Pathogen Interference: Targeting Virulence Factors to Tackle Intracellular Microbes.

Abstract:

:Infections with Salmonella enterica pose a challenge for antibiotic treatment. In this issue of Cell Chemical Biology, Tsai et al. use a chemical genomics approach to identify dephostatin as an inhibitor of intracellular Salmonella virulence in vitro and in vivo by targeting the two-component systems SsrA-SsrB and PmrB-PmrA.

journal_name

Cell Chem Biol

journal_title

Cell chemical biology

authors

Lee MH,Nuccio SP,Raffatellu M

doi

10.1016/j.chembiol.2020.06.017

subject

Has Abstract

pub_date

2020-07-16 00:00:00

pages

765-767

issue

7

eissn

2451-9456

issn

2451-9448

pii

S2451-9456(20)30240-3

journal_volume

27

pub_type

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