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Fighting Kinase Drug Resistance with Caspase Activators.

Abstract：

:Kinase inhibitors are effective cancer therapies. Unfortunately, drug resistance emerges in response to kinase inhibition leading to loss of drug efficacy. In this issue of Cell Chemical Biology, Peh et al. (2018) demonstrate that caspase activators effectively delay onset of resistance to kinase inhibitors and are excellent co-therapeutics for a number of tumor types.

journal_name

Cell Chem Biol

journal_title

Cell chemical biology

authors

Hardy JA

doi

10.1016/j.chembiol.2018.08.001

subject

Has Abstract

pub_date

2018-08-16 00:00:00

pages

927-928

issue

8

eissn

2451-9456

issn

2451-9448

pii

S2451-9456(18)30267-8

journal_volume

25

pub_type

评论,杂志文章

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