Mouse uterus peptidylarginine deiminase is expressed in decidual cells during pregnancy.

abstract：:A key step in human colon cancer development includes the hyperactivation of Wnt/beta-catenin signaling and the induction of beta-catenin-TCF target genes that participate in colon cancer progression. Recent studies identified members of the immunoglobulin-like cell adhesion molecules (IgCAM) of the L1CAM family (L1 a...

journal_title：Journal of cellular biochemistry

authors： Raveh S,Gavert N,Spiegel I,Ben-Ze'ev A

更新日期：2009-09-01 00:00:00

abstract：:The phenotypic modulation of VSMCs is a key cellular event driving neointimal formation and vascular remodeling. As a multifaceted cytokine of cell-mediated immunity, IFN-γ has been shown to play a critical role in the pathogenesis of vascular proliferative diseases. Although the important function of IFN-γ on regulat...

journal_title：Journal of cellular biochemistry

authors： Wang K,Li W,Yu Q,Guo B,Yang B,Zhang C,Li M,Li J,Hu S,Zheng Q,Song Z

更新日期：2017-03-01 00:00:00

abstract：:D-Glucose serves many roles in cellular functions, but its role in human periodontal ligament-derived mesenchymal stem cells (hPSLSCs) is yet unknown. Here, the roles of high glucose concentration on neurogenic differentiation by hPDLSCs were investigated. Two-stage neurogenic induction protocol was employed. Cells we...

journal_title：Journal of cellular biochemistry

authors： Sawangmake C,Pavasant P,Chansiripornchai P,Osathanon T

更新日期：2014-05-01 00:00:00

abstract：:Hypoxia inducible factor 1α (HIF-1α), an essential transcriptional factor, is negatively regulated by two different types of oxygen and Fe(2+) -dependent HIF hydroxylases, proline hydroxylase (PHD) and factor inhibiting HIF (FIH), under normoxia. Iron chelators have therefore been used for inducing HIF-1α expression b...

journal_title：Journal of cellular biochemistry

authors： Cho EA,Song HK,Lee SH,Chung BH,Lim HM,Lee MK

更新日期：2013-04-01 00:00:00

abstract：:Photodynamic therapy (PDT) employing methyl δ-aminolevulinic acid (Me-ALA), as a precursor of the photosensitizer protoporphyrin IX (PpIX), is used for the treatment of non melanoma cutaneous cancer (NMCC). However, one of the problems of PDT is the apparition of resistant cell populations. The aim of this study was t...

journal_title：Journal of cellular biochemistry

authors： Milla LN,Cogno IS,Rodríguez ME,Sanz-Rodríguez F,Zamarrón A,Gilaberte Y,Carrasco E,Rivarola VA,Juarranz A

更新日期：2011-09-01 00:00:00

abstract：:We have previously demonstrated the direct involvement of a type 1 Ser/Thr phosphatase (PPase 1) in endothelial cell (EC) barrier regulation [Am. J. Physiol. 269:L99-L108, 1995]. To further extend this observation, we microinjected either the Ser/Thr PPase inhibitor, calyculin, or the PPase 1 inhibitory protein, I-2 i...

journal_title：Journal of cellular biochemistry

authors： Verin AD,Csortos C,Durbin SD,Aydanyan A,Wang P,Patterson CE,Garcia JG

更新日期：2000-07-19 00:00:00

abstract：:RECK is an anti-tumoral gene whose activity has been associated with its inhibitory effects regulating MMP-2, MMP-9, and MT1-MMP. RECK level decreases as gliobastoma progresses, varying from less invasive grade II gliomas to very invasive human glioblastoma multiforme (GBM). Since RECK expression and glioma invasivene...

journal_title：Journal of cellular biochemistry

authors： Silveira Corrêa TC,Massaro RR,Brohem CA,Taboga SR,Lamers ML,Santos MF,Maria-Engler SS

更新日期：2010-05-01 00:00:00

abstract：:TNF-a is an important cytokine mediator of inflammation which suggests that inhibition of TNF activity may provide potential for clinical application. Recent data indicated that treatment of both human and mouse cells with Kavain significantly modulates P. gingivalis- and LPS-induced TNF-α expression. In order to obta...

journal_title：Journal of cellular biochemistry

authors： Tang X,Alasiri M,Bamashmous A,Aljahdali B,Cao F,Dibart S,Salih E

更新日期：2018-07-01 00:00:00

abstract：:Adult human mesenchymal stem cells (MSCs) hold promise for an increasing list of therapeutic uses due to their ease of isolation, expansion, and multi-lineage differentiation potential. To maximize the clinical potential of MSCs, the underlying mechanisms by which MSC functionality is controlled must be understood. We...

