Ongoing and future directions in the management of metastatic colorectal cancer: Update on clinical trials.

abstract：BACKGROUND AND OBJECTIVES:Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa. Macrophage migration inhibitory factor (MIF) plays an important role in the pro- and anti-inflammatory response to infection. This study is aimed at investigating th...

journal_title：Journal of surgical oncology

authors： Ding GX,Zhou SQ,Xu Z,Feng NH,Song NH,Wang XJ,Yang J,Zhang W,Wu HF,Hua LX

更新日期：2009-08-01 00:00:00

abstract：:Malignant transformation in cells is accompanied by enzymatic changes that may be useful markers of malignancy. Studies of oncofetal antigens in gastric juice show an increased concentration in patients with gastric carcinoma. The object of the present study was to test if the concentration of lysosomal enzymes and ca...

journal_title：Journal of surgical oncology

authors： Graffner H,Hultberg B

更新日期：1983-11-01 00:00:00

abstract：:Metastatic liver disease is the commonest cause of death in patients with colorectal cancer. A small proportion of these patients (10%) may be treated by surgical resection with five year survival approaching 35-40%. Alternative treatment modalities for localised hepatic disease include in situ ablative techniques tha...

journal_title：Journal of surgical oncology

authors： Muralidharan V,Christophi C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pheochromocytoma (PHEO) and paraganglioma (PGL) are rare tumors. Aims of this study were to describe and to compare demographic, clinical, pathologic, and survival characteristics of malignant PHEO and PGL. METHODS:Patients were identified in SEER, 1988-2009. Analyses included chi-square, ANO...

journal_title：Journal of surgical oncology

authors： Goffredo P,Sosa JA,Roman SA

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Open surgery for hilar cholangiocarcinoma (HCCA) has already been widely reported and analyzed. However, the laparoscopic technique for treating HCCA remains controversial because of the lack of radicality and poor assessment of the resectability of hilar structures without direct palpation. The aim of this ...

journal_title：Journal of surgical oncology

authors： Feng F,Cao X,Liu X,Qin J,Zhang S,Li Q,Liu J

更新日期：2019-12-01 00:00:00

abstract：:This paper reports on two patients, who both were under treatment for osteosarcoma of the femur. Treatment consisted of chemotherapy, resection of the tumour, and reconstruction with an endoprosthesis . Both patients sustained an epiphyseal fracture on two occasions after a minor trauma. Careful observations of the x-...

journal_title：Journal of surgical oncology

authors： Veth RP,De Graaf SS,Den Heeten GJ,Oldhoff J,Hoekstra HJ,Schraffordt Koops H,Nielsen HK

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate the efficacy of preoperative ultrasound (US) scanning in identifying lymph node metastasis before sentinel node biopsy (SNB), we conducted a prospective study on 125 patients with primary cutaneous melanoma (CM). METHODS:We prospectively enrolled 125 patients with >1 mm thick CM a...

journal_title：Journal of surgical oncology

authors： Rossi CR,Mocellin S,Scagnet B,Foletto M,Vecchiato A,Pilati P,Tregnaghi A,Zavagno G,Stramare R,Rubaltelli L,Montesco C,Borsato S,Rubello D,Lise M

更新日期：2003-06-01 00:00:00

abstract：:The clinical evidence suggests that the steroid hormones may influence the biologic course of tumors of soft tissue. In an attempt to characterize the possible steroid hormone dependency of soft tissue, we studied the incidence and distribution of cytosolic receptors for the steroid hormones in benign and malignant tu...

journal_title：Journal of surgical oncology

authors： Chaudhuri PK,Walker MJ,Beattie CW,Das Gupta TK

更新日期：1985-02-01 00:00:00

abstract：:DNA nuclear content and PCNA index (proportion of PCNA reactive cells) have been studied by flow cytometry in eight pancreatic lesions producing hyperinsulinemic hypoglycemia to assess DNA ploidy and tumoral growth fraction. Adult nesidioblastosis had a diploid DNA index, two adenomas were near diploid, and four of th...

journal_title：Journal of surgical oncology

authors： Losada J,Sarria R,Fernandez Val JF,Lopez Ariztegui MA

更新日期：1995-05-01 00:00:00

abstract：:The records of 130 patients with soft tissue and bone sarcomas were retrospectively analyzed to identify the subgroups of patients that would benefit from tomographic studies for pulmonary metastasis. Sixty-six of 96 patients with a normal conventional chest roentgenogram (CXR) had tomography to diagnose pulmonary met...

