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Membrane-Active Rhamnolipids Overcome Aminoglycoside Resistance.

Abstract：

:In this issue of Cell Chemical Biology, Radlinski et al. (2019) identify Pseudomonas-derived rhamnolipids that potentiate aminoglycoside antibiotics in the eradication of antibiotic-tolerant bacterial phenotypes. Microbial physiological and mechanistic studies indicate that rhamnolipids permeabilize S. aureus membrane and drive the uptake of aminoglycosides that is independent of proton-motive force.

journal_name

Cell Chem Biol

journal_title

Cell chemical biology

authors

Yarlagadda V,Wright GD

doi

10.1016/j.chembiol.2019.09.015

subject

Has Abstract

pub_date

2019-10-17 00:00:00

pages

1333-1334

issue

10

eissn

2451-9456

issn

2451-9448

pii

S2451-9456(19)30320-4

journal_volume

26

pub_type

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