Knockdown of LINC01116 inhibits cell migration and invasion in head and neck squamous cell carcinoma through epithelial-mesenchymal transition pathway.

abstract：:Long noncoding RNAs (lncRNAs) areinvolvedin a variety of biological processes. In silkworm, numerous lncRNAs have been predicted through deep transcriptome sequencing, but no functional role has been experimentally validated yet. Here, we characterized a new lncRNA iab-1 that was mainly encoded by the intergenic regio...

journal_title：Journal of cellular biochemistry

authors： Wang H,Hu H,Xiang Z,Lu C,Dai F,Tong X

更新日期：2019-10-01 00:00:00

abstract：:The BRCA1 tumor suppressor involved in breast and ovarian cancer is linked to several fundamental cell regulatory processes. Recently, it was reported that BRCA1 supports localization of XIST RNA to the inactive X chromosome (Xi) in women. The apparent cytological overlap between BRCA1 and XIST RNA across the Xi raise...

journal_title：Journal of cellular biochemistry

authors： Pageau GJ,Hall LL,Lawrence JB

更新日期：2007-03-01 00:00:00

abstract：:This study aims to explore the effects of shRNA-mediated silencing on Pyruvate kinase type M2 (PKM2) gene during aerobic glycolysis in colorectal cancer (CRC) cells. CRC tissues and adjacent normal tissues were obtained from 136 patients diagnosed with qRT-PCR, Western blotting, and immunohistochemistry (IHC) were per...

journal_title：Journal of cellular biochemistry

authors： Yan XL,Zhang XB,Ao R,Guan L

更新日期：2017-12-01 00:00:00

abstract：:The cleavage of poliovirus precursor polypeptides occurs at specific amino acid pairs that are recognized by viral proteinases. Most of the polio-specific cleavages occur at glutamine-glycine (Q-G) pairs that are recognized by the viral-encoded proteinase 3C (formerly called P3-7c). In order to carry out a defined mol...

journal_title：Journal of cellular biochemistry

authors： Semler BL,Johnson VH,Dewalt PG,Ypma-Wong MF

更新日期：1987-01-01 00:00:00

abstract：:Berberine (BBR) is an isoquinoline alkaloid derived from various medicinal herbs. Previous studies have suggested that BBR exerts antimicrobial, antitumor, and antidiabetic effects and can be used to treat Helicobacter pylori-induced chronic gastritis. However, the exact mechanism by which BBR inhibits H. pylori infec...

journal_title：Journal of cellular biochemistry

authors： Wu X,Li X,Dang Z,Jia Y

更新日期：2018-07-01 00:00:00

abstract：:Monoclonal antibodies that bind a large molecular weight plasma membrane protein of Acanthamoeba castellanii cause the cells to differentiate. A different monoclonal antibody that binds specifically to the major plasma membrane protein has no effect upon cell division or differentiation. The induction of differentiati...

journal_title：Journal of cellular biochemistry

authors： Villemez CL,Carlo PL,Russell MA

更新日期：1985-01-01 00:00:00

abstract：:Growing evidence has shown that a large number of miRNAs are abnormally expressed in cervical cancer (CC) tissues and play irreplaceable roles in tumorigenesis, progression, and metastasis. This study aimed to identify new biomarkers and pivotal genes associated with CC prognosis through comprehensive bioinformatics a...

journal_title：Journal of cellular biochemistry

authors： Gao C,Zhou C,Zhuang J,Liu L,Liu C,Li H,Liu G,Wei J,Sun C

更新日期：2018-08-01 00:00:00

abstract：:Na+/D-glucose symport is a secondary active glucose transport mechanism expressed only in kidney proximal tubule and in small intestine. A monoclonal antibody that recognized the Na+/glucose symporter of pig renal brush border membranes also recognized a 75-kD protein in apical membranes isolated from highly different...

journal_title：Journal of cellular biochemistry

authors： Wu JS,Lever JE

更新日期：1989-05-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are involved in a variety of physiological and pathological processes. We analyzed 11 data sets from Gene Expression Omnibus Database and found that MMP7 and MMP15 were highly expressed in multiple carcinomas. GSE13204 showed that MMP7 and MM...

journal_title：Journal of cellular biochemistry

authors： Wu Y,Pan S,Leng J,Xie T,Jamal M,Yin Q,Li J,He C,Dong X,Shao L,Zhang Q

更新日期：2019-06-01 00:00:00

abstract：:D-Glucose serves many roles in cellular functions, but its role in human periodontal ligament-derived mesenchymal stem cells (hPSLSCs) is yet unknown. Here, the roles of high glucose concentration on neurogenic differentiation by hPDLSCs were investigated. Two-stage neurogenic induction protocol was employed. Cells we...