journal_title：Journal of surgical oncology

authors： Duda RB,Beatty JD,Kokal WA,Riihimaki DU,Terz JJ

更新日期：1988-08-01 00:00:00

abstract：INTRODUCTION:The ACS-NSQIP surgical risk calculator is an open-access on-line tool that estimates the risk of adverse post-operative outcomes for a wide range of surgical procedures. Wide surgical resection of soft tissue sarcoma (STS) often requires complex reconstructive procedures that can be associated with relativ...

journal_title：Journal of surgical oncology

authors： Slump J,Ferguson PC,Wunder JS,Griffin A,Hoekstra HJ,Bagher S,Zhong T,Hofer SO,O'Neill AC

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC. PATIENTS AND METHODS:We det...

journal_title：Journal of surgical oncology

authors： Vashist YK,Uzungolu G,Kutup A,Gebauer F,Koenig A,Deutsch L,Zehler O,Busch P,Kalinin V,Izbicki JR,Yekebas EF

更新日期：2011-09-01 00:00:00

abstract：:A case of desmoid tumor of 17 years' duration associated with cystosarcoma phyllodes of 17 months' duration is presented. Good initial response to radiation therapy of the desmoid tumor was shown. Poor response of cytosarcoma phyllodes to radiation therapy was noted. A comparison between the similarities and differenc...

journal_title：Journal of surgical oncology

authors： Abadir R

更新日期：1976-01-01 00:00:00

abstract：:High-quality data support multiple clinical benefits of integrating palliative care into routine oncology care. Though these data come largely from the medical oncology literature, data from surgical oncology populations support similar associations between palliative care integration and improved clinical outcomes, a...

journal_title：Journal of surgical oncology

authors： Moroney MR,Lefkowits C

更新日期：2019-07-01 00:00:00

abstract：:Neoadjuvant systemic breast cancer therapy is the administration of systemic therapy to eligible breast cancer patients prior to surgery. This treatment modality was developed out of necessity to downstage inoperable tumors, but it has evolved into a tool for breast conservation surgery. The neoadjuvant approach is al...

journal_title：Journal of surgical oncology

authors： Makhoul I,Kiwan E

更新日期：2011-03-15 00:00:00

abstract：:Lymph node involvement in colorectal cancer, one of the most important prognostic factors, can be sometimes underestimated. In this study the authors report the results of two different techniques of specimen preparation and examination. In 240 patients (Group I), histologic examination was performed using a conventio...

journal_title：Journal of surgical oncology

authors： Crucitti F,Doglietto GB,Bellantone R,Sofo L,Bossola M,Ratto C,Nucera P,Silvestri E,Crucitti A,Vecchio FM

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The object of the current study was to review the outcomes of hepatic resection for hepatocellular carcinoma (HCC) ≥ 10 cm. METHODS:Between 1995 and 2007, fifty-three patients with HCC ≥ 10 cm underwent hepatic resection, and clinical data were compared to those of patients with non-surgical treatment (n = ...

journal_title：Journal of surgical oncology

authors： Yamashita Y,Taketomi A,Shirabe K,Aishima S,Tsuijita E,Morita K,Kayashima H,Maehara Y

更新日期：2011-09-01 00:00:00

abstract：:Bile salts appear to be important promoters of colon carcinogenesis. This study was designed to assess the importance of the fecal stream in cholic acid-induced colon tumor promotion. Male Sprague-Dawley rats underwent transverse colostomy after induction with dimethylhydrazine (DMH) and the excluded distal colon was ...

journal_title：Journal of surgical oncology

authors： Tempero MA,Zetterman RK

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We analyzed the clinicopathologic characteristics and tumor biology of metachronous bilateral breast carcinoma with regard to p53, HER2 and hormone receptor status. METHODS:A consecutive series of 54 female metachronous bilateral breast carcinoma patients treated at the National Cancer Center...

journal_title：Journal of surgical oncology

authors： Matsuo K,Fukutomi T,Tsuda H,Akashi-Tanaka S,Shimizu C,Hasegawa T

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The optimal extent of lymphadenectomy in patients with esophageal cancer is controversial. This study aimed to examine the therapeutic value of lymph node (LN) dissection for each LN station in patients with esophageal squamous cell carcinoma (ESCC) who receive neoadjuvant chemotherapy. METHO...

journal_title：Journal of surgical oncology

authors： Miyata H,Yamasaki M,Makino T,Miyazaki Y,Takahashi T,Kurokawa Y,Nakajima K,Takiguchi S,Mori M,Doki Y

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Use of hospice services among patients with pancreatic cancer following pancreatic resection remains unknown. METHODS:Patients with pancreatic cancer who underwent resection were identified in the Medicare Standard Analytic Files. Outcomes included overall hospice use, early hospice enrollment (≥4 weeks bef...

