The Changing Landscape in Supporting Preterm Infants at Birth.

abstract：BACKGROUND:Neonatal reference values of gallbladder size have been assessed in healthy newborns with enteral feeding regimen. Their applicability to critically ill patients under total parenteral nutrition (TPN) remains to be questioned. OBJECTIVE:Our aim was to evaluate the impact of short-term TPN versus enteral nut...

journal_title：Neonatology

authors： Schmidt B,Roth B,Stützer H,Benz-Bohm G

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The lack of normative newborn serum ferritin concentration data between 23 and 41 weeks has led to difficulty in establishing the incidence and degree of abn...

journal_title：Neonatology

authors： Siddappa AM,Rao R,Long JD,Widness JA,Georgieff MK

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE:To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS:From a retrospective cohort of preterm infants with a gestationa...

journal_title：Neonatology

authors： Ten Hove CH,Vliegenthart RJ,Te Pas AB,Brouwer E,Rijken M,van Wassenaer-Leemhuis AG,van Kaam AH,Onland W

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Therapeutic hypothermia (HT) is the standard treatment for newborns after perinatal asphyxia. Preclinical studies report that HT is more effective when started early. METHODS:Eighty cooled newborns were analyzed and grouped according to when cooling was started after birth: early (≤180 min) or late (>181 min...

journal_title：Neonatology

authors： Thoresen M,Tooley J,Liu X,Jary S,Fleming P,Luyt K,Jain A,Cairns P,Harding D,Sabir H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES:The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine tempe...

journal_title：Neonatology

authors： Ng PL,Carlisle T,Ly M,Morris SA

更新日期：2017-01-01 00:00:00

abstract：:Transcutaneous electromyography of the diaphragm (dEMG) is a noninvasive and easy applicable tool to measure the electrical activity of the diaphragm. dEMG monitoring has recently been introduced in the neonatal intensive care unit as a novel cardiorespiratory monitor providing direct information on diaphragmatic brea...

journal_title：Neonatology

authors： Kraaijenga JV,Hutten GJ,de Jongh FH,van Kaam AH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Nosocomial infections endanger preterm infants. OBJECTIVE:The aim of the present controlled randomized trial was to investigate whether Bifidobacterium lactis reduces the incidence of nosocomial infections in infants with very low birth weight (VLBW; <1,500 g) <30 weeks of gestation. PATIENTS AND METHODS:I...

journal_title：Neonatology

authors： Mihatsch WA,Vossbeck S,Eikmanns B,Hoegel J,Pohlandt F

更新日期：2010-01-01 00:00:00

abstract：:Ductus arteriosus and foramen ovale were described by Galen without understanding their functions. His beliefs in soul localization and spiritization within the left ventricle established religious pneumatology which became a theological need in the Middle Ages. Pulmonary transit was recognized by Servetus and Colombo...

journal_title：Neonatology

authors： Obladen M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Newborns are susceptible to inflammatory diseases due to defects in clearing activated immune cells from tissues. Therefore, mechanisms have likely evolved to protect neonates from leukocyte-mediated cytotoxicity. Bilirubin has antioxidant activity, and it is possible that it also exerts effects on cellular ...

journal_title：Neonatology

authors： Weinberger B,Archer FE,Kathiravan S,Hirsch DS,Kleinfeld AM,Vetrano AM,Hegyi T

更新日期：2013-01-01 00:00:00

abstract：:Volume resuscitation (VR) for the treatment of newborn shock is a rare but potentially lifesaving intervention. Conducting clinical studies to assess the effectiveness of VR in the delivery room during newborn stabilization is challenging. We review the available literature and current management guidelines to determi...

journal_title：Neonatology

authors： Finn D,Roehr CC,Ryan CA,Dempsey EM

更新日期：2017-01-01 00:00:00

abstract：:We describe a case highlighting several controversial and important topics regarding neonatal cardiopulmonary resuscitation (CPR). Current neonatal guidelines recommend a 3:1 compression:ventilation ratio; however, the most effective ratio of delivering chest compressions (CC) remains controversial. We report a case o...

journal_title：Neonatology

authors： Li ES,Cheung PY,Pichler G,Aziz K,Schmölzer GM

更新日期：2014-01-01 00:00:00

abstract：:This paper describes a neonate with type II Gaucher disease. The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure. Electron microscopy of the skin revealed lamellar body contents in the stratum corneum interstices, appearances consider...

journal_title：Neonatology

authors： Haverkaemper S,Marquardt T,Hausser I,Timme K,Kuehn T,Hertzberg C,Rossi R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Higher patient-to-nurse ratios and nursing workload are associated with increased mortality in the adult intensive care unit (ICU). Most neonatal ICUs (NICUs) in the United Kingdom do not meet national staffing recommendations. The impact of staffing on outcomes in the NICU is unknown. OBJECTIVE:To determin...

journal_title：Neonatology

authors： Sherenian M,Profit J,Schmidt B,Suh S,Xiao R,Zupancic JA,DeMauro SB

更新日期：2013-01-01 00:00:00

abstract：:There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a noninvasive ventilation approach with a strategy for surfac...

journal_title：Neonatology

authors： Blennow M,Bohlin K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Sustained lung inflation (SLI) applied at birth has been demonstrated to lead to clearance of lung fluid and achievement of a precocious functional residual capacity in animal studies. OBJECTIVES:To verify if the application of SLI in preterm infants at birth may reduce the need for mechanical ventilation a...

