LncRNA H19/miR-194/PFTK1 axis modulates the cell proliferation and migration of pancreatic cancer.

abstract：:Follicle-stimulating hormone-follicle-stimulating hormone receptor (FSH-FSHR) interaction is one of the most thoroughly studied signaling pathways primarily because of being implicated in sexual reproduction in mammals by way of maintaining gonadal function and sexual fertility. Despite material advances in understand...

journal_title：Journal of cellular biochemistry

authors： Gharemirshamlu FR,Afsar M,Mokhdomi TA,Amin A,Bukhari S,Krishnan A,Kumar CV,Bamdad K,Patel TN,Qadri RA,Chikan NA,Shabir N

更新日期：2018-11-02 00:00:00

abstract：:The thermal denaturations of five revertant lambda repressors containing single amino acid substitutions in their N-terminal domains have been studied by differential scanning calorimetry. Two substitutions slightly decrease stability, and the remaining three render the protein more stable than wild type. The Gly48---...

journal_title：Journal of cellular biochemistry

authors： Hecht MH,Hehir KM,Nelson HC,Sturtevant JM,Sauer RT

更新日期：1985-01-01 00:00:00

abstract：:4-hydroxynonenal (HNE), a lipid peroxidation end product, is produced abundantly in osteoarthritic (OA) articular tissues and was recently identified as a potent catabolic factor in OA cartilage. In this study, we provide additional evidence that HNE acts as an inflammatory mediator by elucidating the signaling cascad...

journal_title：Journal of cellular biochemistry

authors： Vaillancourt F,Morquette B,Shi Q,Fahmi H,Lavigne P,Di Battista JA,Fernandes JC,Benderdour M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Gram-negative bacterium, Helicobacter pylori is notorious for various pathologies like peptic ulcers, gastritis, functional dyspepsia, and various cancers. METHODS:Systemic effects of its toxins have led scientists' attention toward the extragastric pathologies associated with it. To date, it has been shown...

journal_title：Journal of cellular biochemistry

authors： Zendehdel A,Roham M

更新日期：2019-08-01 00:00:00

abstract：:Erbb4-IR is a recently identified lncRNA with pivotal functions in renal injury. The present study investigated the roles of Erbb4-IR in esophageal squamous cell carcinoma (ESCC). It was observed that Erbb4-IR was upregulated in tumor tissues of patients with ESCC. Plasma levels of Erbb4-IR in patients with ESCC were ...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Zhang L,Wang R,Wang B,Hua P,Li J

更新日期：2019-10-01 00:00:00

abstract：:Mouse BC3H1 myogenic cells and a bi-functional chemical cross linking reagent were utilized to investigate the polymerization of newly-synthesized vascular smooth muscle (alpha-actin) and non-muscle (beta- and gamma-actin) actin monomers into native F-actin filament structures during myogenesis. Two actin dimer specie...

journal_title：Journal of cellular biochemistry

authors： Qu G,Yan H,Strauch AR

更新日期：1997-12-15 00:00:00

abstract：AIM:Oxymatrine (OMT) is the major quinolizidine alkaloid extracted from the root of Sophora flavescens Ait (the Chinese herb Kushen) and exhibits diverse pharmacological actions. In this study, we investigated the effects of OMT on diabetes-associated aortic endothelial dysfunction in a rat model of diabetes and its mec...

journal_title：Journal of cellular biochemistry

authors： Wang L,Li X,Zhang Y,Huang Y,Zhang Y,Ma Q

更新日期：2018-11-19 00:00:00

abstract：:Characteristic changes in vimentin were studied in 9L rat brain tumor cells treated at 45 degrees C. During heat-shock treatment, vimentin molecules were rapidly phosphorylated and reorganized from a filamentous form into a perinuclear higher-order structure that was less extractable by nonionic detergent. These effec...

journal_title：Journal of cellular biochemistry

authors： Cheng TJ,Lai YK

更新日期：1994-01-01 00:00:00

abstract：:Embryonic data and ultrastructural analyses suggest that the primitive endothelium signals undifferentiated mesenchymal cells to migrate to the forming blood vessel and subsequently regulates mural cell growth and behavior. Upon maturation of the blood vessel, chemotactic and mitogenic signals are apparently diminishe...

journal_title：Journal of cellular biochemistry

authors： Dodge AB,Lu X,D'Amore PA

更新日期：1993-09-01 00:00:00

abstract：:ZC3H12D belongs to a recently discovered family of proteins containing four members of which the most studied and best described is the RNase ZC3H12A (MCPIP1/Regnase-1). ZC3H12A is a crucial negative regulator of inflammation. It accelerates the turnover of transcripts of a spectrum of proinflammatory cytokines, as we...