journal_title：Journal of cellular biochemistry

authors： Pricola KL,Kuhn NZ,Haleem-Smith H,Song Y,Tuan RS

更新日期：2009-10-15 00:00:00

abstract：:Phosphatidylethanolamine-binding protein 4 (PEBP4), a member of the PEBP family, has been reported to play a pivotal role in tumor progression. However, its role in epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells remains unclear. Here, we investigated the effects and underlying m...

journal_title：Journal of cellular biochemistry

authors： Jian W,Bai Y,Li X,Kang J,Lei Y,Xue Y

更新日期：2019-04-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00

abstract：:Allele-specific transcription is a characteristic feature of imprinted genes. Many imprinted genes are also transcribed in a tissue- or cell type-specific manner. Overlapping epigenetic signals must, therefore, modulate allele-specific and tissue-specific expression at imprinted loci. In addition, long-range interacti...

journal_title：Journal of cellular biochemistry

authors： Hanel ML,Lau JC,Paradis I,Drouin R,Wevrick R

更新日期：2005-04-01 00:00:00

abstract：:In order to assess, in a controlled in vitro model, the differentiation potential of adult bone marrow derived stem cells we have developed a coculture procedure using adult rat cardiomyocytes and mesenchymal stem cells (MSCs) from transgenic GFP positive rats. We investigated in the cocultured MSCs the time course of...

journal_title：Journal of cellular biochemistry

authors： Gallo MP,Ramella R,Alloatti G,Penna C,Pagliaro P,Marcantoni A,Bonafé F,Losano G,Levi R

更新日期：2007-01-01 00:00:00

abstract：:The role of insulin-like growth factor-I (IGF-I) in regulating estrogen receptor-alpha (ER-alpha) gene expression and activity was investigated in the human breast cancer cell line MCF-7. Treatment of cells with 40 ng/ml IGF-I resulted in a 60% decrease in ER-alpha protein concentration by 3 h, and the amount of ER-al...

journal_title：Journal of cellular biochemistry

authors： Stoica A,Saceda M,Fakhro A,Joyner M,Martin MB

更新日期：2000-01-01 00:00:00

abstract：:This study investigated the protein kinase C (PKC) and matrix metalloproteinase-2 (MMP-2) in the development of deciduomata in pseudo-pregnant and pregnant rats. The results showed that the expression of MMP-2 was significantly increased from day 2 to day 5 in pseudo-pregnancy and from day 7 to day 9 in pregnancy. To ...

journal_title：Journal of cellular biochemistry

authors： Tsai JH,Hwang JM,Ying TH,Shyu JC,Tsai CC,Hsieh YS,Wang YW,Liu JY,Kao SH

更新日期：2009-10-15 00:00:00

abstract：:The higher ordered structure of the chicken alpha 2(1) procollagen gene was analyzed in chromatin isolated from expressing (lung) and nonexpressing (reticulocyte and erythrocyte) tissues. Digestion of DNA with methylation sensitive restriction endonucleases revealed that this gene was methylated in all tissues examine...

journal_title：Journal of cellular biochemistry

authors： Truter SL,Parker MI

更新日期：1994-02-01 00:00:00

abstract：:NELL-1 (Nel-like molecule-1) is a secreted osteogenic growth factor first identified in human craniosynostosis (CS) patients. NELL-1 protein has been observed to promote bone and cartilage differentiation and to suppress adipogenesis in both in vitro and in vivo models. Despite these findings, the cell surface recepto...

journal_title：Journal of cellular biochemistry

authors： Shen J,James AW,Chung J,Lee K,Zhang JB,Ho S,Lee KS,Kim TM,Niimi T,Kuroda S,Ting K,Soo C

更新日期：2012-12-01 00:00:00

abstract：:Acid-electrolyzed functional water (FW) is obtained through the electrolysis of sodium chloride solution. Stimulation of the human fibroblastic cell line HeLa by FW led to the augmented secretion of basic fibroblast growth factor (bFGF). Immunoprecipitation followed by Western blot analysis revealed that both high and...

journal_title：Journal of cellular biochemistry

authors： Motozawa K,Motoyoshi M,Saiki A,Sasaki H,Shimizu N,Asano M

更新日期：2018-09-01 00:00:00

abstract：:Decreased translation initiation adversely impacts protein synthesis and contributes to the myocardial dysfunction produced by sepsis. Therefore, the purpose of the present study was to identify sepsis-induced changes in signal transduction pathways known to regulate translation initiation in cardiac muscle and to det...

journal_title：Journal of cellular biochemistry

authors： Lang CH,Pruznak AM,Frost RA

更新日期：2005-02-01 00:00:00

abstract：:Adamts17 is a member of a family of secreted metalloproteinases. In this report, we show that knockdown of Adamts17 expression induces apoptosis and inhibits breast cancer cell growth. Adamts17 expression can rapidly be induced by estrogens. siRNA knockdown of Sp1 or Myc demonstrated that Sp1 is required to induce Ada...

