Three-dimensional co-culture facilitates the differentiation of embryonic stem cells into mature cardiomyocytes.

abstract：:A panel of monoclonal antibodies and conventional antisera directed against desmosomal proteins from bovine muzzle epidermis was used to identify immunologically related proteins from two other bovine stratified squamous epithelia, cornea and esophagus. Desmosome-enriched tissue fractions were prepared from epidermis,...

journal_title：Journal of cellular biochemistry

authors： Giudice GJ,Cohen SM,Patel NH,Steinberg MS

更新日期：1984-01-01 00:00:00

abstract：:Fluorescent proteins have enabled the color-coding of cells growing in vivo. Noninvasive imaging of cells expressing fluorescent proteins has allowed the real-time determination of the behavior of cancer cells, the progression of infection, the differentiation of stem cells, and interaction of stromal and cancer cells...

journal_title：Journal of cellular biochemistry

authors： Hoffman RM

更新日期：2017-09-01 00:00:00

abstract：AIM:Oxymatrine (OMT) is the major quinolizidine alkaloid extracted from the root of Sophora flavescens Ait (the Chinese herb Kushen) and exhibits diverse pharmacological actions. In this study, we investigated the effects of OMT on diabetes-associated aortic endothelial dysfunction in a rat model of diabetes and its mec...

journal_title：Journal of cellular biochemistry

authors： Wang L,Li X,Zhang Y,Huang Y,Zhang Y,Ma Q

更新日期：2018-11-19 00:00:00

abstract：:Vitamin D is one of the oldest hormones that have been made in the earliest life forms for over 750 million years. Phytoplankton, zooplankton, and most plants and animals that are exposed to sunlight have the capacity to make vitamin D. Vitamin D is critically important for the development, growth, and maintenance of ...

journal_title：Journal of cellular biochemistry

authors： Holick MF

更新日期：2003-02-01 00:00:00

abstract：:Osteosarcoma (OS) is a highly aggressive bone tumor with a poor prognosis. MicroRNAs are revealed to exerts essential roles in the carcinogenesis and tumor invasion of OS. But, the function of miR-1296-5p and its related mechanism in OS progression have not yet been studied. This study discovered the levels of miR-129...

journal_title：Journal of cellular biochemistry

authors： Wang L,Hu K,Chao Y,Wang X

更新日期：2020-02-01 00:00:00

abstract：:Rearrangement of cell-cell adhesion is a critical event in embryonic development and tissue formation. We investigated the regulatory function of E-cadherin, a key adhesion protein, in the developmental process by using E-cadherin/IgG Fc fusion protein as an adhesion matrix in cell culture. F9 embryonal carcinoma cell...

journal_title：Journal of cellular biochemistry

authors： Nagaoka M,Ise H,Harada I,Koshimizu U,Maruyama A,Akaike T

更新日期：2008-01-01 00:00:00

abstract：:Cisplatin (DDP)-based chemotherapy is a standard strategy for ovarian cancer (OC), while chemoresistance remains a major therapeutic challenge. Transcription factor SOX9 has been reported to be associated with tumor cell proliferation, metastasis, and chemoresistance. In the current study, we observed a higher SOX9 ex...

journal_title：Journal of cellular biochemistry

authors： Xiao S,Li Y,Pan Q,Ye M,He S,Tian Q,Xue M

更新日期：2019-03-01 00:00:00

abstract：:Vascularization is essential for bone development, fracture healing, and bone tissue engineering. We have previously described that coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves differentiation of both cell types. Investigating the role of microRNAs (miRNAs)...

journal_title：Journal of cellular biochemistry

authors： Strassburg S,Nabar N,Lampert F,Goerke SM,Pfeifer D,Finkenzeller G,Stark GB,Simunovic F

更新日期：2017-07-01 00:00:00

abstract：:Our previous studies have shown that vanadium, a dietary micronutrient, has an inhibitory effect against experimentally induced rat hepatocarcinogenesis. In this study, we evaluated the role of vanadium on some potential protein expression markers of carcinogenesis, such as metallothionein (MT), an intracellular metal...

journal_title：Journal of cellular biochemistry

authors： Chakraborty T,Samanta S,Ghosh B,Thirumoorthy N,Chatterjee M

更新日期：2005-03-01 00:00:00

abstract：:P-selectin glycoprotein ligand-1 (PSGL-1) is the best-characterized selectin ligand that has been demonstrated to mediate leukocytes rolling on endothelium and leukocytes recruitment into inflamed tissue in vivo. In addition to its direct role in leukocyte capturing, PSGL-1 also functions as a signal-transducing recep...

