Developmentally regulated 75-kilodalton protein expressed in LLC-PK1 cultures is a component of the renal Na+/glucose cotransport system.

abstract：:The myelin basic protein (MBP)-phosphorylating enzymes present during maturation and early embryogenesis of the sea star (Pisaster ochraceus) were investigated. The major maturation-activated MBP kinase (p45 Mapk) was molecularly cloned based on tryptic sequence information obtained with the purified enzyme and shown ...

journal_title：Journal of cellular biochemistry

authors： Lefebvre DL,Charest DL,Yee A,Crawford BJ,Pelech SL

更新日期：1999-11-01 00:00:00

abstract：:This study aims to explore how microRNA-133a (miR-133a) affects cell apoptosis and radio-sensitivity by targeting EGFR via regulating MEK/ERK pathway in esophageal cancer (EC). A total of 358 EC patients were selected and assigned into the resistant and sensitive groups. Human EC KYSE 150 cell line was assigned into t...

journal_title：Journal of cellular biochemistry

authors： Yang QS,Jiang LP,He CY,Tong YN,Liu YY

更新日期：2017-09-01 00:00:00

abstract：:Arsenic is the first metal to be identified as a human carcinogen. Arsenite, one inorganic form of arsenic, has been found to induce sister chromatid exchange, chromosome aberrations, and gene amplification in a variety of in vitro systems. In this study of arsenite-induced genotoxicity represented a micronuclei produ...

journal_title：Journal of cellular biochemistry

authors： Liu YC,Huang H

更新日期：1997-03-01 00:00:00

abstract：:Magnolol, a substance purified from the bark of Magnolia officialis, inhibits cell proliferation and induces apoptosis in a variety of cancer cells. The aim of this study was to study the effects of magnolol on CGTH W-2 thyroid carcinoma cells. After 24 h treatment with 80 microM magnolol in serum-containing medium, a...

journal_title：Journal of cellular biochemistry

authors： Huang SH,Chen Y,Tung PY,Wu JC,Chen KH,Wu JM,Wang SM

更新日期：2007-07-01 00:00:00

abstract：:Although, the precise host defence mechanism(s) is not completely understood, T cell-mediated immune responses is believed to play a pivotal role in controlling parasite infection. Here we target the stage dependent over expressed gene. Here, the consensus based computational approach was adopted for the screening of ...

journal_title：Journal of cellular biochemistry

authors： Dikhit MR,Vijayamahantesh.,Kumar A,Amit A,Dehury B,Nathsharma YP,Ansari MY,Ali V,Topno RK,Das V,Pandey K,Sahoo GC,Bimal S,Das P

更新日期：2018-01-01 00:00:00

abstract：:Common differentially expressed genes (DEGs) in acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) might play critical roles in the pathogenesis and process of leukemia. We collected RNA sequencing (RNA-seq) data of human CLL, ALL samples, and normal peripheral blood CD19+ B cells as well as thy...

journal_title：Journal of cellular biochemistry

authors： Zhang S,Zhang Q,Yin J,Wu X

更新日期：2019-09-01 00:00:00

abstract：:Reduced insulin receptor protein levels have been reported in the kidney cortex from diabetic humans and animals. We recently reported that, targeted deletion of insulin receptor (IR) from proximal tubules (PT) resulted in hyperglycemia in non-obese mice. To elucidate the mechanism, we examined human proximal tubule c...

journal_title：Journal of cellular biochemistry

authors： Pandey G,Shankar K,Makhija E,Gaikwad A,Ecelbarger C,Mandhani A,Srivastava A,Tiwari S

更新日期：2017-02-01 00:00:00

abstract：:Albuminuria is indicative of nephropathy. However, little literature has focused on the role of albumin in renal distal tubule fibrosis. We used a well-defined distal tubule cell, Madin-Darby Canine Kidney (MDCK). Proliferation and cytotoxicity were examined. The conditioned supernatant was collected and subjected to ...

journal_title：Journal of cellular biochemistry

authors： Liu HC,Liao TN,Lee TC,Chuang LY,Guh JY,Liu SF,Hu MS,Yang YL,Lin SH,Hung MY,Huang JS,Hung TJ,Chen CD,Chiang TA,Chan JY,Chen SY,Yang YL

更新日期：2006-04-01 00:00:00

abstract：:Alkaptonuria (AKU) is a rare genetic disease associated with the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products in connective tissues up to the deposition of melanin-like pigments (ochronosis). Since little is known on the effects of HGA and its metabolites on articular cells, we carried...

journal_title：Journal of cellular biochemistry

authors： Braconi D,Laschi M,Taylor AM,Bernardini G,Spreafico A,Tinti L,Gallagher JA,Santucci A

