Is it tinidazole-induced pancreatitis?

Abstract:

WHAT IS KNOWN AND OBJECTIVE:Metronidazole is one of the drugs with a well-recognized potential to rarely cause acute pancreatitis. The relation of other drugs of the 5-aminoimidazole group (e.g. tinidazole) to acute pancreatitis remains unknown. For the treatment of protozoal infections, tinidazole may be considered as an alternative to metronidazole in cases of intolerability or inadequate response. CASE SUMMARY:We report a case of acute pancreatitis possibly induced by tinidazole. WHAT IS NEW AND CONCLUSION:Tinidazole may probably cause acute pancreatitis similar to metronidazole. Physicians may occasionally encounter an individual with history of metronidazole-induced pancreatitis who requires antiprotozoal therapy. We believe it may be safer to choose a drug outside the 5-aminoimidazole group in this situation.

journal_name

J Clin Pharm Ther

authors

Hegazi MO,Saleh F,John JE

doi

10.1111/jcpt.12307

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

607-608

issue

5

eissn

0269-4727

issn

1365-2710

journal_volume

40

pub_type

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