Abstract:
OBJECTIVE:To investigate the effects of diabetes on orthodontic tooth movement and orthodontically induced root resorption in rats. SETTING AND SAMPLE POPULATION:Twenty-three 10-week-old male Sprague-Dawley rats divided into control (n = 7), diabetes (n = 9), and diabetes + insulin (n = 7) groups. MATERIALS AND METHODS:Diabetes was induced by administering a single intraperitoneal injection of streptozotocin. Rats with a blood glucose level exceeding 250 mg/dl were assigned to the diabetes group. Insulin was administered daily to the diabetes + insulin group. A nickel-titanium closed-coil spring of 10 g was applied for 2 weeks to the maxillary left first molar in all rats to induce mesial tooth movement. Tooth movement was measured using microcomputed tomography images. To determine the quantity of root resorption, the mesial surfaces of the mesial and distal roots of the first molar were analyzed using both scanning electron microscopy and scanning laser microscopy. RESULTS:After 2 weeks, the amount of tooth movement in the diabetic rats was lower than that in the control rats. Root resorption was also significantly lower in the diabetic rats. These responses of the rats caused by diabetes were mostly diminished by insulin administration. CONCLUSIONS:Diabetes significantly reduced orthodontic tooth movement and orthodontically induced root resorption in rats. The regulation of blood glucose level through insulin administration largely reduced these abnormal responses to orthodontic force application.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Arita K,Hotokezaka H,Hashimoto M,Nakano-Tajima T,Kurohama T,Kondo T,Darendeliler MA,Yoshida Ndoi
10.1111/ocr.12117subject
Has Abstractpub_date
2016-05-01 00:00:00pages
83-92issue
2eissn
1601-6335issn
1601-6343journal_volume
19pub_type
杂志文章abstract::We have developed a cone beam X-ray computed tomography (CT) system to make more accurate three-dimensional (3-D) images for diagnosis of dento-maxillofacial region. The developed system has sufficient spatial resolution, resolution of 3-D images and image distortion for diagnosis of dentomaxillofacial region. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
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abstract:AIMS AND OBJECTIVES:Documentation of dental and orthodontic implications of osteoglophonic dysplasia (OGD). SETTINGS AND PARTICIPANTS:Case report describing oral and dental manifestations of a female with OGD, aged 39 years, who was first documented three decades ago. RESULTS:This rare genetic disorder manifests with...
journal_title:Orthodontics & craniofacial research
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更新日期:2006-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
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abstract::The mental health of children, adolescents, and adults with orofacial clefts has been studied extensively. Outcomes of interest have included parental adaptation, parent-child attachment, child development, intellectual and academic outcomes, behavioral adaptation, and quality of life. The literature sheds light on me...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00394.x
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abstract:OBJECTIVE:Concurrent maxillary and mandibular expansion is a treatment option for patients with maxillary and mandibular transverse constriction. These patients do not present with crossbite but require expansion due to narrow arches and associated crowding, dark buccal corridors and decreased anterior arch contour. Th...
journal_title:Orthodontics & craniofacial research
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journal_title:Orthodontics & craniofacial research
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更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To evaluate cephalometrically craniofacial morphology in children with operated sagittal synostosis and to compare the findings with age- and sex-matched controls. SETTING AND SAMPLE POPULATION:Forty-two children (37 boys) with operated primary sagittal synostosis were compared retrospectively with age- and...
journal_title:Orthodontics & craniofacial research
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journal_title:Orthodontics & craniofacial research
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更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:Three-dimensional evaluation of skeletal mandibular changes following Herbst appliance treatment. SETTING AND SAMPLE POPULATION:Retrospective case-control study, based on a sample size calculation. Twenty-five pubertal patients treated with Herbst appliance (HAG), and 25 matched Class II patients who receiv...
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pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0854.2003.c245.x
更新日期:2003-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12400
更新日期:2021-02-01 00:00:00
abstract:UNLABELLED:AUTHOR: Shen G Objective -This review was compiled to explore the role of type X collagen in growth, development and remodeling of articular cartilage by elucidating the linkage between the synthesis of this protein and the phenotypic changes in chondrogenesis and the onset of endochondral ossification. DES...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2004.00308.x
更新日期:2005-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2006.00340.x
更新日期:2006-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12069
更新日期:2015-04-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2007.00418.x
更新日期:2008-08-01 00:00:00
abstract::This essay briefly considers some underlying concerns about the direction of clinical research in orthodontics. The field is viewed from a personal perspective as things are now, as they are becoming, and as I believe they should be. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00292.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:To measure skull thickness in a group of subjects with skeletal Class II and a group with skeletal Class III malocclusion and compare these results with a group with Class I occlusion. SETTING AND SAMPLE POPULATION:Department of Orthodontics, School of Dentistry, University of Copenhagen. The Class II group...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2008.00434.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To examine the potential role of next-generation sequencing (NGS) and genetic testing to guide preventive care in dental enamel disorders using publicly available databases to access the frequency of deleterious alleles in AMTN, AMLEX and ENAM, associated with amelogenesis imperfecta (AI). SETTING AND SAMPL...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12266
更新日期:2019-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
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更新日期:2005-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12070
更新日期:2015-04-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00417.x
更新日期:2008-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12192
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To introduce a new, fast, reliable, and free from software-related bias method to predict three-dimensionally the root position and angulation during and after orthodontic treatment. The final goal is to keep to a minimum the use of ionizing radiation by eliminating the necessity of multiple radiation exposu...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12252
更新日期:2019-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2009.01463.x
更新日期:2009-11-01 00:00:00
abstract::The skin and the oral mucosa act as a barrier against the external environment. Loss of this barrier function causes dehydration and a high risk of infection. For the treatment of extensive skin wounds such as in severe burns, autologous skin for transplantation is often not available in sufficient amounts. Reconstruc...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2009.01475.x
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:Functional appliances lead, in different degrees, to loss of anchorage in the lower arch. By anchoring them to the mandibular bone, any dental side effects may be avoided and the skeletal effect enhanced. Stability of bone-borne fixation would be affected by forces created by the pull of the masticatory mu...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12004
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVES:To study treatment-related factors for external root resorption during orthodontic tooth movement. DESIGN:An experimental animal study. SETTING AND SAMPLE POPULATION:Department of Orthodontics and Oral Biology, University Medical Centre Nijmegen, The Netherlands. Twenty-four young adult beagle dogs. EXPER...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00283.x
更新日期:2004-05-01 00:00:00