A continuum of T 2 * components: Flexible fast fraction mapping in sodium MRI.

Abstract:

PURPOSE:Parameter mapping in sodium MRI data is challenging due to inherently low SNR and spatial resolution, prompting the need to employ robust models and estimation techniques. This work aims to develop a continuum model of sodium T 2 * -decay to overcome the limitations of the commonly employed bi-exponential models. Estimates of mean T 2 * -decay and fast component fraction in tissue are emergent from the inferred continuum model. METHODS:A closed-form continuum model was derived assuming a gamma distribution of T 2 * components. Sodium MRI was performed on four healthy human subjects and a phantom consisting of closely packed vials filled with an aqueous solution of varying sodium and agarose concentrations. The continuum model was applied to the phantom and in vivo human multi-echo 7T data. Parameter maps by voxelwise model-fitting were obtained. RESULTS:The continuum model demonstrated comparable estimation performance to the bi-exponential model. The parameter maps provided improved contrast between tissue structures. The fast component fraction, an indicator of the heterogeneity of localised sodium motion regimes in tissue, was zero in CSF and high in WM structures. CONCLUSIONS:The continuum distribution model provides high quality, high contrast parameter maps, and informative voxelwise estimates of the relative weighting between fast and slow decay components.

journal_name

Magn Reson Med

authors

Syeda W,Blunck Y,Kolbe S,Cleary JO,Johnston LA

doi

10.1002/mrm.27659

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

3854-3864

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

81

pub_type

杂志文章
  • Three-dimensional whole body imaging of spin probes in mice by time-domain radiofrequency electron paramagnetic resonance.

    abstract::Imaging of stable paramagnetic spin probes in phantom objects and in vivo was evaluated using a RF time domain EPR spectrometer/imager operating at 300 MHz. Projections were collected using static magnetic field gradients and images were reconstructed using filtered back-projection techniques. Results from phantom obj...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(200003)43:3<375::aid-mrm9>

    authors: Afeworki M,van Dam GM,Devasahayam N,Murugesan R,Cook J,Coffin D,Larsen JH,Mitchell JB,Subramanian S,Krishna MC

    更新日期:2000-03-01 00:00:00

  • Improved MUSSELS reconstruction for high-resolution multi-shot diffusion weighted imaging.

    abstract:PURPOSE:MUSSELS is a one-step iterative reconstruction method for multishot diffusion weighted (msDW) imaging. The current work presents an efficient implementation, termed IRLS MUSSELS, that enables faster reconstruction to enhance its utility for high-resolution diffusion MRI studies. METHODS:The recently proposed M...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28090

    authors: Mani M,Aggarwal HK,Magnotta V,Jacob M

    更新日期:2020-06-01 00:00:00

  • Evidence that both fast and slow water ADC components arise from intracellular space.

    abstract::Evaluation of water diffusion in the brain has revealed both fast- and slow-diffusing water populations. It has been suggested that these populations represent extra- and intracellular water, respectively. We have identified and characterized both populations in the intracellular space of the Xenopus oocyte. We have a...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10301

    authors: Sehy JV,Ackerman JJ,Neil JJ

    更新日期:2002-11-01 00:00:00

  • Fast model-based T2 mapping using SAR-reduced simultaneous multislice excitation.

    abstract:PURPOSE:To obtain whole-brain high-resolution T2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. METHODS:A multi-echo spin-echo sequence was modified to acquire multiple s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27890

    authors: Hilbert T,Schulz J,Marques JP,Thiran JP,Krueger G,Norris DG,Kober T

    更新日期:2019-12-01 00:00:00

  • Correction for geometric distortion in echo planar images from B0 field variations.

    abstract::A method is described for the correction of geometric distortions occurring in echo planar images. The geometric distortions are caused in large part by static magnetic field inhomogeneities, leading to pixel shifts, particularly in the phase encode direction. By characterizing the field inhomogeneities from a field m...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910340111

    authors: Jezzard P,Balaban RS

    更新日期:1995-07-01 00:00:00

  • T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo.

    abstract::T2-weighted MRI of edema in acute myocardial infarction (MI) provides a means of differentiating acute and chronic MI, and assessing the area at risk of infarction. Conventional T2-weighted imaging of edema uses a turbo spin-echo (TSE) readout with dark-blood preparation. Clinical applications of dark-blood TSE method...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21215

    authors: Kellman P,Aletras AH,Mancini C,McVeigh ER,Arai AE

    更新日期:2007-05-01 00:00:00

  • In vivo detection of 2-hydroxyglutarate in brain tumors by optimized point-resolved spectroscopy (PRESS) at 7T.

