Abstract:
:Spatially resolved spectroscopy (SPARS) is a method for obtaining high-resolution NMR spectra of well-defined volumes of human tissues in situ. This method was combined with the Carr-Purcell-Meiboom-Gill multiple-echo sequence for T2, and with inversion recovery for T1 relaxation measurements. Relaxation times obtained by SPARS were compared with standard CPMG and IR relaxation measurements and with imaging methods, using a number of relaxation phantoms. Spectroscopically resolved relaxation data of human bone marrow, muscle, and adipose tissue in situ were obtained. T2 measurements of human adipose tissue gave different results when using single-echo measurements rather than the CPMG method. This difference was interpreted as a J modulation effect, which shows up in fatty acid proton resonances. This J modulation effect influences the intensity of adipose tissue in routine 1H NMR images.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Luyten PR,Anderson CM,den Hollander JAdoi
10.1002/mrm.1910040504subject
Has Abstractpub_date
1987-05-01 00:00:00pages
431-40issue
5eissn
0740-3194issn
1522-2594journal_volume
4pub_type
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