journal_title：Journal of cellular biochemistry

authors： Ba X,Chen C,Gao Y,Zeng X

更新日期：2005-02-01 00:00:00

abstract：:Apoptosis has been described extensively in tooth development, which is under tight control of multiple apoptosis regulators, including anti-apoptotic protein Bcl-2. However, it is totally unclear how Bcl-2 is related to odontogenesis, especially dentinogenesis. Using a transgenic mouse Col2.3Bcl-2 in which human Bcl-...

journal_title：Journal of cellular biochemistry

authors： Zhang W,Ju J,Gronowicz G

更新日期：2010-10-01 00:00:00

abstract：:Vascular pathologies induced by ischemia/reperfusion involve the production of reactive oxygen species (ROS) that in part cause tissue injury. The production of ROS that occurs upon reperfusion activates specific second messenger pathways. In diabetic retinopathy there is a characteristic loss of the microvascular per...

journal_title：Journal of cellular biochemistry

authors： Shojaee N,Patton WF,Hechtman HB,Shepro D

更新日期：1999-10-01 00:00:00

abstract：:We examined the action of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on HeLa cells and compared it with that of cisplatin (CP). MNNG directly killed a substantial number of cells within 1 hour and resulted in strong DNA-damage as evidenced by Comet measurements. Despite appearance of DNA lesions, p53 protein was not ...

journal_title：Journal of cellular biochemistry

authors： Wesierska-Gadek J,Gueorguieva M,Schloffer D,Uhl M,Wojciechowski J

更新日期：2003-08-15 00:00:00

abstract：:Embryonic data and ultrastructural analyses suggest that the primitive endothelium signals undifferentiated mesenchymal cells to migrate to the forming blood vessel and subsequently regulates mural cell growth and behavior. Upon maturation of the blood vessel, chemotactic and mitogenic signals are apparently diminishe...

journal_title：Journal of cellular biochemistry

authors： Dodge AB,Lu X,D'Amore PA

更新日期：1993-09-01 00:00:00

abstract：:CD133 and CD44 are commonly used markers of cancer stem cells (CSCs), which are characterized by their ability for self-renewal and tumorigenicity. However, the clinical value and significance of CD133 and CD44 in lung metastasis of osteosarcoma (OS) remains controversial. The purpose of this study was to investigate ...

journal_title：Journal of cellular biochemistry

authors： He A,Yang X,Huang Y,Feng T,Wang Y,Sun Y,Shen Z,Yao Y

更新日期：2015-08-01 00:00:00

abstract：:Generation of osteoblasts from human somatic cells may be applicable in an effective transplantation therapy against bone diseases. Recently we established a procedure to directly convert human fibroblasts into osteoblasts by transducing some transcription factor genes via retroviral vectors. However, retroviral vecto...

journal_title：Journal of cellular biochemistry

authors： Yamamoto K,Sato Y,Honjo K,Ichioka H,Oseko F,Sowa Y,Yamamoto T,Kanamura N,Kishida T,Mazda O

更新日期：2016-11-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:Skeletal muscle atrophy is a well-known adverse effect of chronic treatment with glucocorticoids and it also occurs when stress conditions such as sepsis and cachexia increase the release of endogenous glucocorticoids. Although the mechanisms of action of these hormones have been elucidated, the possible molecular mec...

journal_title：Journal of cellular biochemistry

authors： Massaccesi L,Goi G,Tringali C,Barassi A,Venerando B,Papini N

更新日期：2016-08-01 00:00:00

abstract：:Plasminogen activator inhibitor type-1 (PAI-1) is the major negative regulator of the plasmin-dependent pericellular proteolytic cascade. PAI-1 gene expression is normally growth state regulated but frequently elevated in chronic fibroproliferative and neoplastic diseases affecting both stromal restructuring and cellu...

journal_title：Journal of cellular biochemistry

authors： Qi L,Allen RR,Lu Q,Higgins CE,Garone R,Staiano-Coico L,Higgins PJ

更新日期：2006-10-01 00:00:00

abstract：:In this report, we describe a human immunodeficiency virus type-1 (HIV-1)-infected promyelocytic cell line, OM, derived from HL-60 cells. Although the OM cell line was biologically cloned twice, the pattern of HIV-1 expression during culture appeared analogous to a classical acute spreading infection and was inhibited...

journal_title：Journal of cellular biochemistry

authors： Butera ST,Perez VL,Besansky NJ,Chan WC,Wu BY,Nabel GJ,Folks TM

更新日期：1991-04-01 00:00:00

abstract：:Melanoma skin cancer is one of the main causes of male cancer-related deaths worldwide. It has been suggested that miR-330-5p can act as a tumor suppressor in various types of cancers. So, in this study, we replaced miR-330 in melanoma cancer cells by vector-based miR-330 to evaluate the effects of this microRNA on th...