    abstract:PURPOSE:To test the efficacy of 7T MRS for in vivo detection of 2-hydroxyglutarate (2HG) in brain tumors. METHODS:The subecho times of point-resolved spectroscopy (PRESS) were optimized at 7T with density-matrix simulations and phantom validation to improve the 2HG signal selectivity with respect to the neighboring re...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26190

    authors: Ganji SK,An Z,Tiwari V,McNeil S,Pinho MC,Pan E,Mickey BE,Maher EA,Choi C

    更新日期:2017-03-01 00:00:00

  • Machine learning RF shimming: Prediction by iteratively projected ridge regression.

    abstract:PURPOSE:To obviate online slice-by-slice RF shim optimization and reduce B1+ mapping requirements for patient-specific RF shimming in high-field magnetic resonance imaging. THEORY AND METHODS:RF Shim Prediction by Iteratively Projected Ridge Regression (PIPRR) predicts patient-specific, SAR-efficient RF shims with a m...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27192

    authors: Ianni JD,Cao Z,Grissom WA

    更新日期:2018-11-01 00:00:00

  • Noninvasive in vivo oximetric imaging by radiofrequency FT EPR.

    abstract::A novel method, called relaxo-oximetry, for rapid spatially resolved in vivo measurements of oxygen concentration using time-domain radiofrequency (RF) electron paramagnetic resonance (EPR) is described. Time-domain data from triaryl methyl (TAM)-based single-electron contrast agents were processed by systematic delet...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10133

    authors: Subramanian S,Yamada K,Irie A,Murugesan R,Cook JA,Devasahayam N,Van Dam GM,Mitchell JB,Krishna MC

    更新日期:2002-05-01 00:00:00

  • Unaliasing by fourier-encoding the overlaps using the temporal dimension (UNFOLD), applied to cardiac imaging and fMRI.

    abstract::In several applications, MRI is used to monitor the time behavior of the signal in an organ of interest; e.g., signal evolution because of physiological motion, activation, or contrast-agent accumulation. Dynamic applications involve acquiring data in a k-t space, which contains both temporal and spatial information. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199911)42:5<813::aid-mrm1>

    authors: Madore B,Glover GH,Pelc NJ

    更新日期:1999-11-01 00:00:00

  • Commissioning of MRI-only based treatment planning procedure for external beam radiotherapy of prostate.

    abstract::In radiotherapy, target tissues are defined best on MR images due to their superior soft tissue contrast. Computed tomography imaging is geometrically accurate and it is needed for dose calculation and generation of reference images for treatment localization. Co-registration errors between MR and computed tomography ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/mrm.24459

    authors: Kapanen M,Collan J,Beule A,Seppälä T,Saarilahti K,Tenhunen M

    更新日期:2013-07-01 00:00:00

  • Assessing linear time-invariance in human primary somatosensory cortex with BOLD fMRI using vibrotactile stimuli.

    abstract::The assumption of linear time-invariance (LTI) in the human primary somatosensory cortex (SI) is assessed for fMRI signals generated by variable-duration vibrotactile stimuli. Predictions based on time-shifted summation (TSS) of responses to 2 s stimuli overestimate observed BOLD signal amplitudes in response to longe...

    journal_title:Magnetic resonance in medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/mrm.20363

    authors: Nangini C,Macintosh BJ,Tam F,Staines WR,Graham SJ

    更新日期:2005-02-01 00:00:00

  • Measurement of myocardial frequency offsets during first pass of a gadolinium-based contrast agent in perfusion studies.

    abstract::MRI of myocardial perfusion observed with an extracellular contrast agent has proven valuable for the detection of coronary artery disease. During contrast enhancement transient dark rim artifacts are sometimes visible, complicating diagnosis and quantification. In this work a quantification of the frequency offsets c...

    journal_title:Magnetic resonance in medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/mrm.21723

    authors: Ferreira P,Gatehouse P,Bucciarelli-Ducci C,Wage R,Firmin D

    更新日期:2008-10-01 00:00:00

  • High-frequency subband compressed sensing MRI using quadruplet sampling.

