Abstract:
:An electron paramagnetic resonance image was measured for the first time from in vivo field gradient spectra of a living murine tumor (Cloudman S-91 melanoma in the tail of a DBA-2J mouse) using the paramagnetic nitroxide imaging agent 3-carboxamido-2,2,5,5-tetramethylpyrroline-1-oxyl injected into the tail vein. The experiments were accomplished at L-band frequency (1.55 GHz) with a single-turn flat-loop coil. A cross-sectional image was obtained perpendicular to the tail axis, which clearly distinguished features to the submillimeter resolution level.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Berliner LJ,Fujii H,Wan XM,Lukiewicz SJdoi
10.1002/mrm.1910040410subject
Has Abstractpub_date
1987-04-01 00:00:00pages
380-4issue
4eissn
0740-3194issn
1522-2594journal_volume
4pub_type
杂志文章abstract:PURPOSE:To design short parallel transmission (pTx) pulses for excitation of arbitrary three-dimensional (3D) magnetization patterns. METHODS:We propose a joint optimization of the pTx radiofrequency (RF) and gradient waveforms for excitation of arbitrary 3D magnetization patterns. Our optimization of the gradient wav...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26021
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:To optimize 3D radial ultrashort echo time MRI for high resolution whole-lung imaging. METHODS:3D radial ultrashort echo time was implemented on a 3T scanner to investigate the effects of: (1) limited field-of-view excitation, (2) variable density readouts, and (3) radial oversampling. Improvements in noise pe...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24570
更新日期:2013-11-01 00:00:00
abstract::The clinical application of 3D proton spectroscopic imaging (3D SI) of the human prostate requires a robust suppression of periprostatic lipid signal contamination, minimal intervoxel signal contamination, and the shortest possible measurement time. In this work, a weighted elliptical sampling of k-space, combined wit...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20103
更新日期:2004-07-01 00:00:00
abstract::This study determines the accuracy and feasibility of using localized spin-lattice (T1) relaxation time measurements from magnetic resonance (MR) images to follow changes in extracellular/intracellular fluid ratios in defined subvolumes of living tissue. A red blood cell suspension was used as a test system and a simp...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910150107
更新日期:1990-07-01 00:00:00
abstract::Black blood MRI is an attractive tool for monitoring normal and pathological wall thickening; however, limited spatial resolutions can conspire with complex vascular geometries to distort the appearance of the wall in ways hitherto unclear. To elucidate this, a thin-walled cylinder model was developed to predict the c...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21758
更新日期:2008-11-01 00:00:00
abstract::In order to determine if an increase in myocardial oxygen consumption is accompanied by changes in high energy phosphates in normal subjects and patients with dilated cardiomyopathy, phosphorus-31 spectra were acquired under resting conditions and during dobutamine infusion. In seven normal subjects, dobutamine raised...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910250205
更新日期:1992-06-01 00:00:00
abstract:PURPOSE:Subendocardial dark-rim artifacts (DRAs) remain a major concern in first-pass perfusion (FPP) myocardial MRI and may lower the diagnostic accuracy for detection of ischemia. A major source of DRAs is the "Gibbs ringing" effect. We propose an optimized radial acquisition strategy aimed at eliminating ringing-ind...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24913
更新日期:2014-07-01 00:00:00
abstract::In echo-planar-based diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI), the evaluation of diffusion parameters such as apparent diffusion coefficients and anisotropy indices is affected by image distortions that arise from residual eddy currents produced by the diffusion-sensitizing gradients. Correc...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10690
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:Diffusion magnetic resonance imaging (MRI) microstructure imaging provides a unique noninvasive probe into tissue microstructure. The technique relies on biophysically motivated mathematical models, relating microscopic tissue features to the magnetic resonance (MR) signal. This work aims to determine which com...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25080
更新日期:2014-12-01 00:00:00
abstract::Human mesenchymal stem cells (hMSCs) were labeled with Ferucarbotran by simple incubation and cultured for up to 14 d. Iron content was determined by spectrometry and the intracellular localization of the contrast agent uptake was studied by electron and confocal microscopy. At various time points after labeling, rang...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22011
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:Develop and test an analytic correction method to correct the signal intensity variation caused by the inhomogeneous reception profile of an eight-channel phased array for hyperpolarized (13) C imaging. THEORY AND METHODS:Fiducial markers visible in anatomical images were attached to the individual coils to pr...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26042
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:To assess volumetric proton MR spectroscopic imaging (MRSI) of the human brain on multivendor MRI instruments. METHODS:Echo-planar spectroscopic imaging was developed on instruments from three manufacturers, with matched specifications and acquisition protocols that accounted for differences in sampling perfor...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25510
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To develop a new parallel transmit (pTx) pulse design for simultaneous multiband (MB) excitation in order to tackle simultaneously the problems of transmit B1 (B1+) inhomogeneity and total radiofrequency (RF) power, so as to allow for optimal RF excitation when using MB pulses for slice acceleration for high an...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24828
更新日期:2013-09-01 00:00:00
abstract::The recently developed technique of gradient, high-resolution magic-angle spinning NMR (g-hr-MAS-NMR) spectroscopy was applied to the study of ex vivo human lipoma and liposarcoma tissue. Compared with conventional 1H-NMR, the g-hr-MAS method yielded a large improvement in spectral resolution and permitted the detecti...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380307
