Biological evidence of the relationship between Helicobacter pylori and associated extragastric diseases.

abstract：:Extracts of serum-free conditioned medium from human rhabdomyosarcoma A673 cells contain high molecular weight (HMW) transforming growth factors (TGFs) that can be partially purified by Bio-Gel P-100 and carboxymethyl (CM)-cellulose chromatography (Todaro et al: Proc Natl Acad Sci USA 77:5258, 1980). Reverse-phase hig...

journal_title：Journal of cellular biochemistry

authors： Stromberg K,Hudgins WR,Fryling CM,Hazarika P,Dedman JR,Pardue RL,Hargreaves WR,Orth DN

更新日期：1986-01-01 00:00:00

abstract：:NELL-1 (Nel-like molecule-1) is a secreted osteogenic growth factor first identified in human craniosynostosis (CS) patients. NELL-1 protein has been observed to promote bone and cartilage differentiation and to suppress adipogenesis in both in vitro and in vivo models. Despite these findings, the cell surface recepto...

journal_title：Journal of cellular biochemistry

authors： Shen J,James AW,Chung J,Lee K,Zhang JB,Ho S,Lee KS,Kim TM,Niimi T,Kuroda S,Ting K,Soo C

更新日期：2012-12-01 00:00:00

abstract：:We have previously demonstrated that hydrogen peroxide (H(2)O(2)) treatment of murine 70Z/3 pre-B lymphocytes inhibits the immune response to lipopolysaccharide by attenuating signaling through c-Jun N-terminal kinase (JNK) activation. In the present study, we further examined the signaling intermediates responsible f...

journal_title：Journal of cellular biochemistry

authors： Lee M,Koh WS

更新日期：2003-02-15 00:00:00

abstract：:Cigarette smoking has been suggested as a risk factor for several periodontal diseases. It has also been found that smokers respond less favorably than non-smokers to periodontal therapy. Previous work in our lab has shown that nicotine inhibits human gingival cell migration. Since myofibroblasts play an important rol...

journal_title：Journal of cellular biochemistry

authors： Fang Y,Svoboda KK

更新日期：2005-08-15 00:00:00

abstract：:Na+/D-glucose symport is a secondary active glucose transport mechanism expressed only in kidney proximal tubule and in small intestine. A monoclonal antibody that recognized the Na+/glucose symporter of pig renal brush border membranes also recognized a 75-kD protein in apical membranes isolated from highly different...

journal_title：Journal of cellular biochemistry

authors： Wu JS,Lever JE

更新日期：1989-05-01 00:00:00

abstract：:We have shown previously that the promotion of myofiber survival by the basement membrane component merosin (laminin-2 [alpha2beta1gamma1]/laminin-4 [alpha2beta2gamma1]) is dependent on the activity of the tyrosine kinase Fyn, whereas myofiber anoikis induced by merosin deficiency is dependent on the stress-activated ...

journal_title：Journal of cellular biochemistry

authors： Laprise P,Vallée K,Demers MJ,Bouchard V,Poirier EM,Vézina A,Reed JC,Rivard N,Vachon PH

更新日期：2003-08-15 00:00:00

abstract：:The role of insulin-like growth factor-I (IGF-I) in regulating estrogen receptor-alpha (ER-alpha) gene expression and activity was investigated in the human breast cancer cell line MCF-7. Treatment of cells with 40 ng/ml IGF-I resulted in a 60% decrease in ER-alpha protein concentration by 3 h, and the amount of ER-al...

journal_title：Journal of cellular biochemistry

authors： Stoica A,Saceda M,Fakhro A,Joyner M,Martin MB

更新日期：2000-01-01 00:00:00

abstract：:The Zika virus is a rapidly spreading Aedes mosquito-borne sickness, which creates an unanticipated linkage birth deformity and neurological turmoil. This study represents the use of the combinatorial immunoinformatics approach to develop a multiepitope subunit vaccine using the structural and nonstructural proteins o...

journal_title：Journal of cellular biochemistry

authors： Kumar Pandey R,Ojha R,Mishra A,Kumar Prajapati V

更新日期：2018-09-01 00:00:00

abstract：:This study aimed to elucidate the precise mechanisms underlying the protective effects of phosphoseryl-tRNA kinase (PSTK) against cisplatin-induced podocyte injury. PSTK overexpression and knockdown vectors were generated and transfected into murine podocyte cells-5. PSTK levels were measured, and transcriptome sequen...

journal_title：Journal of cellular biochemistry

authors： Zheng D,Zhao Y,Liu L,Sun X,Xia Y,Sun L,Xie K

更新日期：2019-06-01 00:00:00

abstract：UNLABELLED:Chemotherapy treatment is the standard in triple negative breast cancers, a cancer subgroup which lacks a specific target. The mechanisms leading to the response, as well as any markers that allow the differentiation between responder and non-responder groups prior to treatment are unknown. In parallel, miRN...