更新日期：2010-11-01 00:00:00

abstract：:Primary cultures fill a unique niche among the repertoire of in vitro model systems available to investigate the biology of the normal and malignant human prostate. This review summarizes some of the properties of primary cultures, with special emphasis on two questions: are primary cultures from adenocarcinomas reall...

journal_title：Journal of cellular biochemistry

authors： Peehl DM

更新日期：2004-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) have been identified as key players in cardiogenesis and heart pathophysiological processes. However, many miRNAs are still not recognized for their roles in cardiomyocytes differentiation. In this study, we evaluated the effects of microRNA-218 (miR-218) in cardiomyocyte differentiation of the mous...

journal_title：Journal of cellular biochemistry

authors： Xu T,Liu N,Shao Y,Huang Y,Zhu D

更新日期：2019-03-01 00:00:00

abstract：:ATF6, a 670 amino acid endoplasmic reticulum (ER) transmembrane glycoprotein with the electrophoretic mobility of a 90 kDa protein, is a key transcriptional activator of the unfolded protein response (UPR) that allows mammalian cells to maintain cellular homeostasis when the cells are subjected to a variety of environ...

journal_title：Journal of cellular biochemistry

authors： Hong M,Li M,Mao C,Lee AS

更新日期：2004-07-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) are linked to tumor development and progression. The aim of this study was to determine the prognostic significance and biological role of LINC01116 in head and neck squamous cell carcinoma (HNSCC). We identified 21 aberrantly expressed lncRNAs specific to HNSCC that were common in two mi...

journal_title：Journal of cellular biochemistry

authors： Wu J,Chen Z,Zhang L,Cao J,Li X,Gong Z,Bo H,Zhang S,He D

更新日期：2020-01-01 00:00:00

abstract：:Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer-related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its functions as an important role in various biological functions through the epigenetic regulation of gene transcription. However, the oncogenic effect...

journal_title：Journal of cellular biochemistry

authors： Sun W,Guo F,Liu M

更新日期：2018-04-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:This study aimed to address the insufficiency of traditional meta-analysis and provide improved guidelines for the clinical practice of osteosarcoma treatment. The heterogeneity of the fixed-effect model was calculated, and when necessary, a random-effect model was adopted. Furthermore, the direct and indirect evidenc...

journal_title：Journal of cellular biochemistry

authors： Zhang T,Zhang S,Yang F,Wang L,Zhu S,Qiu B,Li S,Deng Z

更新日期：2018-01-01 00:00:00

abstract：:Cutaneous melanoma (CM) has become a major public health concern. Studies illustrate that minichromosome maintenance protein 7 (MCM7) participate in various diseases including skin disease. Our study aimed to study the effects of MCM7 silencing on CM cell autophagy and apoptosis by modulating the AKT threonine kinase ...

journal_title：Journal of cellular biochemistry

authors： Yang Y,Ma S,Ye Z,Zhou X

更新日期：2020-02-01 00:00:00

abstract：:Pancreatic-cancer-patient tumor specimens were initially established subcutaneously in NOD/SCID mice immediately after surgery. The patient tumors were then harvested from NOD/SCID mice and passaged orthotopically in transgenic nude mice ubiquitously expressing red fluorescent protein (RFP). The primary patient tumors...

journal_title：Journal of cellular biochemistry

authors： Suetsugu A,Katz M,Fleming J,Truty M,Thomas R,Moriwaki H,Bouvet M,Saji S,Hoffman RM

更新日期：2012-07-01 00:00:00

abstract：:The cardiomyocyte (CM) differentiation of embryonic stem cells (ESCs) is routinely cultured as two-dimensional (2D) monolayer, which doesn't mimic in vivo physiological environment and may lead to low differentiated level of ESCs. Here, we develop a novel strategy that enhances CM differentiation of ESCs in collagen m...

journal_title：Journal of cellular biochemistry

authors： Ou DB,He Y,Chen R,Teng JW,Wang HT,Zeng D,Liu XT,Ding L,Huang JY,Zheng QS

更新日期：2011-12-01 00:00:00

abstract：:Phosphoproteins produced by the incubation of crude extracts of Salmonella typhimurium and Escherichia coli with either [32P]phosphoenolpyruvate or [gamma 32P]ATP have been resolved and detected using sodium dodecyl sulphate polyacrylamide gel electrophoresis and autoradiography. Simple techniques were found such that...

