Abstract:
OBJECTIVE:The role of oestrogen in craniofacial growth still remains unclear. Therefore, the present study aimed to assess the effect of oestrogen deficiency on maxilla and mandible dimensions. SETTING AND SAMPLE POPULATION:The study was conducted at the Department of Pediatric Dentistry at the School of Dentistry of Ribeirão Preto, University of São Paulo, and used forty female Wistar rats. MATERIAL AND METHODS:Ovariectomy (OVX) and placebo surgery (Sham) were performed when animals were twenty-one days old (prepubertal stage). Dimensions of the maxilla and mandible were assessed by craniometric analysis using radiographs, during and after puberty of the animals (45 and 63 days old, respectively). Quantitative real-time PCR and immunohistochemical analyses were performed to determine the expression and localization, respectively, of oestrogen receptor alpha (ERα) and oestrogen receptor beta (ERβ) in different growth sites of the evaluated structures at puberty. The differences between the groups for each outcome were evaluated using the t test with an established alpha error of 5%. RESULTS:There were significant differences between the OVX and Sham groups for horizontal and vertical linear measurements in the maxilla and the mandible at both pubertal and post-pubertal stages (P < .05). The ovariectomized rats showed significantly greater measures for all dimensions assessed. No differences in gene expression of ERα and ERβ were identified at the different growth sites between the OVX and Sham groups (P > .05). Immunohistochemical analyses revealed the presence of both oestrogen receptors in osteoblasts and chondrocytes in the midpalatal suture and mandibular condyle, respectively, in the OVX and Sham groups. CONCLUSION:Our results suggest that oestrogen deficiency from the prepubertal stage might increase the growth of the maxilla and mandible in female rats.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Omori MA,Marañón-Vásquez GA,Romualdo PC,Martins Neto EC,Stuani MBS,Matsumoto MAN,Nelson-Filho P,Proff P,León JE,Kirschneck C,Küchler ECdoi
10.1111/ocr.12376subject
Has Abstractpub_date
2020-08-01 00:00:00pages
342-350issue
3eissn
1601-6335issn
1601-6343journal_volume
23pub_type
杂志文章abstract:UNLABELLED:AUTHOR: Shen G Objective -This review was compiled to explore the role of type X collagen in growth, development and remodeling of articular cartilage by elucidating the linkage between the synthesis of this protein and the phenotypic changes in chondrogenesis and the onset of endochondral ossification. DES...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2004.00308.x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:The present study aimed to analyse palatal changes due to rapid maxillary expansion (RME) by using modern geometric morphometric analysis (GMA) on 3D models. SETTINGS AND SAMPLE POPULATION:Forty children with posterior crossbite and maxillary deficiency were selected for this study. Twenty children were trea...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12387
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12122
更新日期:2016-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2011.01525.x
更新日期:2011-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2006.00340.x
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12061
更新日期:2015-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12141
更新日期:2017-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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doi:10.1111/j.1601-6343.2005.00320.x
更新日期:2005-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01494.x
更新日期:2010-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2009.01475.x
更新日期:2010-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
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更新日期:2019-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
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更新日期:2007-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2005.00332.x
更新日期:2005-08-01 00:00:00
abstract::Antimicrobial orthodontic adhesives aim to reduce white spot lesions' incidence in orthodontic patients, but they should not jeopardizing its properties. Systematic review and meta-analysis were performed to answer the question whether the association of antimicrobial agents with orthodontic adhesives compromises its ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ocr.12100
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To assess total Streptococci (TS) counts and biofilm mass over tooth-tissue-borne palatal expander (TTBPE), as well as the effect of chlorhexidine (CHX) mouth rinse on these variables. DESIGN:A cross-sectional study design employed clinical procedures and laboratorial techniques. SETTING AND SAMPLE POPULAT...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2007.00418.x
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To detect changes in mandibular growth between a historical group (HG) from the American Association of Orthodontics Foundation Craniofacial Growth Legacy Collection (AAOF Legacy) and a contemporary group (CG) of normodivergent or hypodivergent Class II untreated subjects. SETTING AND SAMPLE POPULATION:The ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12321
更新日期:2019-11-01 00:00:00
abstract::In cranial sutural samples derived from five children with premature cranial suture fusion we have performed immunostaining for the urokinase plasminogen activator (uPA) and urokinase receptor (uPAR). We have found a strong reactivity for cell- or matrix-bound uPA and uPAR in the sutural connective tissue and associat...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2002.50101.x
更新日期:2002-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2012.01546.x
更新日期:2012-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2008.00434.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To review the historic context for digital imaging in dentistry and to outline the fundamental issues related to digital imaging modalities. CONTEXT:Digital dental X-ray images can be achieved by scanning analog film radiographs (secondary capture), with photostimulable phosphors, or using solid-state detec...
journal_title:Orthodontics & craniofacial research
pub_type: 历史文章,杂志文章
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更新日期:2003-01-01 00:00:00
abstract::Repair of tooth supporting alveolar bone defects caused by periodontal and peri-implant tissue destruction is a major goal of reconstructive therapy. Oral and craniofacial tissue engineering has been achieved with limited success by the utilization of a variety of approaches such as cell-occlusive barrier membranes, b...
journal_title:Orthodontics & craniofacial research
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更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:To evaluate the reliability of a new technique for measuring 3D-scanned orthodontic cast models with cross-section planes using teledent, a new software, developed at Technion - for the purpose of this research. EXPERIMENTAL VARIABLE:Thirty orthodontic plaster models were divided into three equal groups acc...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00417.x
更新日期:2008-05-01 00:00:00
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更新日期:2021-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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更新日期:2016-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:To study the efficacy of tenoxicam for pain control, its potential for preemptive analgesia, and its influence on the orthodontic movement of upper canine teeth. DESIGN:This was a randomized controlled double-blind cross-over study. The patients were divided into three groups. Two groups received tenoxicam ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2008.01432.x
更新日期:2009-02-01 00:00:00
abstract::The objective of the study was to provide a comprehensive review of the literature describing research done on the stability, adaptation and growth of craniofacial structures following distraction osteogenesis (DO). The design of the study was a literature review of clinical and experimental studies using electronic s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
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更新日期:2009-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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更新日期:2017-06-01 00:00:00