Abstract:
:Advances in precision medicine portend similar progress in orthodontics and will be increasingly harnessed to achieve customized treatment approaches and enhance treatment efficiencies. Our goal is to provide a background on emerging advances in computer technologies and biomedicine and highlight their current and likely future applications to precision orthodontics. A review of orthodontically relevant technologies and advances in pertinent biological research was undertaken. Innovations in computer hardware and software, and 3D imaging technologies offer the ability for customized treatment and biomechanical planning that will be more fully realized within the next few decades. These technologies combined with 3D printing are already being applied to customized appliance fabrication such as aligners and retainers. The future prospects for custom fabrication of orthodontic brackets of appropriate material properties and smart devices are highly desirable and compelling goals. Within biomedicine, the fundamental understanding of cartilage growth and bone biology is currently being tested in animal models to modify mandibular growth and modulate tooth movement, respectively. Some of these discoveries will ultimately have clinical applications in orthodontics including for growth modification, accelerating orthodontic tooth movement, and enhancing anchorage or retention of teeth. Additional genomic and proteomic information will add to further customization of orthodontic diagnosis and treatments. Over the coming decades, precision orthodontics will continue to benefit from advances in many fields and will require the integration of advances in technology, and biomedical and clinical research to deliver optimal, efficient, safe, and reproducible personalized orthodontic treatment.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Jheon AH,Oberoi S,Solem RC,Kapila Sdoi
10.1111/ocr.12171subject
Has Abstractpub_date
2017-06-01 00:00:00pages
106-113eissn
1601-6335issn
1601-6343journal_volume
20 Suppl 1pub_type
杂志文章,评审abstract:OBJECTIVES:To assess total Streptococci (TS) counts and biofilm mass over tooth-tissue-borne palatal expander (TTBPE), as well as the effect of chlorhexidine (CHX) mouth rinse on these variables. DESIGN:A cross-sectional study design employed clinical procedures and laboratorial techniques. SETTING AND SAMPLE POPULAT...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2007.00418.x
更新日期:2008-08-01 00:00:00
abstract::Repair of tooth supporting alveolar bone defects caused by periodontal and peri-implant tissue destruction is a major goal of reconstructive therapy. Oral and craniofacial tissue engineering has been achieved with limited success by the utilization of a variety of approaches such as cell-occlusive barrier membranes, b...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2005.00352.x
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:To test the hypothesis that there are no gender differences in the outcomes of patients with class II malocclusion treated with the headgear-activator Teuscher appliance (HATA). DESIGN:Retrospective, longitudinal SETTING AND SAMPLE POPULATION:Puerto Rico and Scotland, UK. Thirty-one patients requiring corr...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0854.2003.c245.x
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:The aim of this qualitative study was to explore and describe adolescents' experiences of treatment with removable functional appliances. SETTING AND SAMPLE POPULATION:Public Dental Service, Gothenburg, Sweden. MATERIAL AND METHODS:Individual interviews focusing on adolescents' experiences of using a remov...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/ocr.12093
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:Relapse of teeth that have moved during orthodontic treatment is a major clinical issue with respect to the goals of successful treatment. Such relapse is a physiologic response of the supporting tissues to application of force, and is mainly attributed to occlusal instability and increased mechanical tensio...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2009.01463.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To explore asymmetry values of antimeric deciduous tooth crown dimensions in three types of twins: monozygotic (MZ), dizygotic same-sex (DZ) and opposite-sex (OS) vs. single-born controls. SETTING AND SAMPLE POPULATION:Mesiodistal and labio-lingual crown dimensions of second deciduous molars and mesiodistal...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12122
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:1) The objective of this study was to explore radiological signs of intracranial and nuchal ligament calcifications in adult patients with X-linked hypophosphatemia (XLH) compared with controls and 2) to correlate signs of cranial calcifications in XLH patients with the presence of other extra-cranial enthes...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12120
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the reliability of a new technique for measuring 3D-scanned orthodontic cast models with cross-section planes using teledent, a new software, developed at Technion - for the purpose of this research. EXPERIMENTAL VARIABLE:Thirty orthodontic plaster models were divided into three equal groups acc...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00417.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of diabetes on orthodontic tooth movement and orthodontically induced root resorption in rats. SETTING AND SAMPLE POPULATION:Twenty-three 10-week-old male Sprague-Dawley rats divided into control (n = 7), diabetes (n = 9), and diabetes + insulin (n = 7) groups. MATERIALS AND METHO...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12117
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:To test the following two hypotheses: 1) different types of retainers result in distinct levels of biomarkers in gingival crevicular fluid (GCF) and 2) the retainer bonded to all mandibular anterior teeth induces more detrimental outcomes to the periodontium. SETTING AND SAMPLE POPULATION:The Department of ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12129
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To compare the predicted tooth width measurements of permanent canine and premolars from Tanaka-Johnston regression equations and Moyers probability tables with the in situ measurements in a sample of Peruvian adolescents. DESIGN:Cross-sectional. SETTING AND SAMPLE POPULATION:Trujillo, Peru; 248 dental cas...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2003.03251.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:This investigation evaluates the evidence of case-based reasoning (CBR) in providing additional information on the prediction of future Class III craniofacial growth. SETTINGS AND SAMPLE POPULATION:The craniofacial characteristics of 104 untreated Class III subjects (7-17 years of age), monitored with two la...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12466
