Abstract:
INTRODUCTION:The diagnostic approach to patients with isolated asymptomatic cervical lymphadenopathy varies between excisional biopsy and follow-up. When the anamnesis, physical examination, laboratory and imaging findings are not sufficient to identify the etiology, an excisional biopsy is performed for the differential diagnosis between early-stage lymphoma and infectious or reactive causes. If the excisional biopsy, which may have some complications, is not performed, it may delay the diagnosis of lymphoma. This diagnostic challenge could be avoided by predictive markers. OBJECTIVES:This study was planned to determine the predictive value of neutrophil/lymphocyte ratio in the diagnosis of Hodgkin and non-Hodgkin limphoma in patients with asymptomatic, isolated cervical limphadenopathy and underwent excisional biopsy. METHODS:A total of 90 patients between the years 2016-2019 admitted to our clinics due to asymptomatic isolated cervical lymphadenopathy, present in at least 4 weeks with lympho nodes in pathological dimensions persisting in the cervical region, were included to our study. An excisional lympho node biopsy was performed in all 90 patients. RESULTS:Of the 90 patients who underwent excisional biopsy; 34 were diagnosed as reactive lymphadenopathy 30 were non-Hodgkin linphoma, and 26 were Hodgkin linphoma. A total of 56 (62.2%) patients were diagnosed as lymphoma, either Hodgkin or non-Hodgkin, while 34 patients (38.8%) were diagnosed as reactive lymphadenopathy. The median age, total whiteblood count, neutrophil count of the lymphoma groups were significantly higher than reactive lymphadenopathy group, whereas the lymphocyte count was significantly lower in the lymphoma patients. The median neutrophil/ lymphocyte ratio was 1.7 in the reactive lymphadenopathy group, 3.5 in the non-Hodgkin limphoma group, and 3.0 in the Hodgkin limphoma group (p< 0.001). CONCLUSION:According to the results of our study, neutrophil/lymphocyte ratio was significantly higher in patients who were admitted with isolated asymptomatic lymphadenopathy and were diagnosed with lymphoma, and who were diagnosed with early-stage Hodgkin and non- Hodgkin lymphoma compared to those who were found to have reactive lymphadenopathy. Neutrophil/lymphocyte ratio, which is a low-cost, fast and easy-to-access test, has a predictive value in the diagnosis of lymphoma in patients with asymptomatic lymphadenopathy.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Kaplama ME,Güneş AK,Erden Bdoi
10.1016/j.bjorl.2020.06.012subject
Has Abstractpub_date
2020-08-01 00:00:00eissn
1808-8694issn
1808-8686pii
S1808-8694(20)30112-9pub_type
杂志文章abstract:INTRODUCTION:Supratracheal laryngectomy has been described as a surgical procedure for glottic or supraglottic cancer extending to the subglottic region and/or involving the cricoarytenoid joint, aiming to preserve laryngeal function (breathing, phonation and swallowing), without diminishing locoregional cancer control...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.04.004
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The cleft palate is one of the most common congenital anomalies treated by plastic surgeons. The cleft width increases the tension of repair and necessitates excessive dissection that might affect maxillary growth. Decreasing the width of cleft minimize tension, dissection and may limit the impact on maxil...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.04.003
更新日期:2020-05-05 00:00:00
abstract::The treatment of tinnitus, which is defined as conscientious perception of a sound originated in the ears or nervous system, represents until the current days a great challenge. The use of Acupuncture (ACP) is based on the stimulation with needles of specific points on the human anatomy. A prospective, randomized and ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,随机对照试验
doi:10.1016/s1808-8694(15)30053-7
更新日期:2006-03-01 00:00:00
abstract:UNLABELLED:Clinical studies on nasal topical medications require the standardization of 'nasosinusal normality' in order to establish control groups through a specific evaluation of the upper airways. AIM:to standardize the evaluation of candidates for control groups in clinical studies on nasal topical medications. ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30552-8
更新日期:2009-11-01 00:00:00
abstract:UNLABELLED:Because of its biocompatibility and osteoconductive properties, calcium-phosphate cement has been used as bone surrogate. OBJECTIVE:The purpose of this study was to do a histomorphometric comparison of bone regeneration using hydroxyapatite biphasic ceramic, calcium-phosphate cement and autogenous bone graf...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1590/s1808-86942011000400007
