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Oral resveratrol supplementation improves Metabolic Syndrome features in obese patients submitted to a lifestyle-changing program.

Abstract：

AIMS:The aim of the present study was to evaluate the oral resveratrol effects associated with diet and physical training changes on anthropometric and biochemical parameters. MAIN METHODS:25 individuals aged from 30 to 60 years old; with Body Mass Index (BMI) ≥ 30 kg/m2 were included in the study. Following the primary evaluation (anthropometric and clinical), the patients were randomly divided into 2 groups: (1) Placebo: Physical activity program + Diet + Placebo; (2) Resveratrol: Physical activity program + Diet + Resveratrol (RVS) (250 mg/day) for three months. Anthropometric and biochemical parameters were evaluated at baseline and after the treatment period. KEY FINDINGS:The main findings showed that the resveratrol supplementation improved total cholesterol (TC), High-density Lipoprotein cholesterol (HDL-c), Very-low density Lipoprotein cholesterol (VLDL-c), urea, creatinine and albumin serum levels. SIGNIFICANCE:These findings indicate that this polyphenol may be an option to potentiate the beneficial effects induced by dietary and physical activity programs in the Metabolic Syndrome (MetS) treatment.

journal_name

Life Sci

journal_title

Life sciences

authors

Batista-Jorge GC,Barcala-Jorge AS,Silveira MF,Lelis DF,Andrade JMO,de Paula AMB,Guimarães ALS,Santos SHS

doi

10.1016/j.lfs.2020.117962

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

117962

eissn

0024-3205

issn

1879-0631

pii

S0024-3205(20)30712-8

journal_volume

256

pub_type

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