journal_title：Journal of cellular biochemistry

authors： Sehati N,Sadeghie N,Mansoori B,Mohammadi A,Shanehbandi D,Baradaran B

更新日期：2020-01-01 00:00:00

abstract：:Wip1 belongs to the protein phosphatase C (PP2C) family, of which expression is up-regulated by a number of external stresses, and serves as a stress modulator in normal physiological conditions. When overexpressed, premature dephosphorylation of stress-mediators by Wip1 results in abrogation of tumor surveillance, th...

journal_title：Journal of cellular biochemistry

authors： Jeong HC,Gil NY,Lee HS,Cho SJ,Kim K,Chun KH,Cho H,Cha HJ

更新日期：2015-08-01 00:00:00

abstract：:Serpentine receptors coupled to the heterotrimeric G protein, Gi2, are capable of stimulating DNA synthesis in a variety of cell types. A common feature of the Gi2-coupled stimulation of DNA synthesis is the activation of the mitogen-activated protein kinases (MAPKs). The regulation of MAPK activation by the Gi2-coupl...

journal_title：Journal of cellular biochemistry

authors： Johnson GL,Gardner AM,Lange-Carter C,Qian NX,Russell M,Winitz S

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:Endometrial carcinoma (EC), a common gynecological malignancy with high incidence, affects the mental and physical health of women. Mounting evidence shows that long noncoding RNAs (lncRNAs), messenger RNAs (mRNAs), and microRNAs (miRNAs) have instrumental roles in various biological processes associated with t...

journal_title：Journal of cellular biochemistry

authors： Zhao D,Ren C,Yao Y,Wang Q,Li F,Li Y,Jiang A,Wang G

更新日期：2020-03-01 00:00:00

abstract：:Cellular life-span of neonatal human brain microvascular endotheliocytes (HBME) was estimated by population doubling levels (PDLs) for serial subcultivations until spontaneous proliferation stoppage, and was 2.4-fold longer for continuous administration with the 6-O-phosphorylated derivative (TocP) of alpha-tocopherol...

journal_title：Journal of cellular biochemistry

authors： Tanaka Y,Moritoh Y,Miwa N

更新日期：2007-10-15 00:00:00

abstract：:Renal 11beta-hydroxysteroid dehydrogenase 2 (HSD2) catalyzes the conversion of active glucocorticoids to inert 11beta-keto compounds, thereby preventing the illicit binding of these hormones to mineralocorticoid receptors (MRs) and, thus, conferring aldosterone specificity. Absence or inhibition of HSD2 activity, orig...

journal_title：Journal of cellular biochemistry

authors： Zallocchi ML,Matkovic L,Calvo JC,Damasco MC

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The impact of aberrant expression of miRNAs, small noncoding RNAs of 19 to 23 nucleotide, has been reported in different types of cancer, such as breast cancer. Authors aim to investigate the role of circulating miRNA-335 as a diagnostic and prognostic marker for breast cancer. MATERIALS AND METHODS:miRNA-3...

journal_title：Journal of cellular biochemistry

authors： Swellam M,Mahmoud MS,Hashim M,Hassan NM,Sobeih ME,Nageeb AM

更新日期：2019-06-01 00:00:00

abstract：:Interleukin-1 (IL-1)alpha is an autocrine/paracrine agent of the skeletal tissue and it regulates bone remodeling. Collagenase-3 or matrix metalloproteinase (MMP)-13 is expressed in osteoblasts and its expression is modulated by several cytokines including IL-1alpha. Because the molecular mechanism of increased synthe...

journal_title：Journal of cellular biochemistry

authors： Varghese S,Canalis E

更新日期：2003-12-01 00:00:00

abstract：:The identification and purification of murine multipotent mesenchymal stem cells (MSCs) have been difficult due to their low frequency, the presence of contaminating cell types and lack of unambiguous markers. Using a magnetic micro-beads negative selection technique to remove hematopoietic cells from mouse bone marro...

journal_title：Journal of cellular biochemistry

authors： McKenzie KP,Mayer DC,Aubin JE

更新日期：2013-05-01 00:00:00

abstract：:A gene coding for the (pro)phospholipase A2 (PLA2) from bovine pancreas has been designed, synthesized, and expressed in Escherichia coli. The gene was designed with a variety of restriction sites that will facilitate future mutagenesis studies. Codons occurring frequently in prokaryotic systems were chosen whenever p...

journal_title：Journal of cellular biochemistry

authors： Noel JP,Tsai MD

更新日期：1989-07-01 00:00:00