journal_title：Journal of cellular biochemistry

authors： Tormo E,Pineda B,Serna E,Guijarro A,Ribas G,Fores J,Chirivella E,Climent J,Lluch A,Eroles P

更新日期：2015-09-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00

abstract：:In the last 20 years, more than 1,500 gene therapy clinical trials have been approved worldwide targeting a variety of indications, from inherited monogenic diseases to acquired conditions such as cancer, cardiovascular and infectious diseases. However, concerns about the safety and efficacy of gene therapy pharmaceut...

journal_title：Journal of cellular biochemistry

authors： Coutu DL,Yousefi AM,Galipeau J

更新日期：2009-10-15 00:00:00

abstract：:With a signal trap method, we previously identified stromal interaction molecule (STIM: originally named as SIM) as a protein, which has a signal peptide in 1996. However, recent works have accumulated evidences that STIM1 and STIM2 reside in endoplasmic reticulum (ER) and that both mainly sense ER Ca(2+) depletion, w...

journal_title：Journal of cellular biochemistry

authors： Saitoh N,Oritani K,Saito K,Yokota T,Ichii M,Sudo T,Fujita N,Nakajima K,Okada M,Kanakura Y

更新日期：2011-01-01 00:00:00

abstract：:Loss of sensitivity to the negative growth regulator transforming growth factor beta (TGF beta) is a feature of many different tumor types and is likely involved in tumor progression. In some cases this loss of sensitivity to TGF beta has been shown to be manifest in the absence of membrane-associated TGF beta recepto...

journal_title：Journal of cellular biochemistry

authors： Alexandrow MG,Moses HL

更新日期：1997-09-15 00:00:00

abstract：:The present study aimed to determine the roles of miRNA-543 in osteoporosis in rats induced by ovariectomy. The osteoporosis rat model was established by ovariectomy induction. MiRNA-543 expression in osteoblasts was measured by quantitative real-time polymerase chain reaction. The cell proliferation and apoptosis wer...

journal_title：Journal of cellular biochemistry

authors： Li X,Ning L,Zhao X,Wan S

更新日期：2018-12-02 00:00:00

abstract：:Giant cell tumor of bone is a progressive, potentially malignant process which destroys skeletal tissue by virtue of its osteoclast complement. As a biological entity it provides a unique natural model of bone resorption by osteoclasts whose recruitment and development is controlled by a neoplastic population of fibro...

journal_title：Journal of cellular biochemistry

authors： Robinson D,Einhorn TA

更新日期：1994-07-01 00:00:00

abstract：:A better understanding of breast cancer pathogenesis would contribute to improved diagnosis and therapy and potentially decreased mortality rates. Here, we found that the MORC family CW-type zinc finger 4 (MORC4) overexpression in breast cancer tissues is associated with poor survival, and the short-interfering RNA kn...

journal_title：Journal of cellular biochemistry

authors： Yang Z,Zhuang Q,Hu G,Geng S

更新日期：2019-03-01 00:00:00

abstract：:Survivin is a member of the inhibitor of apoptosis (IAP) gene family, containing a single baculovirus IAP repeat (BIR) and no RING finger, that is expressed in many human cancers. Although it has been proposed to be involved in mitotic and cytokinetic processes, its functional subcellular distribution in the cytoplasm...

journal_title：Journal of cellular biochemistry

authors： Jiang X,Wilford C,Duensing S,Munger K,Jones G,Jones D

更新日期：2001-08-01 00:00:00

abstract：:In the process of isolated single liver cells coming together to form three-dimensional spheroids, cells undergo dramatic environmental changes. How liver cells respond to these changes has not been well studied before. This study characterized the functional and biochemical changes during liver spheroid formation and...

journal_title：Journal of cellular biochemistry

authors： Ma M,Xu J,Purcell WM

更新日期：2003-12-15 00:00:00

abstract：:Flavonoids are a group of naturally-occurring phenolic compounds in the plant kingdom, and many flavonoids are found with vascular protective properties. Nevertheless how the protective response is exerted by flavonoids is not well characterized. In view of the nuclear factor-kappaB (NFkappaB) may play a central role ...

journal_title：Journal of cellular biochemistry

authors： Tsai SH,Liang YC,Lin-Shiau SY,Lin JK

更新日期：1999-09-15 00:00:00

abstract：:Fluorescent proteins have enabled the color-coding of cells growing in vivo. Noninvasive imaging of cells expressing fluorescent proteins has allowed the real-time determination of the behavior of cancer cells, the progression of infection, the differentiation of stem cells, and interaction of stromal and cancer cells...

