Abstract:
UNLABELLED:The present study aimed at reporting on the characteristics, prognostic factors and treatment outcomes of 18 cases of nasosinusal mucosa melanoma, and do a literature review on the subject. METHODS:between 1995 and 2005, 18 patients consecutively diagnosed with nasosinusal mucosa melanoma were managed in our institution. We reviewed the literature in PubMed and Scopus in order to find the main series from studies associated with this topic. We found a total of 35 series, involving 1,077 patients with nasosinusal mucosa melanoma. RESULTS:we found 16 men and 2 women, with age at presentation between 51 and 80 years (median of 58 years). All these patients were submitted to surgical excision followed by radiotherapy with or without chemotherapy. The survival median was 15 months, and the 5-year general survival had a percentage value of 23%. Considering our univariate analysis: tumor staging and complete remission after initial treatment were deemed relevant prognostic factors. Nonetheless, considering the multivariate analysis, only disease stage was statistically significant. CONCLUSION:nasosinusal melanoma is a rare and aggressive tumor, with high loco-regional and distant failure rates, and poor treatment outcomes. Notwithstanding, in a literature review we found significant improvements considering the 5-year survival for recent series when compared to previously reported ones.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Khademi B,Bahranifard H,Nasrollahi H,Mohammadianpanah Mdoi
10.1590/s1808-86942011000100010subject
Has Abstractpub_date
2011-01-01 00:00:00pages
58-64issue
1eissn
1808-8694issn
1808-8686pii
S1808-8694(15)30942-3journal_volume
77pub_type
杂志文章,评审abstract:INTRODUCTION:Endogenous thyroid-stimulating hormone-stimulated thyroglobulin collected after total thyroidectomy is a useful predictor of better prognosis in patients with differentiated thyroid carcinomas in general, but studies with microcarcinomas are scarce. OBJECTIVE:To assess whether the first postoperative stim...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.10.005
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:p53 tumoral suppressor gene harbors a functional polymorphism which codes either arginine (Arg) or proline (Pro) in the protein p53 of codon 72. Such polymorphism has been associated with the development or prognosis of head and neck squamous cell carcinoma (HNSCC). AIM:we assessed codon 72 p53 allelic freq...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:Migraine is one of the most frequent and incapacitating headaches, with a high degree of impairment in quality of life. Its association with vestibular symptoms is common, including imbalance and postural instability. OBJECTIVE:To evaluate the body balance of patients with vestibular migraine through a st...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.12.001
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:The search for experimental (animal) models is essential to the development of clinical studies. AIM:To demonstrate, by means of micro dissection techniques, the anatomical structures of temporal bones from the primate Callithrix sp. STUDY DESIGN:Experimental. METHODS:Dissection of temporal bone structure...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30570-x
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:Reactive hyperplastic lesions develop in response to a chronic injury simulating an exuberant tissue repair response. They represent some of the most common oral lesions including inflammatory fibrous hyperplasia, oral pyogenic granuloma, giant cell fibroma, peripheral ossifying fibroma, and peripheral gia...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2018.03.006
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:In rhinoplasty, the nasal dorsum has important relevance regarding the esthetic and functional aspects of the surgery. Its reduction should be performed with maximum accuracy and controlled resection to prevent or minimize potential complications. The septum pyramidal adjustment and repositioning consists ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.11.009
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:The impact of the nasal septum morphology on the severity of obstruction symptoms has not been fully explored. OBJECTIVE:This study aimed to investigate whether the morphology of the deviated nasal septum assessed by computed tomography may explain nasal obstruction severity. METHODS:The study included 3...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.09.004
更新日期:2020-10-10 00:00:00
abstract:UNLABELLED:Cholesteatoma may occur either in children as in adults; in children, however, they have a more aggressive and extensive growth. OBJECTIVE:To compare the thickness of the perimatrix, in microm, between adults (>18 years old) and children cholesteatomas. STUDY DESIGN:transversal cohort. MATERIAL AND METHOD...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31250-7
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Nasolabial cyst is a rare lesion situated behind the ala nasi, extending backwards into the inferior nasal meatus and forward into the labio-gingival sulcus. AIM:We present our case of a nasolabial cyst, with the purpose of discussing clinical presentation, diagnosis and the more suitable surgical technique...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30749-7
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Vascular endothelial growth factor is thought to be an important angiogenic factor involved in tumor growth, progression, and metastasis. OBJECTIVE:The present study evaluated the relation between tissue expression, serum and salivary levels of vascular endothelial growth factor in head and neck squamous ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.03.001
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:The standard therapy for obstructive sleep apnea syndrome (OSAS) is continuous positive airway pressure (CPAP), but its correct and frequent use is essential to control the disease. PURPOSE:To analyze adherence to CPAP among patients with OSAS treated in a multidisciplinary outpatient clinic of a public t...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20140027
更新日期:2014-04-01 00:00:00
abstract:UNLABELLED:Rhinoplasty is one of the most challenging surgical procedures, due both to the diversity of the techniques and to the difficulty in foreseeing long-term outcomes. Each patient has a different nasal anatomy, dictated by genetic inheritance--race, thus requiring a different technique for each case. The intern...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30986-1
更新日期:2006-07-01 00:00:00