    abstract:PURPOSE:To present and validate a new method that formalizes a direct link between k-space and wavelet domains to apply separate undersampling and reconstruction for high- and low-spatial-frequency k-space data. THEORY AND METHODS:High- and low-spatial-frequency regions are defined in k-space based on the separation o...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24592

    authors: Sung K,Hargreaves BA

    更新日期:2013-11-01 00:00:00

  • Iterative projection onto convex sets for quantitative susceptibility mapping.

    abstract:PURPOSE:Quantitative susceptibility map (QSM) reconstruction is ill posed due to the zero values on the "magic angle cone" that make the maps prone to streaking artifacts. We propose projection onto convex sets (POCS) in the method of steepest descent (SD) for QSM reconstruction. METHODS:Two convex projections, an obj...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25155

    authors: Deng W,Boada F,Poser BA,Schirda C,Stenger VA

    更新日期:2015-02-01 00:00:00

  • Application of image registration to measurement of intervertebral rotation in the lumbar spine.

    abstract::In this study, the precision and accuracy of a new method for measuring axial rotations of the lumbar vertebrae, which are thought to be increased in patients with degenerative spinal instability, were estimated. A standard image registration algorithm involving a user-selected center of rotation was adapted for this ...

    journal_title:Magnetic resonance in medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/mrm.10319

    authors: Rogers BP,Haughton VM,Arfanakis K,Meyerand ME

    更新日期:2002-12-01 00:00:00

  • Increased robustness in reference region model analysis of DCE MRI using two-step constrained approaches.

    abstract:PURPOSE:Reference region models (RRMs) can quantify tumor perfusion in dynamic contrast-enhanced MRI without an arterial input function. Inspection of the RRM reveals that one of the free parameters in the fit is uniquely linked to the reference region and is common to all voxels. A two-step approach is proposed that t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26530

    authors: Ahmed Z,Levesque IR

    更新日期:2017-10-01 00:00:00

  • RAPID--a new method for fast imaging using a single slice of Z-magnetization.

    abstract::A single slice of z-magnetization is used to generate high-speed images. The slice selection step is achieved using two sin-sinc pulses. This procedure eliminates the need for continual slice gradient reversal, a requirement for the FLASH technique. The RAPID imaging method has less inherent T1 and/or T2 dependence th...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910050213

    authors: Brooks WM,Brereton IM,Doddrell DM

    更新日期:1987-08-01 00:00:00

  • Three-dimensional water/fat separation and T2* estimation based on whole-image optimization--application in breathhold liver imaging at 1.5 T.

    abstract::The chemical shift of water and fat resonances in proton MRI allows separation of water and fat signal from chemical shift encoded data. This work describes an automatic method that produces separate water and fat images as well as quantitative maps of fat signal fraction and T2* from complex multiecho gradient-recall...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23185

    authors: Berglund J,Kullberg J

    更新日期:2012-06-01 00:00:00

  • Indirect 17(O)-magnetic resonance imaging of cerebral blood flow in the rat.

    abstract::Proton T(1rho)-dispersion MRI is demonstrated for indirect, in vivo detection of (17)O in the brain. This technique, which may be readily implemented on any clinical MRI scanner, is applied towards high-resolution, quantitative mapping of cerebral blood flow (CBF) in the rat by monitoring the clearance of (17)O-enrich...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10403

    authors: Tailor DR,Roy A,Regatte RR,Charagundla SR,McLaughlin AC,Leigh JS,Reddy R

    更新日期:2003-03-01 00:00:00

  • Synchronous MRI of muscle motion induced by electrical stimulation.

    abstract:PURPOSE:Assessing the functionality of muscle fibers is essential to monitor both pathological and physiological processes. Here, we present a new method for accurate, quantitative measurement of muscle contraction with magnetic resonance imaging (MRI) using an electrical muscle stimulator (EMS), hence allowing the dir...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26154

    authors: Deligianni X,Pansini M,Garcia M,Hirschmann A,Schmidt-Trucksäss A,Bieri O,Santini F

    更新日期:2017-02-01 00:00:00

  • Partial-volume effect on ischemic tissue-fate delineation using quantitative perfusion and diffusion imaging on a rat stroke model.

    abstract::Partial-volume effects (PVE) in stroke imaging could hinder proper delineation of normal, ischemic, and at-risk tissues. Cerebral-blood-flow (CBF) and apparent diffusion coefficient (ADC) were measured at high and low resolution (HR = 128 x 128, LR = 64 x 64) in focal ischemia in rats during the acute phase. The data ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20299

    authors: Ren H,Shen Q,Bardutzky J,Fisher M,Duong TQ

    更新日期:2004-12-01 00:00:00

  • A fast, analytically based method to optimize local transmit efficiency for a transmit array.

