Feasibility study of imaging a living murine tumor by electron paramagnetic resonance.

Abstract:

:An electron paramagnetic resonance image was measured for the first time from in vivo field gradient spectra of a living murine tumor (Cloudman S-91 melanoma in the tail of a DBA-2J mouse) using the paramagnetic nitroxide imaging agent 3-carboxamido-2,2,5,5-tetramethylpyrroline-1-oxyl injected into the tail vein. The experiments were accomplished at L-band frequency (1.55 GHz) with a single-turn flat-loop coil. A cross-sectional image was obtained perpendicular to the tail axis, which clearly distinguished features to the submillimeter resolution level.

journal_name

Magn Reson Med

authors

Berliner LJ,Fujii H,Wan XM,Lukiewicz SJ

doi

10.1002/mrm.1910040410

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

380-4

issue

4

eissn

0740-3194

issn

1522-2594

journal_volume

4

pub_type

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