journal_title：Journal of cellular biochemistry

authors： Hoffman RM

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:Pancreatic adenocarcinoma (PAAD) is one of the most fatal cancers in the world for early metastasis, extensive invasion, and poor prognosis with a 5-year survival rate less than 5%. However, the underlying mechanisms are poorly understood. Therefore, it is urgent to explore molecular markers for early diag...

journal_title：Journal of cellular biochemistry

authors： Yang Y,Wang Y,Liu S,Zhao X,Jia R,Xiao Y,Zhang M,Li X,Li J,Wang W

更新日期：2018-11-28 00:00:00

abstract：:The function of the c-myc proto-oncogene in cell cycle progression remains unclear. In order to examine the role c-myc may play in cell cycle progression, we have expressed the hormone-inducible MycER protein in the nontransformed, EGF-dependent mouse keratinocyte cell line BALB/MK. We have found that activation of My...

journal_title：Journal of cellular biochemistry

authors： Alexandrow MG,Moses HL

更新日期：1998-09-15 00:00:00

abstract：:Relatively little is known about the spatial organization of RNA synthesis, processing, and transport in (mammalian) cell nuclei. This review summarizes results of electron microscopic mapping of RNA synthetic sites and macromolecules involved directly, or indirectly, in the metabolism of RNAs in somatic cell mammalia...

journal_title：Journal of cellular biochemistry

authors： Raska I

更新日期：1995-09-01 00:00:00

abstract：:X-ray atomic structure of recombinant Hell's gate globin I (HGbI) from Methylacidophilum infernorum was calculated from the X-ray diffraction data of two different types of crystals: obtained by classical hanging drop and by LB nanotemplate method under the same crystallization conditions. After the accurate compariso...

journal_title：Journal of cellular biochemistry

authors： Pechkova E,Scudieri D,Belmonte L,Nicolini C

更新日期：2012-07-01 00:00:00

abstract：:Tumor necrosis factor a (TNFa) is an inflammatory cytokine that plays a crucial role in the immune response and the progression of cervical lesions. There is a growing body of data evaluating the value of a genetic variant in the TNFa gene with the risk of developing cervical cancer. The aim of this study was to explo...

journal_title：Journal of cellular biochemistry

authors： Babapour N,Mehramiz M,Rastgar Moghadam A,Behboodi N,Yousefi Z,Maftouh M,Talebian S,Khazaei M,Jafarian A,Sharifi-Sistani N,Avan A,Hasanzadeh M

更新日期：2019-04-01 00:00:00

abstract：:Successful implantation and placentation requires that extravillous cytotrophoblast acquires an endovascular phenotype and remodels uterine spiral arteries. Defects in this mechanism correlate with severe obstetric complications as implantation failure and preeclampsia. Lysophosphatidic acid (LPA) participates in embr...

journal_title：Journal of cellular biochemistry

authors： Beltrame JS,Sordelli MS,Cañumil VA,Franchi AM,Ribeiro ML

更新日期：2018-01-01 00:00:00

abstract：:The effect of regucalcin, which is a regulatory protein of Ca(2+) signaling, on Ca(2+)-ATPase activity in isolated rat renal cortex mitochondria was investigated. The presence of regucalcin (50, 100, and 250 nM) in the enzyme reaction mixture led to a significant increase in Ca(2+)-ATPase activity. Regucalcin signific...

journal_title：Journal of cellular biochemistry

authors： Xue JH,Takahashi H,Yamaguchi M

更新日期：2000-10-20 00:00:00

abstract：:Resveratrol, a polyphenol found in fruits, has been demonstrated to activate Sir2. Though many studies have demonstrated that resveratrol can activate SIRT1, whether it has effect on other sirtuins (SIRT2-7) are unknown. The present study shows that exposure of H9c2 cells to 50 microM H(2)O(2) for 6 h caused a signifi...

journal_title：Journal of cellular biochemistry

authors： Yu W,Fu YC,Zhou XH,Chen CJ,Wang X,Lin RB,Wang W

更新日期：2009-07-01 00:00:00

abstract：:Conservative treatment for invasive bladder cancer (BC) involves a complete transurethral tumor resection combined with chemotherapy (CT) and radiotherapy (RT). The major obstacles of chemo-radiotherapy are the addition of the toxicities of RT and CT, and the recurrence due to RT and CT resistances. The flavonoid Sily...

journal_title：Journal of cellular biochemistry

authors： Prack Mc Cormick B,Langle Y,Belgorosky D,Vanzulli S,Balarino N,Sandes E,Eiján AM

更新日期：2018-07-01 00:00:00