Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.

abstract：:O-linked N-acetylglucosamine (O-GlcNAc) glycosylation is a post-translational modification, which is believed antagonises phosphorylation. We have studied the O-GlcNAc level during Xenopus oocyte meiotic resumption, taking advantage of the high synchrony of this model which is dependent upon a burst of phosphorylation...

journal_title：Journal of cellular biochemistry

authors： Lefebvre T,Baert F,Bodart JF,Flament S,Michalski JC,Vilain JP

更新日期：2004-11-15 00:00:00

abstract：:To find the key factors that were involved in the survival and vascular endothelial differentiation of chick blatodisc induced by fibroblast growth factor 2 (FGF-2), we built a chick vasculogenesis model in vitro. Subsequently, the activities of phosphatidylcholine-specific phospholipase C (PC-PLC), including Ca(2+)-d...

journal_title：Journal of cellular biochemistry

authors： Zhao J,Zhao B,Wang W,Huang B,Zhang S,Miao J

更新日期：2007-10-01 00:00:00

abstract：:"microRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via downregulating PARP2," by Peng Teng, Yan Jiao, Min Hao, Xin Tang, J Cell Biochem. 2018; 5243-5252: The above article, published online on 13 December 2017 in Wiley Online Library (https://onlinelibrary.wiley.com/...

journal_title：Journal of cellular biochemistry

authors：

更新日期：2021-01-01 00:00:00

abstract：:Adenosine triphosphate (ATP), which plays a crucial role in both developing and mature cochleae, is released from greater epithelial ridge (GER) supporting cells of the rat cochlea, but the organelles in which ATP is stored have not yet been identified. Thus, we studied the organelles involved in ATP storage and sugge...

journal_title：Journal of cellular biochemistry

authors： Chen J,Hou S,Yang J

更新日期：2019-12-01 00:00:00

abstract：:Phospholipase C-gamma1 (PLCgamma1) plays a critical role in cell growth and proliferation by generating the second messengers, diacylglycerol and 1, 4, 5-inositol triphosphate. To investigate the roles of Src homology domain 2 and domain 3 of PLCgamma1 in PLCgamma1-mediated cell signaling, we characterized some protei...

journal_title：Journal of cellular biochemistry

authors： Bae JY,Ahn SJ,Lee JE,Kim JE,Han MR,Han W,Kim SW,Shin HJ,Lee SJ,Park D,Noh DY

更新日期：2005-04-01 00:00:00

abstract：:Transcription of the heat shock genes is regulated by the activation of the heat shock transcription factor (HSF-1). After heat shock, HSF-1 forms oligomers and binds to the heat shock element (HSE), which consists of several repeats of NGAAN located in the promoter region of the heat shock genes. HSF-1 is then phosph...

journal_title：Journal of cellular biochemistry

authors： Mivechi NF,Shi XY,Hahn GM

更新日期：1995-10-01 00:00:00

abstract：:Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer-related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its functions as an important role in various biological functions through the epigenetic regulation of gene transcription. However, the oncogenic effect...

journal_title：Journal of cellular biochemistry

authors： Sun W,Guo F,Liu M

更新日期：2018-04-01 00:00:00

abstract：:Thrombin increases the cytosolic Ca(2+) concentrations and induces NO production by activating proteinase-activated receptor 1 (PAR(1)) in vascular endothelial cells. The store-operated Ca(2+) influx is a major Ca(2+) influx pathway in non-excitable cells including endothelial cells and it has been reported to play a ...

journal_title：Journal of cellular biochemistry

authors： Hirano K,Hirano M,Hanada A

更新日期：2009-10-01 00:00:00

abstract：:All-trans retinoic acid and 9-cis-retinoic acid stimulate the activity of steroid sulfatase in HL60 acute myeloid leukemia cells in a concentration- and time-dependent manner. Neither of these 'natural retinoids' augmented steroid sulfatase activity in a HL60 sub-line that expresses a dominant-negative retinoic acid r...

journal_title：Journal of cellular biochemistry

authors： Hughes PJ,Zhao Y,Chandraratna RA,Brown G

更新日期：2006-02-01 00:00:00

abstract：:RECK is an anti-tumoral gene whose activity has been associated with its inhibitory effects regulating MMP-2, MMP-9, and MT1-MMP. RECK level decreases as gliobastoma progresses, varying from less invasive grade II gliomas to very invasive human glioblastoma multiforme (GBM). Since RECK expression and glioma invasivene...

journal_title：Journal of cellular biochemistry

authors： Silveira Corrêa TC,Massaro RR,Brohem CA,Taboga SR,Lamers ML,Santos MF,Maria-Engler SS

更新日期：2010-05-01 00:00:00

abstract：:Nuclear receptors (NRs) are key regulators of cell function and differentiation. We examined NR expression during osteogenic versus adipogenic differentiation of primary mouse calvarial osteoblasts (MOBs). MOBs were cultured for 21 days in osteogenic or adipogenic differentiation media. von Kossa and Oil Red O stainin...

