Abstract：
OBJECTIVES:To evaluate harmful interactions between antidepressants and medications used in treatment of cardiovascular disorders. METHODS:The analysis of 66 cases of adverse reactions with a clinical picture indicating, to a degree that is probable or certain, that they were the result of the combination of antidepressant with cardiovascular medication. RESULTS:The most common side effect (n = 25, 37.9%) was bradycardia (and other side effects of beta blockers) as a consequence of addition of metoprolol or propranolol to SSRI or bupropion. In one case combination of fluoxetine with propranolol resulted in cardiac arrest. We observed 8 cases of intensified side effects of amlodipine (swelling of lower limbs, headaches) after its combination with: fluoxetine, sertraline and paroxetine, and occurrence of myalgia, elevated aminotransferase levels, polyuria and hypotension after combination of lercanidipine with some of the SSRIs. We also found i.a. worsening of propafenone tolerance in combination with venlafaxine or bupropion, 2 cases of granulopenia associated with duloxetine-propafenone combination, 2 cases of hemorrhagic complications associated with the combination of vortioxetine-warfarin, 1 case of hyponatremia associated with the combination of vortioxetine and hydrochlorothiazide, as well as antagonizing clonidine's hypotensive effect by mirtazapine, and peripheral thrombosis following the combination of warfarin with trazodone. CONCLUSIONS:Because of ahigh risk of interactions and related adverse effects, especially in older patients, each decision regarding combination of a particular antidepressant with a medication used in treatment of cardiovascular disorders should be preceded by a detailed analysis of safety and risk-benefit ratio, and also be associated with the search for the safest, alternative combinations of the above-mentioned medications.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Woroń J,Siwek M,Gorostowicz Adoi
10.12740/PP/OnlineFirst/96286subject
Has Abstractpub_date
2019-10-30 00:00:00pages
977-995issue
5eissn
0033-2674issn
2391-5854pii
96286journal_volume
53pub_type
杂志文章abstract：:58 men treated for epilepsy, average age 38.5, and their 100 children aged on average 11.2 were subjected to psychological tests adapted to patients age. Mental effectiveness test (IQ) were based on WHO criteria for Wechsler Scale. Among the epileptic patients 77.6% presented normal IQ tests results, whereas 5.6% were...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:The paper is an empirical verification of a thesis according to which inter-family factors decide, to a large extent, about the psychiatric hospitalization of patients suffering from schizophrenia. On examining a population of 48 patients hospitalized for the first time because of schizophrenia and their families, it ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Mild cognitive impairment (MCI) is present in on average one-fourth of Parkinson's disease (PD) patients with no dementia diagnosis. Only recently has PD-MCI been treated as a new diagnostic entity. In 2012, unified criteria were adopted which allow both diagnosing MCI in Parkinson's disease (PD-MCI) and further class...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to prepare the Polish adaptation of the Young Schema Questionnaire S3-PL. The scale is a self-assessment tool designed to measure 18 early maladaptive schemas. METHODS:The sample consists of 1,529 adults (927 women and 585 men), aged 18-85 years (mean age was 32 years), from non-cli...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/OnlineFirst/76541
更新日期：2018-08-24 00:00:00
abstract：:The approach towards the issues of depression and mental health problems of mentally disabled persons is discussed in the paper. The author discussed the various susceptibilities, resistances and typical mental health disturbances of mentally disabled persons as well as their diagnostic criteria and methods of measuri...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVES:Verification of the level of social support perception and sense of life in patients with anxiety disorder and healthy people; evaluation of the relationship between these variables. METHODS:The Social Support Questionnaire short version (F-SozU K-22) by G. Sommer and T. Fydrich and the Life Attitude Profil...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/81447
更新日期：2019-04-30 00:00:00
abstract：BACKGROUND:Severe asthma, a dangerous, life-threatening lung disease is often comorbid with psychiatric problems. They in turn, could be a cause of bad asthma treatment outcome. AIM:The purpose of the study was to assess the prevalence of panic disorder and depression among patients with severe asthma. Defence style, ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVES:Research results indicate that possibility of building a therapeutic relationship in schizophrenia treatment facilitates better functioning, more effective reduction in psychotic symptoms and fulfillment of patients' personal goals. The aim of the present study was to investigate whether patients systematica...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/31505
更新日期：2015-03-01 00:00:00
abstract：:The aim of the work was to establish the usefulness of alcoholism scales enclosed in MMPI for the evaluation of risk of alcohol dependence among college students. The results of 1255 college students from different schools and various years of studium were reviewed. The risk of alcohol dependence was established by an...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:Premorbid adjustment of 100 hospitalized adolescent patients and its correlation with some clinical variables was assessed and compared with a group of 100 healthy adolescents. The hospitalized group of patients was divided into four diagnostic subgroups according to the diagnostic criteria of ICD 9: psychoses, neuros...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：AIM:The author examined psychiatrically a group of 106 patients with difficult asthma and 100 patients with aspirin-induced asthma. The special interest of the study were links between defence mechanisms used by women and men from both groups and severity of their panic and depressive symptoms. METHODS:106 consecutive...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:Investigations of cerebral blood flow and metabolism provide interesting data concerning specific brain regions involved in depression. The objective of this paper is to present to Polish readers results of studies using PET in patients with depression. Provocation of transient sadness in healthy subjects during clini...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-01 00:00:00