journal_title：Neonatology

authors： Lista G,Fontana P,Castoldi F,Cavigioli F,Dani C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Delayed cord clamping (DCC) improves placental transfusion and increases blood volume in preterm infants when compared with immediate cord clamping (ICC). However, evidence to support DCC in multiple-birth preterm infants is still lacking. OBJECTIVE:To compare the outcomes of ICC versus DCC in preterm infan...

journal_title：Neonatology

authors： Ruangkit C,Bumrungphuet S,Panburana P,Khositseth A,Nuntnarumit P

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Small for gestational age (SGA) neonates are at increased risk of mortality and morbidity, including necrotizing enterocolitis (NEC), but detailed information on the incidence and risk factors of NEC in SGA neonates is lacking. OBJECTIVE:This study aims to estimate the incidence of NEC in a large cohort of ...

journal_title：Neonatology

authors： Ree IM,Smits-Wintjens VE,Rijntjes-Jacobs EG,Pelsma IC,Steggerda SJ,Walther FJ,Lopriore E

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Gene expression profiling of the salivary supernatant is emerging as a new and important source of real-time, systemic, biological information. However, existing technologies prevent RNA extraction of small quantities found in neonatal salivary supernatant. OBJECTIVE:The aim of this study was to develop tec...

journal_title：Neonatology

authors： Dietz JA,Johnson KL,Wick HC,Bianchi DW,Maron JL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

journal_title：Neonatology

authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Premature infants with severe bronchopulmonary dysplasia (sBPD) are at risk of pulmonary hypertension (PH). Serum brain natriuretic peptide (BNP) is used to predict disease severity in adult PH. Its diagnostic utility in sBPD-associated PH is unknown. OBJECTIVE:The aim of this paper was to determine the acc...

journal_title：Neonatology

authors： Avitabile CM,Ansems S,Wang Y,Fraga MV,Kirpalani HM,Zhang H,Mercer-Rosa L,Jensen EA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The probabilities of survival and survival without major brain damage (MBD) are low in newborns at the limit of viability. Survival without MBD constitutes a major concern for parents and professionals. OBJECTIVES:To know the probabilities of survival without MBD in newborns ≤26 weeks' gestational age (GA) ...

journal_title：Neonatology

authors： García-Muñoz Rodrigo F,Urquía Martí L,García Hernández JÁ,Figueras Aloy J,García-Alix Pérez A,SEN1500 Network of the Spanish Neonatal Society.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Long-gap esophageal atresia (LGEA) may have clinical and syndromic presentations different from those of esophageal atresia (EA) that affects shorter segments of the esophagus (non-LGEA). This may suggest unique underlying developmental mechanisms. OBJECTIVES:We sought to characterize clinical differences b...

journal_title：Neonatology

authors： Bairdain S,Zurakowski D,Vargas SO,Stenquist N,McDonald M,Towne MC,Miller DT,Jennings RW,Kantor DB,Agrawal PB

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Alveolar development and lung parenchymal simplification are not well characterized in vivo in neonatal patients with respiratory morbidities, such as bronchopulmonary dysplasia (BPD). Hyperpolarized (HP) gas diffusion magnetic resonance imaging (MRI) is a sensitive, safe, nonionizing, and noninvasive biomar...

journal_title：Neonatology

authors： Higano NS,Thomen RP,Quirk JD,Huyck HL,Hahn AD,Fain SB,Pryhuber GS,Woods JC

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Preterm infants with signs of poor perfusion are often treated with volume expansion, although evidence regarding its effect on cerebral perfusion is lacking. Moreover, the effect is questionable in preterm infants with an adequate cerebrovascular autoregulation (CAR). A useful measure to assess perfusion is...

journal_title：Neonatology

authors： Kooi EM,van der Laan ME,Verhagen EA,Van Braeckel KN,Bos AF

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Lipid metabolism is vital to fetal development and cardiometabolic health and the final weeks of gestation are known to be a time of intense metabolic activity. New techniques such as lipidomics allow investigation of a complex lipidomic profile in infants. OBJECTIVES:This research aimed to (1) describe var...

journal_title：Neonatology

authors： McCloskey K,De Livera AM,Collier F,Ponsonby AL,Carlin JB,Vuillermin P,Mellett NA,Jayawardana K,Weir JM,Blangero J,Curran JE,Burgner D,Meikle PJ,BIS investigator group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...

journal_title：Neonatology

authors： EL-Khuffash A,McNamara PJ,Lapointe A,Jain A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Nasal continuous positive airway pressure (NCPAP) is a well-studied treatment for respiratory problems in preterm infants. However, the best strategy for NCPAP weaning is unknown. OBJECTIVE:We aimed to compare the success of progressive pressure wean versus sudden wean for discontinuation of NCPAP in preter...

journal_title：Neonatology

authors： Lemieux-Bourque C,Piedboeuf B,Fontela PS,Bornais K,Beltempo M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...

journal_title：Neonatology

authors： Yin X,Zhao J,Jiang H,Li L,Jiang J,Xi H,Peng X,Yin X,Shi X,Zhang L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Recent studies indicate an increasing use of less invasive surfactant administration. Different techniques have been shown with distinct risks and benefits. The aim of this study was to develop a new method that simplifies this procedure. OBJECTIVES:An applicator was developed and tested on a manikin to mak...

journal_title：Neonatology

authors： Maiwald CA,Neuberger P,Vochem M,Poets C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown. OBJECTIVES:To elucidate the current utilization rate of inhaled corticosteroids in the prevention and th...

journal_title：Neonatology

authors： Maas C,Poets CF,Bassler D

更新日期：2010-01-01 00:00:00