    abstract:PURPOSE:To develop an analytically based algorithm for rapid optimization of the local radiofrequency magnetic (B1+) field intensity for a given radiofrequency power through a transmit array. The analytical nature of the method will yield insight to optimization requirements and provides a valuable reference for numeri...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24653

    authors: Carluccio G,Collins CM,Erricolo D

    更新日期:2014-01-01 00:00:00

  • Analysis of the evolution of focal cerebral ischemia in the rat using the eigenimage filter.

    abstract::The eigenimage filter was used to evaluate the results of a MRI study of cerebral ischemia in a rat model. This linear filter segments a desired feature in an image sequence from other features which may interfere with its observation. The animals were imaged temporally, after occlusion of the middle cerebral artery, ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910260207

    authors: Peck DJ,Spickler EM,Knight RA,Hearshen DO,Windham JP

    更新日期:1992-08-01 00:00:00

  • Iterative reweighted linear least squares for accurate, fast, and robust estimation of diffusion magnetic resonance parameters.

    abstract:PURPOSE:Diffusion-weighted magnetic resonance imaging suffers from physiological noise, such as artifacts caused by motion or system instabilities. Therefore, there is a need for robust diffusion parameter estimation techniques. In the past, several techniques have been proposed, including RESTORE and iRESTORE (Chang e...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25351

    authors: Collier Q,Veraart J,Jeurissen B,den Dekker AJ,Sijbers J

    更新日期:2015-06-01 00:00:00

  • 31P RINEPT MRSI and VBM reveal alterations in brain aging associated with major depression.

    abstract:PURPOSE:Phosphomono- and diesters, the major components of the choline peak in (1) H magnetic resonance spectroscopy, are associated with membrane anabolic and catabolic mechanisms. With the refocused insensitive nuclei-enhanced polarization transfer technique, these phospholipids are edited and enhanced in the (31) P ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25278

    authors: Biedermann SV,Weber-Fahr W,Demirakca T,Tunc-Skarka N,Hoerst M,Henn F,Sartorius A,Ende G

    更新日期:2015-04-01 00:00:00

  • 1H NMR relaxation measurements of human tissues in situ by spatially resolved spectroscopy.

    abstract::Spatially resolved spectroscopy (SPARS) is a method for obtaining high-resolution NMR spectra of well-defined volumes of human tissues in situ. This method was combined with the Carr-Purcell-Meiboom-Gill multiple-echo sequence for T2, and with inversion recovery for T1 relaxation measurements. Relaxation times obtaine...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910040504

    authors: Luyten PR,Anderson CM,den Hollander JA

    更新日期:1987-05-01 00:00:00

  • 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer.

    abstract::High polarization of nuclear spins in liquid state through hyperpolarized technology utilizing dynamic nuclear polarization has enabled the direct monitoring of (13)C metabolites in vivo at a high signal-to-noise ratio. Acquisition time limitations due to T(1) decay of the hyperpolarized signal require accelerated ima...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22233

    authors: Hu S,Lustig M,Balakrishnan A,Larson PE,Bok R,Kurhanewicz J,Nelson SJ,Goga A,Pauly JM,Vigneron DB

    更新日期:2010-02-01 00:00:00

  • Prospective multiaxial motion correction for fMRI.

    abstract::Corruption of the image time series due to interimage head motion limits the clinical utility of functional MRI. This paper presents a method for real-time prospective correction of rotation and translation in all six degrees of rigid body motion. By incorporating an orbital navigator (ONAV) echo for each of the sagit...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(200003)43:3<459::aid-mrm19

    authors: Ward HA,Riederer SJ,Grimm RC,Ehman RL,Felmlee JP,Jack CR Jr

    更新日期:2000-03-01 00:00:00

  • Improved myo-inositol detection through Carr-Purcell PRESS: a tool for more sensitive mild cognitive impairment diagnosis.

    abstract::A 3-T study is presented, comparing the ability of two (1) H spectroscopy pulse sequences, Carr-Purcell point resolved spectroscopy (CPRESS; TE = 45 msec), and conventional PRESS (TE = 35 msec), to separate between groups of 20 normal control (NC) and 20 mild cognitive impairment (MCI) subjects. Both sequences showed ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22749

    authors: Hancu I,Gillen R,Cowan J,Zimmerman EA

    更新日期:2011-06-01 00:00:00