Cholesterol-regulated stress fiber formation.

abstract：:Mesenchymal stem cells (MSCs) have been used in therapies for bone tissue healing. The aim of this study was to investigate the effect of cell source and osteoblast differentiation on gene expression profiles of MSCs from bone marrow (BM-MSCs) or adipose tissue (AT-MSCs) to contribute for selecting a suitable cell pop...

journal_title：Journal of cellular biochemistry

authors： Fideles SOM,Ortiz AC,Assis AF,Duarte MJ,Oliveira FS,Passos GA,Beloti MM,Rosa AL

更新日期：2019-02-11 00:00:00

abstract：:The secretion pathway of Saccharomyces cerevisiae was challenged by constitutively overexpressing plasmid-encoded acid phosphatase, a secreted endogenous glycoprotein. A 2-microns-based multicopy plasmid carrying the coding sequence of acid phosphatase under the control of a truncated variant of the strong constitutiv...

journal_title：Journal of cellular biochemistry

authors： Kleene R,Janes M,Meyhack B,Pulfer K,Hinnen A

更新日期：1995-02-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF), characterized by irreversible scarring and progressive destruction of the lung tissue, is one of the most common types of idiopathic interstitial pneumonia worldwide. However, there are no reliable candidates for curative therapies. Hence, elucidation of the mechanisms of IPF genes...

journal_title：Journal of cellular biochemistry

authors： Wang H,Xie Q,Ou-Yang W,Zhang M

更新日期：2018-12-02 00:00:00

abstract：:TNF-a is an important cytokine mediator of inflammation which suggests that inhibition of TNF activity may provide potential for clinical application. Recent data indicated that treatment of both human and mouse cells with Kavain significantly modulates P. gingivalis- and LPS-induced TNF-α expression. In order to obta...

journal_title：Journal of cellular biochemistry

authors： Tang X,Alasiri M,Bamashmous A,Aljahdali B,Cao F,Dibart S,Salih E

更新日期：2018-07-01 00:00:00

abstract：:Chromatin immunoprecipitation (ChIP) is an important technique for studying protein-DNA interactions. Whole genome ChIP methods have enjoyed much success, but are limited in that they cannot uncover important long-range chromatin interactions. Chromosome conformation capture (3C) and related methods are capable of det...

journal_title：Journal of cellular biochemistry

authors： Fullwood MJ,Ruan Y

更新日期：2009-05-01 00:00:00

abstract：:The present study investigated the action of copaiba oil (Copaifera reticulata) on the systemic inflammation, oxidative status, and liver cell metabolism of rats with adjuvant-induced arthritis. The later is an experimental autoimmune pathology that shares many features with the human rheumatoid arthritis. Holtzman ra...

journal_title：Journal of cellular biochemistry

authors： Castro Ghizoni CV,Arssufi Ames AP,Lameira OA,Bersani Amado CA,Sá Nakanishi AB,Bracht L,Marçal Natali MR,Peralta RM,Bracht A,Comar JF

更新日期：2017-10-01 00:00:00

abstract：:Colorectal cancer remains a leading malignancy in humans. The importance of epigenetic modification in the development of this disease is now being recognized. The reversible and dynamic nature of epigenetic modifications provides a promising strategy in colorectal cancer chemoprevention and treatment. Luteolin (LUT),...

journal_title：Journal of cellular biochemistry

authors： Zuo Q,Wu R,Xiao X,Yang C,Yang Y,Wang C,Lin L,Kong AN

更新日期：2018-11-01 00:00:00

abstract：:Whitmania pigra is a unique, fluid-sucking ectoparasite and an anticoagulant medical leech. The codon usage bias (CUB) is the nonuniform usage of synonymous codons in which some codons are more preferred than others. Here, we performed a comprehensive analysis of CUB of genes in W. pigra, analyzing 140 780 transcripts...

journal_title：Journal of cellular biochemistry

authors： Khan MS,Guan DL,Ma LB,Xie JY,Xu SQ

更新日期：2019-06-01 00:00:00

abstract：:Phospholipase C-gamma1 (PLCgamma1) plays a critical role in cell growth and proliferation by generating the second messengers, diacylglycerol and 1, 4, 5-inositol triphosphate. To investigate the roles of Src homology domain 2 and domain 3 of PLCgamma1 in PLCgamma1-mediated cell signaling, we characterized some protei...

journal_title：Journal of cellular biochemistry

authors： Bae JY,Ahn SJ,Lee JE,Kim JE,Han MR,Han W,Kim SW,Shin HJ,Lee SJ,Park D,Noh DY

