More than One Way to Skin a Catalyst.

Abstract:

:In this issue of Cell Chemical Biology, Diaz et al. (2017) report a strategy to achieve temporal, spatial, and stoichiometric control over the protein kinase cAbl in living cells. They achieve this by splitting cAbl into two inactive fragments that form an active kinase upon small molecule addition, potentially providing a general way to probe the wiring of signal transduction networks.

journal_name

Cell Chem Biol

journal_title

Cell chemical biology

authors

Michnick SW

doi

10.1016/j.chembiol.2017.10.004

subject

Has Abstract

pub_date

2017-10-19 00:00:00

pages

1196-1197

issue

10

eissn

2451-9456

issn

2451-9448

pii

S2451-9456(17)30361-6

journal_volume

24

pub_type

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