function. METHODS:Forty-one ...

journal_title：Transplantation

authors： Pfeffer F,Nauck MA,Drognitz O,Benz S,von Dobschuetz E,Hopt UT

更新日期：2003-11-27 00:00:00

abstract：:The purpose of this open-label, prospective study was to compare steady state concentrations and clearances of intravenously administered cyclosporine or tacrolimus with and without concomitant high-dose (400 mg/day) fluconazole in allogeneic BMT patients. Twenty-one patients were evaluable. The mean steady state cycl...

journal_title：Transplantation

authors： Osowski CL,Dix SP,Lin LS,Mullins RE,Geller RB,Wingard JR

更新日期：1996-04-27 00:00:00

abstract：BACKGROUND:Survival after lung transplantation is mainly limited by the development of chronic lung allograft dysfunction (CLAD). The aim of this study was to investigate if platelet inhibition by clopidogrel has a functionally relevant influence on the microvascular integrity of orthotopic tracheal allografts as an an...

journal_title：Transplantation

authors： Heim C,Khan MA,von Silva-Tarouca B,Kuckhahn A,Stamminger T,Ramsperger-Gleixner M,Nicolls MR,Weyand M,Ensminger SM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Langerhans cells (LCs) are self-renewing epidermal myeloid cells that can migrate and mature into dendritic cells. Recipient LCs that survive cytotoxic therapy given in preparation for allogeneic hematopoietic cell transplantation may prime donor T cells to mediate cutaneous graft-versus-host disease (GVHD)....

journal_title：Transplantation

authors： Mielcarek M,Kirkorian AY,Hackman RC,Price J,Storer BE,Wood BL,Leboeuf M,Bogunovic M,Storb R,Inamoto Y,Flowers ME,Martin PJ,Collin M,Merad M

更新日期：2014-09-15 00:00:00

abstract：:The use of cyclosporine has been associated with an increased incidence of thrombosis and endothelial cell perturbation. To explore possible mechanisms involved, we examined the effects of CSA on the activation of protein C by thrombomodulin. Cultured bovine aortic endothelial cell monolayers were incubated for 24 hr ...

journal_title：Transplantation

authors： Garcia-Maldonado M,Kaufman CE,Comp PC

更新日期：1991-03-01 00:00:00

abstract：:As a consequence of its large volume, a microencapsulated islet graft can be implanted only into the peritoneal cavity. The graft volume can be reduced by using small capsules. However, reduction of the diameter of the capsules holds a certain risk, because with smaller capsules, more islets may be found to protrude f...

journal_title：Transplantation

authors： De Vos P,De Haan B,Pater J,Van Schilfgaarde R

更新日期：1996-10-15 00:00:00

abstract：:The recent introduction of a variety of techniques for removing T cells from bone marrow grafts has reduced the incidence of graft-versus-host disease (GVHD)-associated morbidity and mortality. Whether this advance will be translated into improved patient survival is unclear at present, mainly because these procedures...

journal_title：Transplantation

authors： Bunjes D,Heit W,Arnold R,Schmeiser T,Wiesneth M,Carbonell F,Porzsolt F,Raghavachar A,Heimpel H

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Deoxyspergualin (DSG), a potent immunosuppressive drug, has been clinically used as a rescue therapy for acute graft rejection. However, DSG has severe adverse effects that limits its use. Here, we examined the optimized therapeutic protocol for DSG using chronopharmacological profiles of it. METHODS:First,...

journal_title：Transplantation

authors： Uchida H,Kobayashi E,Matsuda K,Mizuta K,Sugimoto K,Kawarasaki H,Hashizume K,Fujimura A

更新日期：1999-05-15 00:00:00

abstract：BACKGROUND:The delayed allograft rejection in C6-deficient PVG C6- rats compared with normal PVG rats has been attributed to the lack of alloantibody activation of the membrane attack complex of complement. As T cells alone have been shown to effect graft rejection, we examined T-cell responses in PVG C6- rats. METHOD...

journal_title：Transplantation

authors： Merten S,Chen JC,Ha H,Plain K,Boyd RA,Penny MJ,Leenaerts P,Hall BM

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:Infants (<12 months) who require liver transplantation (LTx) represent a particularly challenging and understudied group of patients. METHODS:This retrospective study aimed to describe a large single-center experience of infants who received isolated LTx, illustrate important differences in infants versus o...

journal_title：Transplantation

authors： Venick RS,Farmer DG,McDiarmid SV,Duffy JP,Gordon SA,Yersiz H,Hong JC,Vargas JH,Ament ME,Busuttil RW

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the population pharmacokinetics of tacrolimus in pediatric liver transplant recipients and to identify factors that may explain pharmacokinetic variability. METHODS:Data were collected retrospectively from 35 children who received oral immunosuppressant therapy with ...

journal_title：Transplantation

authors： Staatz CE,Taylor PJ,Lynch SV,Willis C,Charles BG,Tett SE

更新日期：2001-09-27 00:00:00

abstract：:With advances in microsurgery and molecular biology, the mouse model for organ transplantation has become increasingly popular. However, knowledge about these models is limited, as only a small number of centers have experience with murine models. In this study, we compared the rejection pattern after liver, kidney, h...

journal_title：Transplantation

authors： Zhang Z,Zhu L,Quan D,Garcia B,Ozcay N,Duff J,Stiller C,Lazarovits A,Grant D,Zhong R