journal_title：Journal of cellular biochemistry

authors： Waygood EB,Mattoo RL,Peri KG

更新日期：1984-01-01 00:00:00

abstract：:AIMP1 was first found as a factor associated with the aminoacyl-tRNA synthetase (ARS) complex. However, it is also secreted and acts on different target cells such as endothelial cells, macrophages, and fibroblasts as an extracellular regulator, respectively, of angiogenesis, inflammatory responses and dermal regenera...

journal_title：Journal of cellular biochemistry

authors： Jackson VC,Dewilde S,Albo AG,Lis K,Corpillo D,Canepa B

更新日期：2011-07-01 00:00:00

abstract：:The three ingredients for the successful tissue engineering of bone and cartilage are regulatory signals, cells, and extracellular matrix. Recent advances in cellular and molecular biology of the growth and differentiation factors have set the stage for a symbiosis of biotechnology and biomaterials. Recent advances pe...

journal_title：Journal of cellular biochemistry

authors： Reddi AH

更新日期：1994-10-01 00:00:00

abstract：:Mouse strains which develop tumors at a high incidence with characteristics very similar to human cancers have been derived over the last 8 years. The tumors are caused by defined genetic alterations in the mouse genome. Three areas of research have contributed to the derivation of these mouse strains: (1) Molecular a...

journal_title：Journal of cellular biochemistry

authors： Groner B

更新日期：1992-06-01 00:00:00

abstract：:The role of beta-catenin in skeletal development and osteogenic cell differentiation is well established, but the molecular mechanisms attending these effects remain largely unknown. We conducted a structure/function analysis of beta-catenin to gain further insights on these mechanisms. Retroviral transduction of a fu...

journal_title：Journal of cellular biochemistry

authors： Salazar VS,Mbalaviele G,Civitelli R

更新日期：2008-06-01 00:00:00

abstract：:Peptidylarginine deiminase is localized in the cytosol of the luminal and glandular epithelia of the nonpregnant murine uterus and its expression is regulated by sex hormones [Takahara et al., [1989]: J Biol Chem 264, 13361-13368; Takahara et al. [1992]: J Biol Chem 267,520-525]. Here, we demonstrate that changes occu...

journal_title：Journal of cellular biochemistry

authors： Arai T,Kusubata M,Kohsaka T,Shiraiwa M,Sugawara K,Takahara H

更新日期：1995-07-01 00:00:00

abstract：:A chimeric long terminal repeat-thymidine kinase (LTR-tk) gene has been used to define the sequence requirements for glucocorticoid induction of gene expression. The original LTR-tk gene contains an entire mouse mammary tumor virus (MMTV) LTR preceding the tk gene. This gene can be expressed in a hormone-responsive fa...

journal_title：Journal of cellular biochemistry

authors： Groner B,Herrlich P,Kennedy N,Ponta H,Rahmsdorf U,Hynes NE

更新日期：1982-01-01 00:00:00

abstract：:Recent studies have shown that only breast cancer epithelial cells with intact p53 can induce metallothionein (MT) synthesis after exposure to metals. In this study, the potential role of p53 on regulation of MT was investigated. Results demonstrate that zinc and copper increased metal response elements (MREs) activit...

journal_title：Journal of cellular biochemistry

authors： Ostrakhovitch EA,Olsson PE,von Hofsten J,Cherian MG

更新日期：2007-12-15 00:00:00

abstract：:This study aimed to identify differential circular RNA (circRNA) in the plasma exosomes of patients with lung adenocarcinoma (LUAD) using high-throughput sequencing. First, exosomes were isolated using an exosome isolation kit and confirmed by Western blotting, transmission electron microscopy, and NanoSight Assay. Su...

journal_title：Journal of cellular biochemistry

authors： Chen F,Huang C,Wu Q,Jiang L,Chen S,Chen L

更新日期：2020-03-01 00:00:00

abstract：:The present study investigates the direct action of 5-methoxytryptophol (5-MTX) in both MC3T3-E1 and RAW264.7 cells and compares it with melatonin (MEL), another 5-methoxyindol known to play a significant role on bone metabolism. We first screened increasing doses of both 5-MTX and MEL to determine their effect on met...

journal_title：Journal of cellular biochemistry

authors： Satué M,Ramis JM,del Mar Arriero M,Monjo M

更新日期：2015-04-01 00:00:00

abstract：:The stimulation of cultured guinea pig alveolar macrophages by the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine, or by the phospholipid inflammatory mediator platelet activating factor (PAF) induced an increase in arachidonic acid release and its cyclooxygenase products. This release, which was mi...

journal_title：Journal of cellular biochemistry

authors： Kadiri C,Masliah J,Bachelet M,Vargaftig BB,Béréziat G

更新日期：1989-06-01 00:00:00