Effects of sucrose on carbohydrate and lipid metabolism in NIDDM patients.

Abstract:

:Recently, there has been increasing interest toward the liberalization of sucrose in the diets of individuals with non-insulin-dependent diabetes mellitus (NIDDM). However, there is evidence from several well-controlled prospective studies demonstrating that the consumption of moderate amounts of sucrose may result in hyperglycemia, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia, and reduced high-density lipoprotein cholesterol concentrations. The fact that not all studies demonstrate these deleterious effects does not negate the positive data. The magnitude of the deleterious effects will probably vary with individual patients, baseline status, and amount of sucrose. Because these metabolic abnormalities are most disturbed in diabetes and are associated with increased risk of coronary artery disease, it would seem reasonable to continue to advise patients with NIDDM to limit sucrose consumption, at least until available data would allow us to predict in which individuals and at what level of sucrose consumption these adverse metabolic effects would not be present.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Hollenbeck CB,Coulston AM,Reaven GM

doi

10.2337/diacare.12.1.62

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

62-6; discussion 81-2

issue

1

eissn

0149-5992

issn

1935-5548

journal_volume

12

pub_type

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