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:Within multiple sclerosis (MS) lesions iron is present in chronically activated microglia. Thus, iron detection with MRI might provide a biomarker for chronic inflammation within lesions. Here, we examine contributions of iron and myelin to magnetic susceptibility of lesions on quantitative susceptibility mappi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25420
更新日期:2015-08-01 00:00:00
abstract::A non-invasive method for studying the modifications induced in lipid depots by hormonal stimulation could extend knowledge of adipose tissues. We studied the effect of adrenergic stimulation on interscapular brown adipose tissue (IBAT) of rats using contrast-enhanced MRI. Controls and rats pre-treated with adrenaline...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20851
更新日期:2006-04-01 00:00:00
abstract:PURPOSE:To develop a novel analytical method for quantification of chemical exchange saturation transfer (CEST) in the transient state. The proposed method aims to reduce the effects of non-chemical-exchange (non-CE) parameters on the CEST signal, emphasizing the effect of chemical exchange. METHODS:The difference in ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26559
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:The objective of this study was to determine whether a sodium phased array would improve sodium breast MRI at 3 T. The secondary objective was to create acceptable proton images with the sodium phased array in place. METHODS:A novel composite array for combined proton/sodium 3 T breast MRI is compared with a c...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24860
更新日期:2014-06-01 00:00:00
abstract::MR imaging experiments were conducted to investigate the feasibility of estimating vascular pulse pressure waveforms from measurements of blood flow rates and vessel cross-sectional area. Blood flow waveforms were measured in the aorta's of three 25-30-kg pigs at multiple imaging sections using phase-contrast velocity...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380209
更新日期:1997-08-01 00:00:00
abstract:PURPOSE:High-resolution intravascular (IV) MRI is susceptible to degradation from physiological motion and requires high frame-rates for true endoscopy. Traditional cardiac-gating techniques compromise efficiency by reducing the effective scan rate. Here we test whether compressed sensing (CS) reconstruction and ungate...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25436
更新日期:2015-08-01 00:00:00
abstract::Follow-up T(1)-weighted 3D gradient-echo MRI (2.35 T) of murine brain in vivo (N = 5) at 120 microm isotropic resolution revealed spatially distinct signal increases 6-48 hr after subcutaneous application of MnCl(2) (20 mg/kg). The effects result from a shortening of the water proton T(1) relaxation time due to the pr...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10276
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:High-resolution three-dimensional (3D) structural MRI is useful for delineating complex or small structures of the body. However, it requires long acquisition times and high SAR, limiting its clinical use. The purpose of this work is to accelerate the acquisition of high-resolution images by combining compresse...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27789
更新日期:2019-09-01 00:00:00
abstract::Current MRI methods for myocardial motion and strain quantification have limited resolution because of Fourier space spectral peak interference. Methods have been proposed to remove this interference in order to improve resolution; however, these methods are clinically impractical due to the prolonged imaging times. I...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22403
更新日期:2010-08-01 00:00:00
abstract::Localized 7Li MR point-resolved spectroscopy (PRESS) was developed as a technique to measure lithium (Li) concentration in rat brain in vivo. Localized 7Li spectra could be obtained at 4.7 T in a 0.7-ml voxel in rat brain over the entire therapeutic range of serum Li for humans. Localized 7Li spin-lattice (T1) and spi...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.20112
更新日期:2004-07-01 00:00:00
abstract::A birdcage coil possesses various intrinsic resonant modes. One of the modes produces sinusoidal current distribution around the rung elements of the birdcage and generates a highly uniform B(1) field in the transverse plane. Another mode is the end-ring resonant mode, in which there are no currents in the rungs of th...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/1522-2594(200010)44:4<633::aid-mrm18>3.0.c
更新日期:2000-10-01 00:00:00
abstract::A stereotaxic restraining assembly was designed and developed for simultaneous electrophysiological recordings and functional MRI (fMRI) data acquisition from a conscious rat. The design of the nonmagnetic stereotaxic apparatus facilitated the restraining of head and body of the unanesthetized conscious animal during ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.10441
更新日期:2003-05-01 00:00:00
abstract::The detection of free radical reactions in a gelatin sample irradiated by a heavy-ion beam was tested using electron paramagnetic resonance (EPR) spectroscopic and MRI methods. Geometry and the amount of free radical generation in a sample are described. A reaction mixture containing glutathione and a nitroxyl radical...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21958
更新日期:2009-05-01 00:00:00
abstract::Electron Spin Echo Envelope Modulation (ESEEM) data are reported for three gadolinium (III) chelates, Gd-EDTA, Gd-DTPA, and Gd-TTHA, in frozen D2O/CH3OD glasses. This series includes Gd-DTPA, an MRI contrast agent that is in clinical use. Three-pulse electron spin echo modulation patterns can be modeled to yield geome...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910290414
更新日期:1993-04-01 00:00:00
abstract::T(2) quantification may augment diagnostic T(2)-weighted imaging; to improve cancer detection via auto-segmentation of multi-parametric acquisitions and to potentiate longitudinal studies of prostate cancer. However, robust quantitative techniques are not generally accessible or refined for clinical translation. This ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22492
更新日期:2010-10-01 00:00:00
abstract::A 3.0 Tesla, 0.80-m bore magnet replaced our previous 1.9 Tesla, 0.76-m magnet. The 3.0 Tesla replacement magnet had a dipole moment of 1.7 with respect to that of the 1.9 Tesla magnet. The pre-existing cylindrically symmetric passive steel shielding was modified to confine the fringe fields of the replacement magnet ...
journal_title:Magnetic resonance in medicine
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doi:10.1002/mrm.1910290319
更新日期:1993-03-01 00:00:00