journal_title：Journal of cellular biochemistry

authors： Sawangmake C,Pavasant P,Chansiripornchai P,Osathanon T

更新日期：2014-05-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:Withangulatin A induced cell rounding up and the morphological alteration resulted from the reorganization of all of the major cytoskeletal components, i.e., vimentin, tubulin, and actin, as revealed by immunofluorescence techniques. When the withangulatin A-treated cells changed to a round-up morphology, vimentin int...

journal_title：Journal of cellular biochemistry

authors： Lee WC,Lee YC,Perng MD,Chen CM,Lai YK

更新日期：1993-07-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) SM protein is a member of a highly conserved family of proteins present in most mammalian herpes viruses. There is a significant amount of functional and sequence divergence among the homologs encoded by the human herpes viruses, including differences in mechanism of action and varying eff...

journal_title：Journal of cellular biochemistry

authors： Swaminathan S

更新日期：2005-07-01 00:00:00

abstract：:The epigenetics and molecular biology of human embryonic stem cells (hES cells) have received much more attention than their architecture. We present a more complete look at hES cells by electron microscopy, with a special emphasis on the architecture of the nucleus. We propose that there is an ultrastructural signatu...

journal_title：Journal of cellular biochemistry

authors： Underwood JM,Becker KA,Stein GS,Nickerson JA

更新日期：2017-04-01 00:00:00

abstract：:CD133 and CD44 are commonly used markers of cancer stem cells (CSCs), which are characterized by their ability for self-renewal and tumorigenicity. However, the clinical value and significance of CD133 and CD44 in lung metastasis of osteosarcoma (OS) remains controversial. The purpose of this study was to investigate ...

journal_title：Journal of cellular biochemistry

authors： He A,Yang X,Huang Y,Feng T,Wang Y,Sun Y,Shen Z,Yao Y

更新日期：2015-08-01 00:00:00

abstract：:Mounting evidence showed that microRNAs involve in development and chemoresistance of various human cancers. We explored the roles and mechanisms of miR-144 in resistance to cisplatin (CDDP) of cervical cancer cells. miR-144 and LIM homeobox 2 (LHX2) expression in CDDP-resistant and the parental cells was determined b...

journal_title：Journal of cellular biochemistry

authors： Shi F,Su J,Liu Z,Wang J,Wang T

更新日期：2019-09-01 00:00:00

abstract：:The CRISPR-Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR-Cas-based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR-Cas platform along with lateral flow system allows rapid, sensitive, spe...

journal_title：Journal of cellular biochemistry

authors： Khambhati K,Bhattacharjee G,Singh V

更新日期：2019-03-01 00:00:00

abstract：:Obesity is associated with a state of chronic, low-grade inflammation. It is considered that the paracrine loop involving free fatty acid (FFA) and tumor necrosis factor (TNF)α between adipocytes and macrophages establishes an inflammatory vicious cycle that augments the inflammatory changes and insulin resistance in ...

journal_title：Journal of cellular biochemistry

authors： Jiang B,Qiao J,Yang Y,Lu Y

更新日期：2012-08-01 00:00:00

abstract：:Pancreatic-cancer-patient tumor specimens were initially established subcutaneously in NOD/SCID mice immediately after surgery. The patient tumors were then harvested from NOD/SCID mice and passaged orthotopically in transgenic nude mice ubiquitously expressing red fluorescent protein (RFP). The primary patient tumors...

journal_title：Journal of cellular biochemistry

authors： Suetsugu A,Katz M,Fleming J,Truty M,Thomas R,Moriwaki H,Bouvet M,Saji S,Hoffman RM

更新日期：2012-07-01 00:00:00

abstract：:Ceruloplasmin (CP) is essential for brain iron homeostasis. However, its precise function in brain iron transport has not been definitely determined. In this study, we investigated the effects of soluble CP on iron influx and efflux in primary neuronal culture from the midbrain (the substantia nigra and striatum) and ...

journal_title：Journal of cellular biochemistry

authors： Ke Y,Ho K,Du J,Zhu L,Xu Y,Wang Q,Wang CY,Li L,Ge X,Chang Y,Qian ZM

更新日期：2006-07-01 00:00:00

abstract：:The role of TatD DNases as DNA repair enzymes or cell death (apoptotic) nucleases is well established in prokaryotes as well as eukaryotes. The current study aims to characterize the TatD nuclease from Bacillus anthracis (Ba TatD) and to explore its key histidine catalytic residues. Ba TatD was found to be a metal-dep...