更新日期：2005-04-01 00:00:00

abstract：:Fgf10 has a prominent role in organogenesis. In the developing lung, Fgf10 is dynamically expressed in the distal mesenchyme from where it diffuses and activates its epithelial receptor, Fgfr2b, to trigger budding. Little is known about how Fgf10 expression is regulated. Here we have identified a mouse lung-specific m...

journal_title：Journal of cellular biochemistry

authors： Jean JC,Lü J,Joyce-Brady M,Cardoso WV

更新日期：2008-04-15 00:00:00

abstract：:Atherosclerosis and related cardiovascular diseases (CVD) represent one of the greatest threats to human health worldwide. The protection of vascular smooth muscle cells (VSMCs) from apoptosis in the plaque has become an important therapeutic target for atherosclerotic plaque stabilization. A significant association o...

journal_title：Journal of cellular biochemistry

authors： Ye Y,Fu F,Li X,Yang J,Liu H

更新日期：2016-01-01 00:00:00

abstract：:Patients with cervical cancer have abnormal cell proliferation and invasion after many years of latency. However, the precise mechanisms remain unclear. Mitogen- and stress-activated kinase 2 (MSK2) is a serine/threonine kinase which displays a phenotype that promotes tumor growth and metastasis in many different type...

journal_title：Journal of cellular biochemistry

authors： Wu Y,Li H,Wang H,Zhang F,Cao H,Xu S

更新日期：2019-02-12 00:00:00

abstract：:In the present paper we aimed to characterize epigenetic aspects and analyze TP53 transcription in the 21 T series, composed of breast cell lines: non-cancerous H16N2; Atypical Ductal Hyperplasia 21PT; Ductal Carcinoma in situ 21NT and Invasive Metastatic Carcinoma 21MT1. We detected a global genomic hypomethylation i...

journal_title：Journal of cellular biochemistry

authors： Santos GC Jr,da Silva AP,Feldman L,Ventura GM,Vassetzky Y,de Moura Gallo CV

更新日期：2015-04-01 00:00:00

abstract：:The high incidence of obesity-related pathologies, led to the study of the mechanisms involved in preadipose cell proliferation and differentiation. Here, we demonstrate that modulation of erbB2, plays a fundamental role during proliferation and adipogenic induction of preadipocytes. Using 3T3-L1 cells as model, we de...

journal_title：Journal of cellular biochemistry

authors： Pagano E,Coso O,Calvo JC

更新日期：2008-05-01 00:00:00

abstract：:The process of oncogenic transformation has been widely studied but is still poorly understood. We have focused on the mechanism of deregulation of the c-myc gene during transformation of a temperature-sensitive SV40-transformed mouse cell line. Run-on transcription assays showed that the two c-myc minor promoters, P1...

journal_title：Journal of cellular biochemistry

authors： Luo Y,Kurz J,MacAfee N,Krause MO

更新日期：1997-02-01 00:00:00

abstract：:Uroplakin II (UPII) gene expression is highly tissue and cell specific, with mRNA present in the suprabasal cell layers of the bladder and urethra. Previous reports described the mouse UPII (mUPII) promoter as primarily urothelium selective. However, ectopic expression of a transgene under the 3.6 kb mUPII promoter wa...

journal_title：Journal of cellular biochemistry

authors： Kwon DN,Choi YJ,Park JY,Cho SK,Kim MO,Lee HT,Kim JH

更新日期：2006-10-01 00:00:00

abstract：:SIX5 is a member of the human SIX family of transcription factors, many of which are involved in eye development. However, SIX5 transcripts are known to be present at very low levels in cells and no study has yet convincingly demonstrated detection of endogenous SIX5 protein by Western blotting or immunolocalisation. ...

journal_title：Journal of cellular biochemistry

authors： Pham YC,Man Nt,Holt I,Sewry CA,Pall G,Johnson K,Morris GE

更新日期：2005-08-01 00:00:00

abstract：:To ascertain whether p53 deficiency in vivo leads to the deregulation of DNA methylation machinery prior to tumor development, we investigated the expression profile of DNA methyltransferases in the thymus and the liver of p53(+/+), p53(+/-), and p53(-/-) mice at 7 weeks of age before tumor development. The expression...

journal_title：Journal of cellular biochemistry

authors： Park IY,Sohn BH,Choo JH,Joe CO,Seong JK,Lee YI,Chung JH

更新日期：2005-02-15 00:00:00

abstract：:Vitamin D is one of the oldest hormones that have been made in the earliest life forms for over 750 million years. Phytoplankton, zooplankton, and most plants and animals that are exposed to sunlight have the capacity to make vitamin D. Vitamin D is critically important for the development, growth, and maintenance of ...