journal_title：Journal of cellular biochemistry

authors： Jia Z,Gao S,M'Rabet N,De Geyter C,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:Colorectal cancer (CRC) brings more than 600 000 deaths every year around the globe, making itself the third most frequently occurred carcinoma. The great progress human achieved in diagnosis and treatment of various cancers has failed to reverse this trend. Fortunately, growing evidence has implied the relationship b...

journal_title：Journal of cellular biochemistry

authors： Cui G,Zhao H,Li L

更新日期：2020-10-01 00:00:00

abstract：:Chemotherapy drug resistance frequently happens in more than 50% of bladder cancer patients and is the major obstacle for the bladder cancer therapy. Recent studies have shown that long noncoding RNA (lncRNA) is involved in the development of chemoresistance. In this study, we reported hypoxia inducible factor 1α-anti...

journal_title：Journal of cellular biochemistry

authors： Chen X,Liu M,Meng F,Sun B,Jin X,Jia C

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Curcuminoids are polyphenols with documented anti-inflammatory activity and has been shown to improve the symptoms of several inflammatory diseases. We aimed to evaluate the effectiveness of a nanoformulation of curcuminoids in the treatment of ulcerative colitis. METHODS:This randomized double-blinded cont...

journal_title：Journal of cellular biochemistry

authors： Masoodi M,Mahdiabadi MA,Mokhtare M,Agah S,Kashani AHF,Rezadoost AM,Sabzikarian M,Talebi A,Sahebkar A

更新日期：2018-11-01 00:00:00

abstract：:O-linked N-acetylglucosamine (O-GlcNAc) glycosylation is a post-translational modification, which is believed antagonises phosphorylation. We have studied the O-GlcNAc level during Xenopus oocyte meiotic resumption, taking advantage of the high synchrony of this model which is dependent upon a burst of phosphorylation...

journal_title：Journal of cellular biochemistry

authors： Lefebvre T,Baert F,Bodart JF,Flament S,Michalski JC,Vilain JP

更新日期：2004-11-15 00:00:00

abstract：:AT-rich interaction domain 4A (ARID4A) and AT-rich interaction domain 4B (ARID4B), which are both the AT-rich interaction domain (ARID) family, have been reported to be oncogene or tumor suppressor gene in various human malignances, but there is no involvement about their functions in prostate cancer (PCa). Our previo...

journal_title：Journal of cellular biochemistry

authors： Liang YK,Han ZD,Lu JM,Liu ZZ,Zhuo YJ,Zhu XJ,Chen JX,Ye JH,Liang YX,He HC,Zhong WD

更新日期：2018-09-01 00:00:00

abstract：:Vitamin D is one of the oldest hormones that have been made in the earliest life forms for over 750 million years. Phytoplankton, zooplankton, and most plants and animals that are exposed to sunlight have the capacity to make vitamin D. Vitamin D is critically important for the development, growth, and maintenance of ...

journal_title：Journal of cellular biochemistry

authors： Holick MF

更新日期：2003-02-01 00:00:00

abstract：:Vascularization is essential for bone development, fracture healing, and bone tissue engineering. We have previously described that coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves differentiation of both cell types. Investigating the role of microRNAs (miRNAs)...

journal_title：Journal of cellular biochemistry

authors： Strassburg S,Nabar N,Lampert F,Goerke SM,Pfeifer D,Finkenzeller G,Stark GB,Simunovic F

更新日期：2017-07-01 00:00:00

abstract：:L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) are adhesion molecules that play critical roles in neutrophil rolling during inflammation and lymphocyte homing. On the other hand they also function as signaling receptors to induce cytoskeleton changes. The present study is to investigate the signaling kinases...

journal_title：Journal of cellular biochemistry

authors： Luo J,Xu T,Wang X,Ba X,Feng X,Deepak V,Zeng X

更新日期：2010-07-01 00:00:00

abstract：:We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb Magnolia officinalis, induced apoptotic cell death in a dose- and time-dependent manner. A sustained inhibition of the major survival signal, Akt, occurred in magn...

journal_title：Journal of cellular biochemistry

authors： Lee DH,Szczepanski MJ,Lee YJ

更新日期：2009-04-15 00:00:00

abstract：:Activation of cytosolic phosphoinositide-3 kinase (PI-3K) signaling pathway has been well established to regulate gene expression, cell cycle, and survival by feeding signals to the nucleus. In addition, strong evidences accumulated over the past few years indicate the presence of an autonomous inositol lipid metaboli...

journal_title：Journal of cellular biochemistry

authors： Kikani CK,Dong LQ,Liu F

更新日期：2005-12-15 00:00:00