journal_title：Journal of cellular biochemistry

authors： Pirih FQ,Abayahoudian R,Elashoff D,Parhami F,Nervina JM,Tetradis S

更新日期：2008-12-01 00:00:00

abstract：:Genomic imprinting is an epigenetic mechanism that restricts gene expression to one inherited allele. Improper maintenance of imprinting has been implicated in a number of human diseases and developmental syndromes. Assays are needed that can quantify the contribution of each paternal allele to a gene expression profi...

journal_title：Journal of cellular biochemistry

authors： Yang B,Damaschke N,Yao T,McCormick J,Wagner J,Jarrard D

更新日期：2015-07-01 00:00:00

abstract：:Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervo...

journal_title：Journal of cellular biochemistry

authors： Fukushima N

更新日期：2004-08-01 00:00:00

abstract：:Electrical activity in embryonic brain tissue has typically been studied using Micro Electrode Array (MEA) technology to make dozens of simultaneous recordings from dissociated neuronal cultures, brain stem cell progenitors, or brain slices from fetal rodents. Although these rodent neuronal primary culture electrical ...

journal_title：Journal of cellular biochemistry

authors： Napoli A,Obeid I

更新日期：2016-03-01 00:00:00

abstract：:The P-glycoprotein (p170, P-gp) encoded by human MDR1 gene functions as a pump to extrude anticancer drugs from cancer cells. Over-expression of p170 is closely related to primary and induced drug resistance phenotype of tumor cells. Recent studies have demonstrated that expression of cyclooxygenase-2 (COX-2) is posit...

journal_title：Journal of cellular biochemistry

authors： Xia W,Zhao T,Lv J,Xu S,Shi J,Wang S,Han X,Sun Y

更新日期：2009-09-01 00:00:00

abstract：:The study aims to investigate the analgesic effects of microRNA-129-5p (miR-129-5p) on bone cancer pain (BCP) by targeting Eph receptor B1 (EphB1) through the EphB1/EphrinB2 signaling pathway. BCP mice models were established, and C3H/HeJ female mice were classified into the normal, blank, negative control (NC), miR-1...

journal_title：Journal of cellular biochemistry

authors： Yu SN,Liu GF,Li LY,Zhao GQ,Liu L,Li XF

更新日期：2019-03-01 00:00:00

abstract：:We have previously demonstrated that the ultraviolet (UV) light is effective against a variety of cancer cells in vivo as well as in vitro. In the present report, we imaged the DNA damage repair response of minimal cancer after UVC irradiation. DNA-damage repair response to UV irradiation was imaged on tumors growing ...

journal_title：Journal of cellular biochemistry

authors： Miwa S,Yano S,Hiroshima Y,Tome Y,Uehara F,Mii S,Efimova EV,Kimura H,Hayashi K,Tsuchiya H,Hoffman RM

更新日期：2013-11-01 00:00:00

abstract：:By Western blot and immunostaining we proved that polyvinylpyrrolidone (PVP)-wrapped fullerene molecules (PVP-fullerene) could combine the 8- and 53-kb proteins which localize in the membrane of human skin keratinocytes HaCaT. Only fullerene molecules are able to cross the lipid membrane and conjugate 53-kb proteins i...

journal_title：Journal of cellular biochemistry

authors： Xiao L,Aoshima H,Saitoh Y,Miwa N

更新日期：2010-11-01 00:00:00

abstract：:Reveromycin A (RM-A), a small natural product isolated from Streptomyces bacteria, is a potential osteoporosis therapeutic in that it specifically induces apoptosis in osteoclasts but not osteoblasts. The purpose of the study presented here was to further elucidate the intracellular mechanisms of RM-A death effects in...

journal_title：Journal of cellular biochemistry

authors： Mead B,Morgan H,Mann-Knowlton A,Tedeschi L,Sloan C,Lang S,Hines C,Gragg M,Stofer J,Riemann K,Derr T,Heller E,Collins D,Landis P,Linna N,Jones D

更新日期：2015-08-01 00:00:00

abstract：:Our laboratory pioneered patient-derived orthotopic xenograft (PDOX) mouse models using surgical orthotopic implantation (SOI). PDOX models are patient-like, in contrast to the ectopic subcutaneous-transplant cancer models. In the present study, we demonstrate that an undifferentiated pleomorphic soft-tissue sarcoma (...

journal_title：Journal of cellular biochemistry

authors： Kiyuna T,Murakami T,Tome Y,Igarashi K,Kawaguchi K,Russell T,Eckardt MA,Crompton J,Singh A,Bernthal N,Bukata S,Federman N,Kanaya F,Eilber FC,Hoffman RM