abstract：AIM:Construction of a questionnaire describing personality traits connected to the occurrence and persistence of neurotic disorders. METHOD:Responses of 794 patients (before treatment) and 520 persons from the control group on items of the constructed personality questionnaire and the symptom checklist "0". Analyses o...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：:The paper presents a review of recent data on research and clinical significance of gating of the P50 component of the auditory evoked potentials (AEP). Information filters are a necessary element for the proper functioning of the brain. It appears as though they have an important role in the information-transfer mech...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-09-01 00:00:00
abstract：:Ketamine is a rapid-acting anaesthetic agent which has been used for over 40 years. It is an antagonist of N-methyl-D-aspartate (NMDA) receptors and agonist of mu and sigma opiate receptors. Ketamine acts through inhibition of sensory parts in the brain and stimulation of the limbic system and optic thalamus. The most...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:The paper presents the assessment of liver pathology based on clinical examinations, biochemical findings and abdominal ultrasound examination with colour Doppler modalities in a group of 40 alcohol dependent patients. Special regard was paid to the liver, it is size, echogenecity, homogeneity and flow patterns in the...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVES:Internet Addiction Disorder can be defined as "the inability of individuals to control their internet use, resulting in marked distress and/or functional impairment in daily life." It carries the same social aftermath of impulse control and substance misuse disorders such as loss of control, craving and with...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/32500
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:Having the opportunity to work has been found meaningful for individuals suffering from severe mental illness, in order to boost their self-esteem, provide a sense of control over their lives and of belonging to a community. There are no studies in Polish literature on the process of recovery from schizophre...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/44238
更新日期：2016-01-01 00:00:00
abstract：:Zinc is an important modulator of glutaminergic transmission. Recent data indicate that pathology of amino-acidergic neurotransmission may contribute to mood disorders and may be involved in antidepressant-like actions in laboratory models. A growing body of evidence implicates a derangement of zinc homeostasis in moo...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-09-01 00:00:00
abstract：:The paper presents a critical review regarding the pathogenesis of schizophrenia. The neurodevelopmental theory which is now mostly recognized, needs some explanations, some elements of neurodegenerative theory are revisited. The developmental factors are confirmed as important in the pathogenesis of schizophrenia, bu...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-03-01 00:00:00
abstract：:The paper describes a specific form of Oedipus complex that may occur as a result of sexual abuse. The author emphasises that formation of the image of one parent due to actual sexual abuse and the activity of the child's (patient's) own iscestual impulses causes that the second parent is experienced as a terrorizing ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:Psychometric evaluation of reliability and usefulness of the Polish version of the CESD-R - a revised version of the CES-D - screening test for depression. METHODS:In an online survey the CESD-R and the Beck Depression Inventory were applied to 260 participants (men and women). Reliability was assessed with...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/61614
更新日期：2016-12-23 00:00:00
abstract：:The aim of the second part of our work associated with psychopharmacotherapy during pregnancy and lactation is to present current guidelines of expert-groups concerning the rules of treating affective disorders and actual data about the spreading of these disorders pre- and perinatal effects of drugs used, the classif...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：:The authors present the review of basic knowledge about aetiological mechanisms of painful symptoms, especially chronic pain and give a detailed description of links between pain and depression (psychologic, biological). Depressive disorders and chronic pain often coexist. Data of studies show that 30-84% of patients ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:Monitored treatment of a depressed phase of unipolar affective disorder was conducted in 11 female patients receiving imipramine and in 12 females taking amitriptyline. Patients were randomly assigned to one of the drug and in 6 patients the drugs were switched because of the lack of response to the first used compoun...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-05-01 00:00:00
abstract：:Considerations, concerning legal obligation to psychiatric treatment in case of criminal offenders declared as insane by court, are presented in the paper. Necessity of some changes in the legal system is pointed out. It is suggested that, after preventive measures in the form of compulsory psychiatric hospitalization...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to investigate the general knowledge and attitudes towards ECT among Polish students, including students of medical faculties. Furthermore, the influence of pop-culture on society's opinion about ECT was investigated. METHODS:For this purpose, 1,370 students have been examined with ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/109157
更新日期：2020-06-30 00:00:00
abstract：:Neuropsychiatric symptoms are commonly related to interferon alpha treatment. The paper summarises the current knowledge about their aetiology, course, and treatment. Interferon alpha is a cytokine with antiviral and antineoplasmatic activity. It is commonly used in the treatment of chronic hepatitis C and B, malignan...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：:In this paper we review previous research, suggesting a link between depressive symptoms and poor prognosis in cancer patients. The possibility, to identify an association between depressed mood and poorer outcomes and survival in haematological malignancies seems to be very interesting. We shortly describe acute leuk...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:The military service of Polish soldiers on missions abroad began in 1953. Many years of experience of the Polish army as well as the armed forces of other countries show that being in a mission area has a significant impact on soldiers' mental health. Soldiers experience problems with anxiety disorders, depr...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/OnlineFirst/75666
更新日期：2018-10-27 00:00:00