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION:In many regions, laryngeal carcinoma is a common upper respiratory tract cancer, most commonly involving the glottic region. The treatment of early glottic cancer includes radiotherapy, open surgery and laryngeal laser microsurgery. However, the preferred treatment for early glottic cancer is still controv...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.06.013
更新日期:2020-08-06 00:00:00
abstract:UNLABELLED:The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM:This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN:A clinical and experimental study. METHODS:A 0...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1590/s1808-86942011000200008
更新日期:2011-03-01 00:00:00
abstract:UNLABELLED:The present study aimed at reporting on the characteristics, prognostic factors and treatment outcomes of 18 cases of nasosinusal mucosa melanoma, and do a literature review on the subject. METHODS:between 1995 and 2005, 18 patients consecutively diagnosed with nasosinusal mucosa melanoma were managed in ou...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1590/s1808-86942011000100010
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The standard therapy for obstructive sleep apnea syndrome (OSAS) is continuous positive airway pressure (CPAP), but its correct and frequent use is essential to control the disease. PURPOSE:To analyze adherence to CPAP among patients with OSAS treated in a multidisciplinary outpatient clinic of a public t...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20140027
更新日期:2014-04-01 00:00:00
abstract:UNLABELLED:Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding and controlling of these mechanisms. AIM:this paper aimed at esta...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/S1808-8694(15)30144-0
更新日期:2008-11-01 00:00:00
abstract:UNLABELLED:Choanal atresia is a rare disease and the incidence is 1: 5000-8000 newborns alive. It is more comom among female and usually is associated with others malformations. STUDY DESIGN:clinical retrospective. When unilateral its diagnose may be postpone because its symptoms are less life threating. But when bila...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31240-4
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Cholesteatoma may occur either in children as in adults; in children, however, they have a more aggressive and extensive growth. OBJECTIVE:To compare the thickness of the perimatrix, in microm, between adults (>18 years old) and children cholesteatomas. STUDY DESIGN:transversal cohort. MATERIAL AND METHOD...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31250-7
更新日期:2005-11-01 00:00:00
abstract:INTRODUCTION:In ideal listening situations, subjects with normal hearing can easily understand speech, as can many subjects who have a hearing loss. OBJECTIVE:To present the validation of the Word Recognition Test in a Free Field in the Presence of Noise in normal-hearing adults. METHODS:Sample consisted of 100 healt...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2016.08.015
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Newborn hearing screening (NHS) programs are implemented across the globe to detect early hearing impairment. In order to meet this objective, the quality of these programs should be monitored using internationally recognized indicators. OBJECTIVE:To evaluate a newborn hearing screening service (NHSS) usi...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.08.008
更新日期:2015-05-01 00:00:00
abstract:UNLABELLED:High-frequency audiometry can detect early changes in auditory sensitivity resulting from processes such as aging. Nonetheless its use is still limited, and additional studies are required to establish its use, particularly among older adults. AIM:To compare pure tone thresholds for frequencies from 250 Hz ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31024-7
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:In different parts of the world, mutations in the GJB2 gene are associated with nonsyndromic hearing loss, and the homozygous 35delG mutation (p.Gly12Valfs*2) is a major cause of hereditary hearing loss. However, the 35delG mutation is not equally prevalent across ethnicities, making it important to study ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.10.013
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:An ongoing discussion is found in medical literature about the reasons for changes in thyroid carcinoma incidence patterns over the last decades. OBJECTIVE:To analyze the clinical and pathological characteristics of thyroid carcinoma cases over a decade. METHODS:Cross-sectional study over an historical c...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.07.015
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:Perceptual evaluation is considered the gold standard to evaluate speech nasality. Several procedures are used to collect and analyze perceptual data, which makes it susceptible to errors. Therefore, there has been an increasing desire to find methods that can improve the assessment. OBJECTIVE:To describe...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.05.017