journal_title：Journal of cellular biochemistry

authors： Holick MF

更新日期：2003-02-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is known as one of important autoimmune disorders which can lead to joint pain and damage throughout body. Given that internal (ie, genetic and epigenetic alterations) and external factors (ie, lifestyle changes, age, hormones, smoking, stress, and obesity) involved in RA pathogenesis. Increa...

journal_title：Journal of cellular biochemistry

authors： Zakeri Z,Salmaninejad A,Hosseini N,Shahbakhsh Y,Fadaee E,Shahrzad MK,Fadaei S

更新日期：2019-03-01 00:00:00

abstract：:The three ingredients for the successful tissue engineering of bone and cartilage are regulatory signals, cells, and extracellular matrix. Recent advances in cellular and molecular biology of the growth and differentiation factors have set the stage for a symbiosis of biotechnology and biomaterials. Recent advances pe...

journal_title：Journal of cellular biochemistry

authors： Reddi AH

更新日期：1994-10-01 00:00:00

abstract：:The retinoblastoma susceptibility gene product, p105Rb (RB), is generally believed to be an important regulator in the control of cell growth, differentiation, and apoptosis. Several cellular factors that form complexes with RB and exert their cellular regulatory functions have been identified, such as the newly ident...

journal_title：Journal of cellular biochemistry

authors： Cui Y,Mirkia K,Florence Fu YH,Zhu L,Yokoyama KK,Chiu R

更新日期：2002-01-01 00:00:00

abstract：:One of the most frequent chromosomal translocation found in patients with acute myeloid leukemia (AML) is the t(8;21). This translocation involves the RUNX1 and ETO genes. The breakpoints regions for t(8;21) are located at intron 5 and intron 1 of the RUNX1 and ETO gene respectively. To date, no homologous sequences h...

journal_title：Journal of cellular biochemistry

authors： Stuardo M,Nicovani S,Javed A,Gutierrez S

更新日期：2013-11-01 00:00:00

abstract：:Cell proliferation requires the coordinate synthesis and degradation of many proteins. In addition to the well-characterized involvement of the proteasome in the degradation of several cell cycle-regulated proteins, it has been established that cysteine proteinases are also involved in the control of cell proliferatio...

journal_title：Journal of cellular biochemistry

authors： Torres C,Li M,Walter R,Sierra F

更新日期：2000-09-18 00:00:00

abstract：:Endothelins (ETs) are vasoconstrictive peptides produced mainly by endothelial cells. The ET receptors are expressed in many types of cells including osteoblast-like cells. The purpose of this study was to examine the effects of endothelin on the expression of osteoblastic phenotype-related genes. We found that endoth...

journal_title：Journal of cellular biochemistry

authors： Shioide M,Noda M

更新日期：1993-10-01 00:00:00

abstract：:Cerebral ischemia/reperfusion (I/R) typically occurs after mechanical thrombectomy to treat ischemic stroke, generation of reactive oxygen species (ROS) after reperfusion may result in neuronal insult, ultimately leading to disability and death. Regulated in development and DNA damage responses 1 (REDD1) is a conserve...

journal_title：Journal of cellular biochemistry

authors： Sun J,Yue F

更新日期：2019-09-01 00:00:00

abstract：:The effect of regucalcin, which is a regulatory protein of Ca(2+) signaling, on Ca(2+)-ATPase activity in isolated rat renal cortex mitochondria was investigated. The presence of regucalcin (50, 100, and 250 nM) in the enzyme reaction mixture led to a significant increase in Ca(2+)-ATPase activity. Regucalcin signific...

journal_title：Journal of cellular biochemistry

authors： Xue JH,Takahashi H,Yamaguchi M

更新日期：2000-10-20 00:00:00

abstract：:Neuropathic pain (NP) is a substantial clinical problem causing great injury to people word-widely. Although gene expression analyses had been performed previously, the mechanisms underlying the etiology and development of NP are still poorly understood. To understand the function genes involved in the etiology and de...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Wang J,Ji LJ,Li L,Wei M,Zhen S,Wen CC

更新日期：2017-12-01 00:00:00

abstract：:This study investigates the effect of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling pathway in vascular calcification (VC) via inducing Autophagy in renal vascular smooth muscle cells (VSMCs). VSMCs were assigned into six experimental groups: the normal control, high pho...

journal_title：Journal of cellular biochemistry

authors： Yao L,Wang J,Tian BY,Xu TH,Sheng ZT

更新日期：2017-12-01 00:00:00