journal_title：Journal of cellular biochemistry

authors： Wawro M,Kochan J,Krzanik S,Jura J,Kasza A

更新日期：2017-03-01 00:00:00

abstract：:Na+/D-glucose symport is a secondary active glucose transport mechanism expressed only in kidney proximal tubule and in small intestine. A monoclonal antibody that recognized the Na+/glucose symporter of pig renal brush border membranes also recognized a 75-kD protein in apical membranes isolated from highly different...

journal_title：Journal of cellular biochemistry

authors： Wu JS,Lever JE

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:The current study was designed to investigate the inhibitory effects of ginsenoside Rd (Gs-Rd) on human glioma U251 cells in vitro and its possible underlying mechanisms. METHODS:The groups included blank control group, low concentration Gs-Rd treatment group (20 μM), mid concentration Gs-Rd treatment group ...

journal_title：Journal of cellular biochemistry

authors： Gu B,Wang J,Song Y,Wang Q,Wu Q

更新日期：2019-03-01 00:00:00

abstract：:A chimeric long terminal repeat-thymidine kinase (LTR-tk) gene has been used to define the sequence requirements for glucocorticoid induction of gene expression. The original LTR-tk gene contains an entire mouse mammary tumor virus (MMTV) LTR preceding the tk gene. This gene can be expressed in a hormone-responsive fa...

journal_title：Journal of cellular biochemistry

authors： Groner B,Herrlich P,Kennedy N,Ponta H,Rahmsdorf U,Hynes NE

更新日期：1982-01-01 00:00:00

abstract：:1,25-dihydroxycholecalciferol (1,25(OH)2D3) possesses proliferation and differentiation modulating effects in many cell types in vitro. We studied the effect of 1,25(OH)2D3 on 3H-thymidine incorporation in FRTL5 cells, a cultured rat thyroid follicular cell line. 1,25(OH)2D3 alone at 10(-11) and 10(-9) M exerted no ef...

journal_title：Journal of cellular biochemistry

authors： Ongphiphadhanakul B,Ebner SA,Fang SL,Lombardi A,Baran DT,Braverman LE

更新日期：1992-07-01 00:00:00

abstract：:Accumulating evidence supports the role of miR-122 in fatty liver disease. We investigated miR-122 expression in a steatotic hepatocyte model, the effect of miR-122 over-expression and inhibition in the pathogenesis. Human hepatic cell line L02 was induced with oleic acid to establish the steatotic hepatocyte model. I...

journal_title：Journal of cellular biochemistry

authors： Nie YQ,Cao J,Zhou YJ,Liang X,Du YL,Wan YJ,Li YY

更新日期：2014-05-01 00:00:00

abstract：:We have a long-standing interest in a nuclear protease which appears to be involved in carcinogenesis. We recently identified the protease as high temperature requirement factor A 1 (HtrA1), also known as Prss11, which is member of an oxidative stress-response family of proteases. HtrA1 has been classified as a secret...

journal_title：Journal of cellular biochemistry

authors： Clawson GA,Bui V,Xin P,Wang N,Pan W

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis (OA) is a progressive and disabling disorder, characterized by synovial inflammation and joint effusion. This study aimed to explore the role of stanniocalcin-1 (STC1) in the development of OA by regulating the survival and inflammation of fibroblast-like synovial (FLS) cells. METHODS:Microarr...

journal_title：Journal of cellular biochemistry

authors： Wu Y,Li Z,Jia W,Li M,Tang M

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this study was to investigate ultrasound-triggered effects of the glial cell line-derived neurotrophic factor (GDNF) + nuclear receptor-related factor 1 (Nurr1)-polyethylene glycol (PEG)ylated liposomes-coupled microbubbles (PLs-GDNF + Nurr1-MBs) on behavioral impairment and neuron loss in a rat model o...

journal_title：Journal of cellular biochemistry

authors： Yue P,Gao L,Wang X,Ding X,Teng J

更新日期：2018-06-01 00:00:00

abstract：:In a previous work, taking advantage of the gene-array screening technology, we analysed the effects of histone deacetylase (HDAC) inhibitor sodium butyrate (NaBt), on gene transcription in HT29 human adenocarcinoma cell line. In this study, we focused our attention on p55CDC/Cdc20 gene, whose expression was dramatica...

journal_title：Journal of cellular biochemistry

authors： Iacomino G,Medici MC,Napoli D,Russo GL

更新日期：2006-11-01 00:00:00

abstract：:Previous studies have indicated that an increased inflammatory response plays an important role in preeclampsia (PE), and rising levels of interleukin (IL)-22 can trigger inflammation and hyperproliferation, leading to increased production of several pro-inflammatory cytokines such as IL-1, IL-6, and IL-8. We aimed to...