更新日期:2021-01-08 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare three-dimensional airway changes resulting from mandibular advancement surgery and mandibular advancement surgery with constriction. SETTING AND SAMPLE POPULATION:The University of Michigan School of Dentistry and Medical Center. A total of 42 patients undergoing mandibu...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12292
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:To evaluate whether changes in the concentration of different biomarkers in the gingival crevicular fluid (GCF) can be used to detect the root resorption process in adult or adolescent patients undergoing treatment with a fixed appliance, in comparison with untreated subjects or treated patients not showing ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12329
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Literature is poor of data about the occlusion in children affected by neurofibromatosis type 1 (NF1). This case-control study investigated the occlusal traits in a group of children with NF1. SETTING AND SAMPLE POPULATION:A hundred and fifteen children with NF1 were enrolled; non-NF1 controls were sequenti...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12108
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:To experimentally determine the effects of increased surgical trauma on the rates of tooth movement and apical root resorption. Two surgical techniques for rapid protraction of multi-rooted teeth in foxhound dogs immediately following premolar extraction were compared. METHODS:Split-mouth design to randomly as...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01494.x
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVES:To develop a questionnaire to assess the psychosocial aspects which orthognathic patients considered important regarding their dento-facial deformity. SETTING AND SAMPLE POPULATION:A multicentre, prospective, questionnaire development and validation study based in the UK. MATERIAL AND METHODS:Questionnaire...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12061
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare treatment outcomes with different maxillary protraction methods in patients with skeletal Class III malocclusion resulting from maxillary retrognathia. SETTING AND SAMPLE POPULATION:A total of 55 individuals consisting of 29 females and 26 males with a mean age of 11.4 ± ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12389
更新日期:2020-11-01 00:00:00
abstract::This essay briefly considers some underlying concerns about the direction of clinical research in orthodontics. The field is viewed from a personal perspective as things are now, as they are becoming, and as I believe they should be. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00292.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:To evaluate cephalometrically craniofacial morphology in children with operated sagittal synostosis and to compare the findings with age- and sex-matched controls. SETTING AND SAMPLE POPULATION:Forty-two children (37 boys) with operated primary sagittal synostosis were compared retrospectively with age- and...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12056
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the stability of Natural Head Position (NHP) over time using the 3dMDface System. SETTING AND SAMPLE POPULATION:This was an experimental study. Three-dimensional facial images of 40 students were captured on two different occasions, with an interval of at least two weeks. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12344
更新日期:2020-02-01 00:00:00
abstract::The objective of the study was to provide a comprehensive review of the literature describing research done on the stability, adaptation and growth of craniofacial structures following distraction osteogenesis (DO). The design of the study was a literature review of clinical and experimental studies using electronic s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2009.01452.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To compare the concentration of nickel, chromium and cobalt in oral mucosa cells of patients with and without fixed orthodontic appliances. MATERIALS AND METHODS:A total of 60 patients were included in this study. The control group consisted of 30 patients without any type of fixed orthodontic appliances or ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2008.00414.x
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:To explore centre-level variation in otitis media with effusion (OME), hearing loss and treatments in children in Cleft Care UK (CCUK) and to examine the association between OME, hearing loss and developmental outcomes at 5 and 7 years. SETTING AND SAMPLE POPULATION:Two hundred and sixty-eight 5-year-old Br...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12184
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:To evaluate root surface changes and resorption following toothborne rapid maxillary expansion (RME) using cone beam computed tomography (CBCT). SETTING AND SAMPLE POPULATION:The Department of Orthodontics at The University of Texas Health Science Center. Twenty-four consecutively treated patients (mean age...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12069
更新日期:2015-04-01 00:00:00
abstract::The mental health of children, adolescents, and adults with orofacial clefts has been studied extensively. Outcomes of interest have included parental adaptation, parent-child attachment, child development, intellectual and academic outcomes, behavioral adaptation, and quality of life. The literature sheds light on me...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00394.x
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:The role of oestrogen in craniofacial growth still remains unclear. Therefore, the present study aimed to assess the effect of oestrogen deficiency on maxilla and mandible dimensions. SETTING AND SAMPLE POPULATION:The study was conducted at the Department of Pediatric Dentistry at the School of Dentistry of ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12376
更新日期:2020-08-01 00:00:00
abstract::The synthesis of tooth development biology with human studies focusing on inherited conditions that specifically interfere with tooth development is improving our understanding of normal and pathological tooth formation. The type of inherited dental malformations observed in a given kindred relate to when, during odon...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00384.x
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:Bone repair strategies continue to be developed for alternatives to autografting, allogeneic implants of banked bone, and other bone substitutes. Efforts have included the delivery of potent growth and/or differentiation factors and the use of gene therapy. For bone regeneration, gene therapy is the delivery...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2005.00332.x
更新日期:2005-08-01 00:00:00
abstract:INTRODUCTION:Functional appliances lead, in different degrees, to loss of anchorage in the lower arch. By anchoring them to the mandibular bone, any dental side effects may be avoided and the skeletal effect enhanced. Stability of bone-borne fixation would be affected by forces created by the pull of the masticatory mu...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12004
更新日期:2013-02-01 00:00:00