abstract:UNLABELLED:Hearing impairment (HI) is characterized by unilateral hearing loss in one ear and can result in learning difficulties, language impairment and socio-emotional difficulties. To assess the perception of hearing handicap in adult subjects, patients with unilateral sensorineural HI, non-users of individual hear...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract:UNLABELLED:Children with language or learning impairment and normal hearing need phoniatric assessment to analyse various communication and development aspects targeting the differential diagnosis and therapeutic indications. OBJECTIVE:Characterize clinical and epidemiological features of a pediatric population treate...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20130029
更新日期:2013-03-01 00:00:00
abstract:UNLABELLED:Caloric testing is an otoneurologic evaluation of the status of the vestibular-ocular reflex; it allows an evaluation of each labyrinth separately. The main aspects on the use and interpretation of caloric testing are reviewed. METHOD:A systematic review of papers published in the past one hundred years on ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s1808-8694(15)30580-2
更新日期:2008-05-01 00:00:00
abstract:UNLABELLED:Cleft lip and/or palate represent the most common congenital anomaly of the face. AIM:To describe the correlation between non-syndromic cleft lip and/or palate and gender, and its severity in the Brazilian population. METHODS:Cross-sectional study, between 2009 and 2011, in a sample of 366 patients. The da...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20120018
更新日期:2012-10-01 00:00:00
abstract:INTRODUCTION:A resurgence of syphilis in Brazil has been reported in recent years. OBJECTIVE:With this in mind, the present study sought to investigate the frequency, demographics, and clinical characteristics of patients with acquired syphilis with oral involvement who received medical care at an Oral Medicine Refere...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2018.12.010
更新日期:2020-01-01 00:00:00
abstract:UNLABELLED:To setup an experimental model is the first step to study neural regeneration. AIM:Setting up an experimental model on facial nerve regeneration. MATERIAL AND METHODS:Wistar rats with complete sectioning and suturing of the extratemporal facial nerve trunk; with a behavioral and histological analysis for 9...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma (SCC). Because of its rarity, both clinical and prognostic features of this variant are not well known. OBJECTIVE:In this study, we aimed to determine the frequency of BSCC and other SCC variants among all laryngeal SCC c...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.02.005
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Bifid uvula is a frequently observed anomaly in the general population and can be regarded as a marker for submucous cleft palate. OBJECTIVE:In this study aimed to determine the frequency of bifid uvula and submucous cleft palate and their relationship with oral clefts in a Brazilian population. METHODS:...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.08.004
更新日期:2018-01-01 00:00:00
abstract::Dizziness is one of the most frequent complaints in both primary and specialized medical care facilities. Many dizzy patients, without a known organic cause, considered as having idiopathic dizziness, may have a psychiatric disorder. Besides, even organic dizziness may cause or exacerbate latent psychiatric alteration...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s1808-8694(15)30111-7
更新日期:2007-07-01 00:00:00
abstract:UNLABELLED:The Obstructive Sleep Apnea Syndrome is a chronic disease characterized by episodes upper airway collapse, and has been associated with increased cardiovascular morbidity. AIM:To correlate the neck, abdominal and pelvic circumference with the AHI and oxyhemoglobin saturation in OSA patients, and to correlat...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract:UNLABELLED:To identify the grade and evolution of dysphagia and dysphonia in patients undergoing supracricoid laringectomy, and to study the association of these findings with clinical and surgical variables. METHOD:The study included 22 cases undergoing supracricoid laringectomy at the Head and Neck Surgery and Otola...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31059-4
更新日期:2007-03-01 00:00:00
abstract:UNLABELLED:Ototoxicity of organic solvents can affect the hearing system up to the cochlea level and the central structures of hearing. OBJECTIVE:To evaluate the neurophysiological integrity of the hearing system in subjects exposed to fuels using ABR. METHOD:Prospective study. We evaluated attendants from three gas ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20120035
更新日期:2012-12-01 00:00:00
abstract:UNLABELLED:Hyperbaric oxygen therapy (HBOT) has enhanced the prevention and treatment of auditory ailments such as ototoxicity. OBJECTIVE:To study the effects of HBOT upon ototoxic injuries produced by amikacin. METHOD:This experimental study included 12 albino guinea pigs, whose auditory function was assessed throug...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20130060
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:It is proposed that Helicobacter pylori can be responsible for the development of otitis media with effusion. OBJECTIVE:The aim of this study is to investigate the prevalence of H. pylori in the adenoid tissue and fluid of the middle ear in patients who suffer from adenoid hyperplasia and otitis media wit...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2018.11.002
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Cartilage is the grafting material of choice for certain disorders of the middle ear. The indications for its routine use remain controversial due to the possible detrimental effect on post-operative hearing. OBJECTIVE:The present study was carried out to report a personal experience with "tragal cartilag...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2018.12.006
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Several surgical techniques have been used during tonsillectomy to reduce complications. OBJECTIVES:To assess the effects of pillar suture in conjunction with tonsillectomy as compared to tonsillectomy without suture in children. METHODS:Two authors independently searched five databases (PubMed, SCOPUS, ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.12.007
更新日期:2020-01-25 00:00:00
abstract:INTRODUCTION:Educators dealing with 0-6 years old children must be individuals who are willing to take all kind of measures in order to ensure the safety of children in educational institutions and playgrounds, providing protection from diseases, and who are able to apply first aid measures in case of an accident. OBJ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.06.005
更新日期:2016-07-01 00:00:00
abstract:UNLABELLED:Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding and controlling of these mechanisms. AIM:this paper aimed at esta...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/S1808-8694(15)30144-0
更新日期:2008-11-01 00:00:00