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:Serum level of high-mobility group box 1 protein is reportedly correlated with the severity of obstructive sleep apnea. OBJECTIVE:We tried to evaluate the possibility of using the serum high-mobility group box 1 protein level as a biologic marker in obstructive sleep apnea patients. METHODS:We generated ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.11.019
更新日期:2021-01-02 00:00:00
abstract:UNLABELLED:Hearing loss is more prevalent than other disorders found at birth. Efforts have been put up towards the early identification and treatment of hearing loss by means of neonatal hearing screening programs. AIM:prospective study with the goal of characterizing the process of implementing a Neonatal Auditory S...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30784-9
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Allergic rhinitis is a chronic inflammatory disease which affects 1 out of 6 individuals. Perennial allergic rhinitis accounts for 40% of AR cases. Ciclesonide is one of the relatively new intranasal steroid for allergic rhinitis. OBJECTIVE:The purpose of this study was to evaluate the efficacy and safety...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,meta分析
doi:10.1016/j.bjorl.2018.10.008
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:Balance disorders affect social, family and professional activities. Vestibular rehabilitation can reduce the impact of these disorders on the quality of life of individuals with vertigo. AIM:to study the influence of vestibular rehabilitation on the quality of life of individuals, correlating it with gende...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract:UNLABELLED:Hearing represents the main source for acquisition of language and speaking skills in childhood. In the first months of life, the hearing impaired child is deprived of sound stimulation in the most important period of development, and consequently, might present emotional, social and linguistic disorders. Th...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30031-8
更新日期:2006-01-01 00:00:00
abstract:UNLABELLED:Myringosclerosis is characterized by hyaline changes of the lamina propria of the tympanic membrane. Experimental studies have used otomicroscopy or histology to evaluate myringosclerosis in animals, but they do not correlate precisely these two methods. AIM:The present study evaluates the accuracy of otomi...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31272-6
更新日期:2005-09-01 00:00:00
abstract:INTRODUCTION:Regional metastases of cutaneous head and neck squamous cell carcinoma occur in approximately 5 % of cases, being the most important prognostic factor in survival, currently with no distinction between parotid and neck metastasis. OBJECTIVE:The purpose of this study was to evaluate the prognostic features...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.10.007
更新日期:2019-11-15 00:00:00
abstract:INTRODUCTION:Bifid uvula is a frequently observed anomaly in the general population and can be regarded as a marker for submucous cleft palate. OBJECTIVE:In this study aimed to determine the frequency of bifid uvula and submucous cleft palate and their relationship with oral clefts in a Brazilian population. METHODS:...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.08.004
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:the Internet is the world's fastest growing source of health related information. Parents and guardians are increasingly turning to the Internet for information about their children's medical conditions and treatments. This paper has the following objectives 1) determine the prevalence of web sear...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract:UNLABELLED:The hormonal changes that occur in a short time span promote modifications all over the woman's body, with physical and emotional manifestations which are frequently observed. AIM:to evaluate the activity of the external ciliated cells in women during their menstrual cycle, observing the effect of hormonal ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30759-x
更新日期:2008-01-01 00:00:00
abstract:UNLABELLED:Children with language or learning impairment and normal hearing need phoniatric assessment to analyse various communication and development aspects targeting the differential diagnosis and therapeutic indications. OBJECTIVE:Characterize clinical and epidemiological features of a pediatric population treate...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20130029
更新日期:2013-03-01 00:00:00
abstract:INTRODUCTION:Methicillin-resistant staphylococcus aureus is an emerging problem for the treatment of chronic suppurative otitis media, and also for pediatric tympanostomy tube otorrhea. To date, there are no effective topical antibiotic drugs to treat methicillin-resistant staphylococcus aureus otorrhea. OBJECTIVE:In ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.05.002
更新日期:2018-01-01 00:00:00