journal_title：Journal of surgical oncology

authors： Paredes AZ,Hyer JM,Tsilimigras DI,Mehta R,Sahara K,White S,Dillhoff ME,Ejaz A,Cloyd JM,Pawlik TM

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study aims to investigate the surgical outcomes observed in robotic transperitoneal aortic lymphadenectomy (AL) in gynecological cancer patients. METHODS:Retrospective data were collected and analyzed on 71 patients undergoing robotic surgical procedures for gynecological cancers, includi...

journal_title：Journal of surgical oncology

authors： Gallotta V,Federico A,Gaballa K,D'Indinosante M,Conte C,Giudice MT,Naldini A,Lodoli C,Rotolo S,Gallucci V,Tortorella L,Romanò B,Scambia G,Ferrandina G

更新日期：2019-03-01 00:00:00

abstract：:The clinical records and treatment results of 163 patients with Hodgkin's disease, who were seen at Ellis Fischel State Cancer Hospital (EFSCH) between 1940 and 1971, were reviewed and analyzed. More than 200 clinical and histological variables were recorded for each case of Hodgkin's disease, including details of rad...

journal_title：Journal of surgical oncology

authors： Say C,Lee YT,Hori J,Spratt JS Jr

更新日期：1975-01-01 00:00:00

abstract：:Tumor markers such as carcinoembryonic antigen (CEA) and CA19-9 were analyzed as response indicators and prognostic factors in advanced colorectal carcinoma. Eighty-five patients participated in a phase II chemotherapy study from October 1984 to July 1990. A three-drug schedule was administered including low dose epir...

journal_title：Journal of surgical oncology

authors： Kouri M,Pyrhönen S,Kuusela P

更新日期：1992-02-01 00:00:00

abstract：:The result of percutaneous superfine-needle aspiration biopsy in 100 patients with intrathoracic lesions guided by simulator is reported. The success rate of aspiration biopsy was 94%, and no major complication was observed. The method of localization by simulator had advantages such as accuracy in localization, no li...

journal_title：Journal of surgical oncology

authors： Liu GS,Wu YL,Zeng CG,Yang MT,Cai YH,Rong TH,Huang ZF,Liang XM

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to develop a prediction model for the presence and location of lymph node metastasis (LNM) in early gastric cancer. METHOD:We reviewed medical records of 4 929 patients who underwent radical gastrectomy for early gastric cancer. Variables of age, sex, lymphatic invasion, depth of i...

journal_title：Journal of surgical oncology

authors： Kim SM,Lee H,Min BH,Kim JJ,An JY,Choi MG,Bae JM,Kim S,Sohn TS,Lee JH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Some cases of mass-forming intrahepatic cholangiocarcinoma (ICC) are diagnosed as hepatocellular carcinoma (HCC) based on preoperative imaging and clinical findings. We investigated the backgrounds of such cases. METHODS:Sixty-seven patients with mass-forming ICC underwent surgery from 1980 to 2002. Twenty-...

journal_title：Journal of surgical oncology

authors： Yamamoto M,Ariizumi S,Otsubo T,Katsuragawa H,Katagiri S,Nakano M,Takasaki K

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Multiple free tissue transfer from the same donor site is not well described for microsurgical head and neck reconstruction. METHODS:Between (8/2011 and 11/2012), 103 patients received 103 free ALT flaps for head and neck reconstruction; flaps were called first-time ALT flaps. Intra-operative findings were ...

journal_title：Journal of surgical oncology

authors： Al Deek NF,Liao CT,Huang SF,Kan CJ,Chang KP,Fang KH,Tsao CK

更新日期：2017-03-01 00:00:00

abstract：:Sixteen consecutive patients entered in a prospective study of non-neurogenic soft tissue tumours had lesions in the axilla. Delayed diagnosis and inappropriate biopsy prior to referral to a surgical oncologist were frequent findings. Sarcoma and fibromatosis were diagnosed in 14 cases, and the approaches used for the...

journal_title：Journal of surgical oncology

authors： Bell RS,Ready J,Hudson A,O'Sullivan B,Mahoney J,Richards R,Davis A,Fornasier VL

更新日期：1989-10-01 00:00:00

abstract：:A unique epileptic patient with intracranial neoplasm is reported in which a meningioma with lipomatous and osseous components was found associated with cerebral arteriovenous malformation at the same location in the right frontal lobe. The development of the leptomeningeal neoplasm may have been influenced by the und...

journal_title：Journal of surgical oncology

authors： Kasantikul V,Brown WJ

更新日期：1984-05-01 00:00:00