journal_title：Journal of cellular biochemistry

authors： Singh D,Rahi A,Kumari R,Gupta V,Gautam G,Aggarwal S,Rehan M,Bhatnagar R

更新日期：2019-02-05 00:00:00

abstract：:There has been an impressive emergence of mass spectrometry based technologies applied toward the study of proteins. Equally notable is the rapid adaptation of these technologies to biomedical approaches in the realm of clinical proteomics. Concerted efforts toward the elucidation of the proteomes of organ sites or sp...

journal_title：Journal of cellular biochemistry

authors： Semmes OJ,Malik G,Ward M

更新日期：2006-06-01 00:00:00

abstract：:Osteoprotegerin (OPG) is a decoy receptor for receptor activator of NF-kappaB ligand (RANKL) and TNF-related apoptosis-inducing ligand (TRAIL). While RANKL is essential for osteoclastogenesis and facilitates breast cancer migration into bone, TRAIL promotes breast cancer apoptosis. We analyzed the expression of OPG an...

journal_title：Journal of cellular biochemistry

authors： Rachner TD,Benad P,Rauner M,Goettsch C,Singh SK,Schoppet M,Hofbauer LC

更新日期：2009-09-01 00:00:00

abstract：:The ERK-MAPK signaling pathway plays a pivotal role during mesenchymal stem cell (MSC) differentiation. Studies have demonstrated that ERK-MAPK promotes adipogenesis and osteogenesis through the phosphorylation of differentiation-associated transcription factors and that it is the only active signaling in all three li...

journal_title：Journal of cellular biochemistry

authors： Mei Y,Bian C,Li J,Du Z,Zhou H,Yang Z,Zhao RC

更新日期：2013-06-01 00:00:00

abstract：:Macromolecules are sulfated during the vegetative growth of Dictyostelium discoideum. A characterisation of the structures of sulfated oligosaccharides associated with these macromolecules indicates that the oligosaccharides are heterogeneous. Endoglycosidase and pronase digestion were used with gel-filtration chromat...

journal_title：Journal of cellular biochemistry

authors： Davis SJ

更新日期：1988-10-01 00:00:00

abstract：:We have compared the cytotoxic/cytostatic responses of the SKW6.4 lymphoblastoid B-cells to the alkylating agent chlorambucil, the purine analog fludarabine, the non-genotoxic activator of the p53 pathway, Nutlin-3, used alone or in association with the death-inducing ligand recombinant TRAIL. Exposure to chlorambucil...

journal_title：Journal of cellular biochemistry

authors： Barbarotto E,Corallini F,Rimondi E,Fadda R,Mischiati C,Grill V,Vaccarezza M,Celeghini C

更新日期：2008-05-15 00:00:00

abstract：:Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervo...

journal_title：Journal of cellular biochemistry

authors： Fukushima N

更新日期：2004-08-01 00:00:00

abstract：:The activity of S6 kinases (S6K) is highly induced in cancer cells highlighting an essential role in carcinogenesis. The S6K family has two members: S6K1 and S6K2 which bear common as well as distinct features. In an attempt to identify S6K2 unique sequence features compared to S6K1, we applied extensive bioinformatic...

journal_title：Journal of cellular biochemistry

authors： Ismail HM,Hurd PJ,Khalil MI,Kouzarides T,Bannister A,Gout I

更新日期：2014-06-01 00:00:00

abstract：:Cleft palate is one of the most common birth defects. Several environment factors are involved in the disorder, such as smoking, vitamin deficiency and teratogens. We investigated the teratogenic agent phenytoin and extract of the immunostimulant Echinacea purpurea in the etiology of cleft palate associated with the p...

journal_title：Journal of cellular biochemistry

authors： Hu X,Chen Z,Mao X,Tang S

更新日期：2011-05-01 00:00:00

abstract：:The migration of endothelial cells (ECs) plays an important role in vascular remodeling and regeneration. EC migration can be regulated by different mechanisms such as chemotaxis, haptotaxis, and mechanotaxis. This review will focus on fluid shear stress-induced mechanotransduction during EC migration. EC migration an...

journal_title：Journal of cellular biochemistry

authors： Li S,Huang NF,Hsu S

更新日期：2005-12-15 00:00:00