Fenofibrate-induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database.

Abstract:

WHAT IS KNOWN AND OBJECTIVE:We report a special case of fenofibrate-induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION:The acute severe DILI occurred within only 4 days after fenofibrate initial treatment for hypertriglyceridemia. Liver enzyme levels eventually declined to normal within two weeks after the discontinuation of fenofibrate. WHAT IS NEW AND CONCLUSION:Early detection of elevated hepatic enzymes after fenofibrate initial treatment helps physicians to avoid delayed diagnosis and subsequent treatment.

journal_name

J Clin Pharm Ther

authors

Ma S,Liu S,Wang Q,Chen L,Yang P,Sun H

doi

10.1111/jcpt.13042

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

204-207

issue

1

eissn

0269-4727

issn

1365-2710

journal_volume

45

pub_type

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