Abstract:
OBJECTIVE:To determine the levels of the receptor activator of NFkB ligand (RANKL) and osteoprotegerin (OPG) in the gingival crevicular fluid (GCF) during orthodontic tooth movement. A second objective was to investigate the effect of compression force on RANKL and OPG production from human periodontal ligament (hPDL) cells. DESIGN:Ten adolescent patients were included. GCF was collected at the distal cervical margins of the experimental and control teeth 0, 1, 24, and 168 h after the retracting force was applied. Thisin vitro study was performed to examine the secretion of RANKL and OPG from hPDL cells following a compression force (0, 0.5, 1.0, 2.0, or 3.0 g/cm(2) for 48 h). Enzyme-linked immunosorbent assay (ELISA) kits were used to determine RANKL and OPG levels in the GCF and the conditioned medium. RESULTS:GCF levels of RANKL were significantly higher, and the levels of OPG significantly lower, in the experimental canines than in the control teeth at 24 h, but there were no such significant differences at 0, 1, or 168 h. In vitro study indicated that the compression force significantly increased the secretion of RANKL and decreased that of OPG in hPDL cells in a time- and force magnitude-dependent manner. The compression-stimulated secretion of RANKL increased approximately 16.7-fold and that of OPG decreased 2.9-fold, as compared with the control. CONCLUSIONS:The results obtained suggest that the changes of amount of RANKL and OPG may be involved in bone resorption as a response to compression force.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Nishijima Y,Yamaguchi M,Kojima T,Aihara N,Nakajima R,Kasai Kdoi
10.1111/j.1601-6343.2006.00340.xsubject
Has Abstractpub_date
2006-05-01 00:00:00pages
63-70issue
2eissn
1601-6335issn
1601-6343pii
OCR340journal_volume
9pub_type
杂志文章abstract::The skin and the oral mucosa act as a barrier against the external environment. Loss of this barrier function causes dehydration and a high risk of infection. For the treatment of extensive skin wounds such as in severe burns, autologous skin for transplantation is often not available in sufficient amounts. Reconstruc...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
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更新日期:2010-02-01 00:00:00
abstract::This essay briefly considers some underlying concerns about the direction of clinical research in orthodontics. The field is viewed from a personal perspective as things are now, as they are becoming, and as I believe they should be. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00292.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:To study treatment-related factors for external root resorption during orthodontic tooth movement. DESIGN:An experimental animal study. SETTING AND SAMPLE POPULATION:Department of Orthodontics and Oral Biology, University Medical Centre Nijmegen, The Netherlands. Twenty-four young adult beagle dogs. EXPER...
journal_title:Orthodontics & craniofacial research
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doi:10.1111/j.1601-6343.2004.00283.x
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abstract:OBJECTIVE:This investigation evaluates the evidence of case-based reasoning (CBR) in providing additional information on the prediction of future Class III craniofacial growth. SETTINGS AND SAMPLE POPULATION:The craniofacial characteristics of 104 untreated Class III subjects (7-17 years of age), monitored with two la...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12466
更新日期:2021-01-08 00:00:00
abstract:AIMS AND OBJECTIVES:Documentation of dental and orthodontic implications of osteoglophonic dysplasia (OGD). SETTINGS AND PARTICIPANTS:Case report describing oral and dental manifestations of a female with OGD, aged 39 years, who was first documented three decades ago. RESULTS:This rare genetic disorder manifests with...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2006.00369.x
更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Hypohidrotic ectodermal dysplasia (HED) is a human heritable disorder characterized by sparse hair, reduced ability to sweat and hypodontia. The HED exhibits X-linked, autosomal recessive and autosomal dominant mode of inheritance. Mutations in four genes including EDA, EDAR, EDARADD, and WNT10A are known ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2011.01521.x
更新日期:2011-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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doi:10.1034/j.1600-0544.2003.03251.x
更新日期:2003-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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更新日期:2017-06-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12387
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:To evaluate whether changes in the concentration of different biomarkers in the gingival crevicular fluid (GCF) can be used to detect the root resorption process in adult or adolescent patients undergoing treatment with a fixed appliance, in comparison with untreated subjects or treated patients not showing ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12329
更新日期:2019-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12129
更新日期:2016-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2011.01525.x
更新日期:2011-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00384.x
更新日期:2007-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2005.00352.x
更新日期:2005-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/ocr.12093
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:Three-dimensional evaluation of skeletal mandibular changes following Herbst appliance treatment. SETTING AND SAMPLE POPULATION:Retrospective case-control study, based on a sample size calculation. Twenty-five pubertal patients treated with Herbst appliance (HAG), and 25 matched Class II patients who receiv...
journal_title:Orthodontics & craniofacial research
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更新日期:2017-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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更新日期:2015-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
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doi:10.1111/j.1601-6343.2005.00332.x
更新日期:2005-08-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00417.x
更新日期:2008-05-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 历史文章,杂志文章
doi:10.1034/j.1600-0544.2003.231.x
更新日期:2003-01-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12184
更新日期:2017-06-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12419
更新日期:2021-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12400
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVES:To assess the effects of a modified alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol in combination with facemask (FM) in Class III growing patients. SETTING AND SAMPLE POPULATION:Thirty one Class III patients (17 males, 14 females) were treated with a modified Alt-RAMEC/FM protocol...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12051
更新日期:2014-11-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12108
更新日期:2016-02-01 00:00:00
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journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01483.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:This study sought to investigate the three-dimensional (3D) changes in anteroposterior, vertical and mediolateral positions and orientations of the mandibular condyle as well as joint space parameters following maxillary first premolar extraction and incisor retraction in skeletal Class II patients. SETTING...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12141
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the stability of Natural Head Position (NHP) over time using the 3dMDface System. SETTING AND SAMPLE POPULATION:This was an experimental study. Three-dimensional facial images of 40 students were captured on two different occasions, with an interval of at least two weeks. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12344
更新日期:2020-02-01 00:00:00
abstract:UNLABELLED:AUTHOR: Shen G Objective -This review was compiled to explore the role of type X collagen in growth, development and remodeling of articular cartilage by elucidating the linkage between the synthesis of this protein and the phenotypic changes in chondrogenesis and the onset of endochondral ossification. DES...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2004.00308.x
更新日期:2005-02-01 00:00:00