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:Accurate and rapid diagnosis of human cytomegalovirus (HCMV) disease in solid organ transplant patients remains a challenge. We evaluated the clinical utility of a quantitative polymerase chain reaction (QPCR) method to diagnose transplant patients with HCMV disease. METHODS:A total of 429 plasma samples fr...

journal_title：Transplantation

authors： Ferreira-Gonzalez A,Fisher RA,Weymouth LA,Langley MR,Wolfe L,Wilkinson DS,Garrett CT

更新日期：1999-10-15 00:00:00

abstract：:The influence of continuous immunosuppression on the immune system of 2 neonates born to heart-lung transplant recipients was analyzed. T cells, T cell subpopulations, B cells and cyclosporine levels were measured in maternal and cord blood at the time of delivery. Cyclosporine, both parent compound, and metabolites w...

journal_title：Transplantation

authors： Rose ML,Dominguez M,Leaver N,Lachno R,Yacoub MH

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) after solid organ transplantation is rare, with only six AML cases after liver transplantation (LT) being reported. METHODS:Characteristics of three AML cases observed among 799 recipients of LT in the authors' institution and estimation of the standardized incidence ratio (SIR)...

journal_title：Transplantation

authors： Camós M,Esteve J,Rimola A,Grande L,Rozman M,Colomer D,Villamor N,Costa D,Montserrat E

更新日期：2004-01-27 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate purine nucleotide metabolism in peripheral blood mononuclear cells (PBMC) of cardiac transplant recipients switched from azathioprine to mycophenolate mofetil (MMF). METHODS:Concentrations of guanosine 5'triphosphate (GTP) and adenosine 5'triphosphate (ATP), th...

journal_title：Transplantation

authors： Devyatko E,Zuckermann A,Bohdjalian A,Roedler S,Dunkler D,Grimm M,Weigel G

更新日期：2006-07-15 00:00:00

abstract：:Posttransplant lymphoproliferative disorders (PTLD) are EBV-associated lymphoid neoplasms that are caused by the uncontrolled growth of EBV-infected B lymphocytes. The clinical presentation of PTLD can range from benign polygonal lymphoproliferative disorders to aggressive monoclonal immunoblastic lymphomas. In this r...

journal_title：Transplantation

authors： Mentzer SJ,Longtine J,Fingeroth J,Reilly JJ,DeCamp MM,O'Donnell W,Swanson SJ,Faller DV,Sugarbaker DJ

更新日期：1996-06-27 00:00:00

abstract：:The requirement for effective, minimally toxic immunosuppression remains a major obstacle to performing human composite tissue allotransplantation. The skin component of composite tissue (e.g., limb) allografts is especially antigenic, necessitating toxic immunosuppressant doses to prevent or reverse acute rejection. ...

journal_title：Transplantation

authors： van den Helder TB,Benhaim P,Anthony JP,McCalmont TH,Mathes SJ

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:A new vascularized concordant xenotransplant model using the Chinese hamster as donor and mouse as recipient species is reported. This model takes advantage of the wealth of informative immune reagents and knockout and transgenic backgrounds available for the mouse. METHODS:Heterotopic auxillary cardiac tra...

journal_title：Transplantation

authors： Obatake M,Kushida M,Kimmel S,Clarke ID,Kim PC

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:Immunosuppressive therapy is a risk factor for the increased incidence and metastatic progression of malignancies in organ graft recipients. Transforming growth factor (TGF)-beta(1) has been associated with tumor invasion and metastasis, and we have implicated cyclosporine-associated TGF-beta(1) hyperexpress...

journal_title：Transplantation

authors： Maluccio M,Sharma V,Lagman M,Vyas S,Yang H,Li B,Suthanthiran M

更新日期：2003-08-15 00:00:00

abstract：:The combination of pharmacokinetic and pharmacodynamic (measurement of the biological effect) monitoring of immunosuppressive drugs provides a method for the optimization of drug dosing. We chose to investigate this using mycophenolic acid (MPA), an immunosuppressive drug that mediates its effect by the inhibition of ...

journal_title：Transplantation

authors： Langman LJ,Shapiro AM,Lakey JR,LeGatt DF,Kneteman NM,Yatscoff RW

更新日期：1996-01-15 00:00:00

abstract：:Ninety-eight renal transplant recipients who had been followed for 1-6.5 years (median 3.2 years) were reviewed to determine the effect of donor and recipient hepatitis B surface antigen status on the incidence of hepatitis and on patient survival. The cumulative risk of developing hepatitis posttransplant was signifi...

journal_title：Transplantation

authors： Chan PC,Lok AS,Cheng IK,Chan MK

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Diarrhea is a frequent complication of solid organ transplantation. Cryptosporidiosis is classically reported in patients with acquired immunodeficiency syndrome and emerged as a cause of persistent diarrhea in solid organ transplant patients. METHODS:Through the ANOFEL Cryptosporidium National Network and ...

journal_title：Transplantation

authors： Lanternier F,Amazzough K,Favennec L,Mamzer-Bruneel MF,Abdoul H,Tourret J,Decramer S,Zuber J,Scemla A,Legendre C,Lortholary O,Bougnoux ME,ANOFEL Cryptosporidium National Network and Transplant Cryptosporidium Study Group.

更新日期：2017-04-01 00:00:00