更新日期：2017-02-01 00:00:00

abstract：:The human myeloid nuclear differentiation antigen (MNDA) is expressed specifically in maturing cells of the myelomonocytic lineage and in monocytes and granulocytes. Epitope enhancement was used to confirm the strict lineage- and stage-specific expression of MNDA in bone marrow as well as in other paraffin-embedded fi...

journal_title：Journal of cellular biochemistry

authors： Kao WY,Briggs JA,Kinney MC,Jensen RA,Briggs RC

更新日期：1997-05-01 00:00:00

abstract：:The spatial and temporal coordination of the many events required for osteogenic cells to create a mineralized matrix are only partially understood. The complexity of this process, and the nature of the final product, demand that these cells have mechanisms to carefully monitor events in the extracellular environment ...

journal_title：Journal of cellular biochemistry

authors： Beck GR Jr

更新日期：2003-10-01 00:00:00

abstract：:Peptidylarginine deiminase is localized in the cytosol of the luminal and glandular epithelia of the nonpregnant murine uterus and its expression is regulated by sex hormones [Takahara et al., [1989]: J Biol Chem 264, 13361-13368; Takahara et al. [1992]: J Biol Chem 267,520-525]. Here, we demonstrate that changes occu...

journal_title：Journal of cellular biochemistry

authors： Arai T,Kusubata M,Kohsaka T,Shiraiwa M,Sugawara K,Takahara H

更新日期：1995-07-01 00:00:00

abstract：:Intact human erythrocytes, initially depleted of Mg2+ by EDTA incubation in the presence of A23187, exhibit Mg(2+)-dependent phosphate production of around 1.5 mmol per liter cells.h, half-maximally activated at around 0.4 mM added free Mg2+. This appears to correspond to Mg(2+)-stimulated adenosine triphosphatase (Mg...

journal_title：Journal of cellular biochemistry

authors： Xu YH,Lu ZY,Conigrave AD,Auland ME,Roufogalis BD

更新日期：1991-08-01 00:00:00

abstract：:Regulation of cytoplasmic free calcium concentration [Ca(2+)]i is a key factor for the maintenance of cellular homeostasis in different cell types, including lymphocytes. During T lymphocyte activation as well as production of cytokines, sustained Ca(2+) influx is essential, however, it remains unclear how this influx...

journal_title：Journal of cellular biochemistry

authors： Tomilin VN,Cherezova AL,Negulyaev YA,Semenova SB

更新日期：2016-01-01 00:00:00

abstract：:Emerging evidence indicates that some altered patterns of methylation that occur in breast tumors may also be found in breast tissue of healthy women in relation to the breast cancer (BC) risk factors. Progesterone receptor (PR) isoform α is a crucial regulator of breast hormone responsiveness and its hypermethylation...

journal_title：Journal of cellular biochemistry

authors： Daraei A,Izadi P,Khorasani G,Nafissi N,Naghizadeh MM,Younosi N,Meysamie A,Mansoori Y,Nariman-Saleh-Fam Z,Bastami M,Saadatian Z,Zendehbad Z,Tavakkoly-Bazzaz J

更新日期：2019-08-01 00:00:00

abstract：:Dynamic interactions between cellular membranes and the cytoskeleton are known to play major roles in many cellular responses to environmental cues. External signals resulting in proliferation, differentiation, polarization, and motility must be translated from chemical signals into changes of state, often involving t...

journal_title：Journal of cellular biochemistry

authors： Qi M,Liu Y,Freeman MR,Solomon KR

更新日期：2009-04-15 00:00:00

abstract：:During cardiac muscle development, most cardiomyocytes permanently withdraw from the cell cycle. Previously, by suppressive subtractive hybridization, we identified calcyclin-binding protein/Siah-interacting protein (CacyBP/SIP) as one of the candidates being upregulated in the hyperplastic to hypertrophic switch, sug...

journal_title：Journal of cellular biochemistry

authors： Au KW,Kou CY,Woo AY,Chim SS,Fung KP,Cheng CH,Waye MM,Tsui SK

更新日期：2006-06-01 00:00:00

abstract：:We investigated the association of DNA polymerase and DNA primase activity with the nuclear matrix in HeLa S3 cells diluted with fresh medium after having been cultured without any medium change for 7 days. Flow cytometric analysis demonstrated that just before dilution about 85% of the cells were in the G1 phase of t...

journal_title：Journal of cellular biochemistry

authors： Martelli AM,Capitani S,Neri LM

更新日期：1998-10-01 00:00:00

abstract：:Emerging evidence suggests that long noncoding RNAs (lncRNAs) are involved in many biological processes, such as cell growth, differentiation, apoptosis, and autophagy. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), highly expressed in endothelial cells, is well conserved and implicated in endothelia...

journal_title：Journal of cellular biochemistry

authors： Li S,Pan X,Yang S,Ma A,Yin S,Dong Y,Pei H,Bi X,Li W

更新日期：2019-03-01 00:00:00