journal_title：Journal of cellular biochemistry

authors： Niu Z,Zhao X,Liu H,Quan J,Lin Y,Li J,Wang J,Liu M,Song W,Chen A,Liu S

更新日期：2018-06-01 00:00:00

abstract：:Cytology and cell biology are two separate fields that share a focus on cancer. Cancer is still diagnosed based on morphology, and surprisingly little is known about the molecular basis of the defining structural features. Cytology uses the smallest possible biopsy for diagnosis by reducing morphologic "criteria of ma...

journal_title：Journal of cellular biochemistry

authors： Fischer AH,Zhao C,Li QK,Gustafson KS,Eltoum IE,Tambouret R,Benstein B,Savaloja LC,Kulesza P

更新日期：2010-07-01 00:00:00

abstract：:Taxol, a microtubule stabilizing agent, has been extensively investigated for its antitumor activity. The cytotoxic effect of taxol is generally attributed to its antimicrotubule activity and is believed to be cell cycle dependent. Herein, we report that taxol induces hyperphosphorylation and reorganization of the vim...

journal_title：Journal of cellular biochemistry

authors： Chu JJ,Chen KD,Lin YL,Fei CY,Chiang AS,Chiang CD,Lai YK

更新日期：1998-03-15 00:00:00

abstract：:Multiple studies demonstrated that early growth response factor 1 (EGR1) induces myocardial damage after acute myocardial infarction (AMI). Recent evidence indicates that microRNAs (miRNA) play an important role in exosome-mediated cardioprotection after AMI. Bioinformatics analysis has shown that miR-146a can regulat...

journal_title：Journal of cellular biochemistry

authors： Pan J,Alimujiang M,Chen Q,Shi H,Luo X

更新日期：2019-03-01 00:00:00

abstract：:Lysozyme is expressed in serous, but not mucous, cells of the tracheobronchial glands and thereby constitutes a marker of the serous cell lineage in these glands. To identify DNA regulatory elements and transcription factors mediating the commitment of progenitor cells to the serous cell lineage, we have characterized...

journal_title：Journal of cellular biochemistry

authors： Kai H,Takeuchi K,Ohmori H,Li JD,Gallup M,Basbaum C

更新日期：1996-06-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a class of noncording RNAs that control gene expression by translational inhibition and messenger RNAs (mRNAs) degradation in plants and animals. Although miRNAs have been implicated in developmental and homeostatic events of vertebrates and invertebrates, the role of miRNAs in bone metabolism h...

journal_title：Journal of cellular biochemistry

authors： Sugatani T,Hruska KA

更新日期：2007-07-01 00:00:00

abstract：:Multiple sclerosis (MS) is a highly disabling demyelinating disease, which mainly affects young adults and is difficult to cure. Activated microglia may be involved in the process of neuronal cell damage and release inflammatory cytokines to injure neurons. Rapamycin (RAPA), an immunosuppressant, can induce autophagy ...

journal_title：Journal of cellular biochemistry

authors： Xu L,Zhang C,Jiang N,He D,Bai Y,Xin Y

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) has a high morbidity and mortality around the world, yet the effective therapeutic option for HCC is still limited. NPAC, also known as glyoxylate reductase 1 homolog, is a new nuclear protein recently implicated in tumor biology. However, the role of NPAC in HCC remains unclear...

journal_title：Journal of cellular biochemistry

authors： Zhang J,Sun N,Guo W,Wu X,Yang X,Jin H,Zhang Y,Wu X,Zhang F,Hu L,Hu H,Gao Y

更新日期：2018-11-26 00:00:00

abstract：:The miR-200c has recently been implicated in the epithelial to mesenchymal transition (EMT) process by directly target the EMT related transcriptional factors ZEB1 and ZEB2. The expression of this miRNA is inversely correlated with tumorgenecity and invasiveness in several human cancers. However, little is known about...

journal_title：Journal of cellular biochemistry

authors： Cui J,Cheng Y,Zhang P,Sun M,Gao F,Liu C,Cai J

更新日期：2014-06-01 00:00:00

abstract：:Ischemia/reperfusion injury is a tissue injury occurring post-reperfusion of tissues with pre-existing ischemia. A good blood supply to tissues aids in the survival of ischemic tissue, however, due to prolonged ischemia the levels of ATP decrease and pH declines leading to acidosis. Reduced ATP leads to an increase in...

journal_title：Journal of cellular biochemistry

authors： Ghaderi S,Alidadiani N,SoleimaniRad J,Heidari HR,Dilaver N,Heim C,Ramsperger-Gleixner M,Baradaran B,Weyand M

更新日期：2018-09-01 00:00:00

abstract：:Atherosclerosis and osteoporosis are the leading causes of mortality and morbidity in the World. Recent epidemiologic studies have demonstrated that these disease processes develop in parallel. Evidence indicates that hyperlipidemia plays a paradoxical role in both disease processes. However, the mechanism is not unde...

journal_title：Journal of cellular biochemistry

authors： Rajamannan NM

更新日期：2011-09-01 00:00:00